Incidental Mutation 'R1398:Robo4'
| ID |
160239 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Robo4
|
| Ensembl Gene |
ENSMUSG00000032125 |
| Gene Name |
roundabout guidance receptor 4 |
| Synonyms |
Magic roundabout, 1200012D01Rik |
| MMRRC Submission |
039460-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.217)
|
| Stock # |
R1398 (G1)
|
| Quality Score |
187 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
37313198-37325319 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 37319372 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000150722
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000102895]
[ENSMUST00000115046]
[ENSMUST00000115046]
[ENSMUST00000115048]
[ENSMUST00000156972]
[ENSMUST00000214185]
|
| AlphaFold |
Q8C310 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000102895
|
| SMART Domains |
Protein: ENSMUSP00000099959
Gene: ENSMUSG00000032125
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
37 |
N/A |
INTRINSIC |
|
IG
|
48 |
144 |
2.51e0 |
SMART |
|
IGc2
|
160 |
225 |
6.86e-11 |
SMART |
|
FN3
|
263 |
343 |
2.05e0 |
SMART |
|
FN3
|
358 |
440 |
1.27e-3 |
SMART |
|
low complexity region
|
488 |
494 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
562 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
733 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
799 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
866 |
N/A |
INTRINSIC |
|
low complexity region
|
871 |
880 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000115046
|
| SMART Domains |
Protein: ENSMUSP00000110698
Gene: ENSMUSG00000032125
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
37 |
N/A |
INTRINSIC |
|
IG
|
48 |
144 |
2.51e0 |
SMART |
|
IGc2
|
160 |
225 |
6.86e-11 |
SMART |
|
FN3
|
263 |
343 |
2.05e0 |
SMART |
|
FN3
|
358 |
440 |
1.27e-3 |
SMART |
|
low complexity region
|
484 |
500 |
N/A |
INTRINSIC |
|
low complexity region
|
540 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
807 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
834 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
925 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
939 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000115046
|
| SMART Domains |
Protein: ENSMUSP00000110698
Gene: ENSMUSG00000032125
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
37 |
N/A |
INTRINSIC |
|
IG
|
48 |
144 |
2.51e0 |
SMART |
|
IGc2
|
160 |
225 |
6.86e-11 |
SMART |
|
FN3
|
263 |
343 |
2.05e0 |
SMART |
|
FN3
|
358 |
440 |
1.27e-3 |
SMART |
|
low complexity region
|
484 |
500 |
N/A |
INTRINSIC |
|
low complexity region
|
540 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
807 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
834 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
925 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
939 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000115048
|
| SMART Domains |
Protein: ENSMUSP00000110700
Gene: ENSMUSG00000032125
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
37 |
N/A |
INTRINSIC |
|
IG
|
48 |
144 |
2.51e0 |
SMART |
|
IGc2
|
160 |
225 |
6.86e-11 |
SMART |
|
FN3
|
263 |
343 |
2.05e0 |
SMART |
|
FN3
|
358 |
440 |
1.27e-3 |
SMART |
|
low complexity region
|
488 |
494 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
562 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
769 |
N/A |
INTRINSIC |
|
low complexity region
|
782 |
806 |
N/A |
INTRINSIC |
|
low complexity region
|
862 |
873 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
887 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156972
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000214185
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215777
|
| Meta Mutation Damage Score |
0.9495 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.6%
- 20x: 90.7%
|
| Validation Efficiency |
96% (75/78) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a reporter/null allele display enhanced VEGF-induced endothelial migration, tube formation and vascular permeability, and show increased pathologic angiogenesis and vascular leak in models of oxygen-induced retinopathy and choroidal neovascularization. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca17 |
T |
C |
17: 24,547,511 (GRCm39) |
K288E |
probably damaging |
Het |
| Aldh3a2 |
T |
C |
11: 61,147,562 (GRCm39) |
|
probably null |
Het |
| Anks1b |
A |
G |
10: 89,885,891 (GRCm39) |
T196A |
probably damaging |
Het |
| Anks6 |
T |
A |
4: 47,044,926 (GRCm39) |
T327S |
possibly damaging |
Het |
| Bdh2 |
T |
C |
3: 135,001,057 (GRCm39) |
|
probably benign |
Het |
| C4b |
T |
A |
17: 34,949,693 (GRCm39) |
|
probably benign |
Het |
| Cacna2d1 |
G |
A |
5: 16,562,764 (GRCm39) |
V847I |
possibly damaging |
Het |
| Cadps |
G |
T |
14: 12,449,822 (GRCm38) |
T1129K |
probably damaging |
Het |
| Cdc45 |
A |
G |
16: 18,600,721 (GRCm39) |
|
probably benign |
Het |
| Cep63 |
A |
T |
9: 102,480,285 (GRCm39) |
|
probably benign |
Het |
| Chil4 |
T |
A |
3: 106,126,825 (GRCm39) |
|
probably null |
Het |
| Cnot11 |
A |
G |
1: 39,584,261 (GRCm39) |
R478G |
probably damaging |
Het |
| Cyp2c67 |
A |
G |
19: 39,627,069 (GRCm39) |
S254P |
probably damaging |
Het |
| Dnah11 |
T |
A |
12: 118,020,841 (GRCm39) |
K87* |
probably null |
Het |
| Dpy19l2 |
T |
A |
9: 24,492,559 (GRCm39) |
|
probably benign |
Het |
| Dsc1 |
A |
T |
18: 20,221,393 (GRCm39) |
I694N |
probably damaging |
Het |
| Ehd4 |
A |
T |
2: 119,958,081 (GRCm39) |
I168K |
probably benign |
Het |
| Eif4e |
A |
T |
3: 138,252,136 (GRCm39) |
N25Y |
probably damaging |
Het |
| Elapor2 |
A |
G |
5: 9,430,297 (GRCm39) |
Y69C |
probably damaging |
Het |
| Eme2 |
G |
A |
17: 25,111,892 (GRCm39) |
S263F |
probably damaging |
Het |
| Fgfrl1 |
T |
A |
5: 108,854,147 (GRCm39) |
|
probably benign |
Het |
| Fhip2a |
T |
A |
19: 57,361,358 (GRCm39) |
|
probably benign |
Het |
| Gm3159 |
T |
A |
14: 4,398,586 (GRCm38) |
Y92* |
probably null |
Het |
| Gm4922 |
T |
A |
10: 18,659,496 (GRCm39) |
S409C |
possibly damaging |
Het |
| Gmcl1 |
G |
A |
6: 86,691,244 (GRCm39) |
|
probably benign |
Het |
| Grsf1 |
A |
G |
5: 88,813,706 (GRCm39) |
Y231H |
probably benign |
Het |
| Heatr4 |
T |
A |
12: 84,014,395 (GRCm39) |
H614L |
possibly damaging |
Het |
| Hoxa13 |
C |
G |
6: 52,260,647 (GRCm38) |
|
probably benign |
Het |
| Hoxa13 |
G |
C |
6: 52,260,648 (GRCm38) |
|
probably benign |
Het |
| Isg20l2 |
C |
A |
3: 87,846,061 (GRCm39) |
L325I |
probably benign |
Het |
| Kalrn |
A |
G |
16: 34,033,190 (GRCm39) |
Y879H |
probably damaging |
Het |
| Kcnk10 |
C |
A |
12: 98,402,485 (GRCm39) |
W318L |
probably damaging |
Het |
| Kctd1 |
T |
C |
18: 15,195,654 (GRCm39) |
E323G |
possibly damaging |
Het |
| Kif4 |
G |
T |
X: 99,732,703 (GRCm39) |
A492S |
probably benign |
Het |
| Krtap4-1 |
T |
C |
11: 99,518,558 (GRCm39) |
T151A |
unknown |
Het |
| Ldlr |
A |
T |
9: 21,650,838 (GRCm39) |
Q449L |
probably benign |
Het |
| Lepr |
T |
A |
4: 101,649,216 (GRCm39) |
D872E |
probably damaging |
Het |
| Lgals12 |
C |
T |
19: 7,581,322 (GRCm39) |
|
probably benign |
Het |
| Lrig3 |
C |
T |
10: 125,838,957 (GRCm39) |
P488L |
probably benign |
Het |
| Lrrc4b |
A |
C |
7: 44,111,876 (GRCm39) |
I583L |
probably benign |
Het |
| Lyst |
T |
C |
13: 13,915,121 (GRCm39) |
S3272P |
possibly damaging |
Het |
| Marchf2 |
T |
C |
17: 33,915,096 (GRCm39) |
H166R |
probably damaging |
Het |
| Mtbp |
C |
A |
15: 55,440,933 (GRCm39) |
Y373* |
probably null |
Het |
| Myh2 |
C |
T |
11: 67,076,113 (GRCm39) |
H767Y |
probably benign |
Het |
| Ncam1 |
G |
A |
9: 49,428,889 (GRCm39) |
|
probably benign |
Het |
| Neb |
T |
A |
2: 52,179,658 (GRCm39) |
N1282Y |
probably damaging |
Het |
| Nectin3 |
A |
G |
16: 46,269,119 (GRCm39) |
Y428H |
possibly damaging |
Het |
| Nrros |
A |
T |
16: 31,961,962 (GRCm39) |
I649N |
probably damaging |
Het |
| Nvl |
A |
T |
1: 180,924,691 (GRCm39) |
|
probably benign |
Het |
| Or5p70 |
T |
A |
7: 107,994,708 (GRCm39) |
V127E |
probably damaging |
Het |
| Pms1 |
A |
T |
1: 53,246,435 (GRCm39) |
V368E |
possibly damaging |
Het |
| Polq |
T |
A |
16: 36,882,857 (GRCm39) |
S1674T |
possibly damaging |
Het |
| Ppp1r21 |
T |
C |
17: 88,850,307 (GRCm39) |
V31A |
probably damaging |
Het |
| Rev3l |
T |
A |
10: 39,697,579 (GRCm39) |
V692E |
probably benign |
Het |
| Rps6kc1 |
T |
C |
1: 190,532,212 (GRCm39) |
I597V |
probably damaging |
Het |
| Rtel1 |
T |
A |
2: 180,977,658 (GRCm39) |
|
probably null |
Het |
| Scn9a |
A |
G |
2: 66,314,930 (GRCm39) |
M1587T |
probably benign |
Het |
| Sec31b |
T |
A |
19: 44,512,104 (GRCm39) |
I597F |
probably benign |
Het |
| Skint5 |
T |
C |
4: 113,636,268 (GRCm39) |
N650S |
unknown |
Het |
| Slc22a28 |
G |
T |
19: 8,107,566 (GRCm39) |
S167* |
probably null |
Het |
| Slfn1 |
T |
A |
11: 83,011,968 (GRCm39) |
M28K |
probably damaging |
Het |
| Smc6 |
T |
C |
12: 11,321,880 (GRCm39) |
|
probably benign |
Het |
| Sox8 |
T |
C |
17: 25,786,857 (GRCm39) |
H282R |
probably benign |
Het |
| Spata31e2 |
G |
T |
1: 26,724,422 (GRCm39) |
Q253K |
possibly damaging |
Het |
| Syngr3 |
C |
A |
17: 24,905,414 (GRCm39) |
V161L |
probably benign |
Het |
| Trak1 |
C |
T |
9: 121,283,425 (GRCm39) |
S397F |
probably damaging |
Het |
| Uso1 |
C |
T |
5: 92,329,327 (GRCm39) |
A405V |
probably benign |
Het |
| Uvrag |
G |
T |
7: 98,715,027 (GRCm39) |
Y190* |
probably null |
Het |
| Vps13d |
A |
T |
4: 144,826,553 (GRCm39) |
L1726Q |
probably null |
Het |
| Vwf |
A |
T |
6: 125,580,420 (GRCm39) |
Q556L |
probably benign |
Het |
| Wdr70 |
T |
A |
15: 8,065,325 (GRCm39) |
M246L |
probably benign |
Het |
| Yipf3 |
T |
C |
17: 46,562,372 (GRCm39) |
F285S |
probably damaging |
Het |
| Zdhhc13 |
G |
A |
7: 48,476,621 (GRCm39) |
G579R |
probably damaging |
Het |
| Zdhhc18 |
G |
C |
4: 133,354,608 (GRCm39) |
F125L |
probably benign |
Het |
|
| Other mutations in Robo4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Robo4
|
APN |
9 |
37,322,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00392:Robo4
|
APN |
9 |
37,319,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00491:Robo4
|
APN |
9 |
37,317,231 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
IGL00792:Robo4
|
APN |
9 |
37,319,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Robo4
|
APN |
9 |
37,317,296 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01287:Robo4
|
APN |
9 |
37,324,336 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL02289:Robo4
|
APN |
9 |
37,319,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02486:Robo4
|
APN |
9 |
37,319,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Robo4
|
APN |
9 |
37,324,678 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02898:Robo4
|
APN |
9 |
37,319,472 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02965:Robo4
|
APN |
9 |
37,321,765 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL03071:Robo4
|
APN |
9 |
37,315,580 (GRCm39) |
splice site |
probably benign |
|
|
IGL03102:Robo4
|
APN |
9 |
37,315,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Robo4
|
UTSW |
9 |
37,317,106 (GRCm39) |
intron |
probably benign |
|
|
PIT4305001:Robo4
|
UTSW |
9 |
37,322,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0056:Robo4
|
UTSW |
9 |
37,315,773 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0068:Robo4
|
UTSW |
9 |
37,315,773 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0233:Robo4
|
UTSW |
9 |
37,313,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0233:Robo4
|
UTSW |
9 |
37,313,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0416:Robo4
|
UTSW |
9 |
37,316,062 (GRCm39) |
splice site |
probably benign |
|
|
R1005:Robo4
|
UTSW |
9 |
37,319,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1174:Robo4
|
UTSW |
9 |
37,324,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1183:Robo4
|
UTSW |
9 |
37,319,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1254:Robo4
|
UTSW |
9 |
37,322,136 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1505:Robo4
|
UTSW |
9 |
37,314,523 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1701:Robo4
|
UTSW |
9 |
37,314,739 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1834:Robo4
|
UTSW |
9 |
37,324,355 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1899:Robo4
|
UTSW |
9 |
37,315,366 (GRCm39) |
splice site |
probably benign |
|
|
R2203:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R2204:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R2351:Robo4
|
UTSW |
9 |
37,322,956 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2448:Robo4
|
UTSW |
9 |
37,313,958 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R2847:Robo4
|
UTSW |
9 |
37,315,772 (GRCm39) |
nonsense |
probably null |
|
|
R2851:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R2852:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R2877:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R3123:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R3124:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R3125:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R3805:Robo4
|
UTSW |
9 |
37,315,734 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3806:Robo4
|
UTSW |
9 |
37,315,734 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3892:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R3905:Robo4
|
UTSW |
9 |
37,314,801 (GRCm39) |
nonsense |
probably null |
|
|
R3938:Robo4
|
UTSW |
9 |
37,313,313 (GRCm39) |
start gained |
probably benign |
|
|
R4261:Robo4
|
UTSW |
9 |
37,316,877 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4434:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R4435:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R4561:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R4562:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R4568:Robo4
|
UTSW |
9 |
37,316,118 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R4695:Robo4
|
UTSW |
9 |
37,314,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4921:Robo4
|
UTSW |
9 |
37,313,856 (GRCm39) |
missense |
probably benign |
|
|
R5000:Robo4
|
UTSW |
9 |
37,319,664 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5056:Robo4
|
UTSW |
9 |
37,316,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5125:Robo4
|
UTSW |
9 |
37,319,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5178:Robo4
|
UTSW |
9 |
37,319,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5278:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5279:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5285:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5347:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5348:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5361:Robo4
|
UTSW |
9 |
37,324,674 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5403:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5404:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5488:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5489:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5490:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5494:Robo4
|
UTSW |
9 |
37,322,786 (GRCm39) |
frame shift |
probably null |
|
|
R5629:Robo4
|
UTSW |
9 |
37,319,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5736:Robo4
|
UTSW |
9 |
37,316,093 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5796:Robo4
|
UTSW |
9 |
37,322,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5987:Robo4
|
UTSW |
9 |
37,322,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6178:Robo4
|
UTSW |
9 |
37,316,926 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Robo4
|
UTSW |
9 |
37,314,829 (GRCm39) |
missense |
probably benign |
0.35 |
|
R6365:Robo4
|
UTSW |
9 |
37,322,008 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6528:Robo4
|
UTSW |
9 |
37,315,664 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6887:Robo4
|
UTSW |
9 |
37,313,363 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7196:Robo4
|
UTSW |
9 |
37,314,001 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7408:Robo4
|
UTSW |
9 |
37,322,277 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7419:Robo4
|
UTSW |
9 |
37,314,105 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7486:Robo4
|
UTSW |
9 |
37,316,870 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7707:Robo4
|
UTSW |
9 |
37,324,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7839:Robo4
|
UTSW |
9 |
37,322,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Robo4
|
UTSW |
9 |
37,313,931 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8081:Robo4
|
UTSW |
9 |
37,316,936 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8280:Robo4
|
UTSW |
9 |
37,315,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8526:Robo4
|
UTSW |
9 |
37,314,801 (GRCm39) |
nonsense |
probably null |
|
|
R8547:Robo4
|
UTSW |
9 |
37,315,674 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8735:Robo4
|
UTSW |
9 |
37,319,577 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8836:Robo4
|
UTSW |
9 |
37,317,130 (GRCm39) |
missense |
unknown |
|
|
R8889:Robo4
|
UTSW |
9 |
37,314,601 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9018:Robo4
|
UTSW |
9 |
37,315,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9182:Robo4
|
UTSW |
9 |
37,313,206 (GRCm39) |
start gained |
probably benign |
|
|
R9375:Robo4
|
UTSW |
9 |
37,316,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9621:Robo4
|
UTSW |
9 |
37,317,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTCAGTACCTGTAACAGTCGCTCC -3'
(R):5'- AGCCGTAAAACGTGCTCGTGTC -3'
Sequencing Primer
(F):5'- TCAGAGCTGCACGTCTTGAC -3'
(R):5'- AACGTGCTCGTGTCTGGAAG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation