Incidental Mutation 'R1463:Dnajc13'
| ID |
159235 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnajc13
|
| Ensembl Gene |
ENSMUSG00000032560 |
| Gene Name |
DnaJ heat shock protein family (Hsp40) member C13 |
| Synonyms |
LOC382100, D030002L11Rik, Rme8 |
| MMRRC Submission |
039517-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.934)
|
| Stock # |
R1463 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
104151282-104262930 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 104178940 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 1587
(S1587R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139804
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035170]
[ENSMUST00000186788]
|
| AlphaFold |
D4AFX7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000035170
AA Change: S1582R
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000035170
Gene: ENSMUSG00000032560
AA Change: S1582R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
843 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
Blast:ARM
|
927 |
963 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
976 |
1020 |
1.5e-18 |
PFAM |
|
Blast:ARM
|
1071 |
1110 |
5e-12 |
BLAST |
|
DnaJ
|
1300 |
1358 |
5.69e-18 |
SMART |
|
low complexity region
|
1417 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1829 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1843 |
1884 |
6e-8 |
BLAST |
|
low complexity region
|
1968 |
1984 |
N/A |
INTRINSIC |
|
low complexity region
|
2006 |
2016 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186788
AA Change: S1587R
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000139804
Gene: ENSMUSG00000032560
AA Change: S1587R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
918 |
931 |
N/A |
INTRINSIC |
|
Blast:ARM
|
932 |
968 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
980 |
1025 |
8.1e-14 |
PFAM |
|
Blast:ARM
|
1076 |
1115 |
5e-12 |
BLAST |
|
DnaJ
|
1305 |
1363 |
5.69e-18 |
SMART |
|
low complexity region
|
1422 |
1431 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1848 |
1889 |
6e-8 |
BLAST |
|
low complexity region
|
1973 |
1989 |
N/A |
INTRINSIC |
|
low complexity region
|
2011 |
2021 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191199
|
| Meta Mutation Damage Score |
0.5536 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.6%
|
| Validation Efficiency |
97% (97/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700015F17Rik |
C |
A |
5: 5,452,073 (GRCm38) |
|
probably benign |
Het |
| 4931408C20Rik |
G |
T |
1: 26,682,141 (GRCm38) |
Y1319* |
probably null |
Het |
| Abca5 |
A |
T |
11: 110,314,558 (GRCm38) |
I299N |
probably damaging |
Het |
| Abcc8 |
T |
C |
7: 46,154,512 (GRCm38) |
T413A |
probably benign |
Het |
| Actc1 |
G |
A |
2: 114,049,529 (GRCm38) |
S201F |
probably damaging |
Het |
| Adam30 |
G |
A |
3: 98,162,525 (GRCm38) |
C558Y |
probably damaging |
Het |
| Adcy4 |
T |
A |
14: 55,778,939 (GRCm38) |
I352F |
probably damaging |
Het |
| Adgrl4 |
A |
T |
3: 151,510,596 (GRCm38) |
D472V |
probably damaging |
Het |
| Afap1l2 |
T |
A |
19: 56,930,151 (GRCm38) |
M117L |
probably benign |
Het |
| AI597479 |
T |
C |
1: 43,113,229 (GRCm38) |
V229A |
probably damaging |
Het |
| Ascc1 |
T |
C |
10: 60,062,516 (GRCm38) |
V267A |
probably benign |
Het |
| Asxl3 |
A |
G |
18: 22,516,753 (GRCm38) |
S600G |
possibly damaging |
Het |
| Atg14 |
T |
C |
14: 47,548,994 (GRCm38) |
I268V |
probably benign |
Het |
| Bcas1 |
C |
T |
2: 170,418,664 (GRCm38) |
V32I |
probably benign |
Het |
| Cacna1c |
G |
T |
6: 118,593,994 (GRCm38) |
D2106E |
probably benign |
Het |
| Cacna1i |
A |
G |
15: 80,379,054 (GRCm38) |
H1440R |
possibly damaging |
Het |
| Catsper2 |
G |
A |
2: 121,406,446 (GRCm38) |
T240M |
probably damaging |
Het |
| Cd163 |
A |
G |
6: 124,311,447 (GRCm38) |
E279G |
probably damaging |
Het |
| Cdx2 |
C |
T |
5: 147,306,660 (GRCm38) |
S108N |
probably benign |
Het |
| Cenpf |
A |
T |
1: 189,654,739 (GRCm38) |
N1781K |
probably damaging |
Het |
| Cgref1 |
T |
A |
5: 30,935,994 (GRCm38) |
|
probably benign |
Het |
| Clcn4 |
C |
T |
7: 7,296,764 (GRCm38) |
W22* |
probably null |
Het |
| Cntn2 |
A |
G |
1: 132,521,137 (GRCm38) |
|
probably null |
Het |
| Cntn5 |
C |
T |
9: 9,673,796 (GRCm38) |
|
probably null |
Het |
| Cpeb3 |
A |
G |
19: 37,139,100 (GRCm38) |
M377T |
probably benign |
Het |
| Cryge |
T |
A |
1: 65,048,838 (GRCm38) |
R135* |
probably null |
Het |
| Ctdsp2 |
C |
A |
10: 126,993,921 (GRCm38) |
|
probably benign |
Het |
| Ctsll3 |
G |
A |
13: 60,801,275 (GRCm38) |
|
probably benign |
Het |
| Cuzd1 |
C |
A |
7: 131,316,642 (GRCm38) |
G189C |
probably damaging |
Het |
| Dmbt1 |
T |
A |
7: 131,109,637 (GRCm38) |
|
probably null |
Het |
| Dock4 |
GCTCAGTGTATC |
GC |
12: 40,816,325 (GRCm38) |
|
probably null |
Het |
| Dock6 |
T |
C |
9: 21,831,906 (GRCm38) |
H701R |
probably damaging |
Het |
| Edem3 |
A |
G |
1: 151,807,510 (GRCm38) |
T646A |
possibly damaging |
Het |
| Esrra |
A |
C |
19: 6,912,455 (GRCm38) |
D160E |
probably benign |
Het |
| Fbn2 |
T |
C |
18: 58,010,380 (GRCm38) |
T2868A |
probably benign |
Het |
| Galnt7 |
T |
A |
8: 57,652,858 (GRCm38) |
M41L |
probably benign |
Het |
| Gbf1 |
T |
C |
19: 46,271,545 (GRCm38) |
|
probably benign |
Het |
| Glyat |
A |
G |
19: 12,648,103 (GRCm38) |
N63S |
probably damaging |
Het |
| Gm9376 |
A |
T |
14: 118,267,482 (GRCm38) |
M109L |
probably benign |
Het |
| H2-M10.3 |
A |
G |
17: 36,366,720 (GRCm38) |
V222A |
probably damaging |
Het |
| Ifna12 |
T |
G |
4: 88,602,956 (GRCm38) |
D118A |
possibly damaging |
Het |
| Inpp5j |
T |
C |
11: 3,501,147 (GRCm38) |
M501V |
probably benign |
Het |
| Itpr3 |
C |
T |
17: 27,117,154 (GRCm38) |
|
probably benign |
Het |
| Ivns1abp |
A |
G |
1: 151,361,540 (GRCm38) |
N527S |
probably benign |
Het |
| Kif13a |
T |
C |
13: 46,929,612 (GRCm38) |
T4A |
possibly damaging |
Het |
| Kif3b |
T |
C |
2: 153,330,153 (GRCm38) |
*748Q |
probably null |
Het |
| Klf8 |
C |
T |
X: 153,384,681 (GRCm38) |
Q241* |
probably null |
Het |
| Kras |
A |
T |
6: 145,225,061 (GRCm38) |
|
probably benign |
Het |
| Lamc3 |
C |
A |
2: 31,887,411 (GRCm38) |
T23K |
probably benign |
Het |
| Lrrc74b |
T |
A |
16: 17,559,873 (GRCm38) |
H47L |
probably benign |
Het |
| Ly75 |
A |
G |
2: 60,368,757 (GRCm38) |
|
probably null |
Het |
| Map3k21 |
G |
A |
8: 125,942,137 (GRCm38) |
G821S |
probably benign |
Het |
| Mettl14 |
A |
G |
3: 123,374,073 (GRCm38) |
|
probably benign |
Het |
| Mettl5 |
T |
C |
2: 69,885,246 (GRCm38) |
|
probably benign |
Het |
| Mier3 |
A |
G |
13: 111,711,755 (GRCm38) |
D301G |
probably damaging |
Het |
| Mipep |
T |
C |
14: 60,788,146 (GRCm38) |
|
probably benign |
Het |
| Mmp21 |
T |
C |
7: 133,675,859 (GRCm38) |
|
probably null |
Het |
| Msh4 |
A |
G |
3: 153,857,570 (GRCm38) |
L723P |
probably damaging |
Het |
| Muc5b |
T |
C |
7: 141,859,080 (GRCm38) |
V1921A |
unknown |
Het |
| Myo1e |
G |
A |
9: 70,338,756 (GRCm38) |
E410K |
possibly damaging |
Het |
| Nav2 |
T |
G |
7: 49,535,962 (GRCm38) |
I951S |
probably damaging |
Het |
| Npc1 |
G |
A |
18: 12,191,830 (GRCm38) |
T1202I |
probably damaging |
Het |
| Olfr1441 |
C |
T |
19: 12,422,888 (GRCm38) |
T193I |
probably benign |
Het |
| Olfr218 |
A |
G |
1: 173,203,367 (GRCm38) |
K4E |
probably benign |
Het |
| Olfr324 |
A |
G |
11: 58,598,121 (GRCm38) |
R242G |
probably damaging |
Het |
| Patl2 |
C |
T |
2: 122,123,735 (GRCm38) |
V452M |
probably benign |
Het |
| Pcdh18 |
A |
G |
3: 49,755,405 (GRCm38) |
V487A |
probably damaging |
Het |
| Pdzph1 |
C |
T |
17: 58,932,445 (GRCm38) |
A963T |
probably damaging |
Het |
| Pkd1l1 |
C |
T |
11: 8,916,302 (GRCm38) |
V518M |
probably damaging |
Het |
| Plcd3 |
A |
G |
11: 103,078,373 (GRCm38) |
F256S |
probably damaging |
Het |
| Proc |
T |
C |
18: 32,133,438 (GRCm38) |
D112G |
possibly damaging |
Het |
| Ptges2 |
T |
A |
2: 32,400,862 (GRCm38) |
|
probably null |
Het |
| Pth2r |
A |
T |
1: 65,363,277 (GRCm38) |
R312W |
probably damaging |
Het |
| Rbbp6 |
C |
T |
7: 122,992,453 (GRCm38) |
H546Y |
possibly damaging |
Het |
| Retreg2 |
A |
G |
1: 75,146,520 (GRCm38) |
E364G |
probably damaging |
Het |
| Rxrb |
G |
A |
17: 34,034,160 (GRCm38) |
C185Y |
probably damaging |
Het |
| Sept2 |
T |
A |
1: 93,499,315 (GRCm38) |
N133K |
possibly damaging |
Het |
| Serpina3b |
T |
A |
12: 104,138,710 (GRCm38) |
S382T |
probably benign |
Het |
| Serpinb9e |
T |
C |
13: 33,255,116 (GRCm38) |
F175S |
probably benign |
Het |
| Slc19a2 |
C |
T |
1: 164,257,197 (GRCm38) |
H219Y |
probably damaging |
Het |
| Slfn9 |
A |
T |
11: 82,981,698 (GRCm38) |
D737E |
possibly damaging |
Het |
| Snx31 |
T |
C |
15: 36,539,298 (GRCm38) |
E144G |
probably null |
Het |
| Sp2 |
A |
G |
11: 96,963,456 (GRCm38) |
|
probably benign |
Het |
| Spag9 |
C |
T |
11: 94,116,837 (GRCm38) |
L1117F |
probably damaging |
Het |
| Syndig1l |
A |
T |
12: 84,680,363 (GRCm38) |
|
probably benign |
Het |
| Sypl |
A |
T |
12: 32,974,333 (GRCm38) |
|
probably benign |
Het |
| Tmem169 |
T |
C |
1: 72,300,696 (GRCm38) |
M95T |
probably benign |
Het |
| Tmem206 |
T |
C |
1: 191,328,289 (GRCm38) |
|
probably benign |
Het |
| Tnfrsf17 |
A |
G |
16: 11,315,202 (GRCm38) |
Y48C |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,827,515 (GRCm38) |
|
probably benign |
Het |
| Uap1 |
G |
C |
1: 170,150,383 (GRCm38) |
H366Q |
probably benign |
Het |
| Ulbp1 |
A |
G |
10: 7,446,557 (GRCm38) |
|
probably benign |
Het |
| Urb2 |
T |
C |
8: 124,030,908 (GRCm38) |
V1118A |
probably benign |
Het |
| Usp54 |
T |
C |
14: 20,550,190 (GRCm38) |
N1493S |
probably benign |
Het |
| Vmn1r129 |
C |
A |
7: 21,360,730 (GRCm38) |
V188F |
probably benign |
Het |
| Vmn1r226 |
A |
T |
17: 20,687,732 (GRCm38) |
L75F |
probably benign |
Het |
| Wdr78 |
T |
A |
4: 103,087,418 (GRCm38) |
L245F |
possibly damaging |
Het |
| Wisp1 |
T |
A |
15: 66,919,271 (GRCm38) |
N307K |
possibly damaging |
Het |
| Yes1 |
T |
A |
5: 32,651,702 (GRCm38) |
S137R |
probably benign |
Het |
| Zfp804b |
A |
G |
5: 7,179,372 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Dnajc13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00743:Dnajc13
|
APN |
9 |
104,162,780 (GRCm38) |
missense |
probably benign |
0.15 |
|
IGL00754:Dnajc13
|
APN |
9 |
104,174,498 (GRCm38) |
nonsense |
probably null |
|
|
IGL00914:Dnajc13
|
APN |
9 |
104,212,882 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01014:Dnajc13
|
APN |
9 |
104,203,218 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01077:Dnajc13
|
APN |
9 |
104,231,021 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01137:Dnajc13
|
APN |
9 |
104,160,490 (GRCm38) |
missense |
probably benign |
|
|
IGL01305:Dnajc13
|
APN |
9 |
104,230,637 (GRCm38) |
splice site |
probably null |
|
|
IGL01707:Dnajc13
|
APN |
9 |
104,228,979 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01781:Dnajc13
|
APN |
9 |
104,162,359 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL01868:Dnajc13
|
APN |
9 |
104,162,745 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
IGL01950:Dnajc13
|
APN |
9 |
104,190,432 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02102:Dnajc13
|
APN |
9 |
104,229,009 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
IGL02350:Dnajc13
|
APN |
9 |
104,162,359 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL02357:Dnajc13
|
APN |
9 |
104,162,359 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL02470:Dnajc13
|
APN |
9 |
104,175,747 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02888:Dnajc13
|
APN |
9 |
104,180,062 (GRCm38) |
splice site |
probably benign |
|
|
IGL03079:Dnajc13
|
APN |
9 |
104,212,869 (GRCm38) |
nonsense |
probably null |
|
|
IGL03179:Dnajc13
|
APN |
9 |
104,167,435 (GRCm38) |
missense |
probably benign |
0.42 |
|
IGL03293:Dnajc13
|
APN |
9 |
104,174,426 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
impressario
|
UTSW |
9 |
104,213,886 (GRCm38) |
missense |
probably benign |
0.12 |
|
Kaiser
|
UTSW |
9 |
104,214,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
BB008:Dnajc13
|
UTSW |
9 |
104,218,564 (GRCm38) |
missense |
probably benign |
0.02 |
|
BB018:Dnajc13
|
UTSW |
9 |
104,218,564 (GRCm38) |
missense |
probably benign |
0.02 |
|
PIT4142001:Dnajc13
|
UTSW |
9 |
104,238,473 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0323:Dnajc13
|
UTSW |
9 |
104,156,892 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0361:Dnajc13
|
UTSW |
9 |
104,167,059 (GRCm38) |
missense |
probably benign |
0.18 |
|
R0480:Dnajc13
|
UTSW |
9 |
104,200,509 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0558:Dnajc13
|
UTSW |
9 |
104,201,952 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R0707:Dnajc13
|
UTSW |
9 |
104,172,582 (GRCm38) |
missense |
probably benign |
0.12 |
|
R0831:Dnajc13
|
UTSW |
9 |
104,172,612 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1234:Dnajc13
|
UTSW |
9 |
104,214,157 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R1433:Dnajc13
|
UTSW |
9 |
104,180,121 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,214,167 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,214,167 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1489:Dnajc13
|
UTSW |
9 |
104,231,035 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1575:Dnajc13
|
UTSW |
9 |
104,156,838 (GRCm38) |
missense |
probably benign |
0.29 |
|
R1750:Dnajc13
|
UTSW |
9 |
104,221,477 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1903:Dnajc13
|
UTSW |
9 |
104,228,937 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2066:Dnajc13
|
UTSW |
9 |
104,221,441 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2206:Dnajc13
|
UTSW |
9 |
104,203,518 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3160:Dnajc13
|
UTSW |
9 |
104,219,898 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R3162:Dnajc13
|
UTSW |
9 |
104,219,898 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R4158:Dnajc13
|
UTSW |
9 |
104,190,442 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4460:Dnajc13
|
UTSW |
9 |
104,181,063 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4537:Dnajc13
|
UTSW |
9 |
104,186,805 (GRCm38) |
intron |
probably benign |
|
|
R4538:Dnajc13
|
UTSW |
9 |
104,186,805 (GRCm38) |
intron |
probably benign |
|
|
R4631:Dnajc13
|
UTSW |
9 |
104,190,417 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4662:Dnajc13
|
UTSW |
9 |
104,207,758 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4722:Dnajc13
|
UTSW |
9 |
104,213,818 (GRCm38) |
missense |
probably benign |
|
|
R4731:Dnajc13
|
UTSW |
9 |
104,186,805 (GRCm38) |
intron |
probably benign |
|
|
R4732:Dnajc13
|
UTSW |
9 |
104,186,805 (GRCm38) |
intron |
probably benign |
|
|
R4758:Dnajc13
|
UTSW |
9 |
104,172,574 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Dnajc13
|
UTSW |
9 |
104,175,727 (GRCm38) |
missense |
probably benign |
0.16 |
|
R4802:Dnajc13
|
UTSW |
9 |
104,175,727 (GRCm38) |
missense |
probably benign |
0.16 |
|
R4928:Dnajc13
|
UTSW |
9 |
104,233,638 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4944:Dnajc13
|
UTSW |
9 |
104,167,387 (GRCm38) |
unclassified |
probably benign |
|
|
R4979:Dnajc13
|
UTSW |
9 |
104,186,723 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5177:Dnajc13
|
UTSW |
9 |
104,230,986 (GRCm38) |
missense |
probably benign |
0.39 |
|
R5190:Dnajc13
|
UTSW |
9 |
104,174,525 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5256:Dnajc13
|
UTSW |
9 |
104,203,329 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5452:Dnajc13
|
UTSW |
9 |
104,192,114 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5657:Dnajc13
|
UTSW |
9 |
104,228,537 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5752:Dnajc13
|
UTSW |
9 |
104,192,774 (GRCm38) |
splice site |
probably null |
|
|
R5789:Dnajc13
|
UTSW |
9 |
104,214,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5837:Dnajc13
|
UTSW |
9 |
104,176,666 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R5846:Dnajc13
|
UTSW |
9 |
104,190,385 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5982:Dnajc13
|
UTSW |
9 |
104,184,615 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R6189:Dnajc13
|
UTSW |
9 |
104,213,886 (GRCm38) |
missense |
probably benign |
0.12 |
|
R6355:Dnajc13
|
UTSW |
9 |
104,203,270 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6483:Dnajc13
|
UTSW |
9 |
104,207,804 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6613:Dnajc13
|
UTSW |
9 |
104,213,877 (GRCm38) |
missense |
probably benign |
0.07 |
|
R6962:Dnajc13
|
UTSW |
9 |
104,181,009 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7048:Dnajc13
|
UTSW |
9 |
104,203,414 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7101:Dnajc13
|
UTSW |
9 |
104,165,022 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7304:Dnajc13
|
UTSW |
9 |
104,238,514 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7353:Dnajc13
|
UTSW |
9 |
104,230,031 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7366:Dnajc13
|
UTSW |
9 |
104,184,706 (GRCm38) |
missense |
probably benign |
0.43 |
|
R7528:Dnajc13
|
UTSW |
9 |
104,178,965 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R7635:Dnajc13
|
UTSW |
9 |
104,162,367 (GRCm38) |
missense |
probably benign |
|
|
R7673:Dnajc13
|
UTSW |
9 |
104,233,692 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7856:Dnajc13
|
UTSW |
9 |
104,167,485 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7931:Dnajc13
|
UTSW |
9 |
104,218,564 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7995:Dnajc13
|
UTSW |
9 |
104,174,363 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8319:Dnajc13
|
UTSW |
9 |
104,190,391 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8354:Dnajc13
|
UTSW |
9 |
104,217,728 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8680:Dnajc13
|
UTSW |
9 |
104,180,139 (GRCm38) |
missense |
probably benign |
|
|
R8686:Dnajc13
|
UTSW |
9 |
104,170,805 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8707:Dnajc13
|
UTSW |
9 |
104,192,648 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8847:Dnajc13
|
UTSW |
9 |
104,180,161 (GRCm38) |
nonsense |
probably null |
|
|
R8868:Dnajc13
|
UTSW |
9 |
104,165,788 (GRCm38) |
missense |
probably benign |
0.13 |
|
R8986:Dnajc13
|
UTSW |
9 |
104,180,131 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9139:Dnajc13
|
UTSW |
9 |
104,207,840 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9334:Dnajc13
|
UTSW |
9 |
104,174,460 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9353:Dnajc13
|
UTSW |
9 |
104,190,372 (GRCm38) |
missense |
probably benign |
0.31 |
|
R9470:Dnajc13
|
UTSW |
9 |
104,230,720 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9528:Dnajc13
|
UTSW |
9 |
104,237,705 (GRCm38) |
missense |
probably benign |
|
|
R9578:Dnajc13
|
UTSW |
9 |
104,238,527 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9658:Dnajc13
|
UTSW |
9 |
104,238,529 (GRCm38) |
missense |
probably benign |
0.11 |
|
R9691:Dnajc13
|
UTSW |
9 |
104,165,012 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0017:Dnajc13
|
UTSW |
9 |
104,238,478 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
X0028:Dnajc13
|
UTSW |
9 |
104,165,018 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGTCTTCTTAGCCGAGAGAACAAGC -3'
(R):5'- AACTCAAATGCGCCGGTCTGTG -3'
Sequencing Primer
(F):5'- AGCAATAGGGATTGTCCTGGTC -3'
(R):5'- CTGTGAGGCTGATCTGATACTCC -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation