Incidental Mutation 'R1450:Hfm1'
| ID |
162138 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
039505-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.086)
|
| Stock # |
R1450 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
106840192-106926321 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 106918458 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 35
(F35L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112590
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148686]
[ENSMUST00000200249]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112690
AA Change: F35L
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: F35L
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000117588
AA Change: F35L
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: F35L
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134292
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148686
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200249
AA Change: F35L
PolyPhen 2
Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000142727
Gene: ENSMUSG00000043410
AA Change: F35L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ResIII
|
260 |
410 |
9.9e-7 |
PFAM |
|
Pfam:DEAD
|
281 |
410 |
1.5e-19 |
PFAM |
|
| Meta Mutation Damage Score |
0.0883 |
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.7%
- 10x: 94.0%
- 20x: 84.8%
|
| Validation Efficiency |
96% (73/76) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 69 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700013F07Rik |
T |
A |
3: 108,542,483 (GRCm38) |
|
probably null |
Het |
| Abca13 |
A |
T |
11: 9,430,531 (GRCm38) |
|
probably benign |
Het |
| Adh4 |
C |
T |
3: 138,424,174 (GRCm38) |
P254S |
probably damaging |
Het |
| Amfr |
T |
C |
8: 93,987,747 (GRCm38) |
T223A |
probably benign |
Het |
| Ank2 |
T |
C |
3: 126,957,302 (GRCm38) |
T412A |
possibly damaging |
Het |
| Bag6 |
T |
A |
17: 35,141,958 (GRCm38) |
D422E |
probably benign |
Het |
| Ccdc185 |
T |
G |
1: 182,747,564 (GRCm38) |
Q520P |
possibly damaging |
Het |
| Clock |
G |
A |
5: 76,262,731 (GRCm38) |
Q98* |
probably null |
Het |
| Cngb3 |
A |
T |
4: 19,395,922 (GRCm38) |
|
probably benign |
Het |
| Csmd1 |
T |
G |
8: 15,945,180 (GRCm38) |
|
probably null |
Het |
| Cubn |
A |
G |
2: 13,360,319 (GRCm38) |
L1636P |
probably damaging |
Het |
| Dennd4a |
A |
G |
9: 64,911,665 (GRCm38) |
I1701V |
probably benign |
Het |
| Dgcr2 |
T |
C |
16: 17,856,814 (GRCm38) |
H243R |
possibly damaging |
Het |
| Dimt1 |
A |
G |
13: 106,947,643 (GRCm38) |
N46S |
probably benign |
Het |
| Dnah9 |
T |
C |
11: 65,927,786 (GRCm38) |
Y58C |
probably damaging |
Het |
| Dsg1b |
T |
A |
18: 20,409,184 (GRCm38) |
V916E |
probably damaging |
Het |
| Dst |
T |
C |
1: 34,188,395 (GRCm38) |
S1690P |
probably damaging |
Het |
| Dst |
T |
A |
1: 34,212,259 (GRCm38) |
I2131K |
probably damaging |
Het |
| Epb41l1 |
T |
C |
2: 156,511,825 (GRCm38) |
|
probably benign |
Het |
| Fem1a |
T |
C |
17: 56,257,579 (GRCm38) |
V224A |
probably damaging |
Het |
| Got2 |
C |
T |
8: 95,871,986 (GRCm38) |
E203K |
probably benign |
Het |
| Hcar2 |
A |
T |
5: 123,864,750 (GRCm38) |
I230N |
probably damaging |
Het |
| Herc3 |
A |
T |
6: 58,876,515 (GRCm38) |
K554* |
probably null |
Het |
| Hmcn1 |
A |
G |
1: 150,652,506 (GRCm38) |
|
probably benign |
Het |
| Hoxa13 |
G |
C |
6: 52,260,648 (GRCm38) |
|
probably benign |
Het |
| Hoxa13 |
C |
G |
6: 52,260,647 (GRCm38) |
|
probably benign |
Het |
| Hs2st1 |
C |
T |
3: 144,434,718 (GRCm38) |
|
probably benign |
Het |
| Igfbp5 |
T |
A |
1: 72,873,889 (GRCm38) |
D84V |
probably benign |
Het |
| Ints3 |
C |
A |
3: 90,432,828 (GRCm38) |
L41F |
probably damaging |
Het |
| Ipo5 |
T |
C |
14: 120,944,393 (GRCm38) |
V966A |
probably benign |
Het |
| Kif26a |
C |
T |
12: 112,173,852 (GRCm38) |
T505M |
probably damaging |
Het |
| Kpna2 |
A |
G |
11: 106,997,309 (GRCm38) |
S2P |
probably benign |
Het |
| Lct |
A |
G |
1: 128,307,903 (GRCm38) |
S456P |
probably damaging |
Het |
| Lonrf2 |
G |
A |
1: 38,813,276 (GRCm38) |
P165S |
probably benign |
Het |
| Lrrc7 |
T |
G |
3: 158,187,044 (GRCm38) |
I323L |
possibly damaging |
Het |
| Ly6g |
A |
G |
15: 75,158,633 (GRCm38) |
K77R |
probably benign |
Het |
| Maea |
T |
C |
5: 33,365,800 (GRCm38) |
|
probably null |
Het |
| Marco |
A |
T |
1: 120,476,745 (GRCm38) |
|
probably benign |
Het |
| Mcmbp |
G |
T |
7: 128,715,931 (GRCm38) |
|
probably benign |
Het |
| Mtr |
T |
A |
13: 12,193,733 (GRCm38) |
R1017W |
probably damaging |
Het |
| Myo15 |
T |
A |
11: 60,495,482 (GRCm38) |
I1811N |
probably damaging |
Het |
| Nbeal2 |
G |
A |
9: 110,633,672 (GRCm38) |
|
probably benign |
Het |
| Nlrp10 |
A |
G |
7: 108,925,388 (GRCm38) |
V295A |
probably damaging |
Het |
| Olfr1328 |
T |
C |
4: 118,934,510 (GRCm38) |
T111A |
probably benign |
Het |
| Olfr513 |
A |
T |
7: 108,755,512 (GRCm38) |
I219F |
probably damaging |
Het |
| Olfr616 |
A |
G |
7: 103,564,451 (GRCm38) |
V276A |
probably benign |
Het |
| Pde4b |
A |
T |
4: 102,601,635 (GRCm38) |
Q496L |
probably damaging |
Het |
| Peg12 |
C |
A |
7: 62,463,576 (GRCm38) |
G258* |
probably null |
Het |
| Pigc |
A |
G |
1: 161,971,253 (GRCm38) |
Y268C |
probably benign |
Het |
| Pnisr |
G |
T |
4: 21,874,912 (GRCm38) |
|
probably null |
Het |
| Poteg |
T |
C |
8: 27,447,843 (GRCm38) |
F5S |
probably benign |
Het |
| Prss40 |
T |
A |
1: 34,556,097 (GRCm38) |
I101F |
probably benign |
Het |
| Ptges3l |
T |
A |
11: 101,421,905 (GRCm38) |
D113V |
possibly damaging |
Het |
| Raver2 |
T |
C |
4: 101,136,152 (GRCm38) |
S510P |
possibly damaging |
Het |
| Rgr |
A |
T |
14: 37,044,684 (GRCm38) |
C94* |
probably null |
Het |
| Rp1l1 |
T |
A |
14: 64,028,150 (GRCm38) |
I395N |
probably benign |
Het |
| Sesn3 |
T |
A |
9: 14,316,224 (GRCm38) |
H168Q |
possibly damaging |
Het |
| Soga3 |
A |
T |
10: 29,147,740 (GRCm38) |
N361I |
probably damaging |
Het |
| Sox30 |
C |
A |
11: 46,017,271 (GRCm38) |
P755Q |
probably damaging |
Het |
| Stac3 |
T |
C |
10: 127,504,885 (GRCm38) |
F173S |
probably damaging |
Het |
| Synj2 |
C |
A |
17: 6,027,324 (GRCm38) |
|
probably benign |
Het |
| Tarsl2 |
A |
T |
7: 65,647,496 (GRCm38) |
I120L |
probably benign |
Het |
| Tas2r124 |
A |
G |
6: 132,755,056 (GRCm38) |
I109M |
probably damaging |
Het |
| Tm4sf19 |
A |
T |
16: 32,407,963 (GRCm38) |
H190L |
probably damaging |
Het |
| Tmem143 |
T |
G |
7: 45,907,108 (GRCm38) |
V179G |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,468,028 (GRCm38) |
F1187S |
probably damaging |
Het |
| Ubtfl1 |
A |
G |
9: 18,409,913 (GRCm38) |
R246G |
possibly damaging |
Het |
| Zdhhc5 |
A |
G |
2: 84,702,389 (GRCm38) |
F57S |
probably damaging |
Het |
| Zfp40 |
A |
T |
17: 23,175,258 (GRCm38) |
M717K |
probably benign |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
106,902,130 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
106,917,606 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
106,917,379 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
106,904,793 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
106,911,544 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
106,904,267 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
106,873,928 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
106,901,761 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
106,895,287 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
106,878,662 (GRCm38) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
106,878,823 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
106,874,252 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
106,895,934 (GRCm38) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
106,911,575 (GRCm38) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
106,856,929 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
106,917,478 (GRCm38) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
106,917,601 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
106,898,256 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
106,878,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
106,904,218 (GRCm38) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
106,911,411 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
106,874,901 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
106,872,353 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1529:Hfm1
|
UTSW |
5 |
106,853,123 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
106,893,523 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
106,896,003 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
106,880,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
106,880,360 (GRCm38) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,847,676 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
106,901,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
