Mutagenetix > Incidental Mutation

Incidental Mutation 'R1468:Usp34'

164690

Institutional Source

Beutler Lab

Gene Symbol

Usp34

Ensembl Gene

ENSMUSG00000056342

Gene Name

ubiquitin specific peptidase 34

Synonyms

Murr2, A530081C03Rik

MMRRC Submission

039521-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.803) question?

Stock #

R1468 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

23256895-23440560 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 23391171 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 2263 (E2263G)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000130131] [ENSMUST00000180046]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000130131
AA Change: E485G

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000115168
Gene: ENSMUSG00000056342
AA Change: E485G

Domain	Start	End	E-Value	Type
low complexity region	33	45	N/A	INTRINSIC
Pfam:UCH	171	514	1.1e-48	PFAM
Pfam:UCH_1	172	470	1.6e-25	PFAM
low complexity region	763	785	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000137823
AA Change: E2263G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000120747
Gene: ENSMUSG00000056342
AA Change: E2263G

Domain	Start	End	E-Value	Type
low complexity region	489	500	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	591	610	N/A	INTRINSIC
coiled coil region	626	671	N/A	INTRINSIC
low complexity region	827	842	N/A	INTRINSIC
low complexity region	1207	1218	N/A	INTRINSIC
low complexity region	1399	1410	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1751	1764	N/A	INTRINSIC
low complexity region	1812	1824	N/A	INTRINSIC
Pfam:UCH	1950	2293	7.6e-44	PFAM
Pfam:UCH_1	1951	2249	3.6e-22	PFAM
low complexity region	2542	2564	N/A	INTRINSIC
low complexity region	2672	2679	N/A	INTRINSIC
Blast:Drf_GBD	2943	3116	3e-53	BLAST
low complexity region	3344	3357	N/A	INTRINSIC
coiled coil region	3371	3393	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000180046
AA Change: E2244G

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000137430
Gene: ENSMUSG00000056342
AA Change: E2244G

Domain	Start	End	E-Value	Type
low complexity region	469	480	N/A	INTRINSIC
low complexity region	510	524	N/A	INTRINSIC
low complexity region	571	590	N/A	INTRINSIC
coiled coil region	607	652	N/A	INTRINSIC
low complexity region	807	822	N/A	INTRINSIC
low complexity region	1187	1198	N/A	INTRINSIC
low complexity region	1379	1390	N/A	INTRINSIC
low complexity region	1498	1512	N/A	INTRINSIC
low complexity region	1731	1744	N/A	INTRINSIC
low complexity region	1792	1804	N/A	INTRINSIC
Pfam:UCH	1930	2273	2.3e-44	PFAM
Pfam:UCH_1	1931	2229	1.1e-22	PFAM
low complexity region	2522	2544	N/A	INTRINSIC
low complexity region	2652	2659	N/A	INTRINSIC
Blast:Drf_GBD	2923	3096	2e-53	BLAST
low complexity region	3324	3337	N/A	INTRINSIC
coiled coil region	3352	3374	N/A	INTRINSIC

Meta Mutation Damage Score

0.6430

Coding Region Coverage

1x: 99.7%
3x: 98.4%
10x: 90.8%
20x: 69.0%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 99 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2900092C05Rik	T	G	7: 12,246,507 (GRCm39)	M1R	probably null	Het
5031439G07Rik	G	T	15: 84,837,345 (GRCm39)	P280T	probably damaging	Het
Abca2	C	T	2: 25,331,308 (GRCm39)	S1267L	probably damaging	Het
Acsl3	A	T	1: 78,684,126 (GRCm39)	R719S	probably benign	Het
Adam1a	A	T	5: 121,657,839 (GRCm39)		probably null	Het
Aldh6a1	T	C	12: 84,488,544 (GRCm39)	E89G	possibly damaging	Het
Ankrd36	A	G	11: 5,525,752 (GRCm39)	Y238C	probably damaging	Het
Ankrd65	G	A	4: 155,877,362 (GRCm39)	R291Q	probably benign	Het
Ano2	C	T	6: 125,773,227 (GRCm39)	R287W	probably damaging	Het
Ap1ar	A	G	3: 127,606,215 (GRCm39)	I125T	probably benign	Het
Arid1b	A	G	17: 5,293,197 (GRCm39)	D705G	probably damaging	Het
Asb18	T	A	1: 89,924,005 (GRCm39)	N86I	probably damaging	Het
Bicral	A	T	17: 47,135,519 (GRCm39)	S564T	probably benign	Het
Bpifa6	A	G	2: 153,831,192 (GRCm39)	M253V	probably benign	Het
Braf	T	C	6: 39,642,017 (GRCm39)	D194G	probably damaging	Het
Brinp3	C	A	1: 146,777,700 (GRCm39)	P716T	probably benign	Het
C7	T	A	15: 5,041,631 (GRCm39)	Y425F	probably damaging	Het
Ccdc102a	T	C	8: 95,632,714 (GRCm39)	K421R	probably benign	Het
Cep89	G	A	7: 35,120,388 (GRCm39)		probably null	Het
Chgb	A	T	2: 132,634,720 (GRCm39)	M221L	probably benign	Het
Chst14	A	G	2: 118,758,145 (GRCm39)	Y313C	probably damaging	Het
Ciita	G	A	16: 10,331,152 (GRCm39)		probably null	Het
Clec12b	A	T	6: 129,357,603 (GRCm39)	I85N	probably damaging	Het
Clec2e	G	T	6: 129,070,459 (GRCm39)	Y187*	probably null	Het
Crbn	T	C	6: 106,767,804 (GRCm39)	K229E	probably benign	Het
Ctdspl2	A	T	2: 121,811,762 (GRCm39)	Q201L	probably benign	Het
Cyp2c55	T	A	19: 38,999,525 (GRCm39)	V77E	probably damaging	Het
Cyp2c69	A	C	19: 39,837,839 (GRCm39)	D414E	probably damaging	Het
Dlg1	A	G	16: 31,661,640 (GRCm39)		probably null	Het
Dnah5	C	A	15: 28,230,609 (GRCm39)	S169*	probably null	Het
Dock4	C	A	12: 40,805,809 (GRCm39)	T927K	probably benign	Het
Esrp2	T	G	8: 106,860,453 (GRCm39)	D259A	probably damaging	Het
Fam169a	A	G	13: 97,255,038 (GRCm39)	K418R	probably benign	Het
Fancm	A	T	12: 65,146,067 (GRCm39)	I597F	probably damaging	Het
Fat1	G	A	8: 45,463,582 (GRCm39)	V1375M	probably damaging	Het
Fbxw10	A	T	11: 62,753,464 (GRCm39)	D486V	probably damaging	Het
Fermt1	C	T	2: 132,766,942 (GRCm39)	E342K	probably benign	Het
Foxp1	T	A	6: 98,955,181 (GRCm39)	H195L	possibly damaging	Het
Gfra1	T	A	19: 58,440,407 (GRCm39)	I138L	probably benign	Het
Gm12185	T	C	11: 48,806,501 (GRCm39)	D230G	possibly damaging	Het
Gpd2	A	C	2: 57,245,786 (GRCm39)	T439P	probably damaging	Het
Gpm6a	A	T	8: 55,490,385 (GRCm39)	K20N	probably damaging	Het
Hc	A	T	2: 34,873,819 (GRCm39)	Y158*	probably null	Het
Hectd4	A	T	5: 121,487,235 (GRCm39)	D3410V	possibly damaging	Het
Il17b	G	A	18: 61,823,483 (GRCm39)		probably null	Het
Irx4	G	T	13: 73,413,695 (GRCm39)	R55L	possibly damaging	Het
Lama3	T	C	18: 12,574,164 (GRCm39)	V582A	probably benign	Het
Ldhd	G	T	8: 112,353,925 (GRCm39)	A425E	possibly damaging	Het
Lrp1b	C	T	2: 40,817,841 (GRCm39)		probably null	Het
Lrp5	T	C	19: 3,670,191 (GRCm39)	T638A	possibly damaging	Het
Lrrk1	A	C	7: 65,909,722 (GRCm39)	F1996C	probably damaging	Het
Ly6h	G	A	15: 75,437,986 (GRCm39)	S21L	probably benign	Het
Mctp1	T	C	13: 76,973,392 (GRCm39)	V431A	probably benign	Het
Metap2	C	T	10: 93,707,345 (GRCm39)		probably null	Het
Mfsd2b	T	A	12: 4,920,536 (GRCm39)	K94*	probably null	Het
Micall2	A	G	5: 139,705,097 (GRCm39)	L79P	probably damaging	Het
Mucl2	T	C	15: 103,927,673 (GRCm39)	T95A	possibly damaging	Het
Myo15a	A	T	11: 60,396,832 (GRCm39)	T2634S	probably damaging	Het
Myo5b	G	T	18: 74,873,574 (GRCm39)	V1467L	probably damaging	Het
Nfic	G	T	10: 81,256,414 (GRCm39)	D105E	probably damaging	Het
Nrdc	T	A	4: 108,873,865 (GRCm39)	F227Y	probably benign	Het
Nrp2	A	T	1: 62,777,458 (GRCm39)	I88F	probably damaging	Het
Nup160	A	T	2: 90,530,887 (GRCm39)	H515L	probably benign	Het
Nup205	G	A	6: 35,202,917 (GRCm39)		probably null	Het
Oas1g	G	A	5: 121,020,069 (GRCm39)	T179I	probably benign	Het
Ogfr	A	T	2: 180,236,543 (GRCm39)	E376V	probably damaging	Het
Or2l13	T	G	16: 19,306,378 (GRCm39)	S263R	probably benign	Het
Or4a69	A	T	2: 89,312,855 (GRCm39)	V208D	possibly damaging	Het
Or4c107	T	G	2: 88,789,387 (GRCm39)	Y192*	probably null	Het
Or52d1	G	T	7: 103,755,896 (GRCm39)	V137F	possibly damaging	Het
Or5p6	C	T	7: 107,631,595 (GRCm39)		probably null	Het
Pard3b	T	C	1: 62,384,188 (GRCm39)	V851A	probably benign	Het
Pcdhb16	A	T	18: 37,611,142 (GRCm39)	Y34F	probably damaging	Het
Pikfyve	T	C	1: 65,290,825 (GRCm39)	Y1215H	probably damaging	Het
Pkhd1	A	T	1: 20,593,565 (GRCm39)	V1516E	probably damaging	Het
Ptprg	A	T	14: 12,190,767 (GRCm38)	I818F	probably benign	Het
Ralgapb	A	G	2: 158,304,173 (GRCm39)	E644G	possibly damaging	Het
Rbm45	A	G	2: 76,202,459 (GRCm39)	I127M	probably damaging	Het
Rtp2	T	C	16: 23,746,220 (GRCm39)	Y157C	probably damaging	Het
Sf3b3	A	T	8: 111,564,006 (GRCm39)	Y329N	probably damaging	Het
Sfxn1	A	G	13: 54,239,646 (GRCm39)		probably null	Het
Shkbp1	A	T	7: 27,044,751 (GRCm39)	C447S	probably damaging	Het
Sipa1l3	A	G	7: 29,021,685 (GRCm39)	S689P	possibly damaging	Het
Slc7a8	A	G	14: 54,970,656 (GRCm39)	S332P	probably damaging	Het
Slit1	C	A	19: 41,596,823 (GRCm39)	C1092F	probably damaging	Het
Stard9	A	G	2: 120,533,678 (GRCm39)	I619V	possibly damaging	Het
Sycp3	T	C	10: 88,305,454 (GRCm39)	V185A	possibly damaging	Het
Taar9	A	T	10: 23,985,382 (GRCm39)	N17K	possibly damaging	Het
Tbkbp1	T	C	11: 97,039,814 (GRCm39)	E102G	probably damaging	Het
Tex44	A	G	1: 86,354,834 (GRCm39)	N248D	probably benign	Het
Tmem63b	C	G	17: 45,989,904 (GRCm39)	R88P	possibly damaging	Het
Tnpo1	C	T	13: 98,986,665 (GRCm39)	V781I	probably benign	Het
Tonsl	C	T	15: 76,520,761 (GRCm39)		probably null	Het
Ttc6	A	G	12: 57,721,463 (GRCm39)	K984R	possibly damaging	Het
Usp8	A	G	2: 126,596,847 (GRCm39)	K875E	probably damaging	Het
Vmn1r223	A	G	13: 23,434,038 (GRCm39)	I211V	possibly damaging	Het
Vmn2r81	G	A	10: 79,129,496 (GRCm39)	V796I	probably damaging	Het
Wdr90	A	T	17: 26,073,027 (GRCm39)	V856D	probably damaging	Het
Wnk2	T	A	13: 49,235,571 (GRCm39)	T615S	probably damaging	Het

Other mutations in Usp34

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00092:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL00477:Usp34	APN	11	23,418,879 (GRCm39)	missense	probably damaging	0.99
IGL01307:Usp34	APN	11	23,367,676 (GRCm39)	missense	probably damaging	0.99
IGL01313:Usp34	APN	11	23,423,206 (GRCm39)	missense	probably damaging	1.00
IGL01794:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01826:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01827:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01830:Usp34	APN	11	23,386,020 (GRCm39)	missense	probably damaging	0.98
IGL01867:Usp34	APN	11	23,334,411 (GRCm39)	missense	possibly damaging	0.77
IGL01939:Usp34	APN	11	23,295,141 (GRCm39)	splice site	probably benign
IGL01977:Usp34	APN	11	23,402,661 (GRCm39)	missense	probably damaging	1.00
IGL01985:Usp34	APN	11	23,402,565 (GRCm39)	missense	probably damaging	1.00
IGL02011:Usp34	APN	11	23,421,554 (GRCm39)	missense	probably damaging	0.99
IGL02302:Usp34	APN	11	23,417,243 (GRCm39)	missense	possibly damaging	0.91
IGL02423:Usp34	APN	11	23,304,900 (GRCm39)	missense	probably benign	0.11
IGL02491:Usp34	APN	11	23,382,630 (GRCm39)	missense	probably damaging	0.98
IGL02532:Usp34	APN	11	23,320,291 (GRCm39)	missense	probably damaging	0.99
IGL02561:Usp34	APN	11	23,301,652 (GRCm39)	missense	probably benign	0.09
IGL02706:Usp34	APN	11	23,338,659 (GRCm39)	splice site	probably benign
IGL02891:Usp34	APN	11	23,437,166 (GRCm39)	missense	probably benign	0.09
IGL03079:Usp34	APN	11	23,382,247 (GRCm39)	missense	possibly damaging	0.48
IGL03089:Usp34	APN	11	23,396,958 (GRCm39)	missense	possibly damaging	0.84
IGL03175:Usp34	APN	11	23,438,686 (GRCm39)	missense	probably benign
IGL03256:Usp34	APN	11	23,370,090 (GRCm39)	nonsense	probably null
IGL03280:Usp34	APN	11	23,304,897 (GRCm39)	missense	probably damaging	1.00
IGL03289:Usp34	APN	11	23,343,818 (GRCm39)	missense	possibly damaging	0.94
IGL03408:Usp34	APN	11	23,396,957 (GRCm39)	missense	possibly damaging	0.92
Chub	UTSW	11	23,414,686 (GRCm39)	missense	probably damaging	0.99
Cicione	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R5571_Usp34_680	UTSW	11	23,407,975 (GRCm39)	missense	probably damaging	0.99
R5713_Usp34_003	UTSW	11	23,293,515 (GRCm39)	missense	possibly damaging	0.94
Roebuck	UTSW	11	23,436,810 (GRCm39)	splice site	probably benign
stoat	UTSW	11	23,437,203 (GRCm39)	missense
tunnelvision	UTSW	11	23,396,968 (GRCm39)	missense
I2288:Usp34	UTSW	11	23,382,473 (GRCm39)	splice site	probably benign
R0047:Usp34	UTSW	11	23,414,403 (GRCm39)	missense	probably benign	0.34
R0047:Usp34	UTSW	11	23,414,403 (GRCm39)	missense	probably benign	0.34
R0099:Usp34	UTSW	11	23,313,111 (GRCm39)	missense	probably damaging	1.00
R0240:Usp34	UTSW	11	23,383,206 (GRCm39)	missense	probably damaging	0.99
R0240:Usp34	UTSW	11	23,383,206 (GRCm39)	missense	probably damaging	0.99
R0403:Usp34	UTSW	11	23,283,838 (GRCm39)	missense	possibly damaging	0.82
R0432:Usp34	UTSW	11	23,351,505 (GRCm39)	missense	probably damaging	0.99
R0446:Usp34	UTSW	11	23,417,207 (GRCm39)	missense	probably damaging	0.97
R0455:Usp34	UTSW	11	23,396,741 (GRCm39)	splice site	probably benign
R0470:Usp34	UTSW	11	23,386,001 (GRCm39)	missense	possibly damaging	0.94
R0472:Usp34	UTSW	11	23,334,509 (GRCm39)	splice site	probably benign
R0512:Usp34	UTSW	11	23,401,997 (GRCm39)	missense	probably benign	0.04
R0557:Usp34	UTSW	11	23,353,848 (GRCm39)	missense	probably damaging	0.98
R0562:Usp34	UTSW	11	23,382,406 (GRCm39)	splice site	probably benign
R0656:Usp34	UTSW	11	23,422,967 (GRCm39)	missense	probably damaging	0.99
R0693:Usp34	UTSW	11	23,402,637 (GRCm39)	missense	probably damaging	0.97
R0739:Usp34	UTSW	11	23,417,243 (GRCm39)	missense	possibly damaging	0.91
R1061:Usp34	UTSW	11	23,334,420 (GRCm39)	missense	possibly damaging	0.51
R1078:Usp34	UTSW	11	23,383,175 (GRCm39)	splice site	probably benign
R1223:Usp34	UTSW	11	23,396,464 (GRCm39)	splice site	probably null
R1295:Usp34	UTSW	11	23,334,477 (GRCm39)	missense	probably damaging	1.00
R1430:Usp34	UTSW	11	23,409,151 (GRCm39)	missense	probably damaging	0.97
R1445:Usp34	UTSW	11	23,301,629 (GRCm39)	missense	probably damaging	0.99
R1468:Usp34	UTSW	11	23,391,171 (GRCm39)	missense	probably damaging	1.00
R1471:Usp34	UTSW	11	23,438,862 (GRCm39)	missense	probably benign	0.20
R1475:Usp34	UTSW	11	23,423,253 (GRCm39)	missense	probably damaging	0.99
R1628:Usp34	UTSW	11	23,438,725 (GRCm39)	missense	probably damaging	1.00
R1631:Usp34	UTSW	11	23,410,651 (GRCm39)	missense	probably damaging	0.99
R1655:Usp34	UTSW	11	23,325,051 (GRCm39)	missense	probably benign	0.05
R1741:Usp34	UTSW	11	23,314,103 (GRCm39)	missense	probably benign	0.00
R1854:Usp34	UTSW	11	23,376,153 (GRCm39)	missense	probably benign	0.24
R1867:Usp34	UTSW	11	23,311,593 (GRCm39)	missense	possibly damaging	0.82
R1869:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1870:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1871:Usp34	UTSW	11	23,314,479 (GRCm39)	missense	probably benign	0.37
R1967:Usp34	UTSW	11	23,314,503 (GRCm39)	missense	probably benign	0.01
R2051:Usp34	UTSW	11	23,414,468 (GRCm39)	missense	probably damaging	0.97
R2132:Usp34	UTSW	11	23,414,556 (GRCm39)	missense	possibly damaging	0.95
R2156:Usp34	UTSW	11	23,332,602 (GRCm39)	missense	probably damaging	0.98
R2205:Usp34	UTSW	11	23,335,147 (GRCm39)	missense	probably damaging	0.97
R2342:Usp34	UTSW	11	23,353,599 (GRCm39)	missense	possibly damaging	0.46
R3431:Usp34	UTSW	11	23,320,466 (GRCm39)	missense	possibly damaging	0.95
R3812:Usp34	UTSW	11	23,414,517 (GRCm39)	missense	possibly damaging	0.94
R3872:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3873:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3874:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3875:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R3925:Usp34	UTSW	11	23,293,640 (GRCm39)	missense	probably benign	0.28
R3972:Usp34	UTSW	11	23,407,803 (GRCm39)	missense	probably damaging	1.00
R4018:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R4042:Usp34	UTSW	11	23,439,033 (GRCm39)	missense	possibly damaging	0.85
R4155:Usp34	UTSW	11	23,367,676 (GRCm39)	missense	probably damaging	0.99
R4197:Usp34	UTSW	11	23,394,189 (GRCm39)	missense	probably damaging	0.98
R4352:Usp34	UTSW	11	23,270,727 (GRCm39)	missense	possibly damaging	0.73
R4379:Usp34	UTSW	11	23,334,499 (GRCm39)	missense	possibly damaging	0.52
R4444:Usp34	UTSW	11	23,385,998 (GRCm39)	missense	probably damaging	0.98
R4475:Usp34	UTSW	11	23,407,975 (GRCm39)	missense	possibly damaging	0.95
R4501:Usp34	UTSW	11	23,351,529 (GRCm39)	missense	probably damaging	1.00
R4527:Usp34	UTSW	11	23,371,257 (GRCm39)	missense	possibly damaging	0.57
R4603:Usp34	UTSW	11	23,414,633 (GRCm39)	missense	probably damaging	0.97
R4612:Usp34	UTSW	11	23,382,268 (GRCm39)	missense	probably damaging	0.99
R4673:Usp34	UTSW	11	23,314,480 (GRCm39)	small deletion	probably benign
R4707:Usp34	UTSW	11	23,437,215 (GRCm39)	missense	probably damaging	1.00
R4736:Usp34	UTSW	11	23,343,749 (GRCm39)	splice site	probably null
R4867:Usp34	UTSW	11	23,401,999 (GRCm39)	missense	probably benign	0.28
R4879:Usp34	UTSW	11	23,323,410 (GRCm39)	missense	possibly damaging	0.94
R4977:Usp34	UTSW	11	23,438,982 (GRCm39)	missense	probably damaging	1.00
R5004:Usp34	UTSW	11	23,414,586 (GRCm39)	missense	probably damaging	1.00
R5057:Usp34	UTSW	11	23,408,086 (GRCm39)	intron	probably benign
R5068:Usp34	UTSW	11	23,410,665 (GRCm39)	missense	possibly damaging	0.94
R5304:Usp34	UTSW	11	23,293,616 (GRCm39)	missense	probably damaging	1.00
R5320:Usp34	UTSW	11	23,283,739 (GRCm39)	missense	probably benign
R5327:Usp34	UTSW	11	23,418,846 (GRCm39)	missense	probably damaging	1.00
R5328:Usp34	UTSW	11	23,438,659 (GRCm39)	missense	probably benign	0.04
R5328:Usp34	UTSW	11	23,414,616 (GRCm39)	missense	probably benign	0.01
R5390:Usp34	UTSW	11	23,394,202 (GRCm39)	critical splice donor site	probably null
R5434:Usp34	UTSW	11	23,362,271 (GRCm39)	missense	probably damaging	0.99
R5523:Usp34	UTSW	11	23,299,198 (GRCm39)	missense	probably benign	0.39
R5567:Usp34	UTSW	11	23,438,336 (GRCm39)	missense	probably damaging	0.97
R5571:Usp34	UTSW	11	23,407,975 (GRCm39)	missense	probably damaging	0.99
R5645:Usp34	UTSW	11	23,325,024 (GRCm39)	missense	possibly damaging	0.86
R5713:Usp34	UTSW	11	23,293,515 (GRCm39)	missense	possibly damaging	0.94
R5719:Usp34	UTSW	11	23,304,846 (GRCm39)	missense	probably benign	0.00
R5813:Usp34	UTSW	11	23,371,340 (GRCm39)	missense	probably benign	0.38
R5921:Usp34	UTSW	11	23,414,686 (GRCm39)	missense	probably damaging	0.99
R5928:Usp34	UTSW	11	23,386,040 (GRCm39)	missense	probably damaging	0.98
R5944:Usp34	UTSW	11	23,313,089 (GRCm39)	missense	probably damaging	1.00
R6198:Usp34	UTSW	11	23,434,127 (GRCm39)	missense	probably damaging	1.00
R6229:Usp34	UTSW	11	23,396,778 (GRCm39)	missense	probably damaging	0.99
R6306:Usp34	UTSW	11	23,362,260 (GRCm39)	missense	possibly damaging	0.94
R6320:Usp34	UTSW	11	23,402,520 (GRCm39)	missense	probably damaging	0.98
R6341:Usp34	UTSW	11	23,331,353 (GRCm39)	missense	probably damaging	0.97
R6374:Usp34	UTSW	11	23,388,914 (GRCm39)	missense	probably damaging	1.00
R6398:Usp34	UTSW	11	23,438,666 (GRCm39)	missense	probably benign
R6438:Usp34	UTSW	11	23,314,266 (GRCm39)	missense	probably benign	0.02
R6668:Usp34	UTSW	11	23,410,659 (GRCm39)	missense	probably damaging	0.97
R6700:Usp34	UTSW	11	23,389,011 (GRCm39)	missense	probably damaging	1.00
R6783:Usp34	UTSW	11	23,362,318 (GRCm39)	missense	probably damaging	1.00
R6821:Usp34	UTSW	11	23,317,491 (GRCm39)	missense	possibly damaging	0.79
R6855:Usp34	UTSW	11	23,402,569 (GRCm39)	missense	possibly damaging	0.94
R6916:Usp34	UTSW	11	23,408,023 (GRCm39)	missense	probably damaging	0.98
R7020:Usp34	UTSW	11	23,343,954 (GRCm39)	missense	probably benign	0.05
R7026:Usp34	UTSW	11	23,311,622 (GRCm39)	missense	probably damaging	1.00
R7085:Usp34	UTSW	11	23,313,097 (GRCm39)	missense
R7101:Usp34	UTSW	11	23,376,183 (GRCm39)	missense
R7168:Usp34	UTSW	11	23,414,585 (GRCm39)	missense
R7192:Usp34	UTSW	11	23,410,571 (GRCm39)	missense
R7264:Usp34	UTSW	11	23,283,566 (GRCm39)	missense	probably benign	0.00
R7325:Usp34	UTSW	11	23,369,052 (GRCm39)	missense
R7343:Usp34	UTSW	11	23,438,868 (GRCm39)	missense
R7358:Usp34	UTSW	11	23,311,683 (GRCm39)	missense	probably damaging	0.99
R7369:Usp34	UTSW	11	23,382,361 (GRCm39)	missense
R7389:Usp34	UTSW	11	23,295,200 (GRCm39)	missense
R7459:Usp34	UTSW	11	23,314,458 (GRCm39)	missense	possibly damaging	0.53
R7517:Usp34	UTSW	11	23,396,968 (GRCm39)	missense
R7729:Usp34	UTSW	11	23,399,268 (GRCm39)	missense
R7777:Usp34	UTSW	11	23,332,638 (GRCm39)	missense
R7810:Usp34	UTSW	11	23,362,314 (GRCm39)	missense
R7836:Usp34	UTSW	11	23,396,614 (GRCm39)	missense
R7862:Usp34	UTSW	11	23,414,718 (GRCm39)	missense
R7993:Usp34	UTSW	11	23,327,622 (GRCm39)	missense
R8050:Usp34	UTSW	11	23,396,787 (GRCm39)	missense
R8054:Usp34	UTSW	11	23,311,295 (GRCm39)	missense
R8239:Usp34	UTSW	11	23,396,750 (GRCm39)	missense
R8266:Usp34	UTSW	11	23,436,810 (GRCm39)	splice site	probably benign
R8347:Usp34	UTSW	11	23,362,345 (GRCm39)	missense
R8409:Usp34	UTSW	11	23,407,811 (GRCm39)	missense
R8692:Usp34	UTSW	11	23,379,325 (GRCm39)	missense
R8694:Usp34	UTSW	11	23,434,161 (GRCm39)	missense
R8734:Usp34	UTSW	11	23,394,184 (GRCm39)	missense
R8806:Usp34	UTSW	11	23,434,143 (GRCm39)	missense
R8914:Usp34	UTSW	11	23,293,604 (GRCm39)	missense
R8987:Usp34	UTSW	11	23,414,267 (GRCm39)	missense
R9013:Usp34	UTSW	11	23,320,302 (GRCm39)	missense
R9108:Usp34	UTSW	11	23,320,528 (GRCm39)	missense
R9264:Usp34	UTSW	11	23,439,064 (GRCm39)	missense
R9301:Usp34	UTSW	11	23,422,951 (GRCm39)	missense
R9375:Usp34	UTSW	11	23,437,203 (GRCm39)	missense
R9385:Usp34	UTSW	11	23,399,223 (GRCm39)	missense
R9500:Usp34	UTSW	11	23,331,337 (GRCm39)	missense	probably damaging	0.99
R9566:Usp34	UTSW	11	23,317,529 (GRCm39)	missense
R9629:Usp34	UTSW	11	23,314,364 (GRCm39)	missense
R9679:Usp34	UTSW	11	23,394,369 (GRCm39)	missense
R9680:Usp34	UTSW	11	23,317,385 (GRCm39)	missense	possibly damaging	0.94
R9686:Usp34	UTSW	11	23,424,351 (GRCm39)	missense
R9752:Usp34	UTSW	11	23,409,182 (GRCm39)	missense	probably benign	0.11
X0023:Usp34	UTSW	11	23,325,028 (GRCm39)	missense	possibly damaging	0.73
X0057:Usp34	UTSW	11	23,407,824 (GRCm39)	missense	possibly damaging	0.86
Z1176:Usp34	UTSW	11	23,423,221 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

Posted On

2014-03-28