Mutagenetix > Incidental Mutation

Incidental Mutation 'R1445:Dnah7a'

158746

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7a, Dnahc7, LOC381341

MMRRC Submission

039500-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.104) question?

Stock #

R1445 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

53397006-53706784 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 53528797 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Proline to Leucine at position 1880 (P1880L)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000094964
AA Change: P1880L

PolyPhen 2 Score 0.019 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: P1880L

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Meta Mutation Damage Score

0.1024

Coding Region Coverage

1x: 98.8%
3x: 97.7%
10x: 93.9%
20x: 84.0%

Validation Efficiency

96% (101/105)

Allele List at MGI

Other mutations in this stock

Total: 94 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700061I17Rik	G	T	3: 117,067,736		noncoding transcript	Het
2300003K06Rik	G	T	11: 99,837,967	Q17K	probably benign	Het
Abca16	T	C	7: 120,520,033	V999A	probably benign	Het
Actn3	C	T	19: 4,865,455		probably benign	Het
Agap2	T	A	10: 127,091,112		probably benign	Het
Ago3	C	A	4: 126,371,787	R278L	probably benign	Het
Aldh1a2	T	C	9: 71,285,210	V449A	possibly damaging	Het
Alkbh2	C	T	5: 114,124,226	E148K	probably damaging	Het
Aplnr	A	G	2: 85,137,009	Y126C	probably damaging	Het
Apob	T	C	12: 8,016,084	I4351T	possibly damaging	Het
Ash1l	T	C	3: 89,007,352	L1763P	probably benign	Het
Aspn	T	C	13: 49,557,373	S165P	possibly damaging	Het
Atg13	A	T	2: 91,679,990	V349E	probably damaging	Het
Atp1b2	T	A	11: 69,602,483		probably null	Het
B3glct	A	T	5: 149,754,139	D411V	probably damaging	Het
Bcar3	A	T	3: 122,523,191	I255F	probably damaging	Het
Cacna1b	G	A	2: 24,718,136		probably benign	Het
Cep164	T	G	9: 45,778,900	E675A	possibly damaging	Het
Chd1l	C	T	3: 97,582,731	E503K	probably benign	Het
Chst8	C	A	7: 34,748,168	M8I	possibly damaging	Het
Clec4n	A	G	6: 123,235,516	E67G	probably benign	Het
Cobll1	A	T	2: 65,099,136	D653E	probably damaging	Het
Col9a1	T	C	1: 24,237,498		probably null	Het
Crip2	T	C	12: 113,143,504	L30P	probably damaging	Het
Ctbp1	C	T	5: 33,261,063	V22I	probably benign	Het
Cwc22	T	C	2: 77,917,177		probably benign	Het
Cyp4a32	C	A	4: 115,602,950	Y119*	probably null	Het
Dido1	G	T	2: 180,671,470	A463E	possibly damaging	Het
Dock2	T	A	11: 34,239,705	T1489S	probably benign	Het
Dsp	A	G	13: 38,191,931	T1231A	probably damaging	Het
Eif2ak1	G	T	5: 143,873,899		probably benign	Het
Epc1	A	T	18: 6,452,360	M233K	probably damaging	Het
Fam189a2	G	A	19: 24,021,634	T140M	probably damaging	Het
Gigyf2	A	G	1: 87,443,638		probably benign	Het
Greb1	T	G	12: 16,707,851	H58P	probably damaging	Het
Gtpbp1	T	C	15: 79,713,448	I348T	possibly damaging	Het
Hck	A	T	2: 153,128,272	N64Y	probably benign	Het
Herc2	T	C	7: 56,168,996	S2812P	probably damaging	Het
Inpp4b	T	A	8: 81,952,834		probably null	Het
Kcnq5	A	C	1: 21,405,024	S473A	probably benign	Het
Lrat	T	G	3: 82,903,369	D115A	probably damaging	Het
Lyst	A	G	13: 13,640,054	I1131M	possibly damaging	Het
Man2a2	T	C	7: 80,368,562	D160G	probably benign	Het
Marf1	C	T	16: 14,115,824	D1567N	probably benign	Het
Mars	T	C	10: 127,297,988	D680G	possibly damaging	Het
Mat1a	T	C	14: 41,121,840	S339P	probably damaging	Het
Megf8	T	C	7: 25,342,656	S1300P	probably damaging	Het
Mga	T	C	2: 119,902,698	L9S	probably damaging	Het
Mllt6	T	C	11: 97,672,451		probably benign	Het
Mrpl37	A	G	4: 107,064,495	L179P	probably benign	Het
Mtnr1a	G	T	8: 45,087,745	V248L	probably benign	Het
Mylk	T	C	16: 34,815,465	S19P	possibly damaging	Het
Olfr738	A	G	14: 50,414,401	T286A	probably damaging	Het
Parp8	A	T	13: 117,025,350		probably null	Het
Pcnx2	T	C	8: 125,752,284	D2075G	probably damaging	Het
Pigo	A	T	4: 43,021,460	I494K	probably benign	Het
Pkd1l1	A	T	11: 8,870,313	D1217E	probably benign	Het
Pkhd1l1	T	C	15: 44,505,644	V895A	probably benign	Het
Plcb4	A	T	2: 136,000,189	H1031L	possibly damaging	Het
Plxnb1	A	G	9: 109,108,921	K1245R	probably null	Het
Pold1	C	T	7: 44,542,757		probably benign	Het
Ptprq	T	C	10: 107,662,562	I885V	probably damaging	Het
Ptprz1	A	G	6: 23,050,474	D1398G	probably damaging	Het
Pygm	G	A	19: 6,389,887	A364T	probably benign	Het
Rbl1	T	C	2: 157,193,098	N354S	probably benign	Het
Scgb2b19	C	T	7: 33,279,612		probably null	Het
Slc26a8	C	T	17: 28,648,213	V545M	possibly damaging	Het
Slc27a1	T	A	8: 71,584,113		probably null	Het
Smpd1	A	G	7: 105,556,674	D416G	possibly damaging	Het
Sorbs3	A	G	14: 70,193,646	V284A	probably benign	Het
Stfa2l1	T	C	16: 36,161,784	V75A	probably damaging	Het
Syndig1	A	G	2: 149,930,921	D166G	probably damaging	Het
Tcp10a	G	A	17: 7,326,007		probably null	Het
Themis2	T	A	4: 132,782,901	I663F	possibly damaging	Het
Thrap3	T	C	4: 126,176,336	Q586R	probably damaging	Het
Tinag	C	A	9: 77,045,516	C62F	probably damaging	Het
Tmem206	A	G	1: 191,348,362		probably benign	Het
Tmod1	T	C	4: 46,090,884	Y146H	probably damaging	Het
Tmprss4	T	A	9: 45,184,385	I54F	possibly damaging	Het
Tnks	A	C	8: 34,834,603		probably benign	Het
Trim43a	GATTTATTTATTTATTTATTTATTTATTTATTTATTTATT	GATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATT	9: 88,582,989		probably benign	Het
Trpc6	A	G	9: 8,680,537	E844G	probably benign	Het
Ubtd2	C	T	11: 32,516,125	R115W	probably damaging	Het
Ubxn6	T	C	17: 56,069,042	D373G	probably benign	Het
Upf1	T	A	8: 70,341,524	Q244L	probably benign	Het
Usp33	A	G	3: 152,368,634	I372M	probably damaging	Het
Usp34	A	G	11: 23,351,629	E351G	probably damaging	Het
Utrn	A	G	10: 12,678,574		probably benign	Het
Vmn1r78	A	G	7: 12,152,581	K40E	possibly damaging	Het
Vmn2r7	T	A	3: 64,724,802	M80L	probably benign	Het
Vps13a	G	T	19: 16,701,238	Y1126*	probably null	Het
Wfdc11	T	C	2: 164,664,446	N60S	probably benign	Het
Wnk2	C	T	13: 49,071,110	D992N	probably damaging	Het
Zpbp2	C	A	11: 98,553,844	T66K	probably damaging	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53419684	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53501542	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53457746	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53434046	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53434046	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53662381	missense	probably benign
IGL01417:Dnah7a	APN	1	53584600	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53627072	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53419595	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53518782	missense	probably benign
IGL01575:Dnah7a	APN	1	53427820	splice site	probably benign
IGL01667:Dnah7a	APN	1	53547292	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53423270	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53504270	missense	probably benign
IGL01829:Dnah7a	APN	1	53618068	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53640349	missense	probably benign	0.01
IGL01861:Dnah7a	APN	1	53584449	splice site	probably benign
IGL01984:Dnah7a	APN	1	53702015	splice site	probably null
IGL02056:Dnah7a	APN	1	53504342	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53561894	splice site	probably benign
IGL02072:Dnah7a	APN	1	53605827	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53411580	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53495717	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53437513	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53623473	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53472864	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53419723	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53472893	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53643510	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53524937	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53635397	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53686543	missense	probably benign
IGL02458:Dnah7a	APN	1	53618328	nonsense	probably null
IGL02489:Dnah7a	APN	1	53647322	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53618046	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53432915	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53525035	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53504024	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53444472	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53472959	splice site	probably benign
IGL02874:Dnah7a	APN	1	53605814	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53522360	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53577328	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53495950	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53433004	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53605824	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53419607	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53686614	splice site	probably benign
IGL03214:Dnah7a	APN	1	53522209	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53620723	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53647274	missense	probably benign
IGL03265:Dnah7a	APN	1	53528848	missense	probably benign
IGL03277:Dnah7a	APN	1	53630322	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53496965	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53503934	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53531203	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53456874	splice site	probably null
R0051:Dnah7a	UTSW	1	53521086	splice site	probably benign
R0082:Dnah7a	UTSW	1	53518708	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53468684	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53397142	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53501526	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53504146	missense	probably benign	0.00
R0309:Dnah7a	UTSW	1	53405690	missense	probably damaging	0.97
R0334:Dnah7a	UTSW	1	53433054	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53504198	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53605819	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53497126	missense	probably benign
R0576:Dnah7a	UTSW	1	53636087	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53456612	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53497105	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53620681	nonsense	probably null
R0735:Dnah7a	UTSW	1	53544511	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53565696	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53504079	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53501674	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53427860	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53468669	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53647236	splice site	probably benign
R1421:Dnah7a	UTSW	1	53540873	splice site	probably benign
R1473:Dnah7a	UTSW	1	53496014	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53495989	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53456684	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53504185	missense	probably benign	0.18
R1754:Dnah7a	UTSW	1	53561900	critical splice donor site	probably null
R1773:Dnah7a	UTSW	1	53432887	splice site	probably null
R1779:Dnah7a	UTSW	1	53577223	missense	probably benign
R1816:Dnah7a	UTSW	1	53631742	splice site	probably benign
R1817:Dnah7a	UTSW	1	53559148	missense	probably benign
R1818:Dnah7a	UTSW	1	53559148	missense	probably benign
R1819:Dnah7a	UTSW	1	53559148	missense	probably benign
R1873:Dnah7a	UTSW	1	53456532	splice site	probably benign
R1875:Dnah7a	UTSW	1	53456532	splice site	probably benign
R1884:Dnah7a	UTSW	1	53541000	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53535478	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53535478	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53631562	missense	probably benign
R1959:Dnah7a	UTSW	1	53684983	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53684983	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53503934	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53582676	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53582582	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53457696	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53503809	missense	probably benign	0.01
R2124:Dnah7a	UTSW	1	53496942	missense	possibly damaging	0.58
R2191:Dnah7a	UTSW	1	53605875	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53479773	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53521174	missense	probably benign
R2355:Dnah7a	UTSW	1	53582502	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53605881	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53427872	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53427824	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53503554	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53618116	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53444516	missense	probably benign
R3723:Dnah7a	UTSW	1	53447346	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53501656	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53631681	missense	probably benign
R4009:Dnah7a	UTSW	1	53525005	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53425217	missense	probably benign
R4193:Dnah7a	UTSW	1	53447334	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53447365	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53518727	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53444526	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53449038	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53411659	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53456657	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53427951	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53447317	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53425208	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53706729	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53503578	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53698692	missense	probably benign
R5000:Dnah7a	UTSW	1	53567042	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53647248	nonsense	probably null
R5026:Dnah7a	UTSW	1	53662498	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53497096	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53698692	missense	probably benign
R5151:Dnah7a	UTSW	1	53620770	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53643495	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53423287	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53437609	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53447531	splice site	probably null
R5267:Dnah7a	UTSW	1	53479692	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53503646	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53547172	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53631653	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53635344	missense	probably benign
R5496:Dnah7a	UTSW	1	53457768	missense	probably benign
R5531:Dnah7a	UTSW	1	53419748	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53425253	missense	probably benign
R5543:Dnah7a	UTSW	1	53504069	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53534452	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53582594	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53405707	missense	probably benign
R5644:Dnah7a	UTSW	1	53540979	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53405698	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53413778	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53483319	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53457785	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53559308	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53620670	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53559140	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53456845	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53419655	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53411568	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53433022	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53419636	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53503601	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53541114	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53397190	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53503697	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53456534	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53525118	missense	probably benign
R6625:Dnah7a	UTSW	1	53565757	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53623450	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53521226	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53636062	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53698651	missense	probably benign
R6823:Dnah7a	UTSW	1	53456704	missense	probably benign
R6900:Dnah7a	UTSW	1	53662351	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53631677	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53577287	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53662367	missense	probably null
R6988:Dnah7a	UTSW	1	53582625	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53504289	missense	probably benign
R7027:Dnah7a	UTSW	1	53631506	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53479661	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53419753	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53483440	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53413768	nonsense	probably null
R7144:Dnah7a	UTSW	1	53698708	splice site	probably null
R7167:Dnah7a	UTSW	1	53503776	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53620461	splice site	probably null
R7196:Dnah7a	UTSW	1	53684841	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53698633	nonsense	probably null
R7215:Dnah7a	UTSW	1	53618350	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53397261	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53518814	missense	probably benign
R7282:Dnah7a	UTSW	1	53684900	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53497138	missense	probably benign
R7392:Dnah7a	UTSW	1	53501661	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53518764	missense	probably benign
R7471:Dnah7a	UTSW	1	53419699	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53663837	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53528698	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53496005	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53496005	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53547297	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53631683	missense	probably benign
R7813:Dnah7a	UTSW	1	53618086	missense	probably benign
R7839:Dnah7a	UTSW	1	53567175	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53643462	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53504218	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53518727	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53503890	missense	probably benign
R8140:Dnah7a	UTSW	1	53501589	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53627035	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53685019	missense	probably benign
R8352:Dnah7a	UTSW	1	53427827	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53472904	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53472953	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53618036	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53427827	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53617983	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53472908	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53617980	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53640361	missense	probably benign	0.39
R8692:Dnah7a	UTSW	1	53433016	missense	probably benign	0.00
R8700:Dnah7a	UTSW	1	53495929	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53635317	missense	probably benign
R8856:Dnah7a	UTSW	1	53423263	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53643523	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53643435	splice site	probably benign
R8982:Dnah7a	UTSW	1	53531142	missense	probably benign
R8984:Dnah7a	UTSW	1	53635277	nonsense	probably null
R8993:Dnah7a	UTSW	1	53504103	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53662342	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53472957	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53521138	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53702059	missense	unknown
R9167:Dnah7a	UTSW	1	53618211	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53501598	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53521167	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53582512	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53635346	missense	probably benign
R9350:Dnah7a	UTSW	1	53397148	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53504262	missense	probably benign
R9369:Dnah7a	UTSW	1	53525063	missense	possibly damaging	0.72
R9372:Dnah7a	UTSW	1	53504315	missense	probably benign
R9376:Dnah7a	UTSW	1	53528899	critical splice acceptor site	probably null
R9378:Dnah7a	UTSW	1	53582617	missense	probably benign	0.32
R9401:Dnah7a	UTSW	1	53528867	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53411653	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53522336	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53522229	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53559140	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53518809	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53522229	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53472930	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53468643	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53419699	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53483463	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53411656	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53559102	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53643457	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- CCCGTGCTTGGCTCGTATCATAATG -3'
(R):5'- CATGGTTGCAAGGTTTGCCTTGAC -3'

Sequencing Primer
(F):5'- CTAAAACTCAGGGTGTCTGGC -3'
(R):5'- GAATTTGTGCTGCATTGCATCAC -3'

Posted On

2014-03-14