Incidental Mutation 'R1350:Atp10d'
ID159522
Institutional Source Beutler Lab
Gene Symbol Atp10d
Ensembl Gene ENSMUSG00000046808
Gene NameATPase, class V, type 10D
SynonymsIMAGE:1069176, 9830145H18Rik, D5Buc24e
MMRRC Submission 039415-MU
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.377) question?
Stock #R1350 (G1)
Quality Score225
Status Validated
Chromosome5
Chromosomal Location72203329-72298775 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 72261126 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000143594 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000126664]
Predicted Effect probably benign
Transcript: ENSMUST00000126664
SMART Domains Protein: ENSMUSP00000143594
Gene: ENSMUSG00000046808

DomainStartEndE-ValueType
signal peptide 1 26 N/A INTRINSIC
Pfam:PhoLip_ATPase_N 111 176 1.2e-21 PFAM
Pfam:E1-E2_ATPase 181 450 3e-10 PFAM
low complexity region 523 534 N/A INTRINSIC
low complexity region 684 696 N/A INTRINSIC
Pfam:Cation_ATPase 739 859 3.4e-7 PFAM
Pfam:HAD 754 1114 1.3e-12 PFAM
Pfam:PhoLip_ATPase_C 1131 1376 4.3e-77 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000136350
Coding Region Coverage
  • 1x: 98.9%
  • 3x: 97.9%
  • 10x: 94.9%
  • 20x: 88.1%
Validation Efficiency 95% (57/60)
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ago4 A G 4: 126,507,132 V640A probably benign Het
AI661453 C T 17: 47,467,928 Q860* probably null Het
Axdnd1 A G 1: 156,378,380 probably null Het
Bivm T A 1: 44,126,703 N104K possibly damaging Het
Capn15 A G 17: 25,964,692 S338P probably benign Het
Car9 G T 4: 43,512,439 probably null Het
Col13a1 G A 10: 61,894,069 probably benign Het
Crb2 A G 2: 37,792,069 N821D probably damaging Het
D5Ertd579e T A 5: 36,613,737 I1105F probably damaging Het
Dnaja2 A T 8: 85,540,088 F337I probably damaging Het
Dntt C T 19: 41,037,139 probably benign Het
Dock3 C T 9: 106,914,632 E1381K possibly damaging Het
Fam213b C A 4: 154,898,128 R107L probably damaging Het
Fibp T C 19: 5,461,391 Y96H probably damaging Het
Garnl3 A G 2: 33,052,214 V85A probably damaging Het
Gsdme A T 6: 50,246,128 probably null Het
Gucy2c A T 6: 136,743,914 probably null Het
Hectd1 A G 12: 51,762,434 V1748A probably benign Het
Hepacam2 G A 6: 3,467,530 Q384* probably null Het
Itga10 T A 3: 96,657,477 M961K probably benign Het
Kcnk1 C T 8: 126,025,228 T191I probably benign Het
Khdrbs1 G A 4: 129,720,752 P336L probably benign Het
Klhdc2 T A 12: 69,305,710 probably null Het
Lipc T C 9: 70,798,367 H478R probably benign Het
Lrp12 A T 15: 39,878,250 C356* probably null Het
Nf1 T A 11: 79,412,687 C397S probably damaging Het
Nox3 A G 17: 3,650,121 F439S probably damaging Het
Olfr1121 T A 2: 87,372,357 V275E probably benign Het
Olfr1271 A T 2: 90,266,346 L28Q probably damaging Het
Olfr401 T C 11: 74,122,213 L308P possibly damaging Het
Olfr46 T C 7: 140,610,709 V181A probably damaging Het
Olfr64 A G 7: 103,893,730 W2R probably benign Het
Olfr847 T G 9: 19,375,414 S156R possibly damaging Het
Olfr884 G A 9: 38,047,815 V198I probably benign Het
Pcif1 T C 2: 164,886,767 F288L probably damaging Het
Skint7 G T 4: 111,980,324 A100S possibly damaging Het
Ssu2 A T 6: 112,374,846 L306* probably null Het
Tasp1 T C 2: 140,057,421 E4G probably damaging Het
Tfb1m A T 17: 3,545,680 D99E probably benign Het
Ube3b A G 5: 114,406,137 probably null Het
Uox A G 3: 146,624,575 D162G probably damaging Het
Usp18 A G 6: 121,262,692 T249A possibly damaging Het
Vmn1r202 T C 13: 22,501,716 N177S probably benign Het
Vwa2 T A 19: 56,909,126 M621K probably damaging Het
Wdfy3 C A 5: 101,898,552 D1797Y probably damaging Het
Wisp3 C T 10: 39,158,306 C100Y probably damaging Het
Ylpm1 A T 12: 85,014,082 probably benign Het
Zbtb9 G A 17: 26,974,406 V262I probably benign Het
Other mutations in Atp10d
AlleleSourceChrCoordTypePredicted EffectPPH Score
R3500:Atp10d UTSW 5 72245723 missense probably damaging 1.00
R3522:Atp10d UTSW 5 72239157 missense probably benign 0.01
R3833:Atp10d UTSW 5 72239225 missense possibly damaging 0.95
R4376:Atp10d UTSW 5 72296975 missense probably damaging 1.00
R4377:Atp10d UTSW 5 72296975 missense probably damaging 1.00
R4755:Atp10d UTSW 5 72246166 missense probably benign 0.04
R4828:Atp10d UTSW 5 72239118 missense probably benign 0.18
R5224:Atp10d UTSW 5 72269326 missense probably benign 0.03
R5289:Atp10d UTSW 5 72255123 missense probably benign 0.27
R5636:Atp10d UTSW 5 72288219 missense probably damaging 1.00
R5640:Atp10d UTSW 5 72247209 missense probably damaging 1.00
R5653:Atp10d UTSW 5 72264067 missense probably benign 0.21
R5681:Atp10d UTSW 5 72246946 critical splice donor site probably benign
R5760:Atp10d UTSW 5 72260937 missense probably benign 0.27
Predicted Primers PCR Primer
(F):5'- ACGCTTCACTTAGCTCCGTATTGTAGA -3'
(R):5'- GGCTTTGAGAGCACTAAACACATTAGGA -3'

Sequencing Primer
(F):5'- GTCTCCTCAGGAAACAGACGTG -3'
(R):5'- TAGGACCAAAAACTATGCTAAGTGC -3'
Posted On2014-03-14