Mutagenetix > Incidental Mutation

Incidental Mutation 'R1470:Dnah9'

165841

Institutional Source

Beutler Lab

Gene Symbol

Dnah9

Ensembl Gene

ENSMUSG00000056752

Gene Name

dynein, axonemal, heavy chain 9

Synonyms

D11Ertd686e, Dnahc9

MMRRC Submission

039523-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.294) question?

Stock #

R1470 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

65831282-66168551 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 65927822 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 3230 (N3230S)

Ref Sequence

ENSEMBL: ENSMUSP00000079494 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080665] [ENSMUST00000130739]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000080665
AA Change: N3230S

PolyPhen 2 Score 0.111 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000079494
Gene: ENSMUSG00000056752
AA Change: N3230S

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	209	787	3.6e-164	PFAM
coiled coil region	788	820	N/A	INTRINSIC
low complexity region	1228	1240	N/A	INTRINSIC
Pfam:DHC_N2	1290	1699	1.4e-134	PFAM
AAA	1863	1999	4.9e-1	SMART
AAA	2141	2341	1.99e0	SMART
AAA	2468	2614	6.75e-1	SMART
Pfam:AAA_8	2786	3053	1.1e-165	PFAM
Pfam:MT	3065	3408	7.2e-208	PFAM
Pfam:AAA_9	3430	3652	3.2e-87	PFAM
Pfam:Dynein_heavy	3786	4482	1e-241	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000130739
AA Change: N46S

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000116227
Gene: ENSMUSG00000056752
AA Change: N46S

Domain	Start	End	E-Value	Type
Pfam:MT	1	172	7e-100	PFAM
Pfam:AAA_9	179	279	7.2e-59	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000152386
AA Change: N779S

SMART Domains

Protein: ENSMUSP00000116499
Gene: ENSMUSG00000056752
AA Change: N779S

Domain	Start	End	E-Value	Type
Pfam:AAA_7	1	258	3e-155	PFAM
Pfam:AAA_8	336	603	3.9e-166	PFAM
Pfam:MT	615	958	2.3e-208	PFAM
Pfam:AAA_9	980	1202	1.1e-87	PFAM
Pfam:Dynein_heavy	1336	1514	2.4e-52	PFAM
Pfam:Dynein_heavy	1508	1956	8.6e-155	PFAM

Meta Mutation Damage Score

0.0720

Coding Region Coverage

1x: 99.7%
3x: 98.4%
10x: 90.6%
20x: 68.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 123 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aak1	T	A	6: 86,967,355 (GRCm38)	S749T	unknown	Het
Abcb4	A	T	5: 8,940,968 (GRCm38)	I843F	probably damaging	Het
Actr8	T	A	14: 29,986,969 (GRCm38)	H244Q	possibly damaging	Het
Adgrv1	A	G	13: 81,382,298 (GRCm38)	Y5886H	probably benign	Het
Agk	T	A	6: 40,386,817 (GRCm38)	W244R	probably damaging	Het
Ankrd11	C	A	8: 122,899,724 (GRCm38)	V161L	probably damaging	Het
Arap3	T	C	18: 37,989,196 (GRCm38)		probably null	Het
Armc3	A	G	2: 19,238,736 (GRCm38)	M88V	probably benign	Het
Atp13a5	G	T	16: 29,349,015 (GRCm38)	P109T	probably benign	Het
Avpr1b	T	A	1: 131,600,585 (GRCm38)	V282D	probably damaging	Het
Baz2b	T	C	2: 59,978,546 (GRCm38)	K120E	possibly damaging	Het
Bltp1	T	C	3: 36,998,331 (GRCm38)	M3060T	probably benign	Het
Cacng6	G	A	7: 3,424,888 (GRCm38)	C76Y	probably damaging	Het
Cactin	G	T	10: 81,323,151 (GRCm38)	E279*	probably null	Het
Car9	A	G	4: 43,510,222 (GRCm38)	Y268C	probably damaging	Het
Ccdc146	T	A	5: 21,319,566 (GRCm38)	I263F	probably damaging	Het
Cdh16	T	G	8: 104,618,371 (GRCm38)	S429R	probably benign	Het
Cep250	A	G	2: 155,991,075 (GRCm38)	E1639G	probably damaging	Het
Ces1d	A	T	8: 93,195,021 (GRCm38)	V38D	possibly damaging	Het
Chd1	A	T	17: 15,726,283 (GRCm38)	Q97L	possibly damaging	Het
Ciita	G	A	16: 10,514,468 (GRCm38)	D898N	possibly damaging	Het
Clstn1	A	G	4: 149,634,722 (GRCm38)	N336S	possibly damaging	Het
Cntnap5a	A	G	1: 116,259,519 (GRCm38)	D607G	probably damaging	Het
Col1a2	G	A	6: 4,518,822 (GRCm38)		probably benign	Het
Col20a1	C	T	2: 180,994,960 (GRCm38)	H245Y	probably benign	Het
Coq8b	A	T	7: 27,252,309 (GRCm38)	T399S	probably benign	Het
Cpn2	A	G	16: 30,260,185 (GRCm38)	S233P	probably benign	Het
Cryz	G	A	3: 154,606,476 (GRCm38)	G70D	probably damaging	Het
Def6	T	A	17: 28,225,982 (GRCm38)	D451E	possibly damaging	Het
Dnah8	T	A	17: 30,747,277 (GRCm38)	C2480*	probably null	Het
Dyrk4	G	T	6: 126,916,374 (GRCm38)	S15*	probably null	Het
Erc1	T	C	6: 119,694,602 (GRCm38)	R917G	probably damaging	Het
Frem3	G	T	8: 80,611,191 (GRCm38)	V38L	probably benign	Het
Gas2l3	T	C	10: 89,413,934 (GRCm38)	I441V	probably benign	Het
Gm14393	T	A	2: 175,063,981 (GRCm38)	Y6F	probably damaging	Het
Gm1527	A	G	3: 28,915,268 (GRCm38)	K256E	possibly damaging	Het
Gm21905	G	T	5: 67,946,397 (GRCm38)		probably benign	Het
Gtf2ird1	T	A	5: 134,395,802 (GRCm38)		probably null	Het
Hmces	C	A	6: 87,936,139 (GRCm38)	T292K	probably benign	Het
Hpse2	G	A	19: 43,388,253 (GRCm38)	S20L	probably benign	Het
Ift70b	G	T	2: 75,937,811 (GRCm38)	S199R	probably benign	Het
Ikbke	A	T	1: 131,276,487 (GRCm38)	V23E	probably null	Het
Ino80	A	T	2: 119,379,649 (GRCm38)	V1387E	probably damaging	Het
Islr	G	T	9: 58,157,306 (GRCm38)	A306D	probably damaging	Het
Jakmip1	G	A	5: 37,100,838 (GRCm38)	G276D	probably damaging	Het
Jchain	A	G	5: 88,526,120 (GRCm38)	V55A	probably benign	Het
Kalrn	T	C	16: 34,187,471 (GRCm38)	K1350E	probably damaging	Het
Kansl1l	T	C	1: 66,801,997 (GRCm38)	Q48R	possibly damaging	Het
Kmt5a	T	C	5: 124,447,271 (GRCm38)	L23P	probably damaging	Het
Lrba	C	T	3: 86,737,142 (GRCm38)	H381Y	probably damaging	Het
Lrrc32	T	C	7: 98,499,357 (GRCm38)	V448A	probably benign	Het
Mapkbp1	T	C	2: 120,017,820 (GRCm38)	M617T	probably damaging	Het
Mfap1a	T	C	2: 121,502,801 (GRCm38)	M50V	probably benign	Het
Mgam	G	T	6: 40,759,128 (GRCm38)	A854S	probably damaging	Het
Myo18b	C	A	5: 112,693,033 (GRCm38)	R2298L	probably damaging	Het
Myo1h	T	A	5: 114,319,704 (GRCm38)	M92K	probably damaging	Het
Nlrp2	T	A	7: 5,300,951 (GRCm38)	T192S	probably benign	Het
Nr2f1	A	T	13: 78,198,165 (GRCm38)	Y137N	possibly damaging	Het
Nup98	T	A	7: 102,147,306 (GRCm38)	D841V	probably damaging	Het
Nvl	A	G	1: 181,139,262 (GRCm38)	V59A	probably damaging	Het
Ogdhl	C	A	14: 32,346,788 (GRCm38)	N948K	probably damaging	Het
Or11g27	T	C	14: 50,533,702 (GRCm38)	S97P	possibly damaging	Het
Or12j3	A	G	7: 140,373,113 (GRCm38)	S166P	probably benign	Het
Or13a24	A	G	7: 140,574,749 (GRCm38)	T199A	probably benign	Het
Or51g1	A	C	7: 102,984,323 (GRCm38)	Y280*	probably null	Het
Osgin1	G	A	8: 119,444,965 (GRCm38)	R166H	probably damaging	Het
Palb2	A	T	7: 122,107,523 (GRCm38)	F741I	probably benign	Het
Palb2	G	T	7: 122,107,524 (GRCm38)	Y740*	probably null	Het
Parvb	G	A	15: 84,271,308 (GRCm38)	D65N	probably benign	Het
Parvb	G	A	15: 84,271,252 (GRCm38)	G46D	probably damaging	Het
Pcsk2	A	T	2: 143,546,518 (GRCm38)	K10*	probably null	Het
Pde3a	C	T	6: 141,466,206 (GRCm38)	A502V	probably benign	Het
Pfas	T	C	11: 68,991,359 (GRCm38)	I893V	probably benign	Het
Pla2g4a	A	T	1: 149,840,720 (GRCm38)	D663E	probably damaging	Het
Prickle2	G	A	6: 92,458,602 (GRCm38)	P6L	probably damaging	Het
Prx	T	A	7: 27,517,601 (GRCm38)	M648K	probably benign	Het
Ptpn21	T	C	12: 98,688,476 (GRCm38)	N744S	probably benign	Het
Ptprq	C	T	10: 107,718,574 (GRCm38)	V97M	probably damaging	Het
Pvr	T	C	7: 19,918,624 (GRCm38)	E122G	possibly damaging	Het
Racgap1	T	C	15: 99,639,775 (GRCm38)	K15E	probably damaging	Het
Rock1	C	T	18: 10,136,091 (GRCm38)		probably null	Het
Rorc	T	A	3: 94,397,302 (GRCm38)	Y331*	probably null	Het
Rpl37	T	C	15: 5,118,614 (GRCm38)	V91A	probably benign	Het
Rrp36	T	A	17: 46,672,380 (GRCm38)	K103*	probably null	Het
Ryr3	T	A	2: 112,653,007 (GRCm38)	M4142L	probably benign	Het
Sash1	A	T	10: 8,789,593 (GRCm38)	L125H	probably damaging	Het
Scn5a	T	C	9: 119,536,475 (GRCm38)	M369V	possibly damaging	Het
Sfi1	C	CT	11: 3,146,255 (GRCm38)		probably null	Het
Sfi1	TCGC	TC	11: 3,146,254 (GRCm38)		probably null	Het
Siglec1	A	T	2: 131,070,387 (GRCm38)	N1678K	probably benign	Het
Slc15a5	A	T	6: 138,072,994 (GRCm38)	V141E	probably benign	Het
Slc8a3	A	T	12: 81,199,710 (GRCm38)	H856Q	probably benign	Het
Sptlc2	T	A	12: 87,355,640 (GRCm38)	M171L	probably benign	Het
Srcap	T	A	7: 127,559,727 (GRCm38)		probably benign	Het
St6gal2	A	G	17: 55,490,943 (GRCm38)	D310G	probably damaging	Het
Susd2	T	A	10: 75,638,054 (GRCm38)	D689V	probably damaging	Het
Suz12	A	T	11: 80,019,732 (GRCm38)	E303V	possibly damaging	Het
Taldo1	C	A	7: 141,398,587 (GRCm38)	T150K	probably damaging	Het
Tg	T	A	15: 66,849,463 (GRCm38)	F274I	possibly damaging	Het
Tmem151b	T	C	17: 45,545,737 (GRCm38)	D259G	probably damaging	Het
Tmem179	G	T	12: 112,501,854 (GRCm38)	H64Q	probably benign	Het
Tmem236	A	G	2: 14,218,921 (GRCm38)	T174A	probably benign	Het
Tnc	A	T	4: 63,966,574 (GRCm38)	N1821K	probably damaging	Het
Tnfrsf11a	A	G	1: 105,825,048 (GRCm38)	N261S	probably damaging	Het
Trank1	C	A	9: 111,343,232 (GRCm38)	F96L	possibly damaging	Het
Trim56	T	A	5: 137,113,163 (GRCm38)	I500F	probably damaging	Het
Ttll5	A	G	12: 85,879,394 (GRCm38)	I321V	possibly damaging	Het
Ttn	C	A	2: 76,778,023 (GRCm38)	W17852L	probably damaging	Het
Twnk	G	A	19: 45,009,381 (GRCm38)	V450M	probably damaging	Het
Uba52	A	G	8: 70,509,556 (GRCm38)	I127T	possibly damaging	Het
Ubr4	T	A	4: 139,421,226 (GRCm38)		probably null	Het
Uggt1	A	T	1: 36,176,796 (GRCm38)	M130K	probably benign	Het
Ulk4	T	A	9: 121,081,656 (GRCm38)	T1101S	probably benign	Het
Urb1	A	G	16: 90,752,014 (GRCm38)	S2269P	probably benign	Het
Ush2a	G	T	1: 188,400,206 (GRCm38)	R875L	probably benign	Het
Usp9y	T	A	Y: 1,332,471 (GRCm38)	H1624L	probably benign	Het
Vipr1	T	C	9: 121,665,520 (GRCm38)	L308S	possibly damaging	Het
Xdh	T	G	17: 73,891,112 (GRCm38)	K1260T	probably damaging	Het
Yipf4	A	G	17: 74,493,968 (GRCm38)	I94V	probably benign	Het
Zfhx4	A	G	3: 5,413,146 (GRCm38)	*3582W	probably null	Het
Zfp58	T	C	13: 67,492,025 (GRCm38)	N116D	possibly damaging	Het
Zfp750	C	A	11: 121,511,993 (GRCm38)	R643L	probably benign	Het
Znfx1	A	G	2: 167,042,587 (GRCm38)	V51A	possibly damaging	Het

Other mutations in Dnah9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00696:Dnah9	APN	11	65,841,238 (GRCm38)	splice site	probably benign
IGL00805:Dnah9	APN	11	65,881,695 (GRCm38)	missense	probably benign	0.00
IGL00826:Dnah9	APN	11	65,989,942 (GRCm38)	missense	probably damaging	1.00
IGL01108:Dnah9	APN	11	65,849,980 (GRCm38)	missense	possibly damaging	0.93
IGL01152:Dnah9	APN	11	66,072,056 (GRCm38)	missense	probably damaging	1.00
IGL01353:Dnah9	APN	11	66,080,571 (GRCm38)	missense	probably damaging	1.00
IGL01364:Dnah9	APN	11	66,155,459 (GRCm38)	missense	probably damaging	1.00
IGL01479:Dnah9	APN	11	65,955,717 (GRCm38)	missense	probably benign	0.14
IGL01537:Dnah9	APN	11	65,947,680 (GRCm38)	missense	probably benign
IGL01565:Dnah9	APN	11	66,033,829 (GRCm38)	missense	possibly damaging	0.95
IGL01597:Dnah9	APN	11	66,118,830 (GRCm38)	missense	probably damaging	1.00
IGL01619:Dnah9	APN	11	65,831,615 (GRCm38)	nonsense	probably null
IGL01625:Dnah9	APN	11	66,044,645 (GRCm38)	missense	probably damaging	1.00
IGL01803:Dnah9	APN	11	66,118,829 (GRCm38)	missense	probably damaging	1.00
IGL01819:Dnah9	APN	11	66,108,126 (GRCm38)	missense	probably benign	0.33
IGL01896:Dnah9	APN	11	66,130,666 (GRCm38)	missense	possibly damaging	0.89
IGL01922:Dnah9	APN	11	66,075,034 (GRCm38)	splice site	probably benign
IGL01923:Dnah9	APN	11	66,125,235 (GRCm38)	splice site	probably benign
IGL02059:Dnah9	APN	11	66,072,958 (GRCm38)	missense	probably damaging	1.00
IGL02068:Dnah9	APN	11	66,061,045 (GRCm38)	missense	probably damaging	1.00
IGL02135:Dnah9	APN	11	66,117,492 (GRCm38)	missense	possibly damaging	0.63
IGL02146:Dnah9	APN	11	65,927,700 (GRCm38)	missense	probably damaging	1.00
IGL02264:Dnah9	APN	11	66,080,488 (GRCm38)	splice site	probably benign
IGL02325:Dnah9	APN	11	65,834,217 (GRCm38)	missense	probably damaging	1.00
IGL02426:Dnah9	APN	11	66,125,153 (GRCm38)	missense	probably benign
IGL02440:Dnah9	APN	11	65,955,246 (GRCm38)	missense	probably damaging	1.00
IGL02471:Dnah9	APN	11	65,947,618 (GRCm38)	nonsense	probably null
IGL02496:Dnah9	APN	11	66,029,363 (GRCm38)	missense	probably damaging	1.00
IGL02672:Dnah9	APN	11	65,927,601 (GRCm38)	missense	probably benign	0.02
IGL02718:Dnah9	APN	11	65,886,640 (GRCm38)	missense	probably damaging	0.99
IGL02832:Dnah9	APN	11	66,040,346 (GRCm38)	missense	probably damaging	1.00
IGL02851:Dnah9	APN	11	66,037,744 (GRCm38)	splice site	probably benign
IGL02859:Dnah9	APN	11	65,881,619 (GRCm38)	splice site	probably benign
IGL02864:Dnah9	APN	11	66,061,003 (GRCm38)	missense	probably damaging	1.00
IGL02954:Dnah9	APN	11	66,118,967 (GRCm38)	missense	probably damaging	1.00
IGL02987:Dnah9	APN	11	65,841,273 (GRCm38)	missense	probably benign	0.23
IGL02987:Dnah9	APN	11	65,855,272 (GRCm38)	missense	probably damaging	0.98
IGL03160:Dnah9	APN	11	66,108,054 (GRCm38)	missense	probably damaging	0.98
IGL03171:Dnah9	APN	11	65,981,241 (GRCm38)	missense	probably benign	0.13
IGL03180:Dnah9	APN	11	65,886,639 (GRCm38)	missense	probably damaging	0.99
IGL03388:Dnah9	APN	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
anarchy	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
sacco	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
Tweed	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
vanzetti	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
IGL02837:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
PIT4280001:Dnah9	UTSW	11	66,005,013 (GRCm38)	missense	probably benign	0.44
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0070:Dnah9	UTSW	11	66,160,040 (GRCm38)	missense	probably benign	0.10
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0180:Dnah9	UTSW	11	66,147,290 (GRCm38)	missense	probably damaging	1.00
R0195:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R0230:Dnah9	UTSW	11	65,855,315 (GRCm38)	missense	probably damaging	1.00
R0243:Dnah9	UTSW	11	65,911,852 (GRCm38)	missense	possibly damaging	0.91
R0279:Dnah9	UTSW	11	65,911,789 (GRCm38)	critical splice donor site	probably null
R0288:Dnah9	UTSW	11	66,025,134 (GRCm38)	critical splice donor site	probably null
R0309:Dnah9	UTSW	11	66,026,972 (GRCm38)	splice site	probably benign
R0356:Dnah9	UTSW	11	66,130,562 (GRCm38)	critical splice donor site	probably null
R0403:Dnah9	UTSW	11	66,084,789 (GRCm38)	missense	possibly damaging	0.90
R0413:Dnah9	UTSW	11	66,108,135 (GRCm38)	missense	probably damaging	1.00
R0448:Dnah9	UTSW	11	65,918,713 (GRCm38)	splice site	probably benign
R0496:Dnah9	UTSW	11	66,075,135 (GRCm38)	missense	probably null	1.00
R0557:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	1.00
R0584:Dnah9	UTSW	11	65,990,489 (GRCm38)	missense	probably damaging	1.00
R0598:Dnah9	UTSW	11	66,118,877 (GRCm38)	missense	probably benign	0.02
R0599:Dnah9	UTSW	11	65,965,689 (GRCm38)	missense	probably damaging	1.00
R0606:Dnah9	UTSW	11	65,841,333 (GRCm38)	missense	probably damaging	1.00
R0666:Dnah9	UTSW	11	66,085,458 (GRCm38)	missense	probably benign	0.01
R0715:Dnah9	UTSW	11	66,081,248 (GRCm38)	splice site	probably benign
R0726:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R0737:Dnah9	UTSW	11	66,107,898 (GRCm38)	missense	probably damaging	1.00
R0763:Dnah9	UTSW	11	66,155,530 (GRCm38)	missense	probably benign	0.30
R0792:Dnah9	UTSW	11	65,896,001 (GRCm38)	missense	possibly damaging	0.84
R0829:Dnah9	UTSW	11	66,005,176 (GRCm38)	missense	probably benign	0.00
R0973:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R0974:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R1055:Dnah9	UTSW	11	66,160,011 (GRCm38)	missense	probably damaging	1.00
R1081:Dnah9	UTSW	11	66,084,877 (GRCm38)	missense	probably damaging	0.99
R1184:Dnah9	UTSW	11	66,084,612 (GRCm38)	critical splice donor site	probably null
R1225:Dnah9	UTSW	11	65,871,060 (GRCm38)	missense	possibly damaging	0.94
R1304:Dnah9	UTSW	11	65,927,588 (GRCm38)	missense	probably damaging	0.98
R1417:Dnah9	UTSW	11	65,955,747 (GRCm38)	missense	probably damaging	0.96
R1439:Dnah9	UTSW	11	65,874,132 (GRCm38)	missense	probably benign	0.22
R1447:Dnah9	UTSW	11	66,108,482 (GRCm38)	missense	possibly damaging	0.65
R1450:Dnah9	UTSW	11	65,927,786 (GRCm38)	missense	probably damaging	1.00
R1470:Dnah9	UTSW	11	65,927,822 (GRCm38)	missense	probably benign	0.11
R1486:Dnah9	UTSW	11	65,834,272 (GRCm38)	missense	probably damaging	1.00
R1519:Dnah9	UTSW	11	65,881,761 (GRCm38)	missense	probably damaging	0.96
R1570:Dnah9	UTSW	11	66,112,330 (GRCm38)	missense	probably benign
R1617:Dnah9	UTSW	11	65,895,921 (GRCm38)	missense	probably damaging	1.00
R1623:Dnah9	UTSW	11	66,037,637 (GRCm38)	missense	probably damaging	1.00
R1626:Dnah9	UTSW	11	66,085,267 (GRCm38)	missense	probably benign	0.05
R1671:Dnah9	UTSW	11	65,927,963 (GRCm38)	missense	probably damaging	0.99
R1694:Dnah9	UTSW	11	65,954,824 (GRCm38)	nonsense	probably null
R1701:Dnah9	UTSW	11	65,911,924 (GRCm38)	missense	probably damaging	1.00
R1702:Dnah9	UTSW	11	66,085,195 (GRCm38)	missense	possibly damaging	0.72
R1708:Dnah9	UTSW	11	65,915,154 (GRCm38)	missense	probably benign	0.11
R1718:Dnah9	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
R1729:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1760:Dnah9	UTSW	11	65,981,222 (GRCm38)	missense	probably benign	0.31
R1784:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1793:Dnah9	UTSW	11	66,119,594 (GRCm38)	critical splice donor site	probably null
R1801:Dnah9	UTSW	11	65,955,297 (GRCm38)	missense	probably damaging	0.99
R1827:Dnah9	UTSW	11	65,850,061 (GRCm38)	missense	probably damaging	0.97
R1836:Dnah9	UTSW	11	66,118,841 (GRCm38)	missense	probably benign	0.10
R1840:Dnah9	UTSW	11	65,834,198 (GRCm38)	nonsense	probably null
R1847:Dnah9	UTSW	11	65,834,386 (GRCm38)	missense	probably damaging	1.00
R1872:Dnah9	UTSW	11	66,037,490 (GRCm38)	missense	probably benign	0.16
R1929:Dnah9	UTSW	11	65,976,398 (GRCm38)	missense	probably benign	0.05
R1969:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R1971:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R2027:Dnah9	UTSW	11	65,955,338 (GRCm38)	missense	probably benign	0.11
R2049:Dnah9	UTSW	11	66,044,683 (GRCm38)	missense	probably damaging	1.00
R2064:Dnah9	UTSW	11	66,145,435 (GRCm38)	missense	probably benign	0.31
R2104:Dnah9	UTSW	11	66,061,124 (GRCm38)	missense	probably damaging	1.00
R2109:Dnah9	UTSW	11	66,037,585 (GRCm38)	missense	probably damaging	1.00
R2160:Dnah9	UTSW	11	66,117,483 (GRCm38)	missense	probably damaging	1.00
R2172:Dnah9	UTSW	11	66,072,779 (GRCm38)	missense	probably damaging	1.00
R2198:Dnah9	UTSW	11	65,859,499 (GRCm38)	missense	possibly damaging	0.50
R2271:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2272:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2396:Dnah9	UTSW	11	66,085,158 (GRCm38)	missense	probably benign	0.01
R2398:Dnah9	UTSW	11	65,915,203 (GRCm38)	missense	probably damaging	1.00
R2418:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2419:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2510:Dnah9	UTSW	11	66,005,169 (GRCm38)	missense	probably damaging	1.00
R2680:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	probably benign	0.00
R2875:Dnah9	UTSW	11	66,168,461 (GRCm38)	missense	possibly damaging	0.89
R2979:Dnah9	UTSW	11	66,117,588 (GRCm38)	missense	possibly damaging	0.89
R3236:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3237:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3433:Dnah9	UTSW	11	66,075,112 (GRCm38)	missense	possibly damaging	0.85
R3737:Dnah9	UTSW	11	66,156,908 (GRCm38)	nonsense	probably null
R3820:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3821:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3822:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3861:Dnah9	UTSW	11	66,052,994 (GRCm38)	splice site	probably benign
R3918:Dnah9	UTSW	11	65,870,974 (GRCm38)	missense	possibly damaging	0.54
R4011:Dnah9	UTSW	11	65,834,464 (GRCm38)	missense	probably damaging	0.98
R4044:Dnah9	UTSW	11	66,133,635 (GRCm38)	missense	probably benign	0.03
R4072:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4076:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4097:Dnah9	UTSW	11	65,990,459 (GRCm38)	missense	probably damaging	1.00
R4409:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4410:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4417:Dnah9	UTSW	11	65,981,214 (GRCm38)	missense	possibly damaging	0.75
R4420:Dnah9	UTSW	11	66,118,749 (GRCm38)	missense	probably benign	0.00
R4434:Dnah9	UTSW	11	66,108,075 (GRCm38)	missense	possibly damaging	0.67
R4451:Dnah9	UTSW	11	65,881,641 (GRCm38)	missense	probably benign	0.07
R4452:Dnah9	UTSW	11	66,027,082 (GRCm38)	missense	probably damaging	0.96
R4454:Dnah9	UTSW	11	66,147,389 (GRCm38)	missense	probably damaging	0.96
R4551:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4552:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4590:Dnah9	UTSW	11	66,040,392 (GRCm38)	missense	probably damaging	1.00
R4595:Dnah9	UTSW	11	66,168,152 (GRCm38)	missense	probably benign
R4655:Dnah9	UTSW	11	65,955,732 (GRCm38)	missense	probably benign	0.00
R4667:Dnah9	UTSW	11	66,155,531 (GRCm38)	missense	probably benign
R4718:Dnah9	UTSW	11	66,085,473 (GRCm38)	missense	probably benign
R4720:Dnah9	UTSW	11	66,076,358 (GRCm38)	missense	probably damaging	1.00
R4734:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4749:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4765:Dnah9	UTSW	11	65,927,726 (GRCm38)	missense	probably damaging	1.00
R4905:Dnah9	UTSW	11	65,874,124 (GRCm38)	nonsense	probably null
R4963:Dnah9	UTSW	11	66,084,611 (GRCm38)	splice site	probably null
R5074:Dnah9	UTSW	11	65,850,040 (GRCm38)	missense	probably damaging	1.00
R5230:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	0.99
R5262:Dnah9	UTSW	11	66,112,333 (GRCm38)	missense	probably benign	0.34
R5364:Dnah9	UTSW	11	65,881,696 (GRCm38)	missense	possibly damaging	0.93
R5370:Dnah9	UTSW	11	66,029,354 (GRCm38)	missense	probably damaging	1.00
R5386:Dnah9	UTSW	11	66,029,356 (GRCm38)	missense	probably damaging	1.00
R5389:Dnah9	UTSW	11	66,095,314 (GRCm38)	nonsense	probably null
R5541:Dnah9	UTSW	11	66,145,336 (GRCm38)	missense	probably damaging	1.00
R5560:Dnah9	UTSW	11	65,881,740 (GRCm38)	missense	probably benign	0.00
R5576:Dnah9	UTSW	11	65,834,096 (GRCm38)	splice site	probably null
R5648:Dnah9	UTSW	11	65,927,755 (GRCm38)	missense	probably benign	0.00
R5653:Dnah9	UTSW	11	65,849,980 (GRCm38)	missense	probably damaging	0.99
R5713:Dnah9	UTSW	11	66,025,223 (GRCm38)	missense	possibly damaging	0.92
R5763:Dnah9	UTSW	11	65,955,239 (GRCm38)	missense	probably damaging	1.00
R5825:Dnah9	UTSW	11	66,126,601 (GRCm38)	missense	probably benign	0.01
R5831:Dnah9	UTSW	11	66,108,121 (GRCm38)	missense	probably benign	0.00
R5847:Dnah9	UTSW	11	66,095,240 (GRCm38)	frame shift	probably null
R5870:Dnah9	UTSW	11	66,085,210 (GRCm38)	missense	probably benign	0.01
R5902:Dnah9	UTSW	11	66,025,187 (GRCm38)	missense	probably benign	0.08
R5918:Dnah9	UTSW	11	65,834,199 (GRCm38)	missense	probably damaging	1.00
R5979:Dnah9	UTSW	11	65,834,481 (GRCm38)	missense	probably damaging	1.00
R6065:Dnah9	UTSW	11	66,145,397 (GRCm38)	missense	possibly damaging	0.65
R6065:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.05
R6086:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
R6086:Dnah9	UTSW	11	65,989,915 (GRCm38)	missense	probably damaging	0.99
R6102:Dnah9	UTSW	11	65,990,516 (GRCm38)	missense	probably damaging	0.97
R6120:Dnah9	UTSW	11	66,147,399 (GRCm38)	missense	probably benign
R6154:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.00
R6262:Dnah9	UTSW	11	65,881,805 (GRCm38)	splice site	probably null
R6265:Dnah9	UTSW	11	66,168,094 (GRCm38)	missense	probably benign	0.04
R6290:Dnah9	UTSW	11	65,841,375 (GRCm38)	missense	probably damaging	1.00
R6345:Dnah9	UTSW	11	66,037,693 (GRCm38)	missense	probably damaging	0.97
R6357:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
R6534:Dnah9	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
R6574:Dnah9	UTSW	11	66,168,281 (GRCm38)	missense	probably benign	0.37
R6582:Dnah9	UTSW	11	66,061,097 (GRCm38)	missense	probably damaging	1.00
R6700:Dnah9	UTSW	11	65,955,366 (GRCm38)	missense	probably damaging	1.00
R6800:Dnah9	UTSW	11	66,072,739 (GRCm38)	critical splice donor site	probably null
R6812:Dnah9	UTSW	11	65,981,329 (GRCm38)	missense	probably damaging	0.99
R6931:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	possibly damaging	0.63
R6944:Dnah9	UTSW	11	66,085,149 (GRCm38)	missense	possibly damaging	0.91
R6958:Dnah9	UTSW	11	66,076,341 (GRCm38)	missense	probably damaging	1.00
R6977:Dnah9	UTSW	11	66,107,909 (GRCm38)	missense	probably benign	0.37
R7021:Dnah9	UTSW	11	65,981,231 (GRCm38)	missense	probably benign
R7161:Dnah9	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
R7175:Dnah9	UTSW	11	66,133,637 (GRCm38)	missense	probably benign	0.03
R7199:Dnah9	UTSW	11	66,118,944 (GRCm38)	missense	probably benign	0.04
R7231:Dnah9	UTSW	11	65,965,647 (GRCm38)	missense	probably damaging	1.00
R7284:Dnah9	UTSW	11	65,990,476 (GRCm38)	missense	probably damaging	0.99
R7314:Dnah9	UTSW	11	65,989,851 (GRCm38)	missense	probably benign	0.00
R7350:Dnah9	UTSW	11	66,080,578 (GRCm38)	missense	probably damaging	1.00
R7420:Dnah9	UTSW	11	66,117,407 (GRCm38)	critical splice donor site	probably null
R7427:Dnah9	UTSW	11	65,955,219 (GRCm38)	missense	probably benign
R7477:Dnah9	UTSW	11	65,992,731 (GRCm38)	missense	probably damaging	0.98
R7515:Dnah9	UTSW	11	65,841,414 (GRCm38)	missense	probably benign	0.01
R7521:Dnah9	UTSW	11	65,989,837 (GRCm38)	missense	probably damaging	0.98
R7573:Dnah9	UTSW	11	66,125,215 (GRCm38)	missense	probably benign	0.43
R7659:Dnah9	UTSW	11	65,989,780 (GRCm38)	missense	probably damaging	0.99
R7707:Dnah9	UTSW	11	66,118,958 (GRCm38)	missense	probably damaging	1.00
R7749:Dnah9	UTSW	11	65,911,830 (GRCm38)	missense	probably damaging	1.00
R7792:Dnah9	UTSW	11	65,850,013 (GRCm38)	missense	probably damaging	1.00
R7808:Dnah9	UTSW	11	66,005,805 (GRCm38)	nonsense	probably null
R7814:Dnah9	UTSW	11	66,005,660 (GRCm38)	missense	probably damaging	1.00
R7818:Dnah9	UTSW	11	66,025,211 (GRCm38)	missense	possibly damaging	0.64
R7890:Dnah9	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
R7976:Dnah9	UTSW	11	65,841,401 (GRCm38)	missense	possibly damaging	0.91
R8121:Dnah9	UTSW	11	66,017,375 (GRCm38)	missense	probably benign	0.02
R8232:Dnah9	UTSW	11	65,855,323 (GRCm38)	missense	possibly damaging	0.91
R8311:Dnah9	UTSW	11	65,989,818 (GRCm38)	missense	probably benign	0.00
R8326:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	probably benign	0.01
R8338:Dnah9	UTSW	11	65,841,241 (GRCm38)	critical splice donor site	probably null
R8356:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8456:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8468:Dnah9	UTSW	11	65,831,730 (GRCm38)	missense	probably benign	0.00
R8721:Dnah9	UTSW	11	66,095,298 (GRCm38)	missense	probably damaging	1.00
R8747:Dnah9	UTSW	11	65,927,990 (GRCm38)	missense	possibly damaging	0.69
R8798:Dnah9	UTSW	11	65,905,231 (GRCm38)	missense	probably damaging	0.99
R8806:Dnah9	UTSW	11	65,859,483 (GRCm38)	missense	probably damaging	1.00
R8826:Dnah9	UTSW	11	65,849,916 (GRCm38)	missense	probably benign	0.13
R8837:Dnah9	UTSW	11	65,855,234 (GRCm38)	missense	possibly damaging	0.72
R8886:Dnah9	UTSW	11	66,053,014 (GRCm38)	missense	probably damaging	1.00
R8887:Dnah9	UTSW	11	65,855,384 (GRCm38)	missense	probably benign	0.01
R8921:Dnah9	UTSW	11	65,911,921 (GRCm38)	missense	probably benign
R8933:Dnah9	UTSW	11	65,855,252 (GRCm38)	missense	possibly damaging	0.88
R8949:Dnah9	UTSW	11	66,168,400 (GRCm38)	missense	possibly damaging	0.91
R8967:Dnah9	UTSW	11	66,125,112 (GRCm38)	critical splice donor site	probably null
R8979:Dnah9	UTSW	11	66,005,152 (GRCm38)	missense	probably benign
R8991:Dnah9	UTSW	11	65,886,680 (GRCm38)	missense	probably damaging	0.96
R9016:Dnah9	UTSW	11	66,108,030 (GRCm38)	missense	probably damaging	0.99
R9025:Dnah9	UTSW	11	66,005,825 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah9	UTSW	11	65,954,854 (GRCm38)	missense
R9047:Dnah9	UTSW	11	66,072,099 (GRCm38)	missense	possibly damaging	0.89
R9076:Dnah9	UTSW	11	66,117,638 (GRCm38)	missense	probably benign	0.21
R9113:Dnah9	UTSW	11	65,989,887 (GRCm38)	missense	probably damaging	1.00
R9152:Dnah9	UTSW	11	66,130,631 (GRCm38)	missense	probably damaging	1.00
R9187:Dnah9	UTSW	11	66,005,146 (GRCm38)	missense	probably benign
R9198:Dnah9	UTSW	11	65,955,744 (GRCm38)	missense	probably benign	0.02
R9203:Dnah9	UTSW	11	65,855,287 (GRCm38)	missense	possibly damaging	0.58
R9234:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	possibly damaging	0.68
R9245:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R9265:Dnah9	UTSW	11	65,841,255 (GRCm38)	missense	probably benign	0.01
R9307:Dnah9	UTSW	11	66,085,474 (GRCm38)	missense	probably benign	0.14
R9336:Dnah9	UTSW	11	65,870,949 (GRCm38)	missense	probably damaging	1.00
R9386:Dnah9	UTSW	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
R9498:Dnah9	UTSW	11	65,848,373 (GRCm38)	missense	probably damaging	0.99
R9508:Dnah9	UTSW	11	65,834,263 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah9	UTSW	11	66,085,483 (GRCm38)	missense	possibly damaging	0.92
R9577:Dnah9	UTSW	11	65,976,521 (GRCm38)	missense	probably benign	0.00
R9583:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R9587:Dnah9	UTSW	11	66,108,391 (GRCm38)	missense	probably null	0.92
R9612:Dnah9	UTSW	11	65,927,649 (GRCm38)	missense	probably benign	0.00
R9748:Dnah9	UTSW	11	66,085,464 (GRCm38)	missense	possibly damaging	0.51
R9749:Dnah9	UTSW	11	66,095,376 (GRCm38)	missense	probably damaging	1.00
R9759:Dnah9	UTSW	11	66,075,118 (GRCm38)	missense	probably null	0.93
R9784:Dnah9	UTSW	11	66,085,134 (GRCm38)	missense	probably damaging	0.99
V3553:Dnah9	UTSW	11	65,970,076 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah9	UTSW	11	66,085,479 (GRCm38)	missense	probably benign	0.07
X0028:Dnah9	UTSW	11	65,990,452 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,970,084 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,927,853 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,895,972 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,072,835 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,037,474 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah9	UTSW	11	66,126,650 (GRCm38)	missense	probably damaging	1.00
Z1186:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1186:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TAGGCAGGAGGGTTCTAGGTTCAC -3'
(R):5'- AGCTGAAGTCATTTGGTTCCCCAC -3'

Sequencing Primer
(F):5'- TGATGGCTGCCAGCTTC -3'
(R):5'- ACCTCTGGCTGTCAGCAATG -3'

Posted On

2014-03-28