Incidental Mutation 'R1448:Dennd4a'
| ID |
159055 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
039503-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R1448 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 64906045 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 1429
(S1429T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000038890
AA Change: S1429T
PolyPhen 2
Score 0.947 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: S1429T
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000214029
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.8%
- 10x: 94.6%
- 20x: 87.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5330417H12Rik |
T |
A |
7: 107,624,745 (GRCm38) |
|
probably benign |
Het |
| A1cf |
A |
T |
19: 31,908,796 (GRCm38) |
N35I |
possibly damaging |
Het |
| Abca2 |
T |
C |
2: 25,440,530 (GRCm38) |
I1106T |
possibly damaging |
Het |
| Abca4 |
G |
A |
3: 122,162,928 (GRCm38) |
|
probably null |
Het |
| Adgrv1 |
T |
C |
13: 81,433,513 (GRCm38) |
D4804G |
probably benign |
Het |
| Adk |
T |
A |
14: 21,052,640 (GRCm38) |
M1K |
probably null |
Het |
| Aff3 |
T |
C |
1: 38,191,283 (GRCm38) |
N1006D |
probably damaging |
Het |
| Akap12 |
A |
G |
10: 4,355,475 (GRCm38) |
T762A |
probably benign |
Het |
| Atp12a |
T |
A |
14: 56,385,839 (GRCm38) |
M843K |
probably damaging |
Het |
| Bbx |
T |
A |
16: 50,266,270 (GRCm38) |
K169* |
probably null |
Het |
| Bicra |
A |
T |
7: 15,988,359 (GRCm38) |
V411E |
possibly damaging |
Het |
| Camk1d |
A |
T |
2: 5,362,025 (GRCm38) |
Y126* |
probably null |
Het |
| Cel |
T |
C |
2: 28,556,326 (GRCm38) |
Y511C |
probably damaging |
Het |
| Celf4 |
G |
T |
18: 25,503,083 (GRCm38) |
|
probably null |
Het |
| Clasp1 |
A |
G |
1: 118,508,916 (GRCm38) |
N310S |
probably benign |
Het |
| Col6a3 |
T |
C |
1: 90,781,855 (GRCm38) |
K1873R |
unknown |
Het |
| Cstf1 |
A |
G |
2: 172,375,875 (GRCm38) |
D136G |
probably damaging |
Het |
| Cwc22 |
T |
A |
2: 77,911,555 (GRCm38) |
E470D |
probably damaging |
Het |
| Cxcr2 |
A |
T |
1: 74,158,368 (GRCm38) |
D7V |
probably benign |
Het |
| Cytip |
A |
G |
2: 58,145,180 (GRCm38) |
I168T |
probably damaging |
Het |
| D5Ertd579e |
A |
G |
5: 36,602,739 (GRCm38) |
L1359P |
probably benign |
Het |
| Ddx25 |
A |
C |
9: 35,557,738 (GRCm38) |
V26G |
probably benign |
Het |
| Dmd |
A |
G |
X: 84,848,700 (GRCm38) |
D2990G |
probably damaging |
Het |
| Dopey1 |
C |
A |
9: 86,542,732 (GRCm38) |
|
probably null |
Het |
| Eps8 |
T |
C |
6: 137,522,854 (GRCm38) |
Q209R |
possibly damaging |
Het |
| Fabp6 |
T |
A |
11: 43,596,165 (GRCm38) |
I112F |
probably benign |
Het |
| Fam159b |
T |
C |
13: 104,845,962 (GRCm38) |
I151V |
probably benign |
Het |
| Fam214a |
C |
G |
9: 75,010,174 (GRCm38) |
S685* |
probably null |
Het |
| Fbxw10 |
T |
C |
11: 62,847,592 (GRCm38) |
V104A |
possibly damaging |
Het |
| Gp1ba |
C |
T |
11: 70,641,427 (GRCm38) |
P673L |
probably damaging |
Het |
| Grin3a |
T |
C |
4: 49,702,804 (GRCm38) |
Y894C |
probably damaging |
Het |
| Hydin |
C |
T |
8: 110,446,585 (GRCm38) |
H967Y |
probably benign |
Het |
| Ip6k3 |
T |
C |
17: 27,145,268 (GRCm38) |
K269E |
possibly damaging |
Het |
| Jup |
T |
C |
11: 100,383,200 (GRCm38) |
K172E |
probably damaging |
Het |
| Katnal1 |
T |
C |
5: 148,904,676 (GRCm38) |
D126G |
probably benign |
Het |
| Knl1 |
A |
T |
2: 119,068,307 (GRCm38) |
K163M |
probably damaging |
Het |
| Krt17 |
C |
T |
11: 100,257,539 (GRCm38) |
E359K |
possibly damaging |
Het |
| Lct |
T |
A |
1: 128,307,822 (GRCm38) |
I483F |
probably damaging |
Het |
| Loxl2 |
G |
A |
14: 69,693,040 (GRCm38) |
G751D |
probably damaging |
Het |
| Ltbp4 |
G |
A |
7: 27,306,577 (GRCm38) |
R1559C |
possibly damaging |
Het |
| Man2c1 |
T |
A |
9: 57,135,219 (GRCm38) |
D183E |
probably benign |
Het |
| Med17 |
T |
C |
9: 15,275,843 (GRCm38) |
|
probably null |
Het |
| Mrgpra9 |
A |
C |
7: 47,235,813 (GRCm38) |
S34R |
probably benign |
Het |
| Mrpl44 |
T |
A |
1: 79,777,960 (GRCm38) |
N94K |
probably damaging |
Het |
| Nat8f1 |
A |
G |
6: 85,910,942 (GRCm38) |
V12A |
probably benign |
Het |
| Nr2e3 |
C |
A |
9: 59,943,514 (GRCm38) |
G354V |
probably damaging |
Het |
| Nrbp1 |
T |
A |
5: 31,245,813 (GRCm38) |
I210N |
probably damaging |
Het |
| Nup155 |
T |
C |
15: 8,112,406 (GRCm38) |
V94A |
probably benign |
Het |
| Olfr1497 |
A |
T |
19: 13,794,776 (GRCm38) |
Y278* |
probably null |
Het |
| Olfr294 |
A |
T |
7: 86,616,361 (GRCm38) |
C95S |
probably damaging |
Het |
| Olfr502 |
T |
C |
7: 108,523,318 (GRCm38) |
I211V |
probably benign |
Het |
| Olfr649 |
C |
T |
7: 104,189,875 (GRCm38) |
V111I |
possibly damaging |
Het |
| Pcdhb10 |
A |
T |
18: 37,412,503 (GRCm38) |
I211F |
possibly damaging |
Het |
| Phip |
A |
C |
9: 82,915,423 (GRCm38) |
I509S |
possibly damaging |
Het |
| Pkhd1 |
C |
T |
1: 20,585,157 (GRCm38) |
|
probably null |
Het |
| Psme4 |
T |
G |
11: 30,852,744 (GRCm38) |
L1487R |
probably damaging |
Het |
| Ptgdr2 |
A |
G |
19: 10,940,493 (GRCm38) |
S125G |
probably damaging |
Het |
| Ptpro |
A |
G |
6: 137,441,116 (GRCm38) |
K126E |
probably damaging |
Het |
| Rdh16f2 |
T |
A |
10: 127,876,925 (GRCm38) |
V264E |
probably benign |
Het |
| Ric8b |
C |
T |
10: 84,947,671 (GRCm38) |
A131V |
possibly damaging |
Het |
| Rock1 |
A |
T |
18: 10,070,233 (GRCm38) |
I1280N |
probably damaging |
Het |
| Rprd2 |
A |
G |
3: 95,818,576 (GRCm38) |
V59A |
possibly damaging |
Het |
| Ruvbl1 |
T |
A |
6: 88,467,569 (GRCm38) |
C49S |
probably benign |
Het |
| Scn2a |
A |
G |
2: 65,683,845 (GRCm38) |
N291S |
probably benign |
Het |
| Serbp1 |
T |
A |
6: 67,277,920 (GRCm38) |
H325Q |
probably damaging |
Het |
| Shf |
G |
A |
2: 122,368,682 (GRCm38) |
P51S |
probably damaging |
Het |
| Slitrk3 |
G |
A |
3: 73,050,341 (GRCm38) |
T366I |
probably damaging |
Het |
| Spryd3 |
A |
T |
15: 102,118,392 (GRCm38) |
H307Q |
possibly damaging |
Het |
| Spx |
A |
T |
6: 142,418,513 (GRCm38) |
D100V |
probably benign |
Het |
| Surf4 |
A |
G |
2: 26,924,464 (GRCm38) |
F142L |
probably damaging |
Het |
| Syne2 |
T |
C |
12: 76,052,178 (GRCm38) |
M5278T |
possibly damaging |
Het |
| Syne2 |
T |
A |
12: 76,020,325 (GRCm38) |
|
probably null |
Het |
| Thap12 |
T |
C |
7: 98,716,023 (GRCm38) |
V466A |
probably benign |
Het |
| Thap3 |
T |
C |
4: 151,983,216 (GRCm38) |
K135R |
possibly damaging |
Het |
| Tmem131 |
G |
T |
1: 36,827,358 (GRCm38) |
D448E |
probably benign |
Het |
| Tmem63b |
C |
G |
17: 45,678,978 (GRCm38) |
R88P |
possibly damaging |
Het |
| Trim43a |
G |
T |
9: 88,582,093 (GRCm38) |
C19F |
probably damaging |
Het |
| Trp63 |
C |
T |
16: 25,889,120 (GRCm38) |
P526L |
possibly damaging |
Het |
| Ubqln3 |
T |
C |
7: 104,142,790 (GRCm38) |
D31G |
probably damaging |
Het |
| Utp14b |
C |
A |
1: 78,665,445 (GRCm38) |
N353K |
probably damaging |
Het |
| Vmn1r40 |
A |
G |
6: 89,714,576 (GRCm38) |
K125R |
probably damaging |
Het |
| Vmn2r1 |
A |
G |
3: 64,101,313 (GRCm38) |
Y471C |
probably damaging |
Het |
| Vmn2r13 |
A |
G |
5: 109,174,135 (GRCm38) |
I232T |
probably damaging |
Het |
| Zfp263 |
A |
C |
16: 3,746,459 (GRCm38) |
E204D |
probably benign |
Het |
| Zfp865 |
A |
T |
7: 5,029,279 (GRCm38) |
K88* |
probably null |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTGCAGACATGCCTCAGCTTC -3'
(R):5'- AACAGGTCTCAGCAACCTTGGATG -3'
Sequencing Primer
(F):5'- ggaatgggaagcagtggtag -3'
(R):5'- CTCAGCAACCTTGGATGTAATGG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation