Mutagenetix > Incidental Mutation

Incidental Mutation 'R1484:Nbeal1'

163274

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

039537-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1484 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

60219758-60377487 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 60240098 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Leucine at position 155 (F155L)

Ref Sequence

ENSEMBL: ENSMUSP00000124056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834]

AlphaFold

E9PYP2

Predicted Effect

probably damaging
Transcript: ENSMUST00000035569
AA Change: F155L

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664
AA Change: F155L

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000160834
AA Change: F155L

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: F155L

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Meta Mutation Damage Score

0.0969

Coding Region Coverage

1x: 99.2%
3x: 98.4%
10x: 96.5%
20x: 93.4%

Validation Efficiency

97% (85/88)

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 85 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930584F24Rik	A	T	5: 26,684,776 (GRCm39)		noncoding transcript	Het
Acvr1	A	T	2: 58,369,901 (GRCm39)	V36E	probably damaging	Het
Aldh4a1	A	G	4: 139,370,758 (GRCm39)	I414V	probably benign	Het
Alox5	C	T	6: 116,431,128 (GRCm39)	C100Y	probably damaging	Het
Ano5	T	A	7: 51,216,068 (GRCm39)	D348E	probably damaging	Het
Arhgap30	G	A	1: 171,230,839 (GRCm39)	V199M	probably damaging	Het
Arl13b	T	A	16: 62,626,999 (GRCm39)	Q234L	probably benign	Het
Atxn1	C	A	13: 45,711,052 (GRCm39)	E627*	probably null	Het
Bend3	T	C	10: 43,386,197 (GRCm39)	F197L	probably benign	Het
Brca1	A	T	11: 101,420,638 (GRCm39)	V190E	possibly damaging	Het
Brpf1	T	C	6: 113,292,096 (GRCm39)	W381R	probably damaging	Het
Brwd1	A	C	16: 95,829,491 (GRCm39)		probably null	Het
C1s2	T	C	6: 124,602,604 (GRCm39)	I530V	possibly damaging	Het
C2cd3	C	T	7: 100,089,397 (GRCm39)	R1638W	probably damaging	Het
Capns1	T	A	7: 29,893,511 (GRCm39)		probably benign	Het
Cd109	CATTTATTTATTTATTTATTTATTTATTTATTTAT	CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT	9: 78,619,782 (GRCm39)		probably benign	Het
Cep126	G	A	9: 8,100,554 (GRCm39)	T660I	possibly damaging	Het
Cep295	A	C	9: 15,246,080 (GRCm39)	I744R	probably damaging	Het
Chd3	T	C	11: 69,250,725 (GRCm39)	E668G	probably benign	Het
Chek2	A	G	5: 110,996,553 (GRCm39)	T172A	probably damaging	Het
Col6a4	A	G	9: 105,890,501 (GRCm39)		probably null	Het
Coq3	G	A	4: 21,900,291 (GRCm39)	V173I	probably benign	Het
Cyp4x1	A	T	4: 114,970,098 (GRCm39)	I343N	probably damaging	Het
Dnah7b	T	A	1: 46,176,703 (GRCm39)	D774E	probably benign	Het
Dnai3	T	C	3: 145,802,996 (GRCm39)	D65G	probably benign	Het
Ecm1	G	A	3: 95,643,275 (GRCm39)	R342C	probably damaging	Het
Esrra	T	C	19: 6,890,197 (GRCm39)	Y209C	probably damaging	Het
Gpr149	A	T	3: 62,502,592 (GRCm39)	D421E	probably benign	Het
Gpr15	T	C	16: 58,538,937 (GRCm39)	N51D	probably damaging	Het
Gpr156	T	C	16: 37,812,558 (GRCm39)	V298A	probably damaging	Het
Hmcn2	G	A	2: 31,236,507 (GRCm39)	G350D	probably damaging	Het
Ifih1	A	T	2: 62,440,902 (GRCm39)	N421K	probably benign	Het
Ilvbl	C	A	10: 78,412,564 (GRCm39)	T95K	probably damaging	Het
Itgb4	T	A	11: 115,890,625 (GRCm39)	D1104E	probably benign	Het
Katnip	C	A	7: 125,415,743 (GRCm39)		probably benign	Het
Lipf	A	T	19: 33,942,180 (GRCm39)	M37L	probably benign	Het
Lyst	T	A	13: 13,852,775 (GRCm39)	N2258K	probably benign	Het
Moxd1	A	G	10: 24,099,758 (GRCm39)	Y86C	probably damaging	Het
Muc5ac	T	C	7: 141,367,629 (GRCm39)		probably null	Het
Myo16	G	A	8: 10,610,145 (GRCm39)	R1162H	probably damaging	Het
Myo5c	A	T	9: 75,208,092 (GRCm39)	N1609Y	probably damaging	Het
Nek4	A	T	14: 30,704,290 (GRCm39)	M602L	possibly damaging	Het
Nek9	A	G	12: 85,348,622 (GRCm39)	S971P	probably damaging	Het
Nfya	A	T	17: 48,700,570 (GRCm39)		probably benign	Het
Nrxn3	A	T	12: 89,221,547 (GRCm39)	N442I	probably damaging	Het
Nup42	A	C	5: 24,383,075 (GRCm39)	K200N	probably benign	Het
Or1e26	T	A	11: 73,480,187 (GRCm39)	I126L	possibly damaging	Het
Or4c111	G	A	2: 88,843,713 (GRCm39)	R232*	probably null	Het
Or7g32	G	A	9: 19,389,423 (GRCm39)	T38I	probably damaging	Het
Pcdh15	T	A	10: 74,126,833 (GRCm39)	I304N	probably damaging	Het
Pigo	G	C	4: 43,024,779 (GRCm39)	P107A	probably damaging	Het
Plce1	C	T	19: 38,693,783 (GRCm39)	Q769*	probably null	Het
Plin2	C	T	4: 86,575,481 (GRCm39)	R356H	probably benign	Het
Ppp1r9a	G	T	6: 5,113,712 (GRCm39)	E739*	probably null	Het
Ppp3cc	G	T	14: 70,478,397 (GRCm39)	N268K	probably damaging	Het
Prkag3	T	A	1: 74,779,919 (GRCm39)	D472V	probably damaging	Het
Ptch2	A	T	4: 116,968,046 (GRCm39)	D846V	probably damaging	Het
Rhob	A	T	12: 8,549,388 (GRCm39)	M82K	probably damaging	Het
Rps6kc1	T	A	1: 190,531,672 (GRCm39)	R777W	possibly damaging	Het
Sap130	T	A	18: 31,844,380 (GRCm39)	V850E	probably damaging	Het
Sema3a	T	G	5: 13,523,407 (GRCm39)	N125K	probably damaging	Het
Sema5a	A	G	15: 32,460,431 (GRCm39)	D64G	probably damaging	Het
Sgo2b	T	A	8: 64,384,507 (GRCm39)	D163V	possibly damaging	Het
Slc15a1	A	T	14: 121,728,651 (GRCm39)	Y31*	probably null	Het
Smchd1	A	T	17: 71,685,252 (GRCm39)	M1392K	probably benign	Het
Sobp	T	A	10: 43,036,827 (GRCm39)	N37I	probably damaging	Het
Spock3	G	T	8: 63,673,739 (GRCm39)	C142F	probably damaging	Het
Stx6	A	C	1: 155,053,650 (GRCm39)	S86R	probably benign	Het
Sult2a4	C	A	7: 13,643,726 (GRCm39)	M280I	probably benign	Het
Synm	A	T	7: 67,386,080 (GRCm39)	D527E	probably damaging	Het
Tax1bp1	C	T	6: 52,710,305 (GRCm39)	R195W	probably damaging	Het
Themis2	A	T	4: 132,519,796 (GRCm39)	N76K	possibly damaging	Het
Tmem8b	A	G	4: 43,690,234 (GRCm39)	T890A	probably benign	Het
Traf7	T	A	17: 24,730,785 (GRCm39)	H366L	possibly damaging	Het
Trim30c	A	T	7: 104,032,459 (GRCm39)	V289D	probably benign	Het
Tsr1	T	A	11: 74,792,914 (GRCm39)	D407E	probably damaging	Het
Ubap2	G	T	4: 41,235,593 (GRCm39)	A33E	probably damaging	Het
Unc13d	C	A	11: 115,964,701 (GRCm39)	R255L	possibly damaging	Het
Ush2a	G	T	1: 188,542,534 (GRCm39)	G3367*	probably null	Het
Vmn1r229	T	C	17: 21,034,791 (GRCm39)	L12P	probably damaging	Het
Vmn2r27	C	A	6: 124,177,474 (GRCm39)	G510V	probably damaging	Het
Vps4b	T	C	1: 106,707,712 (GRCm39)	E257G	probably damaging	Het
Vps72	T	C	3: 95,026,462 (GRCm39)	S136P	probably damaging	Het
Wdr36	T	C	18: 32,976,938 (GRCm39)	I181T	possibly damaging	Het
Wfikkn1	C	T	17: 26,096,765 (GRCm39)	A520T	probably benign	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,274,350 (GRCm39)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,321,042 (GRCm39)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,367,262 (GRCm39)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,256,384 (GRCm39)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,220,900 (GRCm39)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,234,170 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,234,302 (GRCm39)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,274,512 (GRCm39)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,320,500 (GRCm39)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,269,787 (GRCm39)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,281,784 (GRCm39)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,256,414 (GRCm39)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,281,694 (GRCm39)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,311,418 (GRCm39)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,292,660 (GRCm39)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,368,494 (GRCm39)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,274,396 (GRCm39)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,323,146 (GRCm39)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,326,603 (GRCm39)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,245,569 (GRCm39)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,292,572 (GRCm39)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,317,886 (GRCm39)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,275,618 (GRCm39)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,274,027 (GRCm39)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,274,028 (GRCm39)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,300,745 (GRCm39)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,281,726 (GRCm39)	nonsense	probably null
coach	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
Committee	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
Dravrah	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
Harvard	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
horrified	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
lawyer	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
magistrate	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
Maratimus	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
National	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
satirical	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
silky	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
stiggs	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,303,431 (GRCm39)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,358,847 (GRCm39)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,331,096 (GRCm39)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,321,030 (GRCm39)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,349,422 (GRCm39)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,267,771 (GRCm39)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,326,560 (GRCm39)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,286,876 (GRCm39)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,344,468 (GRCm39)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,344,529 (GRCm39)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,332,032 (GRCm39)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,307,222 (GRCm39)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,286,893 (GRCm39)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,307,598 (GRCm39)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,320,991 (GRCm39)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,329,165 (GRCm39)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,351,385 (GRCm39)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,299,428 (GRCm39)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,233,687 (GRCm39)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,344,450 (GRCm39)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,239,278 (GRCm39)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,299,493 (GRCm39)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,323,251 (GRCm39)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,307,100 (GRCm39)	nonsense	probably null
R1952:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R1953:Nbeal1	UTSW	1	60,273,999 (GRCm39)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,245,503 (GRCm39)	missense	probably benign	0.00
R2044:Nbeal1	UTSW	1	60,358,846 (GRCm39)	missense	probably damaging	1.00
R2050:Nbeal1	UTSW	1	60,332,123 (GRCm39)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,350,216 (GRCm39)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,309,515 (GRCm39)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,344,430 (GRCm39)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,321,054 (GRCm39)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,323,165 (GRCm39)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,370,037 (GRCm39)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,276,257 (GRCm39)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,290,511 (GRCm39)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,290,529 (GRCm39)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,317,939 (GRCm39)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,290,572 (GRCm39)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,234,182 (GRCm39)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,233,758 (GRCm39)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,370,107 (GRCm39)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,329,105 (GRCm39)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,306,933 (GRCm39)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,267,890 (GRCm39)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,368,549 (GRCm39)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,274,722 (GRCm39)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,261,352 (GRCm39)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,290,501 (GRCm39)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,292,534 (GRCm39)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,332,062 (GRCm39)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,277,813 (GRCm39)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,276,338 (GRCm39)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,309,487 (GRCm39)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,274,718 (GRCm39)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,367,369 (GRCm39)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,350,158 (GRCm39)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,316,353 (GRCm39)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,276,311 (GRCm39)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,281,761 (GRCm39)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,331,006 (GRCm39)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,311,380 (GRCm39)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,267,950 (GRCm39)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,307,051 (GRCm39)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,287,554 (GRCm39)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,287,564 (GRCm39)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,220,715 (GRCm39)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,261,422 (GRCm39)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,290,466 (GRCm39)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,296,643 (GRCm39)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,261,287 (GRCm39)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,335,083 (GRCm39)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,287,524 (GRCm39)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,277,878 (GRCm39)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,292,633 (GRCm39)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,370,101 (GRCm39)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,320,469 (GRCm39)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,300,745 (GRCm39)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,350,106 (GRCm39)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,299,793 (GRCm39)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,276,317 (GRCm39)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,240,110 (GRCm39)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,349,383 (GRCm39)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,256,355 (GRCm39)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,283,969 (GRCm39)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,233,756 (GRCm39)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,274,626 (GRCm39)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,316,386 (GRCm39)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,283,983 (GRCm39)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,296,609 (GRCm39)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,358,500 (GRCm39)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,331,048 (GRCm39)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,299,591 (GRCm39)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,331,029 (GRCm39)	missense	probably damaging	0.99
R8022:Nbeal1	UTSW	1	60,299,431 (GRCm39)	nonsense	probably null
R8053:Nbeal1	UTSW	1	60,318,954 (GRCm39)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,239,292 (GRCm39)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,276,310 (GRCm39)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,292,640 (GRCm39)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,316,336 (GRCm39)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,274,721 (GRCm39)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,274,316 (GRCm39)	missense	probably benign	0.38
R8753:Nbeal1	UTSW	1	60,307,542 (GRCm39)	missense	probably damaging	1.00
R8769:Nbeal1	UTSW	1	60,274,370 (GRCm39)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,300,743 (GRCm39)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,299,459 (GRCm39)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,329,118 (GRCm39)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,317,885 (GRCm39)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,286,904 (GRCm39)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,331,047 (GRCm39)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,320,425 (GRCm39)	missense	probably damaging	1.00
R9205:Nbeal1	UTSW	1	60,317,839 (GRCm39)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,307,548 (GRCm39)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,297,818 (GRCm39)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,349,424 (GRCm39)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,290,287 (GRCm39)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,274,509 (GRCm39)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,368,544 (GRCm39)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,350,247 (GRCm39)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,299,741 (GRCm39)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,316,391 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GGACTCAAAGGGAAAGTTACGCTTATGT -3'
(R):5'- TGTGGGAACGAAGGCACACAC -3'

Sequencing Primer
(F):5'- GTAAGCTGATTAATGAAGCATGTCTT -3'
(R):5'- gttttcctgtctccattttcatttc -3'

Posted On

2014-03-28