106,896,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,847,653 (GRCm38) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
106,872,416 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
106,874,282 (GRCm38) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
106,872,330 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
106,892,839 (GRCm38) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
106,904,797 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
106,886,508 (GRCm38) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
106,874,890 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
106,874,221 (GRCm38) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,847,667 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4745:Hfm1
|
UTSW |
5 |
106,901,843 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R4747:Hfm1
|
UTSW |
5 |
106,917,523 (GRCm38) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,842,539 (GRCm38) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
106,854,740 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
106,892,751 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
106,874,213 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R5093:Hfm1
|
UTSW |
5 |
106,901,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5399:Hfm1
|
UTSW |
5 |
106,917,562 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
106,902,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5436:Hfm1
|
UTSW |
5 |
106,892,772 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R5459:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,847,662 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
106,911,439 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
106,911,453 (GRCm38) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
106,878,589 (GRCm38) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
106,874,917 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
106,898,643 (GRCm38) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
106,886,553 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,841,638 (GRCm38) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,847,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,847,687 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
106,895,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
106,878,815 (GRCm38) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
106,917,374 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,850,410 (GRCm38) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
106,880,477 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7058:Hfm1
|
UTSW |
5 |
106,911,440 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7189:Hfm1
|
UTSW |
5 |
106,901,703 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
106,904,331 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
106,895,218 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
106,917,466 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
106,898,475 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
106,889,925 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
106,881,861 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
106,881,791 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
106,898,553 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
106,896,033 (GRCm38) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
106,881,818 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
106,898,505 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
106,917,573 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,841,745 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
106,893,468 (GRCm38) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
106,874,900 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
106,874,072 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9649:Hfm1
|
UTSW |
5 |
106,918,463 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R9743:Hfm1
|
UTSW |
5 |
106,874,259 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
106,874,030 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
106,917,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
106,871,820 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCACTGACTACACTTCAGAATCTGGCT -3'
(R):5'- CCAGGACAGAGAGTTTGTCTATGGGA -3'
Sequencing Primer
(F):5'- TCAGAATCTGGCTTTCTGAAAAC -3'
(R):5'- ATGCTTGTCTAAGAGTTTGCACC -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation