Incidental Mutation 'R1459:Umodl1'
| ID |
162007 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
039514-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1459 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 31205478 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 662
(V662A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000065470
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066554
AA Change: V691A
PolyPhen 2
Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: V691A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000066981
AA Change: V662A
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: V662A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000114555
AA Change: V691A
PolyPhen 2
Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: V691A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.0%
- 10x: 95.3%
- 20x: 89.5%
|
| Validation Efficiency |
96% (87/91) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933430I17Rik |
C |
T |
4: 62,450,578 (GRCm39) |
R51W |
probably damaging |
Het |
| Abcb1a |
T |
A |
5: 8,752,920 (GRCm39) |
L557Q |
probably damaging |
Het |
| Abcb4 |
T |
C |
5: 8,968,662 (GRCm39) |
F334L |
possibly damaging |
Het |
| Adamts14 |
T |
A |
10: 61,034,583 (GRCm39) |
T1102S |
probably benign |
Het |
| Adamtsl1 |
T |
C |
4: 86,344,102 (GRCm39) |
Y1719H |
probably damaging |
Het |
| Adcyap1 |
T |
C |
17: 93,507,550 (GRCm39) |
|
probably null |
Het |
| Ankrd13c |
T |
A |
3: 157,677,947 (GRCm39) |
L219Q |
probably damaging |
Het |
| Ano3 |
C |
A |
2: 110,711,174 (GRCm39) |
A97S |
probably benign |
Het |
| Apaf1 |
T |
C |
10: 90,898,022 (GRCm39) |
N245S |
probably benign |
Het |
| Apob |
A |
G |
12: 8,056,047 (GRCm39) |
T1510A |
probably benign |
Het |
| Apob |
A |
G |
12: 8,061,937 (GRCm39) |
D3473G |
possibly damaging |
Het |
| Arfgap3 |
G |
A |
15: 83,191,138 (GRCm39) |
T12I |
probably benign |
Het |
| Bend4 |
A |
G |
5: 67,557,418 (GRCm39) |
V466A |
probably damaging |
Het |
| Bend7 |
G |
A |
2: 4,749,239 (GRCm39) |
E119K |
probably damaging |
Het |
| Capn5 |
G |
T |
7: 97,781,049 (GRCm39) |
R243S |
possibly damaging |
Het |
| Cd84 |
A |
G |
1: 171,679,510 (GRCm39) |
I63V |
probably benign |
Het |
| Cd86 |
T |
A |
16: 36,449,350 (GRCm39) |
T16S |
probably benign |
Het |
| Cdc42bpb |
A |
G |
12: 111,262,734 (GRCm39) |
|
probably benign |
Het |
| Cep20 |
G |
A |
16: 14,122,380 (GRCm39) |
T128I |
possibly damaging |
Het |
| Cep95 |
C |
T |
11: 106,708,781 (GRCm39) |
S26L |
probably damaging |
Het |
| Cldn19 |
C |
T |
4: 119,112,810 (GRCm39) |
A14V |
probably damaging |
Het |
| Cluap1 |
T |
A |
16: 3,755,453 (GRCm39) |
M356K |
probably damaging |
Het |
| Coq7 |
C |
T |
7: 118,109,260 (GRCm39) |
G263S |
unknown |
Het |
| Ctnnd2 |
A |
C |
15: 30,847,445 (GRCm39) |
T679P |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,820,750 (GRCm39) |
D528G |
possibly damaging |
Het |
| Dvl1 |
T |
A |
4: 155,938,476 (GRCm39) |
N133K |
probably damaging |
Het |
| Efcab7 |
T |
G |
4: 99,769,744 (GRCm39) |
H550Q |
probably null |
Het |
| Fastkd5 |
C |
T |
2: 130,456,717 (GRCm39) |
M624I |
probably damaging |
Het |
| Fbxo42 |
T |
C |
4: 140,895,073 (GRCm39) |
V12A |
probably benign |
Het |
| Gabarapl1 |
T |
A |
6: 129,515,635 (GRCm39) |
M91K |
possibly damaging |
Het |
| Gas7 |
A |
G |
11: 67,552,902 (GRCm39) |
N154S |
probably damaging |
Het |
| Gm21814 |
T |
A |
6: 149,483,650 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl3 |
G |
A |
14: 30,739,803 (GRCm39) |
R12C |
probably damaging |
Het |
| Golga2 |
T |
G |
2: 32,187,807 (GRCm39) |
|
probably null |
Het |
| Grk3 |
T |
A |
5: 113,062,878 (GRCm39) |
R656S |
probably benign |
Het |
| Gsap |
T |
A |
5: 21,412,236 (GRCm39) |
|
probably benign |
Het |
| H60c |
T |
C |
10: 3,210,240 (GRCm39) |
Q103R |
probably benign |
Het |
| Hnrnpr |
T |
A |
4: 136,056,755 (GRCm39) |
S252T |
probably damaging |
Het |
| Itgb4 |
A |
T |
11: 115,869,937 (GRCm39) |
T40S |
probably benign |
Het |
| Krtap27-1 |
T |
C |
16: 88,468,302 (GRCm39) |
N81D |
probably benign |
Het |
| Lilrb4a |
T |
A |
10: 51,367,683 (GRCm39) |
L75Q |
probably benign |
Het |
| Lrp2 |
T |
A |
2: 69,313,738 (GRCm39) |
D2331V |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,290,821 (GRCm39) |
E3546D |
probably damaging |
Het |
| Lzts2 |
T |
A |
19: 45,009,893 (GRCm39) |
V9E |
probably damaging |
Het |
| Matr3 |
T |
A |
18: 35,717,709 (GRCm39) |
D302E |
probably benign |
Het |
| Mcoln2 |
A |
G |
3: 145,897,979 (GRCm39) |
|
probably null |
Het |
| Metap2 |
T |
C |
10: 93,704,811 (GRCm39) |
D272G |
probably damaging |
Het |
| Mitf |
A |
G |
6: 97,987,428 (GRCm39) |
D337G |
probably damaging |
Het |
| Mrtfb |
T |
C |
16: 13,219,433 (GRCm39) |
V693A |
possibly damaging |
Het |
| Msh2 |
A |
G |
17: 87,985,771 (GRCm39) |
E116G |
probably benign |
Het |
| Nlrp10 |
T |
A |
7: 108,523,555 (GRCm39) |
M642L |
probably benign |
Het |
| Noxa1 |
G |
T |
2: 24,982,558 (GRCm39) |
Q86K |
probably benign |
Het |
| Nrap |
T |
C |
19: 56,372,562 (GRCm39) |
T48A |
probably benign |
Het |
| Nup160 |
T |
A |
2: 90,520,494 (GRCm39) |
H308Q |
probably damaging |
Het |
| Osbpl11 |
T |
C |
16: 33,056,699 (GRCm39) |
L711P |
probably damaging |
Het |
| Osbpl6 |
A |
G |
2: 76,385,409 (GRCm39) |
N281S |
probably benign |
Het |
| Pcnp |
C |
T |
16: 55,844,703 (GRCm39) |
E66K |
possibly damaging |
Het |
| Phf11 |
T |
A |
14: 59,482,227 (GRCm39) |
E175D |
probably damaging |
Het |
| Pik3cg |
A |
G |
12: 32,254,983 (GRCm39) |
Y335H |
probably damaging |
Het |
| Plekhg4 |
T |
C |
8: 106,108,431 (GRCm39) |
L1053S |
probably damaging |
Het |
| Plekhh2 |
G |
T |
17: 84,918,203 (GRCm39) |
E1271* |
probably null |
Het |
| Ppp2r2b |
T |
A |
18: 42,871,055 (GRCm39) |
Y82F |
probably damaging |
Het |
| Prkd3 |
T |
C |
17: 79,278,796 (GRCm39) |
D430G |
probably damaging |
Het |
| Prl7d1 |
C |
T |
13: 27,893,240 (GRCm39) |
D224N |
possibly damaging |
Het |
| Ptpdc1 |
A |
T |
13: 48,740,173 (GRCm39) |
N419K |
possibly damaging |
Het |
| Serinc5 |
T |
A |
13: 92,797,695 (GRCm39) |
|
probably null |
Het |
| Sipa1 |
A |
G |
19: 5,701,692 (GRCm39) |
L981P |
probably damaging |
Het |
| Slc16a7 |
A |
T |
10: 125,066,489 (GRCm39) |
C383* |
probably null |
Het |
| Slc19a1 |
C |
G |
10: 76,878,369 (GRCm39) |
Y301* |
probably null |
Het |
| Slc22a14 |
A |
T |
9: 119,052,827 (GRCm39) |
V14E |
possibly damaging |
Het |
| Slpi |
C |
A |
2: 164,196,837 (GRCm39) |
C95F |
probably damaging |
Het |
| Smurf2 |
G |
A |
11: 106,743,333 (GRCm39) |
H225Y |
possibly damaging |
Het |
| Son |
T |
C |
16: 91,452,230 (GRCm39) |
S326P |
possibly damaging |
Het |
| Sptb |
T |
A |
12: 76,658,657 (GRCm39) |
K1262M |
probably benign |
Het |
| Sugp2 |
T |
A |
8: 70,696,714 (GRCm39) |
|
probably benign |
Het |
| Tatdn2 |
T |
A |
6: 113,687,031 (GRCm39) |
H747Q |
probably damaging |
Het |
| Tcn2 |
C |
A |
11: 3,877,516 (GRCm39) |
R44L |
probably benign |
Het |
| Tenm3 |
G |
A |
8: 48,689,006 (GRCm39) |
R2194C |
probably damaging |
Het |
| Tnks2 |
T |
A |
19: 36,822,931 (GRCm39) |
|
probably benign |
Het |
| Top3a |
A |
T |
11: 60,650,188 (GRCm39) |
I120N |
probably damaging |
Het |
| Ush2a |
T |
C |
1: 188,595,048 (GRCm39) |
S3827P |
probably benign |
Het |
| Vasn |
T |
A |
16: 4,466,473 (GRCm39) |
|
probably null |
Het |
| Vmn2r69 |
A |
T |
7: 85,055,908 (GRCm39) |
C743* |
probably null |
Het |
| Vmn2r79 |
C |
A |
7: 86,687,002 (GRCm39) |
H794Q |
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCACTAAGTTCCAAGCACCCAAGG -3'
(R):5'- GGCACAACCAACATTTCTGGCAAG -3'
Sequencing Primer
(F):5'- TATGGAGGTGCCCAACGTG -3'
(R):5'- CAACATTTCTGGCAAGTCTGACG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation