Mutagenetix > Incidental Mutation

Incidental Mutation 'R1533:4932438A13Rik'

166725

Institutional Source

Beutler Lab

Gene Symbol

4932438A13Rik

Ensembl Gene

ENSMUSG00000037270

Gene Name

RIKEN cDNA 4932438A13 gene

Synonyms

Tweek, FSA

MMRRC Submission

039572-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R1533 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

36863104-37053033 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 37041375 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Valine at position 4509 (G4509V)

Ref Sequence

ENSEMBL: ENSMUSP00000117808 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057272] [ENSMUST00000138950] [ENSMUST00000152564]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057272
AA Change: G4509V

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000060199
Gene: ENSMUSG00000037270
AA Change: G4509V

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000136746

Predicted Effect

probably damaging
Transcript: ENSMUST00000138950
AA Change: G1011V

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000118092
Gene: ENSMUSG00000037270
AA Change: G1011V

Domain	Start	End	E-Value	Type
low complexity region	254	279	N/A	INTRINSIC
low complexity region	353	374	N/A	INTRINSIC
low complexity region	526	540	N/A	INTRINSIC
low complexity region	543	551	N/A	INTRINSIC
low complexity region	619	651	N/A	INTRINSIC
low complexity region	674	687	N/A	INTRINSIC
low complexity region	861	882	N/A	INTRINSIC
FSA_C	888	1492	N/A	SMART
low complexity region	1495	1506	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000141740
AA Change: G1089V

SMART Domains

Protein: ENSMUSP00000117814
Gene: ENSMUSG00000037270
AA Change: G1089V

Domain	Start	End	E-Value	Type
low complexity region	28	40	N/A	INTRINSIC
low complexity region	298	323	N/A	INTRINSIC
low complexity region	397	418	N/A	INTRINSIC
low complexity region	500	510	N/A	INTRINSIC
low complexity region	522	529	N/A	INTRINSIC
low complexity region	605	619	N/A	INTRINSIC
low complexity region	622	630	N/A	INTRINSIC
low complexity region	698	730	N/A	INTRINSIC
low complexity region	753	766	N/A	INTRINSIC
low complexity region	940	961	N/A	INTRINSIC
FSA_C	967	1571	N/A	SMART
low complexity region	1574	1585	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000146948
AA Change: G1214V

SMART Domains

Protein: ENSMUSP00000121356
Gene: ENSMUSG00000037270
AA Change: G1214V

Domain	Start	End	E-Value	Type
low complexity region	121	133	N/A	INTRINSIC
low complexity region	167	177	N/A	INTRINSIC
low complexity region	458	483	N/A	INTRINSIC
low complexity region	557	578	N/A	INTRINSIC
low complexity region	730	744	N/A	INTRINSIC
low complexity region	747	755	N/A	INTRINSIC
low complexity region	823	855	N/A	INTRINSIC
low complexity region	878	891	N/A	INTRINSIC
low complexity region	1065	1086	N/A	INTRINSIC
FSA_C	1092	1696	N/A	SMART
low complexity region	1699	1710	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148698

Predicted Effect

probably damaging
Transcript: ENSMUST00000152564
AA Change: G4509V

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000117808
Gene: ENSMUSG00000037270
AA Change: G4509V

Domain	Start	End	E-Value	Type
transmembrane domain	25	47	N/A	INTRINSIC
low complexity region	701	716	N/A	INTRINSIC
low complexity region	767	779	N/A	INTRINSIC
low complexity region	1127	1138	N/A	INTRINSIC
low complexity region	1154	1166	N/A	INTRINSIC
low complexity region	1226	1240	N/A	INTRINSIC
low complexity region	1381	1402	N/A	INTRINSIC
low complexity region	1541	1547	N/A	INTRINSIC
low complexity region	1593	1607	N/A	INTRINSIC
low complexity region	1810	1821	N/A	INTRINSIC
low complexity region	1981	1995	N/A	INTRINSIC
low complexity region	2182	2191	N/A	INTRINSIC
low complexity region	2336	2349	N/A	INTRINSIC
low complexity region	2614	2657	N/A	INTRINSIC
low complexity region	3468	3480	N/A	INTRINSIC
low complexity region	3717	3742	N/A	INTRINSIC
low complexity region	3816	3837	N/A	INTRINSIC
low complexity region	3919	3929	N/A	INTRINSIC
low complexity region	3941	3948	N/A	INTRINSIC
low complexity region	4024	4038	N/A	INTRINSIC
low complexity region	4041	4049	N/A	INTRINSIC
low complexity region	4117	4149	N/A	INTRINSIC
low complexity region	4172	4185	N/A	INTRINSIC
low complexity region	4359	4380	N/A	INTRINSIC
FSA_C	4386	4990	N/A	SMART
low complexity region	4993	5004	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000196036

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200245

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.4%
20x: 92.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is located on the long arm of chromosome 4 in a region that is associated with susceptibility to celiac disease. The encoded protein is similar to a Chinese hamster protein that is associated with spermatocyte and adipocyte differentiation. The C-terminus of the protein is also similar to a Caenorhabditis elegans protein that plays a role in lipid storage. In mammals, this protein is thought to function in the regulation of epithelial growth and differentiation, and in tumor development. [provided by RefSeq, Oct 2009]

Allele List at MGI

Other mutations in this stock

Total: 82 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca4	G	C	3: 122,135,158	G1340A	probably benign	Het
Ambra1	T	A	2: 91,886,865	Y836N	probably damaging	Het
Arhgap26	A	T	18: 39,371,077	H144L	probably benign	Het
B3gnt5	A	G	16: 19,769,614	I194M	probably damaging	Het
Bod1l	A	T	5: 41,822,155	C605*	probably null	Het
C2cd3	G	T	7: 100,406,077	K482N	possibly damaging	Het
Ccdc114	T	A	7: 45,942,858	M354K	probably benign	Het
Cd300lg	T	A	11: 102,043,221	L98Q	probably damaging	Het
Cerkl	T	A	2: 79,341,357	I386F	possibly damaging	Het
Cfh	T	A	1: 140,100,978	D466V	possibly damaging	Het
Crtc1	A	T	8: 70,398,299	I221N	probably damaging	Het
Ctnnbl1	T	C	2: 157,836,643	S389P	probably benign	Het
Ctsb	A	T	14: 63,139,095	D258V	probably damaging	Het
Cuzd1	G	T	7: 131,311,703	T395N	probably damaging	Het
Dnah6	T	C	6: 73,151,553	T1240A	probably benign	Het
Dok7	T	A	5: 35,064,327		probably null	Het
Dscaml1	T	C	9: 45,450,584	V214A	probably damaging	Het
Enpp6	A	T	8: 47,065,434	Y199F	probably benign	Het
Entpd5	C	A	12: 84,394,660	K111N	probably damaging	Het
Fam98a	A	G	17: 75,541,281	L146S	probably damaging	Het
Fhod3	A	T	18: 25,115,864	I1367F	probably damaging	Het
Fmnl2	A	G	2: 53,105,537	E424G	probably damaging	Het
Fpr3	T	A	17: 17,970,660	Y64*	probably null	Het
Fzd6	A	T	15: 39,031,624	H395L	probably damaging	Het
Gcsh	T	A	8: 116,989,182	H54L	probably damaging	Het
Gsdma	T	A	11: 98,676,384	S437T	unknown	Het
Gzmc	A	G	14: 56,233,919	V55A	probably damaging	Het
Hecw2	T	A	1: 53,926,545		probably null	Het
Ifi207	A	G	1: 173,727,740	V792A	probably benign	Het
Itpr3	C	A	17: 27,095,560	N661K	possibly damaging	Het
Jmy	A	T	13: 93,441,311	I783N	probably benign	Het
Kcmf1	T	C	6: 72,843,020	E281G	possibly damaging	Het
Klra3	G	C	6: 130,333,144	R138G	probably benign	Het
Lgr6	T	A	1: 135,104,932	Y70F	possibly damaging	Het
Lnx1	T	G	5: 74,620,017	D330A	probably damaging	Het
Lrp5	T	C	19: 3,614,234	N106S	probably benign	Het
Mamdc4	C	A	2: 25,569,747	R135L	possibly damaging	Het
Mcm3ap	A	G	10: 76,504,287	E1464G	probably damaging	Het
Megf8	T	C	7: 25,334,855	V666A	possibly damaging	Het
Mettl3	T	A	14: 52,296,928	E331D	probably benign	Het
Mphosph9	T	C	5: 124,267,141	K789R	probably damaging	Het
Mtf2	T	C	5: 108,092,129	L234P	probably damaging	Het
Ncdn	C	A	4: 126,748,698	E389*	probably null	Het
Ndor1	A	G	2: 25,249,267	S231P	probably damaging	Het
Nelfa	T	G	5: 33,898,871	K483Q	probably damaging	Het
Olfr311	A	G	11: 58,841,966	N284S	probably damaging	Het
Olfr538	T	A	7: 140,575,121		probably null	Het
Opn1sw	C	T	6: 29,378,924	R243Q	probably benign	Het
Pik3cd	T	C	4: 149,655,196	E584G	probably damaging	Het
Plcb3	A	T	19: 6,957,673	M870K	possibly damaging	Het
Poc5	A	G	13: 96,391,644	D16G	probably damaging	Het
Prpf40a	A	G	2: 53,145,840	I633T	probably damaging	Het
Ptpn13	G	T	5: 103,556,178	E1359*	probably null	Het
Ptprr	C	A	10: 116,188,208	Y4*	probably null	Het
Rbm45	T	C	2: 76,372,159		probably null	Het
Rfng	C	T	11: 120,781,861	W320*	probably null	Het
Rgs6	G	T	12: 83,091,773	V294L	probably benign	Het
Rufy4	T	C	1: 74,129,843		probably null	Het
Ruvbl2	T	A	7: 45,424,142	N313I	probably damaging	Het
Sema4g	G	A	19: 44,992,817	V70M	probably damaging	Het
Siglec1	T	C	2: 131,076,158	T969A	probably benign	Het
Slc22a27	T	A	19: 7,866,983	T431S	possibly damaging	Het
Slc25a16	G	A	10: 62,920,864	R38H	probably damaging	Het
Slc38a6	T	C	12: 73,344,852	V296A	probably benign	Het
Slc39a11	C	T	11: 113,305,922	V212I	probably damaging	Het
Sltm	A	G	9: 70,586,666	K782E	probably damaging	Het
Styxl1	T	A	5: 135,770,321	Y23F	probably damaging	Het
Svs4	T	C	2: 164,278,228	I20V	unknown	Het
Syt14	G	T	1: 192,930,776	T572K	possibly damaging	Het
Tbc1d5	A	T	17: 50,920,575	I214N	possibly damaging	Het
Tm9sf3	A	G	19: 41,238,784	S283P	probably benign	Het
Tmtc1	C	T	6: 148,245,710		probably null	Het
Ttll7	T	A	3: 146,896,667	N73K	probably damaging	Het
Ttn	T	A	2: 76,772,458	K18473N	probably damaging	Het
Ubr2	A	C	17: 46,967,247	Y721*	probably null	Het
Vmn1r14	T	A	6: 57,234,301	I288N	probably damaging	Het
Vmn2r103	T	C	17: 19,773,400	I13T	probably benign	Het
Vps13a	A	T	19: 16,701,130	Y1162*	probably null	Het
Vps51	C	A	19: 6,071,467	R175L	probably benign	Het
Zfp523	C	A	17: 28,204,499	S149R	probably benign	Het
Zik1	A	G	7: 10,490,126	I348T	possibly damaging	Het
Znfx1	T	A	2: 167,056,788	H72L	probably benign	Het

Other mutations in 4932438A13Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00428:4932438A13Rik	APN	3	37011727	missense	probably benign	0.00
IGL00434:4932438A13Rik	APN	3	36987299	missense	probably damaging	0.98
IGL00640:4932438A13Rik	APN	3	36908218	missense	probably damaging	1.00
IGL00693:4932438A13Rik	APN	3	37052547	utr 3 prime	probably benign
IGL00721:4932438A13Rik	APN	3	37030751	splice site	probably null
IGL00756:4932438A13Rik	APN	3	36908218	missense	probably damaging	1.00
IGL00896:4932438A13Rik	APN	3	37039462	missense	probably benign
IGL00902:4932438A13Rik	APN	3	37041345	missense	probably damaging	1.00
IGL00980:4932438A13Rik	APN	3	37000041	missense	probably damaging	1.00
IGL01019:4932438A13Rik	APN	3	37006984	critical splice acceptor site	probably null
IGL01025:4932438A13Rik	APN	3	37046280	missense	possibly damaging	0.89
IGL01306:4932438A13Rik	APN	3	37005013	splice site	probably benign
IGL01370:4932438A13Rik	APN	3	36947755	missense	probably benign	0.07
IGL01377:4932438A13Rik	APN	3	36973452	critical splice donor site	probably null
IGL01401:4932438A13Rik	APN	3	36942292	missense	probably benign
IGL01419:4932438A13Rik	APN	3	37048121	missense	probably damaging	1.00
IGL01432:4932438A13Rik	APN	3	37003759	missense	possibly damaging	0.87
IGL01433:4932438A13Rik	APN	3	36887770	missense	probably damaging	1.00
IGL01452:4932438A13Rik	APN	3	36996308	unclassified	probably benign
IGL01520:4932438A13Rik	APN	3	36973260	nonsense	probably null
IGL01524:4932438A13Rik	APN	3	36942382	missense	possibly damaging	0.90
IGL01628:4932438A13Rik	APN	3	37008485	missense	probably damaging	1.00
IGL01638:4932438A13Rik	APN	3	36974311	missense	probably damaging	1.00
IGL01650:4932438A13Rik	APN	3	36992673	splice site	probably benign
IGL01717:4932438A13Rik	APN	3	37034736	missense	probably benign
IGL01767:4932438A13Rik	APN	3	37041363	missense	probably benign	0.29
IGL01813:4932438A13Rik	APN	3	36928520	missense	possibly damaging	0.90
IGL01998:4932438A13Rik	APN	3	36957016	missense	possibly damaging	0.49
IGL02172:4932438A13Rik	APN	3	37004873	missense	probably damaging	0.99
IGL02197:4932438A13Rik	APN	3	36906735	missense	probably damaging	1.00
IGL02248:4932438A13Rik	APN	3	36969290	critical splice donor site	probably null
IGL02273:4932438A13Rik	APN	3	36921437	splice site	probably benign
IGL02403:4932438A13Rik	APN	3	37030664	missense	probably benign
IGL02492:4932438A13Rik	APN	3	37048113	missense	probably benign	0.04
IGL02517:4932438A13Rik	APN	3	36958868	missense	probably damaging	1.00
IGL02519:4932438A13Rik	APN	3	36895315	missense	probably damaging	1.00
IGL02586:4932438A13Rik	APN	3	37044608	nonsense	probably null
IGL02620:4932438A13Rik	APN	3	37035945	missense	possibly damaging	0.95
IGL02621:4932438A13Rik	APN	3	37041484	splice site	probably benign
IGL02670:4932438A13Rik	APN	3	36967305	nonsense	probably null
IGL02806:4932438A13Rik	APN	3	36946494	missense	possibly damaging	0.95
IGL02985:4932438A13Rik	APN	3	36958757	missense	probably damaging	0.99
IGL03004:4932438A13Rik	APN	3	36965677	splice site	probably benign
IGL03037:4932438A13Rik	APN	3	36969207	missense	probably benign	0.23
IGL03037:4932438A13Rik	APN	3	36969208	missense	probably damaging	1.00
IGL03062:4932438A13Rik	APN	3	37038517	splice site	probably benign
IGL03137:4932438A13Rik	APN	3	37034602	missense	probably damaging	0.98
IGL03150:4932438A13Rik	APN	3	36948066	missense	probably damaging	1.00
IGL03204:4932438A13Rik	APN	3	37050934	splice site	probably benign
IGL03207:4932438A13Rik	APN	3	36949996	missense	possibly damaging	0.73
IGL03256:4932438A13Rik	APN	3	36906683	splice site	probably benign
IGL03264:4932438A13Rik	APN	3	37002635	missense	probably damaging	1.00
IGL03265:4932438A13Rik	APN	3	37047991	missense	probably benign	0.00
IGL03303:4932438A13Rik	APN	3	36870077	missense	possibly damaging	0.90
admonished	UTSW	3	36948304	missense	probably damaging	1.00
alerted	UTSW	3	37033265	missense	possibly damaging	0.85
informed	UTSW	3	36965849	missense	probably damaging	1.00
resolved	UTSW	3	36921221	missense	possibly damaging	0.60
tipped	UTSW	3	36988085	missense	possibly damaging	0.81
warned	UTSW	3	36965621	missense	probably damaging	1.00
FR4340:4932438A13Rik	UTSW	3	37050752	critical splice acceptor site	probably benign
FR4737:4932438A13Rik	UTSW	3	37050754	critical splice acceptor site	probably benign
PIT4515001:4932438A13Rik	UTSW	3	36974236	missense	probably damaging	1.00
R0035:4932438A13Rik	UTSW	3	36987598	nonsense	probably null
R0047:4932438A13Rik	UTSW	3	36908192	missense	possibly damaging	0.83
R0047:4932438A13Rik	UTSW	3	36908192	missense	possibly damaging	0.83
R0068:4932438A13Rik	UTSW	3	36952221	missense	probably benign	0.28
R0068:4932438A13Rik	UTSW	3	36952221	missense	probably benign	0.28
R0092:4932438A13Rik	UTSW	3	37028159	missense	probably benign	0.41
R0233:4932438A13Rik	UTSW	3	36948563	nonsense	probably null
R0233:4932438A13Rik	UTSW	3	36948563	nonsense	probably null
R0256:4932438A13Rik	UTSW	3	36917773	missense	probably benign	0.01
R0277:4932438A13Rik	UTSW	3	36943182	nonsense	probably null
R0321:4932438A13Rik	UTSW	3	36906788	splice site	probably null
R0323:4932438A13Rik	UTSW	3	36943182	nonsense	probably null
R0335:4932438A13Rik	UTSW	3	36969152	missense	probably damaging	1.00
R0375:4932438A13Rik	UTSW	3	37046252	missense	probably damaging	0.99
R0437:4932438A13Rik	UTSW	3	36989804	missense	possibly damaging	0.81
R0445:4932438A13Rik	UTSW	3	37000065	missense	probably damaging	0.99
R0496:4932438A13Rik	UTSW	3	36987635	missense	probably damaging	1.00
R0531:4932438A13Rik	UTSW	3	37036825	missense	probably damaging	1.00
R0543:4932438A13Rik	UTSW	3	36996458	missense	probably benign	0.22
R0545:4932438A13Rik	UTSW	3	36987690	splice site	probably benign
R0674:4932438A13Rik	UTSW	3	37044626	missense	possibly damaging	0.86
R0745:4932438A13Rik	UTSW	3	36928463	missense	probably damaging	1.00
R0755:4932438A13Rik	UTSW	3	36946364	missense	probably damaging	1.00
R0785:4932438A13Rik	UTSW	3	36959334	splice site	probably benign
R1056:4932438A13Rik	UTSW	3	36983453	missense	possibly damaging	0.69
R1056:4932438A13Rik	UTSW	3	37044680	missense	probably benign	0.44
R1080:4932438A13Rik	UTSW	3	36988255	missense	probably damaging	1.00
R1103:4932438A13Rik	UTSW	3	36996523	missense	probably benign
R1119:4932438A13Rik	UTSW	3	36987045	missense	probably damaging	1.00
R1170:4932438A13Rik	UTSW	3	37044631	missense	probably damaging	0.98
R1183:4932438A13Rik	UTSW	3	36895303	missense	possibly damaging	0.51
R1186:4932438A13Rik	UTSW	3	36996312	unclassified	probably benign
R1201:4932438A13Rik	UTSW	3	36948375	missense	probably benign
R1219:4932438A13Rik	UTSW	3	36946470	nonsense	probably null
R1270:4932438A13Rik	UTSW	3	36952184	missense	probably damaging	1.00
R1273:4932438A13Rik	UTSW	3	36987210	missense	probably damaging	1.00
R1338:4932438A13Rik	UTSW	3	37052535	missense	unknown
R1364:4932438A13Rik	UTSW	3	36987030	missense	probably damaging	1.00
R1437:4932438A13Rik	UTSW	3	36942429	missense	possibly damaging	0.65
R1447:4932438A13Rik	UTSW	3	36965586	missense	probably damaging	0.98
R1467:4932438A13Rik	UTSW	3	37035945	missense	probably damaging	0.99
R1467:4932438A13Rik	UTSW	3	37035945	missense	probably damaging	0.99
R1470:4932438A13Rik	UTSW	3	36998331	missense	probably benign	0.31
R1470:4932438A13Rik	UTSW	3	36998331	missense	probably benign	0.31
R1481:4932438A13Rik	UTSW	3	37008434	missense	probably damaging	0.99
R1528:4932438A13Rik	UTSW	3	37052535	missense	unknown
R1546:4932438A13Rik	UTSW	3	36870056	missense	possibly damaging	0.64
R1606:4932438A13Rik	UTSW	3	36942399	missense	probably damaging	1.00
R1638:4932438A13Rik	UTSW	3	37035812	nonsense	probably null
R1772:4932438A13Rik	UTSW	3	36959432	missense	probably damaging	1.00
R1896:4932438A13Rik	UTSW	3	36908231	nonsense	probably null
R1919:4932438A13Rik	UTSW	3	37006983	critical splice acceptor site	probably null
R1983:4932438A13Rik	UTSW	3	36887865	missense	probably null	1.00
R1987:4932438A13Rik	UTSW	3	36953985	critical splice donor site	probably null
R1992:4932438A13Rik	UTSW	3	37000032	missense	probably benign	0.32
R1999:4932438A13Rik	UTSW	3	36908211	missense	probably damaging	1.00
R2004:4932438A13Rik	UTSW	3	36895378	missense	possibly damaging	0.77
R2010:4932438A13Rik	UTSW	3	36928551	missense	probably benign	0.09
R2027:4932438A13Rik	UTSW	3	37047961	splice site	probably benign
R2039:4932438A13Rik	UTSW	3	37003878	missense	possibly damaging	0.66
R2054:4932438A13Rik	UTSW	3	36947853	missense	probably benign	0.01
R2089:4932438A13Rik	UTSW	3	36988256	missense	probably damaging	1.00
R2091:4932438A13Rik	UTSW	3	36988256	missense	probably damaging	1.00
R2091:4932438A13Rik	UTSW	3	36953970	missense	probably damaging	1.00
R2091:4932438A13Rik	UTSW	3	36988256	missense	probably damaging	1.00
R2220:4932438A13Rik	UTSW	3	36875530	critical splice donor site	probably null
R2374:4932438A13Rik	UTSW	3	36885396	missense	probably benign	0.00
R2437:4932438A13Rik	UTSW	3	36958685	splice site	probably null
R2860:4932438A13Rik	UTSW	3	36965849	missense	probably damaging	1.00
R2861:4932438A13Rik	UTSW	3	36965849	missense	probably damaging	1.00
R2909:4932438A13Rik	UTSW	3	36947953	missense	probably damaging	1.00
R2925:4932438A13Rik	UTSW	3	37007122	missense	probably damaging	0.99
R2940:4932438A13Rik	UTSW	3	36958805	missense	probably damaging	1.00
R3015:4932438A13Rik	UTSW	3	36875462	missense	probably damaging	1.00
R3086:4932438A13Rik	UTSW	3	37011703	missense	possibly damaging	0.56
R3159:4932438A13Rik	UTSW	3	36959415	missense	probably benign	0.17
R3440:4932438A13Rik	UTSW	3	37041912	nonsense	probably null
R3703:4932438A13Rik	UTSW	3	36987581	missense	probably damaging	1.00
R3705:4932438A13Rik	UTSW	3	36987581	missense	probably damaging	1.00
R3795:4932438A13Rik	UTSW	3	37030565	missense	probably benign	0.30
R3820:4932438A13Rik	UTSW	3	37040434	missense	probably damaging	1.00
R3862:4932438A13Rik	UTSW	3	36885398	missense	possibly damaging	0.73
R3944:4932438A13Rik	UTSW	3	37030061	missense	possibly damaging	0.90
R4020:4932438A13Rik	UTSW	3	37012575	intron	probably benign
R4091:4932438A13Rik	UTSW	3	37030589	missense	probably benign	0.00
R4159:4932438A13Rik	UTSW	3	36931083	missense	probably benign	0.00
R4231:4932438A13Rik	UTSW	3	36920236	missense	probably benign	0.10
R4368:4932438A13Rik	UTSW	3	36988147	nonsense	probably null
R4413:4932438A13Rik	UTSW	3	36958681	splice site	probably null
R4475:4932438A13Rik	UTSW	3	37040395	missense	probably damaging	1.00
R4488:4932438A13Rik	UTSW	3	37003933	missense	probably null	0.93
R4489:4932438A13Rik	UTSW	3	37003933	missense	probably null	0.93
R4516:4932438A13Rik	UTSW	3	36895311	missense	possibly damaging	0.90
R4580:4932438A13Rik	UTSW	3	37030025	missense	probably benign	0.02
R4672:4932438A13Rik	UTSW	3	36889990	makesense	probably null
R4705:4932438A13Rik	UTSW	3	37041889	missense	probably benign	0.03
R4735:4932438A13Rik	UTSW	3	37004967	missense	possibly damaging	0.84
R4741:4932438A13Rik	UTSW	3	36942375	missense	probably damaging	0.99
R4754:4932438A13Rik	UTSW	3	37022466	nonsense	probably null
R4778:4932438A13Rik	UTSW	3	36937065	missense	possibly damaging	0.90
R4833:4932438A13Rik	UTSW	3	36964968	missense	probably damaging	0.96
R4896:4932438A13Rik	UTSW	3	36965937	missense	probably damaging	1.00
R4910:4932438A13Rik	UTSW	3	36998199	missense	probably damaging	1.00
R4922:4932438A13Rik	UTSW	3	36987165	missense	probably damaging	1.00
R4941:4932438A13Rik	UTSW	3	36917702	missense	probably damaging	1.00
R4941:4932438A13Rik	UTSW	3	36919901	missense	probably benign	0.41
R4980:4932438A13Rik	UTSW	3	36943312	missense	probably damaging	1.00
R5030:4932438A13Rik	UTSW	3	36943399	intron	probably benign
R5049:4932438A13Rik	UTSW	3	37040506	intron	probably benign
R5049:4932438A13Rik	UTSW	3	37041390	missense	probably damaging	1.00
R5089:4932438A13Rik	UTSW	3	36987502	missense	probably benign	0.02
R5092:4932438A13Rik	UTSW	3	37000085	missense	probably benign	0.14
R5122:4932438A13Rik	UTSW	3	37034757	splice site	probably null
R5210:4932438A13Rik	UTSW	3	37033265	missense	possibly damaging	0.85
R5246:4932438A13Rik	UTSW	3	37048050	missense	probably damaging	1.00
R5289:4932438A13Rik	UTSW	3	37000109	missense	probably damaging	0.97
R5348:4932438A13Rik	UTSW	3	37048146	missense	probably damaging	1.00
R5394:4932438A13Rik	UTSW	3	36917668	missense	probably damaging	1.00
R5434:4932438A13Rik	UTSW	3	36875516	missense	probably damaging	1.00
R5667:4932438A13Rik	UTSW	3	36917677	missense	probably benign	0.00
R5686:4932438A13Rik	UTSW	3	36917660	missense	probably benign	0.00
R5701:4932438A13Rik	UTSW	3	36921360	missense	probably benign	0.10
R5778:4932438A13Rik	UTSW	3	36958714	missense	probably damaging	1.00
R5787:4932438A13Rik	UTSW	3	36992733	splice site	probably null
R5800:4932438A13Rik	UTSW	3	37052443	missense	probably damaging	1.00
R5819:4932438A13Rik	UTSW	3	37048600	missense	probably benign	0.12
R5820:4932438A13Rik	UTSW	3	37039526	missense	probably benign	0.00
R5952:4932438A13Rik	UTSW	3	36965621	missense	probably damaging	1.00
R5975:4932438A13Rik	UTSW	3	36969221	missense	possibly damaging	0.64
R5996:4932438A13Rik	UTSW	3	36931116	missense	probably benign	0.07
R6192:4932438A13Rik	UTSW	3	36988169	missense	probably benign	0.00
R6225:4932438A13Rik	UTSW	3	36948304	missense	probably damaging	1.00
R6234:4932438A13Rik	UTSW	3	36983471	missense	probably benign	0.00
R6244:4932438A13Rik	UTSW	3	36956999	missense	probably benign
R6263:4932438A13Rik	UTSW	3	36931111	missense	probably benign	0.06
R6351:4932438A13Rik	UTSW	3	36908228	missense	probably damaging	1.00
R6380:4932438A13Rik	UTSW	3	37033307	missense	probably benign	0.19
R6468:4932438A13Rik	UTSW	3	37008443	missense	probably damaging	1.00
R6759:4932438A13Rik	UTSW	3	36988085	missense	possibly damaging	0.81
R6792:4932438A13Rik	UTSW	3	37011566	critical splice acceptor site	probably null
R6809:4932438A13Rik	UTSW	3	36874282	missense	probably damaging	0.98
R6841:4932438A13Rik	UTSW	3	37021481	missense	probably damaging	1.00
R6959:4932438A13Rik	UTSW	3	36967189	missense	probably damaging	1.00
R7102:4932438A13Rik	UTSW	3	36940798	missense	probably damaging	0.99
R7188:4932438A13Rik	UTSW	3	36950013	missense	probably benign	0.06
R7212:4932438A13Rik	UTSW	3	37048009	missense
R7425:4932438A13Rik	UTSW	3	36948341	missense	probably benign
R7425:4932438A13Rik	UTSW	3	36983394	missense	probably benign	0.02
R7451:4932438A13Rik	UTSW	3	37022807	splice site	probably null
R7604:4932438A13Rik	UTSW	3	36949843	splice site	probably null
R7622:4932438A13Rik	UTSW	3	36948413	nonsense	probably null
R7671:4932438A13Rik	UTSW	3	36943231	missense	probably damaging	0.99
R7699:4932438A13Rik	UTSW	3	36974172	missense	possibly damaging	0.67
R7699:4932438A13Rik	UTSW	3	37026154	missense	probably benign	0.00
R7700:4932438A13Rik	UTSW	3	36974172	missense	possibly damaging	0.67
R7700:4932438A13Rik	UTSW	3	37026154	missense	probably benign	0.00
R7748:4932438A13Rik	UTSW	3	36959335	critical splice acceptor site	probably null
R7767:4932438A13Rik	UTSW	3	36920287	critical splice donor site	probably null
R7787:4932438A13Rik	UTSW	3	36885408	missense	probably damaging	1.00
R7830:4932438A13Rik	UTSW	3	36964932	frame shift	probably null
R7849:4932438A13Rik	UTSW	3	37026328	missense
R7912:4932438A13Rik	UTSW	3	37007069	missense	probably damaging	0.99
R7914:4932438A13Rik	UTSW	3	36946283	missense	probably benign	0.13
R7945:4932438A13Rik	UTSW	3	36965893	missense	probably benign	0.03
R8039:4932438A13Rik	UTSW	3	36943214	missense	probably benign	0.12
R8101:4932438A13Rik	UTSW	3	37008502	missense	probably damaging	1.00
R8143:4932438A13Rik	UTSW	3	36946508	critical splice donor site	probably null
R8145:4932438A13Rik	UTSW	3	36998267	missense	probably damaging	1.00
R8171:4932438A13Rik	UTSW	3	36975713	missense	probably benign	0.00
R8210:4932438A13Rik	UTSW	3	37012881	missense
R8250:4932438A13Rik	UTSW	3	36917662	missense	probably damaging	0.99
R8369:4932438A13Rik	UTSW	3	37011603	missense
R8478:4932438A13Rik	UTSW	3	37033277	missense	possibly damaging	0.74
R8558:4932438A13Rik	UTSW	3	37048601	missense
R8688:4932438A13Rik	UTSW	3	37035917	missense
R8724:4932438A13Rik	UTSW	3	36890893	missense	probably damaging	0.99
R8818:4932438A13Rik	UTSW	3	36996548	missense	possibly damaging	0.60
R8869:4932438A13Rik	UTSW	3	36958858	missense	probably damaging	0.99
R8887:4932438A13Rik	UTSW	3	37033354	missense	possibly damaging	0.95
R8899:4932438A13Rik	UTSW	3	36988280	missense	probably damaging	1.00
R8907:4932438A13Rik	UTSW	3	36948146	nonsense	probably null
R8960:4932438A13Rik	UTSW	3	37012983	missense	probably damaging	1.00
R8990:4932438A13Rik	UTSW	3	36921221	missense	possibly damaging	0.60
R9021:4932438A13Rik	UTSW	3	36998344	missense	probably benign	0.00
R9048:4932438A13Rik	UTSW	3	37011777	missense
R9100:4932438A13Rik	UTSW	3	37044758	missense
R9166:4932438A13Rik	UTSW	3	36987367	missense	probably damaging	1.00
R9176:4932438A13Rik	UTSW	3	36956703	missense	possibly damaging	0.82
R9202:4932438A13Rik	UTSW	3	36890821	missense	probably benign
R9303:4932438A13Rik	UTSW	3	37044820	missense
R9305:4932438A13Rik	UTSW	3	37044820	missense
R9332:4932438A13Rik	UTSW	3	37050840	missense
R9362:4932438A13Rik	UTSW	3	36957013	missense	probably benign
R9493:4932438A13Rik	UTSW	3	37011736	missense
R9534:4932438A13Rik	UTSW	3	36998270	missense	probably benign	0.01
R9569:4932438A13Rik	UTSW	3	37012621	missense
R9593:4932438A13Rik	UTSW	3	36947941	missense	probably damaging	1.00
R9600:4932438A13Rik	UTSW	3	37041416	nonsense	probably null
R9733:4932438A13Rik	UTSW	3	37048583	missense
R9751:4932438A13Rik	UTSW	3	37011740	missense
RF013:4932438A13Rik	UTSW	3	37050757	critical splice acceptor site	probably benign
RF015:4932438A13Rik	UTSW	3	37050748	critical splice acceptor site	probably benign
RF021:4932438A13Rik	UTSW	3	37050748	critical splice acceptor site	probably benign
RF023:4932438A13Rik	UTSW	3	37050760	critical splice acceptor site	probably benign
RF034:4932438A13Rik	UTSW	3	37050760	critical splice acceptor site	probably benign
RF035:4932438A13Rik	UTSW	3	37050758	critical splice acceptor site	probably benign
RF055:4932438A13Rik	UTSW	3	37050757	critical splice acceptor site	probably benign
X0050:4932438A13Rik	UTSW	3	36957128	missense	probably damaging	1.00
Z1088:4932438A13Rik	UTSW	3	36987567	missense	probably damaging	1.00
Z1177:4932438A13Rik	UTSW	3	36919950	missense	probably benign
Z1177:4932438A13Rik	UTSW	3	36983440	missense	possibly damaging	0.88
Z1177:4932438A13Rik	UTSW	3	37036707	missense

Predicted Primers

PCR Primer
(F):5'- AAGCAACCGTGATCGAGAGATTAGC -3'
(R):5'- CTGAACTAATTCTCCTGCCCCTGAATG -3'

Sequencing Primer
(F):5'- CTGGGAAGGTCACAGTTAGATTC -3'
(R):5'- CTGCCCCTGAATGTTAAAAAAAAATG -3'

Posted On

2014-04-13