Mutagenetix > Incidental Mutation

Incidental Mutation 'R1471:Akap6'

164921

Institutional Source

Beutler Lab

Gene Symbol

Akap6

Ensembl Gene

ENSMUSG00000061603

Gene Name

A kinase (PRKA) anchor protein 6

Synonyms

MMRRC Submission

039524-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.868) question?

Stock #

R1471 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

52699383-53155599 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 53141496 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1898 (T1898A)

Ref Sequence

ENSEMBL: ENSMUSP00000093406 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095737] [ENSMUST00000219786]

AlphaFold

E9Q9K8

Predicted Effect

probably benign
Transcript: ENSMUST00000095737
AA Change: T1898A

PolyPhen 2 Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000093406
Gene: ENSMUSG00000061603
AA Change: T1898A

Domain	Start	End	E-Value	Type
low complexity region	34	51	N/A	INTRINSIC
Blast:SPEC	66	168	2e-50	BLAST
low complexity region	441	455	N/A	INTRINSIC
low complexity region	544	555	N/A	INTRINSIC
low complexity region	569	587	N/A	INTRINSIC
low complexity region	640	651	N/A	INTRINSIC
low complexity region	694	708	N/A	INTRINSIC
SPEC	779	880	1.06e-1	SMART
SPEC	959	1057	1.45e0	SMART
SPEC	1078	1185	2.56e-2	SMART
low complexity region	1316	1332	N/A	INTRINSIC
low complexity region	1555	1568	N/A	INTRINSIC
low complexity region	1610	1622	N/A	INTRINSIC
low complexity region	1683	1698	N/A	INTRINSIC
low complexity region	1737	1781	N/A	INTRINSIC
low complexity region	1899	1910	N/A	INTRINSIC
low complexity region	2019	2031	N/A	INTRINSIC
low complexity region	2104	2115	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000219786

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 96.8%
20x: 94.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
PHENOTYPE: Targeted disruption of this gene results in partial embryonic lethality; surviving homozygotes display a decreased body weight, craniofacial defects and reduced viability. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 96 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610010F05Rik	A	T	11: 23,615,222 (GRCm38)	M255K	probably damaging	Het
4930486L24Rik	C	A	13: 60,853,522 (GRCm38)	K130N	probably damaging	Het
Adam6a	T	A	12: 113,544,393 (GRCm38)	S129T	probably damaging	Het
Adamts10	T	A	17: 33,553,138 (GRCm38)	F1087I	probably damaging	Het
Afp	T	A	5: 90,503,682 (GRCm38)	N385K	possibly damaging	Het
Ahnak	T	G	19: 9,012,932 (GRCm38)		probably benign	Het
Antxr2	C	A	5: 97,975,340 (GRCm38)	V283F	possibly damaging	Het
Asgr1	T	C	11: 70,056,093 (GRCm38)	V55A	possibly damaging	Het
Asxl3	A	G	18: 22,516,354 (GRCm38)	K467E	probably damaging	Het
Atp5a1	C	A	18: 77,781,269 (GRCm38)	Q398K	probably damaging	Het
Atxn2	T	A	5: 121,786,374 (GRCm38)	D455E	probably damaging	Het
B4galt6	C	T	18: 20,745,353 (GRCm38)	A39T	possibly damaging	Het
C130073F10Rik	C	T	4: 101,890,338 (GRCm38)	E165K	probably benign	Het
Cabin1	A	G	10: 75,694,792 (GRCm38)	C1519R	probably damaging	Het
Casp8ap2	C	T	4: 32,639,386 (GRCm38)	R147*	probably null	Het
Ccdc88b	A	G	19: 6,854,023 (GRCm38)	L517P	probably benign	Het
Cd109	G	A	9: 78,654,587 (GRCm38)	V220I	probably damaging	Het
Cd2ap	T	C	17: 42,820,597 (GRCm38)	K369R	probably benign	Het
Cd300c	A	G	11: 114,959,788 (GRCm38)	V63A	probably benign	Het
Cnot10	A	G	9: 114,591,551 (GRCm38)	V741A	probably benign	Het
Col18a1	G	T	10: 77,096,206 (GRCm38)	Q350K	unknown	Het
Crnkl1	T	C	2: 145,932,316 (GRCm38)	K76E	possibly damaging	Het
Cryzl2	A	G	1: 157,470,721 (GRCm38)	K227E	probably benign	Het
Cts6	G	A	13: 61,196,380 (GRCm38)	T286I	probably benign	Het
Cul1	T	C	6: 47,514,886 (GRCm38)	V392A	probably damaging	Het
Dcaf7	T	A	11: 106,046,747 (GRCm38)	F65L	probably benign	Het
Dgke	A	C	11: 89,055,494 (GRCm38)	V160G	possibly damaging	Het
Dock8	C	A	19: 25,201,036 (GRCm38)	Q2098K	possibly damaging	Het
Efhb	T	A	17: 53,399,112 (GRCm38)	D799V	possibly damaging	Het
Ephb2	T	C	4: 136,658,951 (GRCm38)	D829G	probably benign	Het
Exosc1	A	T	19: 41,924,718 (GRCm38)	S117R	probably damaging	Het
Fga	T	C	3: 83,028,618 (GRCm38)	S51P	probably benign	Het
Fmn1	T	C	2: 113,693,094 (GRCm38)	F1141L	possibly damaging	Het
Foxm1	C	T	6: 128,373,874 (GRCm38)	L713F	probably damaging	Het
Galnt4	A	G	10: 99,108,674 (GRCm38)	E87G	probably benign	Het
Gamt	T	C	10: 80,260,858 (GRCm38)	D15G	probably benign	Het
Gm13101	T	C	4: 143,964,953 (GRCm38)	N400S	probably benign	Het
Gm15557	C	A	2: 155,942,254 (GRCm38)	D154E	possibly damaging	Het
Gnptab	A	G	10: 88,445,763 (GRCm38)	I1211V	probably benign	Het
Greb1	A	T	12: 16,711,774 (GRCm38)	M535K	probably damaging	Het
Grm8	C	A	6: 27,363,309 (GRCm38)	A736S	possibly damaging	Het
Hspa14	T	C	2: 3,491,608 (GRCm38)	I373M	probably benign	Het
Ifi207	T	A	1: 173,730,063 (GRCm38)	T370S	unknown	Het
Igf1r	A	G	7: 68,003,837 (GRCm38)	N41S	probably damaging	Het
Ikzf5	A	T	7: 131,391,767 (GRCm38)	V224D	probably damaging	Het
Il10	C	A	1: 131,021,373 (GRCm38)	Y90*	probably null	Het
Itga4	A	G	2: 79,287,032 (GRCm38)	D394G	probably benign	Het
Kif21a	A	T	15: 90,956,419 (GRCm38)	S1165T	probably benign	Het
Krtap14	A	G	16: 88,825,627 (GRCm38)	S155P	probably damaging	Het
Loxl2	A	G	14: 69,693,097 (GRCm38)	N770S	probably benign	Het
Man2b1	A	G	8: 85,086,845 (GRCm38)	D222G	probably damaging	Het
Mcub	T	A	3: 129,915,815 (GRCm38)	Y283F	probably damaging	Het
Meis3	T	A	7: 16,177,571 (GRCm38)	Y64*	probably null	Het
Mfsd6	T	A	1: 52,709,557 (GRCm38)	I50F	probably benign	Het
Micu2	T	C	14: 57,945,397 (GRCm38)	T165A	probably damaging	Het
Mtcl1	T	C	17: 66,379,148 (GRCm38)	E921G	probably damaging	Het
Muc5b	A	T	7: 141,843,234 (GRCm38)	N215Y	unknown	Het
Muc6	A	G	7: 141,647,909 (GRCm38)	F772L	possibly damaging	Het
Myt1	A	G	2: 181,797,111 (GRCm38)	D142G	probably benign	Het
Nol6	C	T	4: 41,120,281 (GRCm38)	V479I	probably benign	Het
Nsun7	A	G	5: 66,284,229 (GRCm38)	K414E	probably benign	Het
Nup210l	A	C	3: 90,170,562 (GRCm38)	I914L	probably benign	Het
Obox3	G	A	7: 15,626,950 (GRCm38)	P88L	probably benign	Het
Olfr1098	C	T	2: 86,922,578 (GRCm38)		probably null	Het
Olfr1122	A	G	2: 87,388,518 (GRCm38)	Y271C	probably damaging	Het
Olfr1132	T	C	2: 87,635,670 (GRCm38)	T26A	probably benign	Het
Olfr1289	T	C	2: 111,484,006 (GRCm38)	L192P	probably damaging	Het
Pclo	T	C	5: 14,680,427 (GRCm38)		probably benign	Het
Pcsk5	T	C	19: 17,568,324 (GRCm38)	N745D	probably damaging	Het
Pdzrn3	T	A	6: 101,151,512 (GRCm38)	N731I	possibly damaging	Het
Pkdrej	T	A	15: 85,817,133 (GRCm38)	Q1534L	probably benign	Het
Rell1	T	A	5: 63,936,085 (GRCm38)	D109V	probably damaging	Het
Rplp0	C	T	5: 115,563,344 (GRCm38)	T285I	probably damaging	Het
Sema3g	C	T	14: 31,228,045 (GRCm38)	R728C	probably damaging	Het
Slc15a2	A	G	16: 36,753,791 (GRCm38)	Y536H	probably damaging	Het
Slc26a5	T	A	5: 21,816,964 (GRCm38)	Y488F	probably benign	Het
Slc5a4a	A	T	10: 76,186,528 (GRCm38)	S566C	probably damaging	Het
Spink7	C	T	18: 62,596,204 (GRCm38)	E21K	possibly damaging	Het
Src	C	T	2: 157,457,187 (GRCm38)	Q35*	probably null	Het
Srrm2	T	A	17: 23,820,796 (GRCm38)	V2234E	probably damaging	Het
Stk36	A	T	1: 74,611,155 (GRCm38)	Q282L	probably benign	Het
Tas2r118	T	G	6: 23,969,171 (GRCm38)	E297A	probably damaging	Het
Terf1	A	G	1: 15,842,970 (GRCm38)	Y385C	probably damaging	Het
Tmc3	T	C	7: 83,598,290 (GRCm38)	S198P	probably damaging	Het
Tmprss11b	C	T	5: 86,660,496 (GRCm38)	R407H	possibly damaging	Het
Tspyl4	G	A	10: 34,298,111 (GRCm38)	E200K	probably damaging	Het
Ttc21a	T	C	9: 119,942,641 (GRCm38)	Y169H	probably damaging	Het
Ugt2b36	C	T	5: 87,092,071 (GRCm38)	D152N	probably damaging	Het
Unk	T	C	11: 116,049,409 (GRCm38)	I196T	probably benign	Het
Uroc1	T	G	6: 90,344,171 (GRCm38)	V243G	probably damaging	Het
Usp34	C	A	11: 23,488,862 (GRCm38)	Q3475K	probably benign	Het
Vmn2r117	T	A	17: 23,478,473 (GRCm38)	I82L	probably benign	Het
Vmn2r44	A	T	7: 8,377,883 (GRCm38)	V337E	probably damaging	Het
Zbtb14	C	A	17: 69,388,502 (GRCm38)	F398L	probably damaging	Het
Zfp362	T	C	4: 128,787,200 (GRCm38)	T111A	probably benign	Het
Zfp598	T	C	17: 24,680,072 (GRCm38)	V615A	probably benign	Het

Other mutations in Akap6

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Akap6	APN	12	53,140,980 (GRCm38)	missense	possibly damaging	0.79
IGL00505:Akap6	APN	12	52,887,102 (GRCm38)	missense	possibly damaging	0.92
IGL01134:Akap6	APN	12	52,937,217 (GRCm38)	missense	probably damaging	0.96
IGL01458:Akap6	APN	12	52,886,818 (GRCm38)	nonsense	probably null
IGL01589:Akap6	APN	12	53,139,664 (GRCm38)	missense	probably damaging	1.00
IGL01592:Akap6	APN	12	53,142,142 (GRCm38)	missense	probably damaging	1.00
IGL01738:Akap6	APN	12	52,886,817 (GRCm38)	missense	probably damaging	0.99
IGL01867:Akap6	APN	12	52,888,008 (GRCm38)	missense	probably damaging	1.00
IGL02025:Akap6	APN	12	53,140,335 (GRCm38)	missense	probably benign
IGL02041:Akap6	APN	12	53,140,653 (GRCm38)	missense	probably damaging	1.00
IGL02058:Akap6	APN	12	53,140,555 (GRCm38)	missense	probably damaging	1.00
IGL02194:Akap6	APN	12	52,886,823 (GRCm38)	missense	probably benign	0.00
IGL02226:Akap6	APN	12	53,010,467 (GRCm38)	splice site	probably benign
IGL02323:Akap6	APN	12	53,140,429 (GRCm38)	missense	probably benign	0.00
IGL02449:Akap6	APN	12	53,140,188 (GRCm38)	missense	probably damaging	1.00
IGL02475:Akap6	APN	12	53,139,494 (GRCm38)	missense	probably benign	0.03
IGL02546:Akap6	APN	12	52,880,738 (GRCm38)	missense	probably damaging	1.00
IGL02547:Akap6	APN	12	53,140,696 (GRCm38)	missense	probably damaging	1.00
IGL02588:Akap6	APN	12	52,886,499 (GRCm38)	nonsense	probably null
IGL02608:Akap6	APN	12	53,010,606 (GRCm38)	missense	probably benign	0.39
IGL02884:Akap6	APN	12	52,886,622 (GRCm38)	missense	probably benign	0.00
IGL02945:Akap6	APN	12	52,880,837 (GRCm38)	missense	probably damaging	1.00
IGL03029:Akap6	APN	12	52,886,412 (GRCm38)	missense	probably damaging	1.00
IGL03129:Akap6	APN	12	53,140,306 (GRCm38)	missense	probably damaging	1.00
R0133:Akap6	UTSW	12	53,139,471 (GRCm38)	nonsense	probably null
R0166:Akap6	UTSW	12	53,140,924 (GRCm38)	missense	probably benign	0.04
R0189:Akap6	UTSW	12	53,141,254 (GRCm38)	missense	probably benign	0.41
R0532:Akap6	UTSW	12	52,887,983 (GRCm38)	missense	probably benign	0.00
R0632:Akap6	UTSW	12	52,937,148 (GRCm38)	missense	probably damaging	1.00
R0666:Akap6	UTSW	12	52,911,808 (GRCm38)	missense	probably damaging	1.00
R0723:Akap6	UTSW	12	53,141,902 (GRCm38)	missense	probably damaging	1.00
R0763:Akap6	UTSW	12	53,142,214 (GRCm38)	missense	possibly damaging	0.93
R0785:Akap6	UTSW	12	52,886,622 (GRCm38)	missense	probably benign	0.00
R0879:Akap6	UTSW	12	52,880,799 (GRCm38)	missense	probably damaging	1.00
R0880:Akap6	UTSW	12	53,139,508 (GRCm38)	missense	possibly damaging	0.93
R1033:Akap6	UTSW	12	53,069,222 (GRCm38)	missense	probably damaging	0.97
R1055:Akap6	UTSW	12	52,880,672 (GRCm38)	nonsense	probably null
R1199:Akap6	UTSW	12	52,796,190 (GRCm38)	missense	probably damaging	1.00
R1295:Akap6	UTSW	12	52,887,029 (GRCm38)	missense	probably damaging	1.00
R1389:Akap6	UTSW	12	53,139,520 (GRCm38)	missense	probably benign	0.15
R1483:Akap6	UTSW	12	52,796,087 (GRCm38)	missense	probably damaging	1.00
R1512:Akap6	UTSW	12	52,937,154 (GRCm38)	missense	probably damaging	1.00
R1648:Akap6	UTSW	12	53,142,006 (GRCm38)	nonsense	probably null
R1791:Akap6	UTSW	12	53,069,125 (GRCm38)	missense	probably damaging	1.00
R1888:Akap6	UTSW	12	53,142,175 (GRCm38)	missense	possibly damaging	0.88
R1888:Akap6	UTSW	12	53,142,175 (GRCm38)	missense	possibly damaging	0.88
R1891:Akap6	UTSW	12	53,142,175 (GRCm38)	missense	possibly damaging	0.88
R1899:Akap6	UTSW	12	53,141,852 (GRCm38)	missense	possibly damaging	0.95
R1917:Akap6	UTSW	12	53,104,612 (GRCm38)	missense	probably benign	0.13
R1970:Akap6	UTSW	12	52,938,475 (GRCm38)	missense	probably damaging	0.96
R1987:Akap6	UTSW	12	53,140,795 (GRCm38)	missense	possibly damaging	0.78
R1988:Akap6	UTSW	12	53,140,795 (GRCm38)	missense	possibly damaging	0.78
R2153:Akap6	UTSW	12	53,141,404 (GRCm38)	missense	probably benign	0.03
R2567:Akap6	UTSW	12	52,938,373 (GRCm38)	missense	probably damaging	1.00
R2568:Akap6	UTSW	12	52,887,278 (GRCm38)	missense	possibly damaging	0.77
R3025:Akap6	UTSW	12	53,140,143 (GRCm38)	missense	probably benign
R3051:Akap6	UTSW	12	52,887,033 (GRCm38)	missense	probably damaging	1.00
R3195:Akap6	UTSW	12	53,072,457 (GRCm38)	nonsense	probably null
R3196:Akap6	UTSW	12	53,072,457 (GRCm38)	nonsense	probably null
R3426:Akap6	UTSW	12	52,888,034 (GRCm38)	missense	probably damaging	1.00
R3783:Akap6	UTSW	12	52,880,769 (GRCm38)	missense	probably damaging	1.00
R3934:Akap6	UTSW	12	53,140,444 (GRCm38)	missense	possibly damaging	0.92
R3936:Akap6	UTSW	12	53,140,444 (GRCm38)	missense	possibly damaging	0.92
R3967:Akap6	UTSW	12	53,141,453 (GRCm38)	missense	probably damaging	1.00
R3970:Akap6	UTSW	12	53,141,453 (GRCm38)	missense	probably damaging	1.00
R4042:Akap6	UTSW	12	53,139,379 (GRCm38)	critical splice acceptor site	probably null
R4095:Akap6	UTSW	12	53,139,462 (GRCm38)	missense	probably damaging	1.00
R4152:Akap6	UTSW	12	53,140,407 (GRCm38)	missense	probably benign	0.45
R4231:Akap6	UTSW	12	53,141,038 (GRCm38)	missense	probably damaging	1.00
R4232:Akap6	UTSW	12	53,139,671 (GRCm38)	missense	probably damaging	1.00
R4233:Akap6	UTSW	12	53,139,671 (GRCm38)	missense	probably damaging	1.00
R4234:Akap6	UTSW	12	53,139,671 (GRCm38)	missense	probably damaging	1.00
R4235:Akap6	UTSW	12	53,139,671 (GRCm38)	missense	probably damaging	1.00
R4236:Akap6	UTSW	12	53,139,671 (GRCm38)	missense	probably damaging	1.00
R4475:Akap6	UTSW	12	53,141,643 (GRCm38)	missense	probably benign	0.00
R4513:Akap6	UTSW	12	52,796,004 (GRCm38)	missense	probably benign	0.03
R4686:Akap6	UTSW	12	52,887,623 (GRCm38)	frame shift	probably null
R4724:Akap6	UTSW	12	52,795,885 (GRCm38)	missense	possibly damaging	0.80
R4782:Akap6	UTSW	12	52,887,623 (GRCm38)	frame shift	probably null
R4852:Akap6	UTSW	12	53,104,675 (GRCm38)	missense	probably damaging	1.00
R5024:Akap6	UTSW	12	53,142,562 (GRCm38)	missense	probably benign	0.01
R5116:Akap6	UTSW	12	53,141,515 (GRCm38)	missense	probably benign	0.01
R5164:Akap6	UTSW	12	53,142,466 (GRCm38)	missense	probably benign
R5225:Akap6	UTSW	12	52,886,546 (GRCm38)	missense	probably damaging	1.00
R5269:Akap6	UTSW	12	53,139,843 (GRCm38)	missense	probably damaging	0.99
R5352:Akap6	UTSW	12	52,796,097 (GRCm38)	missense	probably damaging	1.00
R5496:Akap6	UTSW	12	53,140,653 (GRCm38)	missense	possibly damaging	0.87
R5551:Akap6	UTSW	12	52,795,964 (GRCm38)	missense	probably damaging	1.00
R5997:Akap6	UTSW	12	52,937,233 (GRCm38)	critical splice donor site	probably null
R6137:Akap6	UTSW	12	53,140,354 (GRCm38)	missense	probably damaging	1.00
R6151:Akap6	UTSW	12	53,025,792 (GRCm38)	missense	probably damaging	1.00
R6169:Akap6	UTSW	12	53,142,358 (GRCm38)	missense	probably benign
R6307:Akap6	UTSW	12	53,141,568 (GRCm38)	missense	possibly damaging	0.85
R6351:Akap6	UTSW	12	53,142,025 (GRCm38)	missense	probably damaging	0.98
R6479:Akap6	UTSW	12	53,141,169 (GRCm38)	missense	probably damaging	1.00
R6502:Akap6	UTSW	12	53,140,215 (GRCm38)	missense	probably damaging	1.00
R6760:Akap6	UTSW	12	53,139,778 (GRCm38)	missense	probably damaging	1.00
R6778:Akap6	UTSW	12	53,025,816 (GRCm38)	missense	probably damaging	1.00
R6837:Akap6	UTSW	12	53,141,262 (GRCm38)	missense	probably damaging	1.00
R6896:Akap6	UTSW	12	52,887,494 (GRCm38)	missense	probably benign	0.06
R6917:Akap6	UTSW	12	53,069,168 (GRCm38)	missense	probably null	0.97
R6983:Akap6	UTSW	12	52,887,653 (GRCm38)	missense	probably damaging	1.00
R7142:Akap6	UTSW	12	52,887,364 (GRCm38)	missense	probably benign	0.02
R7143:Akap6	UTSW	12	52,887,364 (GRCm38)	missense	probably benign	0.02
R7216:Akap6	UTSW	12	53,140,457 (GRCm38)	missense	probably benign	0.02
R7297:Akap6	UTSW	12	52,887,364 (GRCm38)	missense	probably benign	0.02
R7356:Akap6	UTSW	12	52,911,864 (GRCm38)	missense	probably damaging	1.00
R7378:Akap6	UTSW	12	53,142,574 (GRCm38)	missense	probably benign	0.00
R7382:Akap6	UTSW	12	53,142,171 (GRCm38)	missense	probably benign	0.00
R7498:Akap6	UTSW	12	53,142,705 (GRCm38)	nonsense	probably null
R7542:Akap6	UTSW	12	53,069,234 (GRCm38)	missense	probably damaging	1.00
R7589:Akap6	UTSW	12	53,142,063 (GRCm38)	nonsense	probably null
R7676:Akap6	UTSW	12	52,886,850 (GRCm38)	missense	possibly damaging	0.94
R7814:Akap6	UTSW	12	53,140,961 (GRCm38)	missense	probably benign	0.28
R7971:Akap6	UTSW	12	53,139,795 (GRCm38)	missense	probably damaging	1.00
R8039:Akap6	UTSW	12	53,141,676 (GRCm38)	missense	probably benign	0.00
R8425:Akap6	UTSW	12	52,886,621 (GRCm38)	missense	probably benign	0.00
R8747:Akap6	UTSW	12	53,142,216 (GRCm38)	missense	probably benign	0.01
R8885:Akap6	UTSW	12	53,141,536 (GRCm38)	missense	probably benign
R8956:Akap6	UTSW	12	53,140,344 (GRCm38)	missense	probably benign	0.00
R8989:Akap6	UTSW	12	52,880,871 (GRCm38)	missense	probably damaging	1.00
R9014:Akap6	UTSW	12	53,139,620 (GRCm38)	missense	possibly damaging	0.60
R9031:Akap6	UTSW	12	53,142,048 (GRCm38)	missense	probably benign	0.36
R9216:Akap6	UTSW	12	52,880,885 (GRCm38)	missense	probably benign	0.05
R9220:Akap6	UTSW	12	53,140,449 (GRCm38)	missense	possibly damaging	0.49
R9243:Akap6	UTSW	12	53,141,252 (GRCm38)	missense	probably benign	0.08
R9286:Akap6	UTSW	12	53,072,471 (GRCm38)	missense	possibly damaging	0.90
R9347:Akap6	UTSW	12	53,069,111 (GRCm38)	missense	probably damaging	1.00
R9475:Akap6	UTSW	12	53,010,552 (GRCm38)	missense	probably damaging	1.00
R9509:Akap6	UTSW	12	53,142,238 (GRCm38)	missense	probably damaging	0.99
R9523:Akap6	UTSW	12	52,795,889 (GRCm38)	missense	probably benign	0.02
R9600:Akap6	UTSW	12	52,886,558 (GRCm38)	missense	probably benign	0.04
R9612:Akap6	UTSW	12	52,911,907 (GRCm38)	missense	probably damaging	1.00
R9627:Akap6	UTSW	12	53,104,630 (GRCm38)	missense
R9666:Akap6	UTSW	12	53,141,535 (GRCm38)	missense	probably benign
R9784:Akap6	UTSW	12	53,141,070 (GRCm38)	missense	probably damaging	1.00
X0062:Akap6	UTSW	12	53,142,361 (GRCm38)	missense	probably benign	0.43
Z1176:Akap6	UTSW	12	53,140,444 (GRCm38)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GGGCTGGACTACATCAAGAACGAAC -3'
(R):5'- GGGACCAAATTCCTTCCCAGTGAC -3'

Sequencing Primer
(F):5'- GTGGATAAGACCCAAACTTTCCTTG -3'
(R):5'- TCCCAGTGACACTTGAATCATCAG -3'

Posted On

2014-03-28