Mutagenetix > Incidental Mutation

Incidental Mutation 'R1466:Dnah10'

166036

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

Accession Numbers

Ncbi RefSeq: NM_019536.1; MGI:1860299

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1466 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

124725085-124834308 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 124763096 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 1265 (Y1265N)

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000058440
AA Change: Y1322N

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: Y1322N

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000141137
AA Change: Y1265N

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: Y1265N

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Coding Region Coverage

1x: 99.4%
3x: 97.9%
10x: 90.8%
20x: 71.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 108 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abhd15	C	T	11: 77,515,410	A71V	probably damaging	Het
Adamts12	T	C	15: 11,311,359	F1234S	probably benign	Het
Ahnak	A	G	19: 9,015,875	D4841G	probably damaging	Het
Akap13	T	C	7: 75,729,049	S2095P	possibly damaging	Het
Ampd2	T	C	3: 108,080,337		probably null	Het
Arhgef17	G	T	7: 100,929,659	P694Q	possibly damaging	Het
Arrdc1	T	C	2: 24,925,795	I398V	probably benign	Het
Ash1l	T	C	3: 89,052,065	Y2250H	probably damaging	Het
Aspg	A	G	12: 112,121,852	N385D	probably benign	Het
Atxn3	G	A	12: 101,926,499	R319C	possibly damaging	Het
BC005561	T	A	5: 104,518,257	I215N	probably damaging	Het
Brca2	G	A	5: 150,552,258	A2478T	probably damaging	Het
C1s1	C	T	6: 124,531,131	C633Y	probably damaging	Het
C8g	C	T	2: 25,500,216	A6T	probably benign	Het
Cbl	A	T	9: 44,154,244	V706E	probably benign	Het
Cfhr1	C	T	1: 139,557,574	E45K	probably benign	Het
Chd7	G	A	4: 8,840,561		probably null	Het
Chek1	G	T	9: 36,725,857	A2E	probably damaging	Het
Cntnap1	C	A	11: 101,180,360	F366L	probably damaging	Het
Corin	C	T	5: 72,302,790		probably null	Het
Crb2	T	C	2: 37,783,388	Y99H	probably damaging	Het
Ctdspl2	G	A	2: 122,003,929	R332K	probably benign	Het
Cym	G	A	3: 107,213,458	T277I	probably damaging	Het
Cyp2d11	C	T	15: 82,391,735	C215Y	probably benign	Het
Dido1	G	A	2: 180,662,328	P1261L	probably damaging	Het
Dtx3l	G	A	16: 35,932,728	L503F	probably damaging	Het
Efhb	A	G	17: 53,437,178	F462L	probably damaging	Het
Enpep	T	A	3: 129,319,448	T203S	probably damaging	Het
Fat3	A	C	9: 16,375,482	V915G	probably damaging	Het
Fbln7	A	G	2: 128,877,429	T49A	probably benign	Het
Fcho1	C	T	8: 71,712,560	A418T	probably benign	Het
Fgf14	T	A	14: 124,676,539	K60M	probably benign	Het
Galnt4	A	G	10: 99,108,709	R99G	probably benign	Het
Gimap4	C	A	6: 48,691,282	Q196K	probably benign	Het
Glcci1	C	T	6: 8,537,964	T6I	probably damaging	Het
Gm10110	A	T	14: 89,898,075		noncoding transcript	Het
Gm4884	A	G	7: 41,043,128	K174E	probably damaging	Het
Gm6583	C	T	5: 112,354,764	G358D	probably benign	Het
Grip2	A	T	6: 91,788,443	D19E	probably damaging	Het
Grk4	T	C	5: 34,694,750	S113P	probably benign	Het
Hectd3	G	A	4: 116,996,566	E220K	probably damaging	Het
Helz2	G	A	2: 181,236,297	P903S	probably damaging	Het
Hydin	T	A	8: 110,532,953	V2519E	possibly damaging	Het
Ints11	G	A	4: 155,888,110		probably null	Het
Kif1a	A	G	1: 93,054,929	W718R	possibly damaging	Het
Kif1b	A	T	4: 149,223,252	Y839N	probably damaging	Het
Kif20b	T	A	19: 34,950,599	V1047D	probably benign	Het
Klhl23	T	C	2: 69,833,888	I527T	probably damaging	Het
Klra10	T	A	6: 130,279,315	R125S	probably damaging	Het
Klra10	T	C	6: 130,279,431	N87D	probably damaging	Het
Lars	G	A	18: 42,210,050	R1101C	probably damaging	Het
Lcn4	G	A	2: 26,668,576	P166L	probably damaging	Het
Letmd1	T	A	15: 100,472,542		probably null	Het
Map4k2	G	T	19: 6,341,917	W87L	probably damaging	Het
Mccc1	A	G	3: 35,974,286	V457A	probably benign	Het
Mdn1	T	A	4: 32,730,788	S2886T	probably benign	Het
Mroh2b	G	T	15: 4,925,684	D720Y	probably damaging	Het
Mrpl24	T	A	3: 87,921,928	Y21*	probably null	Het
Mrps35	C	T	6: 147,055,984	T169M	probably damaging	Het
Mtcl1	T	A	17: 66,380,435	D492V	probably damaging	Het
Muc2	A	G	7: 141,748,974	Y457C	probably damaging	Het
Muc4	G	A	16: 32,753,595	G1157D	probably benign	Het
Myg1	T	A	15: 102,337,390	L275Q	probably damaging	Het
Naga	T	A	15: 82,334,788	M237L	probably null	Het
Oc90	T	A	15: 65,897,720	Y96F	probably damaging	Het
Olfr1029	T	A	2: 85,975,995	F251I	probably damaging	Het
Olfr103	A	T	17: 37,336,956	L92H	probably benign	Het
Olfr1253	C	T	2: 89,752,267	C187Y	probably damaging	Het
Olfr46	A	G	7: 140,610,969	I268V	probably benign	Het
Olfr522	A	G	7: 140,162,203	V249A	probably damaging	Het
Orc4	A	T	2: 48,909,494	C324S	possibly damaging	Het
Pcdh10	T	G	3: 45,379,974	L241R	probably damaging	Het
Pdzrn4	T	C	15: 92,770,537	S857P	probably benign	Het
Plec	C	T	15: 76,185,908	E1000K	possibly damaging	Het
Plvap	A	T	8: 71,508,481	V149D	probably benign	Het
Ppef1	C	A	X: 160,625,674		probably null	Het
Prkaa1	C	A	15: 5,178,798	P507T	probably benign	Het
Ptch1	A	G	13: 63,524,969	Y804H	probably benign	Het
R3hdm2	A	G	10: 127,476,690	I434V	probably benign	Het
Rfx5	T	A	3: 94,956,303	Y88N	probably damaging	Het
Rnase2b	A	T	14: 51,162,839	K126*	probably null	Het
Rpl3l	A	G	17: 24,730,871	I15V	probably benign	Het
Saal1	G	T	7: 46,702,545		probably null	Het
Sbpl	A	C	17: 23,953,254	D230E	unknown	Het
Scn10a	T	C	9: 119,666,490	Y322C	probably damaging	Het
Sec16a	A	T	2: 26,431,157	Y1308N	probably damaging	Het
Sis	A	T	3: 72,932,060	D824E	possibly damaging	Het
Slc25a36	A	G	9: 97,080,355	F194L	probably damaging	Het
Slc27a4	T	A	2: 29,811,190	V331E	probably damaging	Het
Slc7a11	G	T	3: 50,381,073		probably null	Het
Slco4c1	A	T	1: 96,841,172	S322T	probably damaging	Het
Smarcc2	A	T	10: 128,474,245	T376S	probably damaging	Het
Srebf1	C	T	11: 60,200,702	R999H	probably benign	Het
St3gal3	A	C	4: 118,107,662	M1R	probably null	Het
Syp	A	T	X: 7,648,705		probably benign	Het
Tas1r2	A	G	4: 139,669,411	D687G	probably damaging	Het
Tekt4	A	T	17: 25,472,074	Q118L	probably benign	Het
Tph2	T	C	10: 115,079,695	N480S	probably benign	Het
Tsc2	A	T	17: 24,608,973	M839K	probably damaging	Het
Ttc22	T	C	4: 106,622,780	F77S	probably damaging	Het
Uaca	C	T	9: 60,854,321	A205V	possibly damaging	Het
Uhmk1	A	T	1: 170,208,653		probably null	Het
Usp17lc	A	G	7: 103,418,941	H481R	possibly damaging	Het
Vwa3a	A	G	7: 120,768,165	Y181C	probably damaging	Het
Wfikkn2	G	A	11: 94,238,895	T140I	probably damaging	Het
Zfp704	G	T	3: 9,447,348	T288N	possibly damaging	Het
Zfp93	T	C	7: 24,276,096	V502A	probably damaging	Het
Zzef1	C	T	11: 72,924,679	P2942S	probably damaging	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124828603	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124746616	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124794341	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124775512	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124777212	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124779154	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124783946	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124821341	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124732489	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124803328	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124787465	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124768927	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124755786	missense	probably benign
IGL01767:Dnah10	APN	5	124743737	splice site	probably benign
IGL01769:Dnah10	APN	5	124764944	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124783921	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124789812	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124804746	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124819366	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124833423	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124773067	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124773819	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124789796	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124793852	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124821287	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124787331	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124799005	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124773745	nonsense	probably null
IGL02740:Dnah10	APN	5	124826863	splice site	probably benign
IGL02746:Dnah10	APN	5	124730086	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124798014	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124801822	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124763133	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124730162	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124764886	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124748457	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124817643	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124817697	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124754290	missense	probably benign	0.06
frosty	UTSW	5	124828137	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124829529	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124730100	missense	probably benign
P0019:Dnah10	UTSW	5	124763066	missense	probably benign
P0037:Dnah10	UTSW	5	124817992	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124775524	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124726902	missense	probably benign
R0032:Dnah10	UTSW	5	124800891	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124800891	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124830744	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124763076	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124783834	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124783834	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124834075	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124796369	splice site	probably benign
R0321:Dnah10	UTSW	5	124823352	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124755735	missense	probably benign
R0480:Dnah10	UTSW	5	124808851	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124812723	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124775250	splice site	probably null
R0599:Dnah10	UTSW	5	124800953	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124747718	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124747718	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124750812	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124829577	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124797938	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124760014	splice site	probably null
R1248:Dnah10	UTSW	5	124755823	splice site	probably benign
R1366:Dnah10	UTSW	5	124753326	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124774986	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124762221	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124798945	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124789796	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124743686	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124763096	missense	probably benign
R1479:Dnah10	UTSW	5	124777889	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124754239	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124760952	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124829614	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124765562	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124760091	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124773190	splice site	probably null
R1828:Dnah10	UTSW	5	124761279	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124804689	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124832526	splice site	probably null
R1893:Dnah10	UTSW	5	124754317	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124758430	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124800984	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124782268	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124775203	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124833988	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124829587	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124746704	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124796341	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124814674	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124774981	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124761237	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124731466	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124819221	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124742000	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124762865	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124775478	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124817670	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124819412	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124796258	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124747630	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124773031	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124777926	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124730137	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124732330	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124819925	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124762869	splice site	probably null
R4651:Dnah10	UTSW	5	124729143	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124729143	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124828472	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124828472	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124828472	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124775517	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124747745	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124819344	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124773132	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124817748	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124762196	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124832513	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124811482	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124779258	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124798960	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124787420	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124785156	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124828137	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124791787	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124773566	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124743629	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124830493	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124753168	missense	probably benign
R5587:Dnah10	UTSW	5	124793913	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124742026	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124821386	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124747746	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124823373	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124791791	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124811482	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124808729	missense	probably benign
R6021:Dnah10	UTSW	5	124736984	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124801860	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124819210	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124805897	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124753174	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124770599	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124785175	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124823318	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124743679	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124794219	splice site	probably null
R6275:Dnah10	UTSW	5	124785184	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124775080	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124829646	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124809269	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124762782	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124758355	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124830033	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124760159	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124805805	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124808812	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124777826	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124790000	splice site	probably null
R6932:Dnah10	UTSW	5	124821450	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124787426	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124816142	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124822945	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124822942	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124813828	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124791791	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124832598	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124821269	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124747739	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124799031	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124746544	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124817712	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124777234	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124782361	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124726885	missense	probably benign
R7999:Dnah10	UTSW	5	124725258	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124800885	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124746612	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124828511	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124754266	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124800882	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124755726	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124828460	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124750794	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124782346	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124832502	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124773542	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124736831	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124816100	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124726847	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124814621	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124775346	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124765550	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124818117	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124789764	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124800951	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124813942	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124736993	missense
R9001:Dnah10	UTSW	5	124775451	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124743719	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124828077	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124762173	missense
R9133:Dnah10	UTSW	5	124782359	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124830411	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124794373	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124741925	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124736836	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124768926	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124794443	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124746613	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124823444	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124830043	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124775185	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124818077	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124777907	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124763066	missense	probably benign
U24488:Dnah10	UTSW	5	124813980	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124765697	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124775355	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124741955	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124747619	missense	possibly damaging	0.64
Z1177:Dnah10	UTSW	5	124817988	critical splice acceptor site	probably null

Predicted Primers

PCR Primer
(F):5'- GGGGCATCAAGCGAACTTTCACAG -3'
(R):5'- GGCTACACTGGCAAAGGCTGATTTC -3'

Sequencing Primer
(F):5'- TCACCTCTGAGCGCAGATG -3'
(R):5'- GTAGACCAGGGTTCCAACCTTC -3'

Posted On

2014-03-28