Incidental Mutation 'R1449:Kif13a'
| ID |
159161 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| MMRRC Submission |
039504-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.268)
|
| Stock # |
R1449 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46966212 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 402
(Y402C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153614
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056978
AA Change: Y465C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: Y465C
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225591
AA Change: Y402C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.9%
- 10x: 94.7%
- 20x: 87.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013G24Rik |
A |
G |
4: 137,182,666 (GRCm39) |
N274D |
possibly damaging |
Het |
| 6430571L13Rik |
T |
A |
9: 107,219,689 (GRCm39) |
N47K |
probably damaging |
Het |
| Aasdh |
C |
T |
5: 77,034,136 (GRCm39) |
A472T |
probably benign |
Het |
| Abca13 |
A |
G |
11: 9,248,580 (GRCm39) |
T2776A |
probably damaging |
Het |
| Adamts10 |
T |
A |
17: 33,764,613 (GRCm39) |
V711D |
probably damaging |
Het |
| Adrb3 |
G |
A |
8: 27,717,415 (GRCm39) |
R345C |
probably damaging |
Het |
| Ak7 |
T |
C |
12: 105,708,520 (GRCm39) |
V325A |
possibly damaging |
Het |
| Armc6 |
G |
A |
8: 70,677,943 (GRCm39) |
L129F |
probably benign |
Het |
| Bend6 |
T |
C |
1: 33,917,424 (GRCm39) |
N10S |
probably benign |
Het |
| Bmpr1b |
T |
C |
3: 141,577,134 (GRCm39) |
E59G |
possibly damaging |
Het |
| Brd3 |
A |
G |
2: 27,340,263 (GRCm39) |
|
probably null |
Het |
| Brd3 |
A |
G |
2: 27,347,028 (GRCm39) |
Y369H |
probably damaging |
Het |
| Cacna1e |
C |
T |
1: 154,361,408 (GRCm39) |
|
probably null |
Het |
| Camk4 |
A |
G |
18: 33,072,528 (GRCm39) |
D27G |
probably damaging |
Het |
| Camkk1 |
T |
G |
11: 72,924,710 (GRCm39) |
S308A |
probably damaging |
Het |
| Catsperb |
A |
G |
12: 101,554,456 (GRCm39) |
T717A |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,212,730 (GRCm39) |
S1563R |
probably damaging |
Het |
| Cep44 |
A |
T |
8: 56,993,985 (GRCm39) |
S197R |
probably benign |
Het |
| Col3a1 |
T |
A |
1: 45,360,771 (GRCm39) |
I67N |
unknown |
Het |
| Dcaf12l1 |
T |
C |
X: 43,878,304 (GRCm39) |
T165A |
probably benign |
Het |
| Dicer1 |
T |
C |
12: 104,695,502 (GRCm39) |
Y143C |
possibly damaging |
Het |
| Dlg5 |
A |
G |
14: 24,185,711 (GRCm39) |
I1898T |
possibly damaging |
Het |
| Dnah1 |
T |
C |
14: 30,985,908 (GRCm39) |
N3762D |
probably damaging |
Het |
| Dscaml1 |
A |
T |
9: 45,653,521 (GRCm39) |
T1382S |
possibly damaging |
Het |
| Entpd3 |
A |
T |
9: 120,395,555 (GRCm39) |
R513W |
probably damaging |
Het |
| Foxred1 |
A |
G |
9: 35,120,738 (GRCm39) |
S132P |
probably damaging |
Het |
| Ftsj3 |
T |
C |
11: 106,143,826 (GRCm39) |
I273V |
probably benign |
Het |
| Hsd17b7 |
C |
T |
1: 169,787,251 (GRCm39) |
|
probably null |
Het |
| Iars1 |
T |
A |
13: 49,887,186 (GRCm39) |
V1253D |
probably damaging |
Het |
| Iqsec1 |
T |
A |
6: 90,667,790 (GRCm39) |
K216* |
probably null |
Het |
| Itga7 |
A |
G |
10: 128,789,370 (GRCm39) |
D971G |
probably benign |
Het |
| Kcnk2 |
G |
A |
1: 189,072,223 (GRCm39) |
S35L |
probably benign |
Het |
| Lamc1 |
A |
G |
1: 153,126,241 (GRCm39) |
S484P |
probably benign |
Het |
| Lap3 |
T |
C |
5: 45,666,861 (GRCm39) |
|
probably null |
Het |
| Lhx8 |
G |
T |
3: 154,033,742 (GRCm39) |
S46* |
probably null |
Het |
| Lin7a |
T |
C |
10: 107,159,813 (GRCm39) |
S42P |
probably damaging |
Het |
| Lrba |
G |
A |
3: 86,261,585 (GRCm39) |
R1513Q |
probably damaging |
Het |
| Maml2 |
C |
A |
9: 13,531,980 (GRCm39) |
P398Q |
possibly damaging |
Het |
| Mast2 |
T |
C |
4: 116,166,210 (GRCm39) |
I1201V |
probably damaging |
Het |
| Mmp20 |
A |
T |
9: 7,642,769 (GRCm39) |
D201V |
probably damaging |
Het |
| Morn5 |
T |
A |
2: 35,947,092 (GRCm39) |
C123* |
probably null |
Het |
| Mrpl4 |
A |
G |
9: 20,918,807 (GRCm39) |
K175E |
possibly damaging |
Het |
| Nav3 |
A |
T |
10: 109,689,372 (GRCm39) |
S302T |
probably benign |
Het |
| Ndrg2 |
T |
C |
14: 52,145,591 (GRCm39) |
Y217C |
probably damaging |
Het |
| Nfx1 |
A |
G |
4: 40,976,803 (GRCm39) |
D159G |
probably damaging |
Het |
| Nlrp9b |
A |
T |
7: 19,757,089 (GRCm39) |
T109S |
possibly damaging |
Het |
| Npepps |
A |
G |
11: 97,097,980 (GRCm39) |
Y909H |
probably benign |
Het |
| Or10g1 |
A |
G |
14: 52,648,024 (GRCm39) |
C102R |
probably damaging |
Het |
| Or11g7 |
A |
G |
14: 50,691,378 (GRCm39) |
N290D |
probably damaging |
Het |
| Or51a25 |
A |
T |
7: 102,373,397 (GRCm39) |
F100Y |
probably damaging |
Het |
| Or6c211 |
T |
A |
10: 129,506,238 (GRCm39) |
D50V |
probably damaging |
Het |
| Or6c69b |
A |
C |
10: 129,626,723 (GRCm39) |
V245G |
probably damaging |
Het |
| Pcdh1 |
T |
C |
18: 38,322,929 (GRCm39) |
H968R |
probably damaging |
Het |
| Pde1b |
T |
A |
15: 103,433,470 (GRCm39) |
I296N |
probably damaging |
Het |
| Phldb1 |
T |
A |
9: 44,627,930 (GRCm39) |
T172S |
probably benign |
Het |
| Plxdc2 |
T |
C |
2: 16,665,592 (GRCm39) |
V215A |
possibly damaging |
Het |
| Poln |
A |
G |
5: 34,171,682 (GRCm39) |
I695T |
probably damaging |
Het |
| Pou6f2 |
G |
T |
13: 18,347,000 (GRCm39) |
Q31K |
probably damaging |
Het |
| Psd |
T |
A |
19: 46,313,250 (GRCm39) |
Y40F |
probably damaging |
Het |
| Rnf126 |
T |
C |
10: 79,597,448 (GRCm39) |
N155D |
probably benign |
Het |
| Rpl36-ps3 |
C |
A |
12: 12,962,032 (GRCm39) |
|
noncoding transcript |
Het |
| Rrp15 |
C |
A |
1: 186,468,465 (GRCm39) |
V184F |
possibly damaging |
Het |
| Rslcan18 |
G |
T |
13: 67,250,164 (GRCm39) |
L24M |
possibly damaging |
Het |
| Sall1 |
A |
G |
8: 89,759,111 (GRCm39) |
I331T |
probably benign |
Het |
| Slamf7 |
A |
T |
1: 171,468,606 (GRCm39) |
N95K |
possibly damaging |
Het |
| Slc1a6 |
T |
C |
10: 78,635,951 (GRCm39) |
Y339H |
probably damaging |
Het |
| Slc39a8 |
A |
G |
3: 135,532,446 (GRCm39) |
N72D |
probably benign |
Het |
| Slf1 |
A |
G |
13: 77,231,568 (GRCm39) |
S604P |
probably damaging |
Het |
| Slfn4 |
C |
T |
11: 83,079,819 (GRCm39) |
T110M |
probably benign |
Het |
| Tnpo1 |
T |
C |
13: 99,015,220 (GRCm39) |
T116A |
probably damaging |
Het |
| Tor1b |
T |
C |
2: 30,845,893 (GRCm39) |
I190T |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,800,138 (GRCm39) |
E357* |
probably null |
Het |
| Tubg2 |
G |
T |
11: 101,047,699 (GRCm39) |
E95* |
probably null |
Het |
| Ubap2 |
A |
G |
4: 41,209,351 (GRCm39) |
|
probably null |
Het |
| Ube2i |
T |
C |
17: 25,487,538 (GRCm39) |
D67G |
possibly damaging |
Het |
| Ubxn11 |
A |
G |
4: 133,852,203 (GRCm39) |
E50G |
probably damaging |
Het |
| Wnk1 |
A |
G |
6: 119,929,779 (GRCm39) |
V1246A |
probably damaging |
Het |
| Zcchc7 |
A |
G |
4: 44,929,124 (GRCm39) |
T38A |
possibly damaging |
Het |
| Zfp236 |
A |
G |
18: 82,664,130 (GRCm39) |
S552P |
probably damaging |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0403:Kif13a
|
UTSW |
13 |
46,944,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2016:Kif13a
|
UTSW |
13 |
46,964,275 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Kif13a
|
UTSW |
13 |
46,980,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8098:Kif13a
|
UTSW |
13 |
46,968,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8871:Kif13a
|
UTSW |
13 |
46,984,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCCCTCTGGAAACTGTCCTCAAG -3'
(R):5'- AGCCGACACTGTGTGTTTCACC -3'
Sequencing Primer
(F):5'- AACTGTCCTCAAGGGCATGG -3'
(R):5'- TGCGGCCCTTAGTAAACTCAG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation