Incidental Mutation 'R1449:Zfp236'
| ID |
159180 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp236
|
| Ensembl Gene |
ENSMUSG00000041258 |
| Gene Name |
zinc finger protein 236 |
| Synonyms |
LOC240456 |
| MMRRC Submission |
039504-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1449 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
82611718-82711008 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 82664130 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 552
(S552P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138557
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000171071]
[ENSMUST00000182122]
[ENSMUST00000183048]
|
| AlphaFold |
S4R299 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171071
AA Change: S504P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130004
Gene: ENSMUSG00000041258
AA Change: S504P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
low complexity region
|
290 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
403 |
426 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
436 |
458 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
464 |
486 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
492 |
514 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
520 |
542 |
1.18e-2 |
SMART |
|
low complexity region
|
592 |
605 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
611 |
633 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
639 |
661 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
667 |
689 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
695 |
717 |
7.37e-4 |
SMART |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
922 |
944 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
950 |
972 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
978 |
1000 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1006 |
1028 |
2.75e-3 |
SMART |
|
low complexity region
|
1030 |
1039 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1122 |
1144 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1150 |
1172 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1178 |
1200 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1206 |
1228 |
5.42e-2 |
SMART |
|
low complexity region
|
1243 |
1258 |
N/A |
INTRINSIC |
|
low complexity region
|
1462 |
1477 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1612 |
1635 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1641 |
1663 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1677 |
1699 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1705 |
1727 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1733 |
1756 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182122
AA Change: S552P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000138557
Gene: ENSMUSG00000041258
AA Change: S552P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
474 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
484 |
506 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
512 |
534 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
540 |
562 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
568 |
590 |
1.18e-2 |
SMART |
|
low complexity region
|
640 |
653 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
659 |
681 |
1.62e0 |
SMART |
|
ZnF_C2H2
|
687 |
709 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
715 |
737 |
6.78e-3 |
SMART |
|
ZnF_C2H2
|
743 |
765 |
7.37e-4 |
SMART |
|
low complexity region
|
768 |
781 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
970 |
992 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
998 |
1020 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
1026 |
1048 |
8.6e-5 |
SMART |
|
ZnF_C2H2
|
1054 |
1076 |
2.75e-3 |
SMART |
|
low complexity region
|
1078 |
1087 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
1198 |
1220 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
1226 |
1248 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
1254 |
1276 |
5.42e-2 |
SMART |
|
low complexity region
|
1291 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1510 |
1525 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1660 |
1683 |
7.15e-2 |
SMART |
|
ZnF_C2H2
|
1689 |
1711 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
1725 |
1747 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
1753 |
1775 |
1.84e-4 |
SMART |
|
ZnF_C2H2
|
1781 |
1804 |
2.95e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183048
|
| SMART Domains |
Protein: ENSMUSP00000138179
Gene: ENSMUSG00000041258
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
39 |
61 |
2.24e-3 |
SMART |
|
ZnF_C2H2
|
68 |
90 |
2.29e0 |
SMART |
|
ZnF_C2H2
|
95 |
117 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
123 |
145 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
155 |
177 |
6.42e-4 |
SMART |
|
ZnF_C2H2
|
199 |
221 |
1.75e-5 |
SMART |
|
ZnF_C2H2
|
227 |
249 |
1.52e-5 |
SMART |
|
ZnF_C2H2
|
255 |
278 |
8.94e-3 |
SMART |
|
ZnF_C2H2
|
287 |
310 |
9.58e-3 |
SMART |
|
low complexity region
|
338 |
357 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
467 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.9%
- 10x: 94.7%
- 20x: 87.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013G24Rik |
A |
G |
4: 137,182,666 (GRCm39) |
N274D |
possibly damaging |
Het |
| 6430571L13Rik |
T |
A |
9: 107,219,689 (GRCm39) |
N47K |
probably damaging |
Het |
| Aasdh |
C |
T |
5: 77,034,136 (GRCm39) |
A472T |
probably benign |
Het |
| Abca13 |
A |
G |
11: 9,248,580 (GRCm39) |
T2776A |
probably damaging |
Het |
| Adamts10 |
T |
A |
17: 33,764,613 (GRCm39) |
V711D |
probably damaging |
Het |
| Adrb3 |
G |
A |
8: 27,717,415 (GRCm39) |
R345C |
probably damaging |
Het |
| Ak7 |
T |
C |
12: 105,708,520 (GRCm39) |
V325A |
possibly damaging |
Het |
| Armc6 |
G |
A |
8: 70,677,943 (GRCm39) |
L129F |
probably benign |
Het |
| Bend6 |
T |
C |
1: 33,917,424 (GRCm39) |
N10S |
probably benign |
Het |
| Bmpr1b |
T |
C |
3: 141,577,134 (GRCm39) |
E59G |
possibly damaging |
Het |
| Brd3 |
A |
G |
2: 27,340,263 (GRCm39) |
|
probably null |
Het |
| Brd3 |
A |
G |
2: 27,347,028 (GRCm39) |
Y369H |
probably damaging |
Het |
| Cacna1e |
C |
T |
1: 154,361,408 (GRCm39) |
|
probably null |
Het |
| Camk4 |
A |
G |
18: 33,072,528 (GRCm39) |
D27G |
probably damaging |
Het |
| Camkk1 |
T |
G |
11: 72,924,710 (GRCm39) |
S308A |
probably damaging |
Het |
| Catsperb |
A |
G |
12: 101,554,456 (GRCm39) |
T717A |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,212,730 (GRCm39) |
S1563R |
probably damaging |
Het |
| Cep44 |
A |
T |
8: 56,993,985 (GRCm39) |
S197R |
probably benign |
Het |
| Col3a1 |
T |
A |
1: 45,360,771 (GRCm39) |
I67N |
unknown |
Het |
| Dcaf12l1 |
T |
C |
X: 43,878,304 (GRCm39) |
T165A |
probably benign |
Het |
| Dicer1 |
T |
C |
12: 104,695,502 (GRCm39) |
Y143C |
possibly damaging |
Het |
| Dlg5 |
A |
G |
14: 24,185,711 (GRCm39) |
I1898T |
possibly damaging |
Het |
| Dnah1 |
T |
C |
14: 30,985,908 (GRCm39) |
N3762D |
probably damaging |
Het |
| Dscaml1 |
A |
T |
9: 45,653,521 (GRCm39) |
T1382S |
possibly damaging |
Het |
| Entpd3 |
A |
T |
9: 120,395,555 (GRCm39) |
R513W |
probably damaging |
Het |
| Foxred1 |
A |
G |
9: 35,120,738 (GRCm39) |
S132P |
probably damaging |
Het |
| Ftsj3 |
T |
C |
11: 106,143,826 (GRCm39) |
I273V |
probably benign |
Het |
| Hsd17b7 |
C |
T |
1: 169,787,251 (GRCm39) |
|
probably null |
Het |
| Iars1 |
T |
A |
13: 49,887,186 (GRCm39) |
V1253D |
probably damaging |
Het |
| Iqsec1 |
T |
A |
6: 90,667,790 (GRCm39) |
K216* |
probably null |
Het |
| Itga7 |
A |
G |
10: 128,789,370 (GRCm39) |
D971G |
probably benign |
Het |
| Kcnk2 |
G |
A |
1: 189,072,223 (GRCm39) |
S35L |
probably benign |
Het |
| Kif13a |
T |
C |
13: 46,966,212 (GRCm39) |
Y402C |
probably damaging |
Het |
| Lamc1 |
A |
G |
1: 153,126,241 (GRCm39) |
S484P |
probably benign |
Het |
| Lap3 |
T |
C |
5: 45,666,861 (GRCm39) |
|
probably null |
Het |
| Lhx8 |
G |
T |
3: 154,033,742 (GRCm39) |
S46* |
probably null |
Het |
| Lin7a |
T |
C |
10: 107,159,813 (GRCm39) |
S42P |
probably damaging |
Het |
| Lrba |
G |
A |
3: 86,261,585 (GRCm39) |
R1513Q |
probably damaging |
Het |
| Maml2 |
C |
A |
9: 13,531,980 (GRCm39) |
P398Q |
possibly damaging |
Het |
| Mast2 |
T |
C |
4: 116,166,210 (GRCm39) |
I1201V |
probably damaging |
Het |
| Mmp20 |
A |
T |
9: 7,642,769 (GRCm39) |
D201V |
probably damaging |
Het |
| Morn5 |
T |
A |
2: 35,947,092 (GRCm39) |
C123* |
probably null |
Het |
| Mrpl4 |
A |
G |
9: 20,918,807 (GRCm39) |
K175E |
possibly damaging |
Het |
| Nav3 |
A |
T |
10: 109,689,372 (GRCm39) |
S302T |
probably benign |
Het |
| Ndrg2 |
T |
C |
14: 52,145,591 (GRCm39) |
Y217C |
probably damaging |
Het |
| Nfx1 |
A |
G |
4: 40,976,803 (GRCm39) |
D159G |
probably damaging |
Het |
| Nlrp9b |
A |
T |
7: 19,757,089 (GRCm39) |
T109S |
possibly damaging |
Het |
| Npepps |
A |
G |
11: 97,097,980 (GRCm39) |
Y909H |
probably benign |
Het |
| Or10g1 |
A |
G |
14: 52,648,024 (GRCm39) |
C102R |
probably damaging |
Het |
| Or11g7 |
A |
G |
14: 50,691,378 (GRCm39) |
N290D |
probably damaging |
Het |
| Or51a25 |
A |
T |
7: 102,373,397 (GRCm39) |
F100Y |
probably damaging |
Het |
| Or6c211 |
T |
A |
10: 129,506,238 (GRCm39) |
D50V |
probably damaging |
Het |
| Or6c69b |
A |
C |
10: 129,626,723 (GRCm39) |
V245G |
probably damaging |
Het |
| Pcdh1 |
T |
C |
18: 38,322,929 (GRCm39) |
H968R |
probably damaging |
Het |
| Pde1b |
T |
A |
15: 103,433,470 (GRCm39) |
I296N |
probably damaging |
Het |
| Phldb1 |
T |
A |
9: 44,627,930 (GRCm39) |
T172S |
probably benign |
Het |
| Plxdc2 |
T |
C |
2: 16,665,592 (GRCm39) |
V215A |
possibly damaging |
Het |
| Poln |
A |
G |
5: 34,171,682 (GRCm39) |
I695T |
probably damaging |
Het |
| Pou6f2 |
G |
T |
13: 18,347,000 (GRCm39) |
Q31K |
probably damaging |
Het |
| Psd |
T |
A |
19: 46,313,250 (GRCm39) |
Y40F |
probably damaging |
Het |
| Rnf126 |
T |
C |
10: 79,597,448 (GRCm39) |
N155D |
probably benign |
Het |
| Rpl36-ps3 |
C |
A |
12: 12,962,032 (GRCm39) |
|
noncoding transcript |
Het |
| Rrp15 |
C |
A |
1: 186,468,465 (GRCm39) |
V184F |
possibly damaging |
Het |
| Rslcan18 |
G |
T |
13: 67,250,164 (GRCm39) |
L24M |
possibly damaging |
Het |
| Sall1 |
A |
G |
8: 89,759,111 (GRCm39) |
I331T |
probably benign |
Het |
| Slamf7 |
A |
T |
1: 171,468,606 (GRCm39) |
N95K |
possibly damaging |
Het |
| Slc1a6 |
T |
C |
10: 78,635,951 (GRCm39) |
Y339H |
probably damaging |
Het |
| Slc39a8 |
A |
G |
3: 135,532,446 (GRCm39) |
N72D |
probably benign |
Het |
| Slf1 |
A |
G |
13: 77,231,568 (GRCm39) |
S604P |
probably damaging |
Het |
| Slfn4 |
C |
T |
11: 83,079,819 (GRCm39) |
T110M |
probably benign |
Het |
| Tnpo1 |
T |
C |
13: 99,015,220 (GRCm39) |
T116A |
probably damaging |
Het |
| Tor1b |
T |
C |
2: 30,845,893 (GRCm39) |
I190T |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,800,138 (GRCm39) |
E357* |
probably null |
Het |
| Tubg2 |
G |
T |
11: 101,047,699 (GRCm39) |
E95* |
probably null |
Het |
| Ubap2 |
A |
G |
4: 41,209,351 (GRCm39) |
|
probably null |
Het |
| Ube2i |
T |
C |
17: 25,487,538 (GRCm39) |
D67G |
possibly damaging |
Het |
| Ubxn11 |
A |
G |
4: 133,852,203 (GRCm39) |
E50G |
probably damaging |
Het |
| Wnk1 |
A |
G |
6: 119,929,779 (GRCm39) |
V1246A |
probably damaging |
Het |
| Zcchc7 |
A |
G |
4: 44,929,124 (GRCm39) |
T38A |
possibly damaging |
Het |
|
| Other mutations in Zfp236 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Zfp236
|
APN |
18 |
82,686,815 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01760:Zfp236
|
APN |
18 |
82,639,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01923:Zfp236
|
APN |
18 |
82,700,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01934:Zfp236
|
APN |
18 |
82,651,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01949:Zfp236
|
APN |
18 |
82,642,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02063:Zfp236
|
APN |
18 |
82,676,276 (GRCm39) |
missense |
probably benign |
|
|
IGL02496:Zfp236
|
APN |
18 |
82,648,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02513:Zfp236
|
APN |
18 |
82,648,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Zfp236
|
APN |
18 |
82,676,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL02880:Zfp236
|
APN |
18 |
82,642,584 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL03156:Zfp236
|
APN |
18 |
82,698,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Zfp236
|
APN |
18 |
82,648,733 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0047:Zfp236
|
UTSW |
18 |
82,698,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Zfp236
|
UTSW |
18 |
82,657,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0194:Zfp236
|
UTSW |
18 |
82,675,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0207:Zfp236
|
UTSW |
18 |
82,658,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Zfp236
|
UTSW |
18 |
82,648,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0302:Zfp236
|
UTSW |
18 |
82,676,213 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0730:Zfp236
|
UTSW |
18 |
82,658,369 (GRCm39) |
splice site |
probably benign |
|
|
R0755:Zfp236
|
UTSW |
18 |
82,638,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1202:Zfp236
|
UTSW |
18 |
82,646,291 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1550:Zfp236
|
UTSW |
18 |
82,692,549 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1785:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1786:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2042:Zfp236
|
UTSW |
18 |
82,651,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2133:Zfp236
|
UTSW |
18 |
82,639,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2247:Zfp236
|
UTSW |
18 |
82,622,423 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2484:Zfp236
|
UTSW |
18 |
82,686,762 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3715:Zfp236
|
UTSW |
18 |
82,651,095 (GRCm39) |
splice site |
probably benign |
|
|
R4003:Zfp236
|
UTSW |
18 |
82,698,870 (GRCm39) |
nonsense |
probably null |
|
|
R4031:Zfp236
|
UTSW |
18 |
82,642,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4482:Zfp236
|
UTSW |
18 |
82,662,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4492:Zfp236
|
UTSW |
18 |
82,648,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4502:Zfp236
|
UTSW |
18 |
82,655,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4561:Zfp236
|
UTSW |
18 |
82,638,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp236
|
UTSW |
18 |
82,615,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Zfp236
|
UTSW |
18 |
82,627,543 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5064:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5084:Zfp236
|
UTSW |
18 |
82,627,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5090:Zfp236
|
UTSW |
18 |
82,637,006 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5191:Zfp236
|
UTSW |
18 |
82,639,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5264:Zfp236
|
UTSW |
18 |
82,676,198 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5264:Zfp236
|
UTSW |
18 |
82,648,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5339:Zfp236
|
UTSW |
18 |
82,642,491 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Zfp236
|
UTSW |
18 |
82,615,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5445:Zfp236
|
UTSW |
18 |
82,700,281 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5513:Zfp236
|
UTSW |
18 |
82,676,147 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5527:Zfp236
|
UTSW |
18 |
82,676,159 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5628:Zfp236
|
UTSW |
18 |
82,675,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5758:Zfp236
|
UTSW |
18 |
82,689,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Zfp236
|
UTSW |
18 |
82,658,276 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6137:Zfp236
|
UTSW |
18 |
82,689,919 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6193:Zfp236
|
UTSW |
18 |
82,622,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6198:Zfp236
|
UTSW |
18 |
82,675,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Zfp236
|
UTSW |
18 |
82,675,229 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6705:Zfp236
|
UTSW |
18 |
82,651,862 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6948:Zfp236
|
UTSW |
18 |
82,662,187 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6989:Zfp236
|
UTSW |
18 |
82,646,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Zfp236
|
UTSW |
18 |
82,709,701 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7113:Zfp236
|
UTSW |
18 |
82,638,462 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7261:Zfp236
|
UTSW |
18 |
82,627,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7363:Zfp236
|
UTSW |
18 |
82,639,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7447:Zfp236
|
UTSW |
18 |
82,651,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7564:Zfp236
|
UTSW |
18 |
82,662,366 (GRCm39) |
nonsense |
probably null |
|
|
R7731:Zfp236
|
UTSW |
18 |
82,698,798 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7857:Zfp236
|
UTSW |
18 |
82,686,726 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Zfp236
|
UTSW |
18 |
82,692,481 (GRCm39) |
nonsense |
probably null |
|
|
R7904:Zfp236
|
UTSW |
18 |
82,627,507 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7948:Zfp236
|
UTSW |
18 |
82,642,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp236
|
UTSW |
18 |
82,657,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Zfp236
|
UTSW |
18 |
82,648,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Zfp236
|
UTSW |
18 |
82,658,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Zfp236
|
UTSW |
18 |
82,664,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8878:Zfp236
|
UTSW |
18 |
82,617,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8916:Zfp236
|
UTSW |
18 |
82,664,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Zfp236
|
UTSW |
18 |
82,637,042 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9076:Zfp236
|
UTSW |
18 |
82,638,469 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9243:Zfp236
|
UTSW |
18 |
82,662,050 (GRCm39) |
intron |
probably benign |
|
|
R9594:Zfp236
|
UTSW |
18 |
82,664,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9642:Zfp236
|
UTSW |
18 |
82,622,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Zfp236
|
UTSW |
18 |
82,664,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Zfp236
|
UTSW |
18 |
82,637,008 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCTCTCCAGCAATAACCTTGGTTC -3'
(R):5'- CGCATGTCTTTGACGGAAAGCTTAC -3'
Sequencing Primer
(F):5'- TTCCATGAGGATCAAGGTCAC -3'
(R):5'- CGGAAAGCTTACAGCTTTGC -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation