Mutagenetix > Incidental Mutation

Incidental Mutation 'R1464:Sdk2'

165347

Institutional Source

Beutler Lab

Gene Symbol

Sdk2

Ensembl Gene

ENSMUSG00000041592

Gene Name

sidekick cell adhesion molecule 2

Synonyms

4632412F08Rik, 5330435L01Rik

MMRRC Submission

039518-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.072) question?

Stock #

R1464 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

113667200-113957855 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 113720906 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Isoleucine at position 1341 (T1341I)

Ref Sequence

ENSEMBL: ENSMUSP00000038972 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041627]

AlphaFold

Q6V4S5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000041627
AA Change: T1341I

PolyPhen 2 Score 0.855 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000038972
Gene: ENSMUSG00000041592
AA Change: T1341I

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IGc2	43	102	4.67e-4	SMART
IG	123	208	6.07e-3	SMART
IG	225	309	1.4e-7	SMART
IGc2	325	391	6.21e-9	SMART
IGc2	418	486	8.57e-12	SMART
IG	506	591	2.37e-5	SMART
FN3	594	678	1.91e-7	SMART
FN3	694	780	2.42e-9	SMART
FN3	796	884	3.45e-5	SMART
FN3	899	981	2.36e-12	SMART
FN3	997	1084	1.64e-6	SMART
FN3	1101	1188	8.83e-12	SMART
FN3	1204	1289	3.62e-8	SMART
FN3	1305	1388	1.74e-10	SMART
FN3	1404	1489	8.23e-12	SMART
FN3	1506	1612	3.62e-8	SMART
FN3	1628	1713	1.15e-10	SMART
FN3	1728	1815	2.17e-11	SMART
FN3	1829	1913	5.04e-7	SMART
transmembrane domain	1935	1957	N/A	INTRINSIC
low complexity region	2138	2153	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125879

Coding Region Coverage

1x: 99.5%
3x: 98.0%
10x: 91.0%
20x: 72.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired interconnectvity between VG3 amacrine cells and W3B retinal ganglion cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
6030469F06Rik	A	G	12: 31,234,914 (GRCm39)		noncoding transcript	Het
Adamts8	T	A	9: 30,862,673 (GRCm39)	W86R	probably benign	Het
Adh1	A	G	3: 137,994,508 (GRCm39)		probably null	Het
Adipor2	A	T	6: 119,338,804 (GRCm39)	W150R	probably damaging	Het
Aff4	T	A	11: 53,263,351 (GRCm39)	S124T	probably damaging	Het
Ahnak	G	T	19: 8,982,260 (GRCm39)	K1181N	probably damaging	Het
Alkbh5	A	G	11: 60,429,873 (GRCm39)	I209V	probably benign	Het
Ankrd11	T	C	8: 123,619,463 (GRCm39)	E1442G	probably damaging	Het
Apba2	T	A	7: 64,345,297 (GRCm39)	D162E	probably benign	Het
Asic3	G	A	5: 24,618,819 (GRCm39)	G37E	probably damaging	Het
AU040320	A	T	4: 126,685,824 (GRCm39)	K133N	possibly damaging	Het
C1qtnf7	A	G	5: 43,766,481 (GRCm39)	S34G	probably benign	Het
Ccdc148	T	A	2: 58,796,374 (GRCm39)	R463*	probably null	Het
Ccdc148	T	C	2: 58,824,455 (GRCm39)	R329G	probably damaging	Het
Ccdc185	A	G	1: 182,576,263 (GRCm39)	I142T	probably benign	Het
Chrna10	G	A	7: 101,763,454 (GRCm39)	P114S	probably damaging	Het
Chst10	A	G	1: 38,904,772 (GRCm39)	I311T	probably damaging	Het
Cpne9	T	C	6: 113,271,698 (GRCm39)	Y353H	probably damaging	Het
Cubn	G	T	2: 13,330,099 (GRCm39)	A2594E	possibly damaging	Het
Cyp3a13	T	C	5: 137,903,827 (GRCm39)	N277S	possibly damaging	Het
Dctn4	A	G	18: 60,671,478 (GRCm39)	T117A	probably damaging	Het
Ddah1	A	T	3: 145,559,029 (GRCm39)	K96*	probably null	Het
Ddx5	A	C	11: 106,675,711 (GRCm39)	D326E	probably benign	Het
Dlg2	T	C	7: 91,617,406 (GRCm39)	S323P	probably damaging	Het
Dnaaf1	C	T	8: 120,306,049 (GRCm39)	H109Y	probably damaging	Het
Dnah8	C	A	17: 30,914,147 (GRCm39)	R1098S	possibly damaging	Het
Dnajc13	T	C	9: 104,091,366 (GRCm39)	T642A	probably benign	Het
Dnajc18	A	G	18: 35,813,900 (GRCm39)	S290P	possibly damaging	Het
Dscam	T	A	16: 96,602,453 (GRCm39)	H663L	possibly damaging	Het
Emc1	A	G	4: 139,098,248 (GRCm39)	N740S	probably damaging	Het
Enpp2	C	T	15: 54,727,208 (GRCm39)	G541D	probably damaging	Het
Fam234b	C	T	6: 135,205,490 (GRCm39)	T485I	probably benign	Het
Fbxl13	A	T	5: 21,688,989 (GRCm39)	I773K	probably benign	Het
Fmo4	A	G	1: 162,621,924 (GRCm39)	F429S	possibly damaging	Het
Frem1	T	C	4: 82,930,116 (GRCm39)	S277G	probably damaging	Het
Gaa	A	G	11: 119,163,810 (GRCm39)	I221V	probably benign	Het
Helz2	T	C	2: 180,881,447 (GRCm39)	E345G	probably damaging	Het
Ifna4	G	T	4: 88,760,237 (GRCm39)	R47I	probably damaging	Het
Igsf21	C	A	4: 139,761,836 (GRCm39)	A281S	probably benign	Het
Ikzf3	T	A	11: 98,407,731 (GRCm39)	I37L	probably benign	Het
Jag1	T	C	2: 136,957,568 (GRCm39)	E48G	probably damaging	Het
Jarid2	G	T	13: 45,001,857 (GRCm39)	V57F	probably damaging	Het
Kcnj4	A	G	15: 79,369,605 (GRCm39)	L125P	probably damaging	Het
Kif21b	A	G	1: 136,083,891 (GRCm39)	K713E	possibly damaging	Het
Layn	T	A	9: 50,968,886 (GRCm39)	S286C	probably damaging	Het
Lepr	T	A	4: 101,592,878 (GRCm39)	D164E	probably benign	Het
Macroh2a1	A	T	13: 56,230,949 (GRCm39)	S310T	probably damaging	Het
Map3k1	T	C	13: 111,892,405 (GRCm39)	H950R	possibly damaging	Het
Map4k5	C	A	12: 69,852,124 (GRCm39)	V801L	possibly damaging	Het
Mapkbp1	T	A	2: 119,851,742 (GRCm39)	S895T	probably benign	Het
Naca	T	A	10: 127,884,157 (GRCm39)	M2157K	probably damaging	Het
Nav2	T	C	7: 49,011,952 (GRCm39)	I61T	probably damaging	Het
Nkx2-5	C	A	17: 27,058,253 (GRCm39)	A234S	probably benign	Het
Nol8	G	A	13: 49,830,264 (GRCm39)	S1116N	probably benign	Het
Nppa	T	C	4: 148,085,304 (GRCm39)	S5P	probably benign	Het
Nup210	A	G	6: 91,030,551 (GRCm39)	V123A	possibly damaging	Het
Or13a21	G	T	7: 139,999,286 (GRCm39)	N133K	probably benign	Het
Osbpl11	A	G	16: 33,049,455 (GRCm39)	K604R	probably damaging	Het
Osbpl1a	C	T	18: 13,047,615 (GRCm39)	S113N	probably benign	Het
P2rx4	C	A	5: 122,852,602 (GRCm39)	P92Q	probably damaging	Het
Pde9a	A	T	17: 31,692,136 (GRCm39)	Q148L	probably benign	Het
Phf21b	T	A	15: 84,689,160 (GRCm39)	H122L	probably damaging	Het
Pik3ca	T	A	3: 32,515,990 (GRCm39)	F977I	probably damaging	Het
Potefam1	A	G	2: 111,055,748 (GRCm39)		probably null	Het
Pp2d1	T	G	17: 53,823,015 (GRCm39)	K17T	possibly damaging	Het
Ppp4r2	A	G	6: 100,843,527 (GRCm39)	E415G	probably damaging	Het
Pramel19	T	A	4: 101,798,503 (GRCm39)	L158Q	probably damaging	Het
Prkg1	A	G	19: 30,556,270 (GRCm39)	S559P	probably damaging	Het
Prss45	A	T	9: 110,670,019 (GRCm39)	Y276F	possibly damaging	Het
Ptk7	G	T	17: 46,883,517 (GRCm39)	N849K	probably damaging	Het
Rnf121	A	G	7: 101,680,782 (GRCm39)	I125T	possibly damaging	Het
Rnf17	A	G	14: 56,699,368 (GRCm39)	N502S	probably damaging	Het
Sap25	T	A	5: 137,640,622 (GRCm39)	Y167*	probably null	Het
Sgcb	A	G	5: 73,792,896 (GRCm39)	V302A	probably benign	Het
Skor1	T	A	9: 63,047,393 (GRCm39)	M865L	possibly damaging	Het
Slc35g1	C	A	19: 38,391,665 (GRCm39)	L316I	probably benign	Het
Slco1a8	C	T	6: 141,938,243 (GRCm39)	W225*	probably null	Het
Spint4	T	A	2: 164,540,568 (GRCm39)	L33H	probably damaging	Het
Sptlc3	A	T	2: 139,389,154 (GRCm39)	D178V	probably benign	Het
Tbc1d2	T	A	4: 46,606,491 (GRCm39)	Y818F	possibly damaging	Het
Tbc1d24	A	T	17: 24,400,197 (GRCm39)		probably null	Het
Teddm2	C	T	1: 153,726,277 (GRCm39)	W146*	probably null	Het
Ttn	T	A	2: 76,589,338 (GRCm39)	D12948V	probably damaging	Het
Txndc8	T	C	4: 58,000,274 (GRCm39)	T102A	probably damaging	Het
Uxs1	G	A	1: 43,804,076 (GRCm39)	Q280*	probably null	Het
Vmn1r167	T	C	7: 23,204,681 (GRCm39)	T112A	possibly damaging	Het
Vmn1r195	A	T	13: 22,463,348 (GRCm39)	I273L	probably benign	Het
Vmn1r28	T	A	6: 58,242,217 (GRCm39)	M20K	probably benign	Het
Vmn1r53	G	A	6: 90,200,914 (GRCm39)	L137F	probably benign	Het
Vps13b	C	T	15: 35,709,630 (GRCm39)	A1859V	probably benign	Het
Vwa5b2	A	G	16: 20,415,019 (GRCm39)	H347R	probably benign	Het
Wnk2	G	A	13: 49,235,451 (GRCm39)	P655S	probably damaging	Het
Zan	T	G	5: 137,418,191 (GRCm39)	D2969A	unknown	Het
Zbtb24	A	G	10: 41,331,075 (GRCm39)	H334R	probably damaging	Het
Zfp108	A	G	7: 23,959,973 (GRCm39)	D188G	probably benign	Het
Zfp784	A	T	7: 5,038,800 (GRCm39)	C253S	possibly damaging	Het
Zfr	T	G	15: 12,146,458 (GRCm39)	C336W	probably damaging	Het

Other mutations in Sdk2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00972:Sdk2	APN	11	113,745,210 (GRCm39)	missense	possibly damaging	0.86
IGL01063:Sdk2	APN	11	113,721,668 (GRCm39)	missense	probably damaging	1.00
IGL01291:Sdk2	APN	11	113,733,906 (GRCm39)	missense	probably benign
IGL01316:Sdk2	APN	11	113,758,791 (GRCm39)	missense	probably benign	0.09
IGL01614:Sdk2	APN	11	113,684,684 (GRCm39)	missense	probably damaging	1.00
IGL01998:Sdk2	APN	11	113,729,358 (GRCm39)	missense	probably damaging	0.98
IGL02014:Sdk2	APN	11	113,729,320 (GRCm39)	missense	probably damaging	1.00
IGL02095:Sdk2	APN	11	113,725,656 (GRCm39)	missense	probably damaging	1.00
IGL02115:Sdk2	APN	11	113,725,639 (GRCm39)	splice site	probably benign
IGL02543:Sdk2	APN	11	113,759,747 (GRCm39)	missense	possibly damaging	0.90
IGL02976:Sdk2	APN	11	113,742,668 (GRCm39)	missense	probably damaging	1.00
IGL03001:Sdk2	APN	11	113,712,452 (GRCm39)	missense	probably benign	0.00
IGL03122:Sdk2	APN	11	113,732,894 (GRCm39)	missense	probably damaging	1.00
IGL03183:Sdk2	APN	11	113,741,810 (GRCm39)	missense	probably benign	0.19
IGL03222:Sdk2	APN	11	113,729,257 (GRCm39)	missense	probably benign	0.01
IGL03310:Sdk2	APN	11	113,684,151 (GRCm39)	missense	possibly damaging	0.77
Curtailed	UTSW	11	113,742,626 (GRCm39)	missense	probably damaging	1.00
Trimmed	UTSW	11	113,747,522 (GRCm39)	nonsense	probably null
ANU05:Sdk2	UTSW	11	113,733,906 (GRCm39)	missense	probably benign
BB008:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
BB018:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
R0008:Sdk2	UTSW	11	113,747,581 (GRCm39)	missense	probably damaging	1.00
R0008:Sdk2	UTSW	11	113,747,581 (GRCm39)	missense	probably damaging	1.00
R0088:Sdk2	UTSW	11	113,717,912 (GRCm39)	missense	possibly damaging	0.74
R0096:Sdk2	UTSW	11	113,793,970 (GRCm39)	splice site	probably benign
R0386:Sdk2	UTSW	11	113,784,290 (GRCm39)	missense	probably damaging	0.96
R0396:Sdk2	UTSW	11	113,720,793 (GRCm39)	missense	probably benign	0.04
R0409:Sdk2	UTSW	11	113,741,717 (GRCm39)	splice site	probably benign
R0416:Sdk2	UTSW	11	113,694,029 (GRCm39)	missense	probably damaging	1.00
R0456:Sdk2	UTSW	11	113,682,292 (GRCm39)	missense	possibly damaging	0.93
R0544:Sdk2	UTSW	11	113,671,836 (GRCm39)	missense	probably damaging	1.00
R0691:Sdk2	UTSW	11	113,685,746 (GRCm39)	splice site	probably null
R0711:Sdk2	UTSW	11	113,793,970 (GRCm39)	splice site	probably benign
R0717:Sdk2	UTSW	11	113,723,152 (GRCm39)	missense	probably damaging	1.00
R0780:Sdk2	UTSW	11	113,784,334 (GRCm39)	missense	probably benign	0.07
R0831:Sdk2	UTSW	11	113,723,084 (GRCm39)	missense	probably damaging	0.96
R0853:Sdk2	UTSW	11	113,712,241 (GRCm39)	missense	probably benign	0.00
R0865:Sdk2	UTSW	11	113,741,748 (GRCm39)	missense	probably benign	0.12
R0930:Sdk2	UTSW	11	113,729,271 (GRCm39)	missense	probably benign	0.01
R0964:Sdk2	UTSW	11	113,697,243 (GRCm39)	splice site	probably benign
R1051:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1052:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1054:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1055:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1077:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1079:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1115:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1186:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1187:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1337:Sdk2	UTSW	11	113,723,157 (GRCm39)	missense	possibly damaging	0.79
R1430:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1433:Sdk2	UTSW	11	113,685,871 (GRCm39)	missense	probably damaging	0.99
R1464:Sdk2	UTSW	11	113,720,906 (GRCm39)	missense	possibly damaging	0.86
R1497:Sdk2	UTSW	11	113,784,401 (GRCm39)	splice site	probably benign
R1514:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1529:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1596:Sdk2	UTSW	11	113,729,435 (GRCm39)	splice site	probably benign
R1680:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1680:Sdk2	UTSW	11	113,682,262 (GRCm39)	missense	possibly damaging	0.47
R1770:Sdk2	UTSW	11	113,684,567 (GRCm39)	missense	probably benign	0.05
R1858:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1866:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1874:Sdk2	UTSW	11	113,725,782 (GRCm39)	missense	probably benign	0.00
R1899:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1905:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1907:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1913:Sdk2	UTSW	11	113,747,552 (GRCm39)	missense	possibly damaging	0.77
R1964:Sdk2	UTSW	11	113,671,843 (GRCm39)	nonsense	probably null
R2055:Sdk2	UTSW	11	113,741,780 (GRCm39)	missense	probably damaging	1.00
R2059:Sdk2	UTSW	11	113,745,158 (GRCm39)	missense	probably damaging	1.00
R2093:Sdk2	UTSW	11	113,833,948 (GRCm39)	missense	probably damaging	1.00
R2256:Sdk2	UTSW	11	113,721,620 (GRCm39)	missense	probably benign	0.44
R3720:Sdk2	UTSW	11	113,691,070 (GRCm39)	missense	probably damaging	1.00
R3795:Sdk2	UTSW	11	113,747,522 (GRCm39)	nonsense	probably null
R4037:Sdk2	UTSW	11	113,685,881 (GRCm39)	missense	probably damaging	1.00
R4171:Sdk2	UTSW	11	113,757,815 (GRCm39)	splice site	probably null
R4717:Sdk2	UTSW	11	113,745,195 (GRCm39)	missense	probably damaging	0.96
R4758:Sdk2	UTSW	11	113,717,880 (GRCm39)	missense	possibly damaging	0.87
R4857:Sdk2	UTSW	11	113,712,208 (GRCm39)	nonsense	probably null
R4924:Sdk2	UTSW	11	113,748,584 (GRCm39)	missense	probably damaging	1.00
R5015:Sdk2	UTSW	11	113,684,587 (GRCm39)	missense	probably damaging	1.00
R5171:Sdk2	UTSW	11	113,741,808 (GRCm39)	missense	probably benign	0.01
R5239:Sdk2	UTSW	11	113,758,859 (GRCm39)	missense	probably damaging	1.00
R5243:Sdk2	UTSW	11	113,715,912 (GRCm39)	missense	possibly damaging	0.76
R5279:Sdk2	UTSW	11	113,757,857 (GRCm39)	missense	probably benign	0.31
R5535:Sdk2	UTSW	11	113,833,984 (GRCm39)	missense	possibly damaging	0.80
R5634:Sdk2	UTSW	11	113,742,540 (GRCm39)	missense	probably damaging	1.00
R5637:Sdk2	UTSW	11	113,724,005 (GRCm39)	missense	probably damaging	1.00
R5726:Sdk2	UTSW	11	113,742,626 (GRCm39)	missense	probably damaging	1.00
R5793:Sdk2	UTSW	11	113,759,778 (GRCm39)	missense	possibly damaging	0.46
R5798:Sdk2	UTSW	11	113,717,942 (GRCm39)	missense	probably damaging	1.00
R5834:Sdk2	UTSW	11	113,745,099 (GRCm39)	missense	probably damaging	1.00
R5863:Sdk2	UTSW	11	113,725,810 (GRCm39)	missense	probably damaging	0.98
R5869:Sdk2	UTSW	11	113,742,708 (GRCm39)	missense	probably damaging	0.96
R5875:Sdk2	UTSW	11	113,720,885 (GRCm39)	missense	probably benign	0.00
R5953:Sdk2	UTSW	11	113,684,570 (GRCm39)	missense	probably damaging	1.00
R5991:Sdk2	UTSW	11	113,834,080 (GRCm39)	missense	probably damaging	0.97
R6018:Sdk2	UTSW	11	113,720,889 (GRCm39)	missense	probably benign	0.00
R6116:Sdk2	UTSW	11	113,745,190 (GRCm39)	missense	probably damaging	0.99
R6328:Sdk2	UTSW	11	113,684,581 (GRCm39)	missense	probably damaging	1.00
R6348:Sdk2	UTSW	11	113,784,334 (GRCm39)	missense	probably benign	0.07
R6383:Sdk2	UTSW	11	113,723,091 (GRCm39)	missense	probably damaging	1.00
R6824:Sdk2	UTSW	11	113,758,760 (GRCm39)	missense	probably benign	0.43
R6835:Sdk2	UTSW	11	113,720,874 (GRCm39)	missense	probably damaging	0.98
R6853:Sdk2	UTSW	11	113,671,755 (GRCm39)	missense	probably damaging	0.99
R6912:Sdk2	UTSW	11	113,793,946 (GRCm39)	missense	probably benign	0.03
R7000:Sdk2	UTSW	11	113,693,995 (GRCm39)	missense	probably damaging	1.00
R7099:Sdk2	UTSW	11	113,725,731 (GRCm39)	missense	probably damaging	0.98
R7102:Sdk2	UTSW	11	113,733,516 (GRCm39)	nonsense	probably null
R7177:Sdk2	UTSW	11	113,720,795 (GRCm39)	missense	possibly damaging	0.91
R7381:Sdk2	UTSW	11	113,729,315 (GRCm39)	missense	probably damaging	0.98
R7412:Sdk2	UTSW	11	113,758,909 (GRCm39)	splice site	probably null
R7504:Sdk2	UTSW	11	113,758,793 (GRCm39)	missense	possibly damaging	0.50
R7552:Sdk2	UTSW	11	113,764,039 (GRCm39)	missense	possibly damaging	0.63
R7604:Sdk2	UTSW	11	113,720,795 (GRCm39)	missense	possibly damaging	0.91
R7647:Sdk2	UTSW	11	113,684,563 (GRCm39)	missense	probably damaging	1.00
R7897:Sdk2	UTSW	11	113,764,027 (GRCm39)	missense	possibly damaging	0.50
R7931:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
R7998:Sdk2	UTSW	11	113,750,764 (GRCm39)	missense	probably benign	0.18
R8052:Sdk2	UTSW	11	113,745,177 (GRCm39)	missense	probably damaging	1.00
R8053:Sdk2	UTSW	11	113,745,177 (GRCm39)	missense	probably damaging	1.00
R8084:Sdk2	UTSW	11	113,717,915 (GRCm39)	missense	possibly damaging	0.67
R8136:Sdk2	UTSW	11	113,742,539 (GRCm39)	missense	probably damaging	1.00
R8151:Sdk2	UTSW	11	113,763,683 (GRCm39)	missense	possibly damaging	0.84
R8394:Sdk2	UTSW	11	113,729,542 (GRCm39)	missense	probably benign
R8715:Sdk2	UTSW	11	113,671,728 (GRCm39)	missense	probably damaging	1.00
R8774:Sdk2	UTSW	11	113,730,169 (GRCm39)	missense	probably damaging	1.00
R8774-TAIL:Sdk2	UTSW	11	113,730,169 (GRCm39)	missense	probably damaging	1.00
R8804:Sdk2	UTSW	11	113,763,978 (GRCm39)	nonsense	probably null
R9136:Sdk2	UTSW	11	113,697,203 (GRCm39)	missense	probably damaging	1.00
R9147:Sdk2	UTSW	11	113,714,226 (GRCm39)	missense	probably benign	0.18
R9300:Sdk2	UTSW	11	113,715,856 (GRCm39)	missense	possibly damaging	0.63
R9354:Sdk2	UTSW	11	113,725,757 (GRCm39)	missense	probably benign	0.00
R9450:Sdk2	UTSW	11	113,697,105 (GRCm39)	missense	probably benign
R9462:Sdk2	UTSW	11	113,760,744 (GRCm39)	missense	possibly damaging	0.56
R9616:Sdk2	UTSW	11	113,691,061 (GRCm39)	missense	probably benign	0.05
R9678:Sdk2	UTSW	11	113,685,789 (GRCm39)	nonsense	probably null
RF002:Sdk2	UTSW	11	113,776,078 (GRCm39)	missense	probably benign	0.00
V1662:Sdk2	UTSW	11	113,725,734 (GRCm39)	missense	probably damaging	1.00
Z1176:Sdk2	UTSW	11	113,742,662 (GRCm39)	missense	probably damaging	0.97
Z1176:Sdk2	UTSW	11	113,730,148 (GRCm39)	missense	probably benign	0.41
Z1177:Sdk2	UTSW	11	113,750,782 (GRCm39)	missense	probably benign
Z1177:Sdk2	UTSW	11	113,730,146 (GRCm39)	missense	probably damaging	1.00
Z1177:Sdk2	UTSW	11	113,729,485 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- GACATGGCATGATCCCTTAGTGACC -3'
(R):5'- TGGACATCAAGCCCATTGGACAAG -3'

Sequencing Primer
(F):5'- ATGATCCCTTAGTGACCTTGAC -3'
(R):5'- AAAGCACCGGGCTATTGC -3'

Posted On

2014-03-28