Incidental Mutation 'R1432:Sned1'
| ID |
162274 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sned1
|
| Ensembl Gene |
ENSMUSG00000047793 |
| Gene Name |
sushi, nidogen and EGF-like domains 1 |
| Synonyms |
D430044C15Rik, 6720455I24Rik, Snep |
| MMRRC Submission |
039487-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.076)
|
| Stock # |
R1432 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
93163563-93228787 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 93209376 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 830
(V830M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000050832
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062202]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000062202
AA Change: V830M
PolyPhen 2
Score 0.895 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000050832
Gene: ENSMUSG00000047793
AA Change: V830M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
24 |
N/A |
INTRINSIC |
|
NIDO
|
103 |
260 |
2.98e-54 |
SMART |
|
EGF
|
271 |
309 |
3.79e-6 |
SMART |
|
EGF_CA
|
311 |
347 |
2.42e-13 |
SMART |
|
EGF
|
352 |
385 |
1.02e-6 |
SMART |
|
EGF_CA
|
387 |
423 |
1.91e-11 |
SMART |
|
EGF
|
432 |
465 |
2.96e-8 |
SMART |
|
EGF
|
471 |
500 |
6.02e0 |
SMART |
|
EGF
|
544 |
577 |
3.54e-6 |
SMART |
|
EGF
|
583 |
616 |
6.06e-5 |
SMART |
|
EGF_CA
|
619 |
655 |
2.33e-6 |
SMART |
|
EGF
|
660 |
693 |
1.77e-6 |
SMART |
|
CCP
|
698 |
751 |
2.5e-11 |
SMART |
|
EGF_CA
|
753 |
789 |
1.66e-11 |
SMART |
|
EGF_CA
|
791 |
827 |
1.38e-8 |
SMART |
|
EGF_CA
|
829 |
865 |
1.92e-7 |
SMART |
|
EGF
|
870 |
903 |
2.35e-2 |
SMART |
|
FN3
|
906 |
991 |
1.7e-4 |
SMART |
|
FN3
|
1005 |
1084 |
1.38e-4 |
SMART |
|
FN3
|
1104 |
1185 |
1.6e-9 |
SMART |
|
EGF
|
1309 |
1342 |
6.16e-6 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000163688
AA Change: V39M
|
| SMART Domains |
Protein: ENSMUSP00000132455
Gene: ENSMUSG00000047793
AA Change: V39M
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_CA
|
1 |
37 |
6.7e-7 |
SMART |
|
EGF_CA
|
39 |
75 |
1.92e-7 |
SMART |
|
EGF
|
80 |
113 |
2.35e-2 |
SMART |
|
FN3
|
116 |
201 |
1.7e-4 |
SMART |
|
FN3
|
215 |
294 |
1.38e-4 |
SMART |
|
FN3
|
314 |
395 |
1.6e-9 |
SMART |
|
EGF
|
487 |
520 |
6.16e-6 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165843
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172289
|
| Meta Mutation Damage Score |
0.1152 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.8%
- 10x: 94.4%
- 20x: 86.1%
|
| Validation Efficiency |
98% (90/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
A |
G |
12: 71,217,361 (GRCm39) |
|
probably null |
Het |
| 9130401M01Rik |
A |
T |
15: 57,892,256 (GRCm39) |
L117Q |
probably damaging |
Het |
| Abcb1b |
A |
G |
5: 8,887,771 (GRCm39) |
K886E |
possibly damaging |
Het |
| Acaa2 |
A |
T |
18: 74,920,198 (GRCm39) |
I9F |
probably damaging |
Het |
| Acap2 |
A |
T |
16: 30,929,901 (GRCm39) |
S386T |
probably damaging |
Het |
| Acsm2 |
A |
T |
7: 119,172,798 (GRCm39) |
I138F |
possibly damaging |
Het |
| Agl |
T |
C |
3: 116,540,342 (GRCm39) |
Y1424C |
probably damaging |
Het |
| Aoc1l1 |
T |
A |
6: 48,952,588 (GRCm39) |
F171Y |
probably damaging |
Het |
| Apc2 |
T |
C |
10: 80,148,183 (GRCm39) |
V1079A |
probably benign |
Het |
| Arhgef6 |
T |
C |
X: 56,383,922 (GRCm39) |
M5V |
probably benign |
Het |
| Armc8 |
C |
T |
9: 99,405,185 (GRCm39) |
|
probably benign |
Het |
| Catsperb |
A |
G |
12: 101,588,476 (GRCm39) |
Y953C |
probably damaging |
Het |
| Cdk13 |
G |
A |
13: 17,893,001 (GRCm39) |
A720V |
probably damaging |
Het |
| Chka |
T |
C |
19: 3,924,809 (GRCm39) |
|
probably benign |
Het |
| Clcc1 |
T |
C |
3: 108,575,418 (GRCm39) |
I165T |
probably benign |
Het |
| Cndp1 |
G |
A |
18: 84,652,777 (GRCm39) |
|
probably benign |
Het |
| Dip2c |
C |
A |
13: 9,603,340 (GRCm39) |
P297Q |
probably damaging |
Het |
| Dnah17 |
A |
T |
11: 117,914,153 (GRCm39) |
W4429R |
probably damaging |
Het |
| Dram2 |
T |
C |
3: 106,478,082 (GRCm39) |
V138A |
possibly damaging |
Het |
| Dus4l |
T |
C |
12: 31,698,770 (GRCm39) |
N78S |
probably benign |
Het |
| Dync1h1 |
G |
A |
12: 110,602,943 (GRCm39) |
E2195K |
probably benign |
Het |
| Ebf1 |
T |
C |
11: 44,895,533 (GRCm39) |
|
probably benign |
Het |
| Epm2a |
T |
A |
10: 11,266,587 (GRCm39) |
Y111N |
probably damaging |
Het |
| Gm773 |
T |
C |
X: 55,247,377 (GRCm39) |
T52A |
probably benign |
Het |
| Gpam |
C |
A |
19: 55,067,693 (GRCm39) |
M483I |
probably damaging |
Het |
| Gpr12 |
T |
C |
5: 146,520,235 (GRCm39) |
H229R |
probably damaging |
Het |
| Gpr149 |
T |
C |
3: 62,438,439 (GRCm39) |
T573A |
probably damaging |
Het |
| Gtf3c3 |
C |
T |
1: 54,456,937 (GRCm39) |
A488T |
probably damaging |
Het |
| Hells |
T |
A |
19: 38,945,628 (GRCm39) |
|
probably null |
Het |
| Herc1 |
T |
A |
9: 66,372,751 (GRCm39) |
N3102K |
probably benign |
Het |
| Herc3 |
A |
T |
6: 58,893,827 (GRCm39) |
T968S |
possibly damaging |
Het |
| Ift88 |
A |
G |
14: 57,674,736 (GRCm39) |
Y69C |
probably benign |
Het |
| Incenp |
G |
A |
19: 9,862,890 (GRCm39) |
T388M |
unknown |
Het |
| Jrkl |
A |
G |
9: 13,245,337 (GRCm39) |
F108S |
probably benign |
Het |
| Khdc1a |
A |
G |
1: 21,420,542 (GRCm39) |
E54G |
possibly damaging |
Het |
| Kif6 |
T |
A |
17: 49,927,728 (GRCm39) |
F58L |
probably damaging |
Het |
| Klk14 |
T |
C |
7: 43,344,342 (GRCm39) |
S218P |
probably damaging |
Het |
| Kmt2e |
T |
C |
5: 23,655,319 (GRCm39) |
M19T |
probably benign |
Het |
| Llgl1 |
G |
T |
11: 60,599,380 (GRCm39) |
G454C |
probably damaging |
Het |
| Lyrm4 |
A |
G |
13: 36,276,898 (GRCm39) |
V33A |
probably benign |
Het |
| Mcam |
C |
T |
9: 44,052,588 (GRCm39) |
R606C |
probably damaging |
Het |
| Mgam |
T |
A |
6: 40,733,301 (GRCm39) |
M692K |
probably damaging |
Het |
| Mmp28 |
C |
T |
11: 83,333,765 (GRCm39) |
R392H |
probably damaging |
Het |
| Mpdz |
G |
A |
4: 81,210,788 (GRCm39) |
T1699M |
probably damaging |
Het |
| Mrps11 |
T |
C |
7: 78,433,310 (GRCm39) |
|
probably benign |
Het |
| Mrtfb |
A |
G |
16: 13,218,866 (GRCm39) |
N504S |
probably benign |
Het |
| Msmo1 |
A |
G |
8: 65,180,650 (GRCm39) |
|
probably benign |
Het |
| Mst1 |
A |
G |
9: 107,961,403 (GRCm39) |
E571G |
probably benign |
Het |
| Myh14 |
T |
C |
7: 44,265,723 (GRCm39) |
E1585G |
probably damaging |
Het |
| Myrfl |
A |
G |
10: 116,613,332 (GRCm39) |
C824R |
probably damaging |
Het |
| Ncapd3 |
C |
T |
9: 26,981,168 (GRCm39) |
|
probably benign |
Het |
| Nlrp4a |
G |
GGTTCTTC |
7: 26,163,622 (GRCm39) |
|
probably null |
Het |
| Nos1 |
C |
T |
5: 118,087,684 (GRCm39) |
|
probably benign |
Het |
| Notch3 |
T |
C |
17: 32,383,198 (GRCm39) |
S47G |
probably benign |
Het |
| Npsr1 |
A |
G |
9: 24,221,371 (GRCm39) |
Y122C |
probably damaging |
Het |
| Or10ak12 |
T |
C |
4: 118,666,435 (GRCm39) |
M209V |
probably benign |
Het |
| Or1j11 |
C |
T |
2: 36,311,655 (GRCm39) |
L82F |
probably damaging |
Het |
| Or5a1 |
G |
T |
19: 12,097,603 (GRCm39) |
R158S |
possibly damaging |
Het |
| Or6c1b |
C |
T |
10: 129,272,807 (GRCm39) |
T42I |
probably damaging |
Het |
| Or6k2 |
T |
A |
1: 173,986,483 (GRCm39) |
V48E |
possibly damaging |
Het |
| Or8b9 |
T |
A |
9: 37,766,548 (GRCm39) |
L145M |
possibly damaging |
Het |
| Otog |
G |
T |
7: 45,950,007 (GRCm39) |
V2490F |
probably damaging |
Het |
| Pibf1 |
T |
C |
14: 99,350,425 (GRCm39) |
V191A |
probably benign |
Het |
| Pip |
A |
G |
6: 41,826,852 (GRCm39) |
M66V |
probably benign |
Het |
| Plxna2 |
C |
T |
1: 194,449,771 (GRCm39) |
R830C |
probably benign |
Het |
| Prkca |
A |
T |
11: 107,830,346 (GRCm39) |
V248E |
probably benign |
Het |
| Prmt7 |
T |
A |
8: 106,963,916 (GRCm39) |
L253* |
probably null |
Het |
| Prrc2a |
G |
T |
17: 35,372,888 (GRCm39) |
|
probably benign |
Het |
| Rasgrf1 |
A |
G |
9: 89,894,853 (GRCm39) |
D1091G |
probably benign |
Het |
| Rbm7 |
C |
A |
9: 48,401,245 (GRCm39) |
G161V |
probably benign |
Het |
| Scn1a |
A |
T |
2: 66,152,773 (GRCm39) |
I736N |
probably damaging |
Het |
| Skint6 |
A |
G |
4: 112,726,721 (GRCm39) |
|
probably benign |
Het |
| Slc22a2 |
C |
T |
17: 12,803,195 (GRCm39) |
H10Y |
possibly damaging |
Het |
| Stam2 |
A |
G |
2: 52,604,821 (GRCm39) |
|
probably benign |
Het |
| Stk40 |
T |
C |
4: 126,030,626 (GRCm39) |
L282P |
probably damaging |
Het |
| Tas2r110 |
A |
G |
6: 132,845,331 (GRCm39) |
N121D |
probably damaging |
Het |
| Tbc1d32 |
A |
G |
10: 55,893,758 (GRCm39) |
Y1272H |
probably damaging |
Het |
| Thoc2l |
T |
C |
5: 104,665,970 (GRCm39) |
F164S |
probably damaging |
Het |
| Tmem131l |
T |
C |
3: 83,836,021 (GRCm39) |
D696G |
probably damaging |
Het |
| Trdmt1 |
T |
C |
2: 13,524,657 (GRCm39) |
Y266C |
probably damaging |
Het |
| Trim5 |
G |
T |
7: 103,928,726 (GRCm39) |
H72N |
probably benign |
Het |
| Trim5 |
A |
C |
7: 103,928,728 (GRCm39) |
L71R |
probably benign |
Het |
| Twf2 |
T |
A |
9: 106,092,012 (GRCm39) |
|
probably benign |
Het |
| Ubap2l |
T |
C |
3: 89,926,635 (GRCm39) |
T580A |
probably benign |
Het |
| Ugt1a10 |
C |
T |
1: 88,143,982 (GRCm39) |
R201C |
probably damaging |
Het |
| Unc5a |
A |
G |
13: 55,152,285 (GRCm39) |
|
probably benign |
Het |
| Vmn2r85 |
T |
C |
10: 130,261,155 (GRCm39) |
N394S |
possibly damaging |
Het |
| Wrn |
A |
T |
8: 33,809,169 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Sned1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00785:Sned1
|
APN |
1 |
93,201,891 (GRCm39) |
splice site |
probably benign |
|
|
IGL00955:Sned1
|
APN |
1 |
93,202,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01367:Sned1
|
APN |
1 |
93,210,936 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02116:Sned1
|
APN |
1 |
93,209,447 (GRCm39) |
nonsense |
probably null |
|
|
IGL02195:Sned1
|
APN |
1 |
93,201,882 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02390:Sned1
|
APN |
1 |
93,189,386 (GRCm39) |
missense |
probably benign |
|
|
IGL02423:Sned1
|
APN |
1 |
93,211,322 (GRCm39) |
missense |
probably benign |
|
|
IGL02451:Sned1
|
APN |
1 |
93,163,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02567:Sned1
|
APN |
1 |
93,202,069 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03184:Sned1
|
APN |
1 |
93,202,390 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03328:Sned1
|
APN |
1 |
93,217,089 (GRCm39) |
missense |
probably benign |
|
|
Bulger
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
farina
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Millet
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
triticale
|
UTSW |
1 |
93,281,654 (GRCm39) |
missense |
|
|
|
R0257:Sned1
|
UTSW |
1 |
93,192,819 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0372:Sned1
|
UTSW |
1 |
93,213,673 (GRCm39) |
splice site |
probably benign |
|
|
R0525:Sned1
|
UTSW |
1 |
93,199,696 (GRCm39) |
splice site |
probably null |
|
|
R0727:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0759:Sned1
|
UTSW |
1 |
93,200,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0965:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0968:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0969:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1006:Sned1
|
UTSW |
1 |
93,184,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1068:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1069:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1070:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1112:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1113:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1114:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1115:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1118:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1119:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1144:Sned1
|
UTSW |
1 |
93,208,298 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1228:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1230:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1231:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1313:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1340:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1382:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1383:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1394:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1395:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1397:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1414:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1430:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1473:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1503:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1563:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1565:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1689:Sned1
|
UTSW |
1 |
93,211,094 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1695:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1734:Sned1
|
UTSW |
1 |
93,187,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1767:Sned1
|
UTSW |
1 |
93,209,376 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1896:Sned1
|
UTSW |
1 |
93,192,769 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1916:Sned1
|
UTSW |
1 |
93,201,884 (GRCm39) |
missense |
probably null |
1.00 |
|
R1945:Sned1
|
UTSW |
1 |
93,198,960 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1972:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1973:Sned1
|
UTSW |
1 |
93,192,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Sned1
|
UTSW |
1 |
93,199,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2153:Sned1
|
UTSW |
1 |
93,202,379 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2273:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2274:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2275:Sned1
|
UTSW |
1 |
93,209,364 (GRCm39) |
splice site |
probably null |
|
|
R2340:Sned1
|
UTSW |
1 |
93,184,174 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3237:Sned1
|
UTSW |
1 |
93,186,725 (GRCm39) |
missense |
probably benign |
0.21 |
|
R3747:Sned1
|
UTSW |
1 |
93,189,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Sned1
|
UTSW |
1 |
93,192,752 (GRCm39) |
splice site |
probably benign |
|
|
R4281:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4282:Sned1
|
UTSW |
1 |
93,213,577 (GRCm39) |
nonsense |
probably null |
|
|
R4356:Sned1
|
UTSW |
1 |
93,193,113 (GRCm39) |
splice site |
probably null |
|
|
R4358:Sned1
|
UTSW |
1 |
93,202,381 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4677:Sned1
|
UTSW |
1 |
93,224,019 (GRCm39) |
unclassified |
probably benign |
|
|
R5291:Sned1
|
UTSW |
1 |
93,223,446 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5340:Sned1
|
UTSW |
1 |
93,210,479 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5542:Sned1
|
UTSW |
1 |
93,199,324 (GRCm39) |
missense |
probably benign |
|
|
R5582:Sned1
|
UTSW |
1 |
93,210,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5874:Sned1
|
UTSW |
1 |
93,193,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6159:Sned1
|
UTSW |
1 |
93,210,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6175:Sned1
|
UTSW |
1 |
93,203,196 (GRCm39) |
splice site |
probably null |
|
|
R6445:Sned1
|
UTSW |
1 |
93,211,318 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6631:Sned1
|
UTSW |
1 |
93,209,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Sned1
|
UTSW |
1 |
93,212,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7035:Sned1
|
UTSW |
1 |
93,189,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7047:Sned1
|
UTSW |
1 |
93,213,540 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7347:Sned1
|
UTSW |
1 |
93,209,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Sned1
|
UTSW |
1 |
93,217,080 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7581:Sned1
|
UTSW |
1 |
93,184,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7679:Sned1
|
UTSW |
1 |
93,163,760 (GRCm39) |
missense |
unknown |
|
|
R7899:Sned1
|
UTSW |
1 |
93,201,804 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8093:Sned1
|
UTSW |
1 |
93,202,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8124:Sned1
|
UTSW |
1 |
93,210,711 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8489:Sned1
|
UTSW |
1 |
93,210,978 (GRCm39) |
nonsense |
probably null |
|
|
R9012:Sned1
|
UTSW |
1 |
93,212,320 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9290:Sned1
|
UTSW |
1 |
93,199,385 (GRCm39) |
nonsense |
probably null |
|
|
R9560:Sned1
|
UTSW |
1 |
93,202,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9775:Sned1
|
UTSW |
1 |
93,199,604 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0025:Sned1
|
UTSW |
1 |
93,189,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sned1
|
UTSW |
1 |
93,186,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Sned1
|
UTSW |
1 |
93,213,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATCCTCTTGCTGGACAAGCTAC -3'
(R):5'- TCCTGAAAAGCCTGACCAAGTGTG -3'
Sequencing Primer
(F):5'- TTGCTGGACAAGCTACTCAGAG -3'
(R):5'- GCCTATCCAGGGACAACAGAG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation