Incidental Mutation 'R1533:Lgr6'
| ID |
166707 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lgr6
|
| Ensembl Gene |
ENSMUSG00000042793 |
| Gene Name |
leucine-rich repeat-containing G protein-coupled receptor 6 |
| Synonyms |
A530037C04Rik |
| MMRRC Submission |
039572-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1533 (G1)
|
| Quality Score |
196 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
134911039-135033014 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 135032670 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Phenylalanine
at position 70
(Y70F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000035444
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044828]
|
| AlphaFold |
Q3UVD5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000044828
AA Change: Y70F
PolyPhen 2
Score 0.659 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000035444
Gene: ENSMUSG00000042793
AA Change: Y70F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
LRRNT
|
34 |
70 |
5.19e-3 |
SMART |
|
LRR
|
64 |
88 |
1.03e1 |
SMART |
|
LRR_TYP
|
89 |
112 |
6.52e-5 |
SMART |
|
LRR_TYP
|
113 |
136 |
2.71e-2 |
SMART |
|
LRR_TYP
|
137 |
160 |
4.79e-3 |
SMART |
|
LRR_TYP
|
161 |
184 |
1.58e-3 |
SMART |
|
LRR_TYP
|
185 |
208 |
2.36e-2 |
SMART |
|
LRR_TYP
|
209 |
232 |
3.39e-3 |
SMART |
|
LRR
|
233 |
255 |
8.97e0 |
SMART |
|
LRR_TYP
|
256 |
279 |
1.36e-2 |
SMART |
|
Blast:LRR
|
281 |
303 |
6e-7 |
BLAST |
|
LRR
|
327 |
350 |
9.24e1 |
SMART |
|
LRR
|
351 |
373 |
1.41e0 |
SMART |
|
LRR
|
374 |
396 |
4.84e1 |
SMART |
|
LRR_TYP
|
397 |
420 |
4.54e-4 |
SMART |
|
LRR_TYP
|
421 |
444 |
7.15e-2 |
SMART |
|
transmembrane domain
|
568 |
590 |
N/A |
INTRINSIC |
|
transmembrane domain
|
599 |
621 |
N/A |
INTRINSIC |
|
transmembrane domain
|
643 |
665 |
N/A |
INTRINSIC |
|
transmembrane domain
|
686 |
708 |
N/A |
INTRINSIC |
|
transmembrane domain
|
728 |
750 |
N/A |
INTRINSIC |
|
transmembrane domain
|
776 |
798 |
N/A |
INTRINSIC |
|
transmembrane domain
|
808 |
830 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182012
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182120
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182275
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182570
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183317
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a reporter/null allele are viable and fertile with no apparent abnormal phenotype. Similarly, mice homozygous for a knock-in allele are healthy and fertile. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
G |
C |
3: 121,928,807 (GRCm39) |
G1340A |
probably benign |
Het |
| Ambra1 |
T |
A |
2: 91,717,210 (GRCm39) |
Y836N |
probably damaging |
Het |
| Arhgap26 |
A |
T |
18: 39,504,130 (GRCm39) |
H144L |
probably benign |
Het |
| B3gnt5 |
A |
G |
16: 19,588,364 (GRCm39) |
I194M |
probably damaging |
Het |
| Bltp1 |
G |
T |
3: 37,095,524 (GRCm39) |
G4509V |
probably damaging |
Het |
| Bod1l |
A |
T |
5: 41,979,498 (GRCm39) |
C605* |
probably null |
Het |
| C2cd3 |
G |
T |
7: 100,055,284 (GRCm39) |
K482N |
possibly damaging |
Het |
| Cd300lg |
T |
A |
11: 101,934,047 (GRCm39) |
L98Q |
probably damaging |
Het |
| Cerkl |
T |
A |
2: 79,171,701 (GRCm39) |
I386F |
possibly damaging |
Het |
| Cfh |
T |
A |
1: 140,028,716 (GRCm39) |
D466V |
possibly damaging |
Het |
| Crtc1 |
A |
T |
8: 70,850,949 (GRCm39) |
I221N |
probably damaging |
Het |
| Ctnnbl1 |
T |
C |
2: 157,678,563 (GRCm39) |
S389P |
probably benign |
Het |
| Ctsb |
A |
T |
14: 63,376,544 (GRCm39) |
D258V |
probably damaging |
Het |
| Cuzd1 |
G |
T |
7: 130,913,432 (GRCm39) |
T395N |
probably damaging |
Het |
| Dnah6 |
T |
C |
6: 73,128,536 (GRCm39) |
T1240A |
probably benign |
Het |
| Dok7 |
T |
A |
5: 35,221,671 (GRCm39) |
|
probably null |
Het |
| Dscaml1 |
T |
C |
9: 45,361,882 (GRCm39) |
V214A |
probably damaging |
Het |
| Enpp6 |
A |
T |
8: 47,518,469 (GRCm39) |
Y199F |
probably benign |
Het |
| Entpd5 |
C |
A |
12: 84,441,434 (GRCm39) |
K111N |
probably damaging |
Het |
| Fam98a |
A |
G |
17: 75,848,276 (GRCm39) |
L146S |
probably damaging |
Het |
| Fhod3 |
A |
T |
18: 25,248,921 (GRCm39) |
I1367F |
probably damaging |
Het |
| Fmnl2 |
A |
G |
2: 52,995,549 (GRCm39) |
E424G |
probably damaging |
Het |
| Fpr3 |
T |
A |
17: 18,190,922 (GRCm39) |
Y64* |
probably null |
Het |
| Fzd6 |
A |
T |
15: 38,895,019 (GRCm39) |
H395L |
probably damaging |
Het |
| Gcsh |
T |
A |
8: 117,715,921 (GRCm39) |
H54L |
probably damaging |
Het |
| Gsdma |
T |
A |
11: 98,567,210 (GRCm39) |
S437T |
unknown |
Het |
| Gzmc |
A |
G |
14: 56,471,376 (GRCm39) |
V55A |
probably damaging |
Het |
| Hecw2 |
T |
A |
1: 53,965,704 (GRCm39) |
|
probably null |
Het |
| Ifi207 |
A |
G |
1: 173,555,306 (GRCm39) |
V792A |
probably benign |
Het |
| Itpr3 |
C |
A |
17: 27,314,534 (GRCm39) |
N661K |
possibly damaging |
Het |
| Jmy |
A |
T |
13: 93,577,819 (GRCm39) |
I783N |
probably benign |
Het |
| Kcmf1 |
T |
C |
6: 72,820,003 (GRCm39) |
E281G |
possibly damaging |
Het |
| Klra3 |
G |
C |
6: 130,310,107 (GRCm39) |
R138G |
probably benign |
Het |
| Lnx1 |
T |
G |
5: 74,780,678 (GRCm39) |
D330A |
probably damaging |
Het |
| Lrp5 |
T |
C |
19: 3,664,234 (GRCm39) |
N106S |
probably benign |
Het |
| Mamdc4 |
C |
A |
2: 25,459,759 (GRCm39) |
R135L |
possibly damaging |
Het |
| Mcm3ap |
A |
G |
10: 76,340,121 (GRCm39) |
E1464G |
probably damaging |
Het |
| Megf8 |
T |
C |
7: 25,034,280 (GRCm39) |
V666A |
possibly damaging |
Het |
| Mettl3 |
T |
A |
14: 52,534,385 (GRCm39) |
E331D |
probably benign |
Het |
| Mphosph9 |
T |
C |
5: 124,405,204 (GRCm39) |
K789R |
probably damaging |
Het |
| Mtf2 |
T |
C |
5: 108,239,995 (GRCm39) |
L234P |
probably damaging |
Het |
| Ncdn |
C |
A |
4: 126,642,491 (GRCm39) |
E389* |
probably null |
Het |
| Ndor1 |
A |
G |
2: 25,139,279 (GRCm39) |
S231P |
probably damaging |
Het |
| Nelfa |
T |
G |
5: 34,056,215 (GRCm39) |
K483Q |
probably damaging |
Het |
| Odad1 |
T |
A |
7: 45,592,282 (GRCm39) |
M354K |
probably benign |
Het |
| Opn1sw |
C |
T |
6: 29,378,923 (GRCm39) |
R243Q |
probably benign |
Het |
| Or13a24 |
T |
A |
7: 140,155,034 (GRCm39) |
|
probably null |
Het |
| Or9e1 |
A |
G |
11: 58,732,792 (GRCm39) |
N284S |
probably damaging |
Het |
| Pik3cd |
T |
C |
4: 149,739,653 (GRCm39) |
E584G |
probably damaging |
Het |
| Plcb3 |
A |
T |
19: 6,935,041 (GRCm39) |
M870K |
possibly damaging |
Het |
| Poc5 |
A |
G |
13: 96,528,152 (GRCm39) |
D16G |
probably damaging |
Het |
| Prpf40a |
A |
G |
2: 53,035,852 (GRCm39) |
I633T |
probably damaging |
Het |
| Ptpn13 |
G |
T |
5: 103,704,044 (GRCm39) |
E1359* |
probably null |
Het |
| Ptprr |
C |
A |
10: 116,024,113 (GRCm39) |
Y4* |
probably null |
Het |
| Rbm45 |
T |
C |
2: 76,202,503 (GRCm39) |
|
probably null |
Het |
| Rfng |
C |
T |
11: 120,672,687 (GRCm39) |
W320* |
probably null |
Het |
| Rgs6 |
G |
T |
12: 83,138,547 (GRCm39) |
V294L |
probably benign |
Het |
| Rufy4 |
T |
C |
1: 74,169,002 (GRCm39) |
|
probably null |
Het |
| Ruvbl2 |
T |
A |
7: 45,073,566 (GRCm39) |
N313I |
probably damaging |
Het |
| Sema4g |
G |
A |
19: 44,981,256 (GRCm39) |
V70M |
probably damaging |
Het |
| Siglec1 |
T |
C |
2: 130,918,078 (GRCm39) |
T969A |
probably benign |
Het |
| Slc22a27 |
T |
A |
19: 7,844,348 (GRCm39) |
T431S |
possibly damaging |
Het |
| Slc25a16 |
G |
A |
10: 62,756,643 (GRCm39) |
R38H |
probably damaging |
Het |
| Slc38a6 |
T |
C |
12: 73,391,626 (GRCm39) |
V296A |
probably benign |
Het |
| Slc39a11 |
C |
T |
11: 113,196,748 (GRCm39) |
V212I |
probably damaging |
Het |
| Sltm |
A |
G |
9: 70,493,948 (GRCm39) |
K782E |
probably damaging |
Het |
| Styxl1 |
T |
A |
5: 135,799,175 (GRCm39) |
Y23F |
probably damaging |
Het |
| Svs4 |
T |
C |
2: 164,120,148 (GRCm39) |
I20V |
unknown |
Het |
| Syt14 |
G |
T |
1: 192,613,084 (GRCm39) |
T572K |
possibly damaging |
Het |
| Tbc1d5 |
A |
T |
17: 51,227,603 (GRCm39) |
I214N |
possibly damaging |
Het |
| Tm9sf3 |
A |
G |
19: 41,227,223 (GRCm39) |
S283P |
probably benign |
Het |
| Tmtc1 |
C |
T |
6: 148,147,208 (GRCm39) |
|
probably null |
Het |
| Ttll7 |
T |
A |
3: 146,602,422 (GRCm39) |
N73K |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,602,802 (GRCm39) |
K18473N |
probably damaging |
Het |
| Ubr2 |
A |
C |
17: 47,278,173 (GRCm39) |
Y721* |
probably null |
Het |
| Vmn1r14 |
T |
A |
6: 57,211,286 (GRCm39) |
I288N |
probably damaging |
Het |
| Vmn2r103 |
T |
C |
17: 19,993,662 (GRCm39) |
I13T |
probably benign |
Het |
| Vps13a |
A |
T |
19: 16,678,494 (GRCm39) |
Y1162* |
probably null |
Het |
| Vps51 |
C |
A |
19: 6,121,497 (GRCm39) |
R175L |
probably benign |
Het |
| Zfp523 |
C |
A |
17: 28,423,473 (GRCm39) |
S149R |
probably benign |
Het |
| Zik1 |
A |
G |
7: 10,224,053 (GRCm39) |
I348T |
possibly damaging |
Het |
| Znfx1 |
T |
A |
2: 166,898,708 (GRCm39) |
H72L |
probably benign |
Het |
|
| Other mutations in Lgr6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02481:Lgr6
|
APN |
1 |
134,929,429 (GRCm39) |
splice site |
probably benign |
|
|
IGL02483:Lgr6
|
APN |
1 |
134,929,429 (GRCm39) |
splice site |
probably benign |
|
|
IGL03270:Lgr6
|
APN |
1 |
134,925,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0002:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Lgr6
|
UTSW |
1 |
135,032,799 (GRCm39) |
missense |
unknown |
|
|
R0294:Lgr6
|
UTSW |
1 |
134,915,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0361:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0390:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0731:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0734:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0741:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0742:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0765:Lgr6
|
UTSW |
1 |
134,921,624 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0903:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0904:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0905:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0906:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0907:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0908:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0967:Lgr6
|
UTSW |
1 |
134,921,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1079:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1131:Lgr6
|
UTSW |
1 |
134,915,042 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1440:Lgr6
|
UTSW |
1 |
134,915,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1728:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1728:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1729:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1729:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1729:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1729:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1730:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1730:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1730:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1730:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1739:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1739:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1739:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1739:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1762:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1762:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1762:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1762:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1782:Lgr6
|
UTSW |
1 |
134,915,717 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1783:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1783:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1783:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1783:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1784:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1784:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1784:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1784:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1785:Lgr6
|
UTSW |
1 |
134,915,747 (GRCm39) |
missense |
probably benign |
|
|
R1785:Lgr6
|
UTSW |
1 |
134,914,826 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1785:Lgr6
|
UTSW |
1 |
134,931,214 (GRCm39) |
missense |
probably benign |
|
|
R1785:Lgr6
|
UTSW |
1 |
134,918,373 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2020:Lgr6
|
UTSW |
1 |
135,003,013 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Lgr6
|
UTSW |
1 |
134,928,210 (GRCm39) |
splice site |
probably null |
|
|
R4629:Lgr6
|
UTSW |
1 |
135,032,670 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4792:Lgr6
|
UTSW |
1 |
134,949,544 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5001:Lgr6
|
UTSW |
1 |
134,918,370 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5191:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5194:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5195:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5196:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5197:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5228:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5230:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5243:Lgr6
|
UTSW |
1 |
135,037,010 (GRCm39) |
unclassified |
probably benign |
|
|
R5299:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5300:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5417:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5601:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5603:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5636:Lgr6
|
UTSW |
1 |
134,914,816 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5699:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5748:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5825:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5971:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6078:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6079:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6138:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6259:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6260:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6740:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6871:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6984:Lgr6
|
UTSW |
1 |
134,915,740 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R6986:Lgr6
|
UTSW |
1 |
134,921,694 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7233:Lgr6
|
UTSW |
1 |
134,928,214 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7699:Lgr6
|
UTSW |
1 |
134,923,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7700:Lgr6
|
UTSW |
1 |
134,923,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7734:Lgr6
|
UTSW |
1 |
134,930,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7849:Lgr6
|
UTSW |
1 |
134,915,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7970:Lgr6
|
UTSW |
1 |
134,921,723 (GRCm39) |
missense |
probably benign |
|
|
R8068:Lgr6
|
UTSW |
1 |
134,991,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8252:Lgr6
|
UTSW |
1 |
134,931,215 (GRCm39) |
missense |
probably null |
0.78 |
|
R8516:Lgr6
|
UTSW |
1 |
135,003,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8771:Lgr6
|
UTSW |
1 |
134,933,429 (GRCm39) |
nonsense |
probably null |
|
|
R8858:Lgr6
|
UTSW |
1 |
134,923,849 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8885:Lgr6
|
UTSW |
1 |
134,915,342 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9014:Lgr6
|
UTSW |
1 |
134,931,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9277:Lgr6
|
UTSW |
1 |
134,915,217 (GRCm39) |
nonsense |
probably null |
|
|
R9660:Lgr6
|
UTSW |
1 |
134,915,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9728:Lgr6
|
UTSW |
1 |
134,915,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Lgr6
|
UTSW |
1 |
134,915,809 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
Z1191:Lgr6
|
UTSW |
1 |
134,921,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCACTTCACCAGGTCCCACATTAAG -3'
(R):5'- GCCCAGCCTGTGAAACTGAATAACG -3'
Sequencing Primer
(F):5'- CCACATTAAGCCCATAGGGGTG -3'
(R):5'- GTGAAACTGAATAACGAAGATCACTC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation