Mutagenetix > Incidental Mutation

Incidental Mutation 'R1535:Abcc9'

166888

Institutional Source

Beutler Lab

Gene Symbol

Abcc9

Ensembl Gene

ENSMUSG00000030249

Gene Name

ATP-binding cassette, sub-family C member 9

Synonyms

SUR2A, Sur2, SUR2B

MMRRC Submission

039574-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R1535 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

142533588-142648041 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 142610361 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Proline at position 601 (Q601P)

Ref Sequence

ENSEMBL: ENSMUSP00000144779 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000073173] [ENSMUST00000087527] [ENSMUST00000100827] [ENSMUST00000111771] [ENSMUST00000205202]

AlphaFold

P70170

Predicted Effect

probably damaging
Transcript: ENSMUST00000073173
AA Change: Q601P

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000072914
Gene: ENSMUSG00000030249
AA Change: Q601P

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	7.7e-33	PFAM
AAA	659	867	3.11e-13	SMART
coiled coil region	881	935	N/A	INTRINSIC
Pfam:ABC_membrane	956	1228	6.6e-35	PFAM
AAA	1300	1502	9.94e-12	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000087527
AA Change: Q601P

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000084805
Gene: ENSMUSG00000030249
AA Change: Q601P

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	8e-33	PFAM
AAA	694	902	3.11e-13	SMART
coiled coil region	916	970	N/A	INTRINSIC
Pfam:ABC_membrane	991	1263	6.8e-35	PFAM
AAA	1335	1537	9.94e-12	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000100827
AA Change: Q601P

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000098390
Gene: ENSMUSG00000030249
AA Change: Q601P

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	7.1e-35	PFAM
AAA	694	902	3.11e-13	SMART
coiled coil region	916	970	N/A	INTRINSIC
Pfam:ABC_membrane	991	1263	5.2e-38	PFAM
AAA	1335	1520	5.13e-14	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000111771
AA Change: Q601P

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000107401
Gene: ENSMUSG00000030249
AA Change: Q601P

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	1.4e-32	PFAM
AAA	694	889	3.77e-12	SMART
coiled coil region	903	957	N/A	INTRINSIC
Pfam:ABC_membrane	978	1250	1.2e-34	PFAM
AAA	1322	1524	9.94e-12	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000205202
AA Change: Q601P

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000144779
Gene: ENSMUSG00000030249
AA Change: Q601P

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	6.9e-35	PFAM
AAA	659	867	3.11e-13	SMART
coiled coil region	881	935	N/A	INTRINSIC
Pfam:ABC_membrane	956	1228	5e-38	PFAM
AAA	1300	1502	9.94e-12	SMART

Meta Mutation Damage Score

0.5896

Coding Region Coverage

1x: 99.2%
3x: 98.3%
10x: 96.4%
20x: 93.2%

Validation Efficiency

100% (75/75)

MGI Phenotype

FUNCTION: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The human protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015]
PHENOTYPE: Mice homozygous for a null allele display lower serum glucose, enhanced insulin action, growth retardation, hypertension and spontaneous death due to episodic coronary artery vasospasm. Homozygous exon 5 deletion leads to cardiac mitochondrial defects, cardiomyopathy, and early postnatal death. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Targeted(4)

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3110009E18Rik	T	C	1: 120,099,203 (GRCm39)	S99P	possibly damaging	Het
Abca16	T	A	7: 120,139,928 (GRCm39)	I1530N	probably benign	Het
Acap3	A	G	4: 155,980,631 (GRCm39)		probably benign	Het
Adamts16	A	T	13: 70,939,913 (GRCm39)		probably null	Het
Alpk2	G	C	18: 65,483,275 (GRCm39)	S244R	probably benign	Het
Aoc1l1	T	C	6: 48,952,398 (GRCm39)	F108L	probably damaging	Het
Atp8b1	C	T	18: 64,678,335 (GRCm39)	V854M	probably damaging	Het
Bend5	C	A	4: 111,316,960 (GRCm39)	D374E	probably benign	Het
Catsperg2	T	C	7: 29,397,671 (GRCm39)	D1014G	possibly damaging	Het
Ccer2	G	T	7: 28,456,822 (GRCm39)	G189*	probably null	Het
Ces2h	A	G	8: 105,741,118 (GRCm39)	T37A	probably benign	Het
Cfap68	C	T	9: 50,675,307 (GRCm39)	R40Q	probably damaging	Het
Cmah	T	C	13: 24,623,203 (GRCm39)	F213L	probably damaging	Het
Cntn2	T	C	1: 132,453,122 (GRCm39)	E390G	probably benign	Het
Coq7	C	T	7: 118,128,897 (GRCm39)	R46Q	possibly damaging	Het
Cpb1	T	A	3: 20,320,451 (GRCm39)	D136V	probably benign	Het
Cxcr2	T	C	1: 74,198,217 (GRCm39)	L237P	probably damaging	Het
Daam1	T	C	12: 71,998,692 (GRCm39)	L549P	unknown	Het
Diaph1	A	G	18: 38,029,146 (GRCm39)		probably null	Het
Dis3	G	T	14: 99,316,862 (GRCm39)	Q825K	probably damaging	Het
Dnah11	C	T	12: 117,982,465 (GRCm39)	R2568Q	probably damaging	Het
Dnah12	A	T	14: 26,538,279 (GRCm39)	R2312S	possibly damaging	Het
Dock9	C	T	14: 121,783,476 (GRCm39)	E2041K	probably damaging	Het
Eci1	A	G	17: 24,658,064 (GRCm39)	E282G	probably benign	Het
Egf	T	A	3: 129,484,427 (GRCm39)	T464S	probably benign	Het
Eif4g3	C	T	4: 137,824,613 (GRCm39)	P97S	probably damaging	Het
Emsy	A	G	7: 98,242,944 (GRCm39)	V1065A	possibly damaging	Het
Ep400	G	T	5: 110,856,032 (GRCm39)		probably benign	Het
Fam13a	A	C	6: 58,916,332 (GRCm39)	I607S	probably damaging	Het
Fam241b	A	G	10: 61,944,728 (GRCm39)	S113P	probably damaging	Het
Fbxl21	A	T	13: 56,671,340 (GRCm39)	M1L	probably benign	Het
Fnip2	C	A	3: 79,389,072 (GRCm39)	C553F	probably damaging	Het
Frmd3	G	T	4: 73,931,995 (GRCm39)		probably benign	Het
Grm4	G	A	17: 27,653,775 (GRCm39)	S470L	probably benign	Het
Gucy2e	T	A	11: 69,117,070 (GRCm39)	I784F	probably damaging	Het
H1f10	T	C	6: 87,958,130 (GRCm39)	Y70C	probably damaging	Het
Hmcn2	A	T	2: 31,310,419 (GRCm39)	T3338S	possibly damaging	Het
Idh1	C	T	1: 65,207,697 (GRCm39)	G161R	probably damaging	Het
Idi1	T	C	13: 8,936,945 (GRCm39)		probably benign	Het
Idi2l	A	T	13: 8,990,680 (GRCm39)		probably benign	Het
Kcnq2	C	T	2: 180,776,618 (GRCm39)	G90S	probably damaging	Het
Klhl29	A	G	12: 5,134,486 (GRCm39)	Y642H	probably damaging	Het
Lmtk3	T	A	7: 45,443,994 (GRCm39)		probably benign	Het
Macf1	A	T	4: 123,334,486 (GRCm39)	F4420I	probably benign	Het
Me1	A	G	9: 86,469,096 (GRCm39)	S470P	probably damaging	Het
Mfsd2b	A	G	12: 4,920,605 (GRCm39)	S71P	probably damaging	Het
Mfsd3	T	C	15: 76,586,979 (GRCm39)	L273P	probably damaging	Het
Mical1	A	G	10: 41,361,207 (GRCm39)	K757R	possibly damaging	Het
Myh9	A	T	15: 77,662,013 (GRCm39)	V782D	probably damaging	Het
Nab2	C	G	10: 127,500,916 (GRCm39)	E59Q	probably damaging	Het
Nfyc	A	T	4: 120,618,921 (GRCm39)	N244K	probably damaging	Het
Nupr2	A	G	5: 129,937,672 (GRCm39)	I80M	probably damaging	Het
Or4c15b	T	C	2: 89,113,401 (GRCm39)	I46M	probably benign	Het
Or51f1d	A	G	7: 102,700,576 (GRCm39)	T24A	probably benign	Het
Or5a1	A	G	19: 12,097,696 (GRCm39)	C115R	probably damaging	Het
Pkn3	A	G	2: 29,977,065 (GRCm39)	T602A	probably benign	Het
Prrc2b	T	A	2: 32,094,301 (GRCm39)	V561D	probably benign	Het
Psd2	T	A	18: 36,138,843 (GRCm39)	V489E	probably benign	Het
Rasal2	T	C	1: 157,057,629 (GRCm39)	T181A	probably benign	Het
Serpinb13	T	C	1: 106,909,886 (GRCm39)	M1T	probably null	Het
Sgsm1	A	T	5: 113,411,135 (GRCm39)	S864T	possibly damaging	Het
Slc5a10	C	A	11: 61,564,767 (GRCm39)	G404V	possibly damaging	Het
Slc6a1	G	T	6: 114,284,731 (GRCm39)	G263V	probably damaging	Het
Son	A	G	16: 91,456,622 (GRCm39)	K1790E	probably damaging	Het
Spata31e5	T	C	1: 28,816,505 (GRCm39)	E509G	probably damaging	Het
Syde2	A	G	3: 145,708,176 (GRCm39)		probably benign	Het
Tmem126a	T	C	7: 90,102,026 (GRCm39)	I58V	probably benign	Het
Vmn2r8	T	C	5: 108,950,040 (GRCm39)	Y269C	probably damaging	Het
Wdr87-ps	C	T	7: 29,229,004 (GRCm39)		noncoding transcript	Het
Yeats2	T	A	16: 20,008,115 (GRCm39)	S416T	probably damaging	Het
Zfp40	A	T	17: 23,394,843 (GRCm39)	H513Q	probably damaging	Het

Other mutations in Abcc9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Abcc9	APN	6	142,578,916 (GRCm39)	splice site	probably benign
IGL00670:Abcc9	APN	6	142,633,007 (GRCm39)	missense	probably damaging	1.00
IGL00675:Abcc9	APN	6	142,610,347 (GRCm39)	missense	probably damaging	1.00
IGL00741:Abcc9	APN	6	142,632,956 (GRCm39)	missense	probably benign
IGL01371:Abcc9	APN	6	142,602,340 (GRCm39)	missense	probably benign	0.04
IGL01686:Abcc9	APN	6	142,548,801 (GRCm39)	missense	possibly damaging	0.71
IGL01724:Abcc9	APN	6	142,610,259 (GRCm39)	missense	probably benign	0.00
IGL01807:Abcc9	APN	6	142,551,640 (GRCm39)	missense	probably damaging	1.00
IGL01941:Abcc9	APN	6	142,551,630 (GRCm39)	missense	probably damaging	1.00
IGL01946:Abcc9	APN	6	142,571,763 (GRCm39)	missense	probably benign	0.16
IGL02210:Abcc9	APN	6	142,633,097 (GRCm39)	missense	probably damaging	1.00
IGL02498:Abcc9	APN	6	142,617,265 (GRCm39)	critical splice donor site	probably null
IGL02535:Abcc9	APN	6	142,574,152 (GRCm39)	missense	probably benign	0.00
IGL02552:Abcc9	APN	6	142,551,645 (GRCm39)	missense	possibly damaging	0.94
IGL02812:Abcc9	APN	6	142,643,516 (GRCm39)	missense	possibly damaging	0.77
IGL02954:Abcc9	APN	6	142,592,007 (GRCm39)	missense	probably damaging	0.97
IGL03035:Abcc9	APN	6	142,573,319 (GRCm39)	missense	probably damaging	1.00
IGL03040:Abcc9	APN	6	142,598,323 (GRCm39)	nonsense	probably null
IGL03100:Abcc9	APN	6	142,640,270 (GRCm39)	missense	probably damaging	1.00
IGL03157:Abcc9	APN	6	142,551,649 (GRCm39)	splice site	probably benign
R0054:Abcc9	UTSW	6	142,547,500 (GRCm39)	critical splice donor site	probably null
R0054:Abcc9	UTSW	6	142,547,500 (GRCm39)	critical splice donor site	probably null
R0084:Abcc9	UTSW	6	142,604,277 (GRCm39)	missense	probably damaging	0.97
R0211:Abcc9	UTSW	6	142,634,710 (GRCm39)	missense	probably benign	0.01
R0349:Abcc9	UTSW	6	142,610,351 (GRCm39)	missense	probably benign	0.00
R0387:Abcc9	UTSW	6	142,585,230 (GRCm39)	nonsense	probably null
R0393:Abcc9	UTSW	6	142,591,604 (GRCm39)	splice site	probably benign
R0528:Abcc9	UTSW	6	142,638,606 (GRCm39)	missense	probably damaging	1.00
R0588:Abcc9	UTSW	6	142,548,787 (GRCm39)	nonsense	probably null
R0646:Abcc9	UTSW	6	142,627,830 (GRCm39)	missense	probably benign	0.05
R0691:Abcc9	UTSW	6	142,584,979 (GRCm39)	missense	possibly damaging	0.94
R0881:Abcc9	UTSW	6	142,592,029 (GRCm39)	missense	probably damaging	1.00
R1264:Abcc9	UTSW	6	142,592,103 (GRCm39)	splice site	probably benign
R1340:Abcc9	UTSW	6	142,628,581 (GRCm39)	splice site	probably benign
R1413:Abcc9	UTSW	6	142,573,245 (GRCm39)	missense	possibly damaging	0.65
R1413:Abcc9	UTSW	6	142,536,222 (GRCm39)	missense	probably damaging	1.00
R1595:Abcc9	UTSW	6	142,578,821 (GRCm39)	missense	probably benign	0.02
R1670:Abcc9	UTSW	6	142,540,448 (GRCm39)	missense	possibly damaging	0.89
R1769:Abcc9	UTSW	6	142,573,194 (GRCm39)	splice site	probably benign
R1888:Abcc9	UTSW	6	142,625,040 (GRCm39)	missense	probably benign
R1888:Abcc9	UTSW	6	142,625,040 (GRCm39)	missense	probably benign
R1918:Abcc9	UTSW	6	142,643,408 (GRCm39)	missense	probably damaging	1.00
R1925:Abcc9	UTSW	6	142,617,333 (GRCm39)	missense	probably damaging	0.98
R2019:Abcc9	UTSW	6	142,621,160 (GRCm39)	missense	probably damaging	1.00
R2698:Abcc9	UTSW	6	142,578,862 (GRCm39)	missense	possibly damaging	0.93
R2860:Abcc9	UTSW	6	142,571,736 (GRCm39)	missense	probably benign	0.01
R2861:Abcc9	UTSW	6	142,571,736 (GRCm39)	missense	probably benign	0.01
R2980:Abcc9	UTSW	6	142,633,034 (GRCm39)	missense	probably benign	0.00
R3115:Abcc9	UTSW	6	142,634,755 (GRCm39)	missense	probably benign	0.08
R3617:Abcc9	UTSW	6	142,625,015 (GRCm39)	missense	probably damaging	0.97
R3880:Abcc9	UTSW	6	142,584,959 (GRCm39)	missense	probably damaging	1.00
R4063:Abcc9	UTSW	6	142,551,645 (GRCm39)	missense	possibly damaging	0.94
R4065:Abcc9	UTSW	6	142,591,616 (GRCm39)	missense	probably damaging	1.00
R4290:Abcc9	UTSW	6	142,539,738 (GRCm39)	missense	probably benign	0.08
R4538:Abcc9	UTSW	6	142,560,138 (GRCm39)	critical splice donor site	probably null
R4615:Abcc9	UTSW	6	142,634,833 (GRCm39)	missense	possibly damaging	0.93
R4659:Abcc9	UTSW	6	142,618,321 (GRCm39)	splice site	probably null
R4774:Abcc9	UTSW	6	142,585,043 (GRCm39)	missense	probably damaging	1.00
R4788:Abcc9	UTSW	6	142,566,456 (GRCm39)	nonsense	probably null
R4832:Abcc9	UTSW	6	142,617,282 (GRCm39)	missense	probably damaging	1.00
R4844:Abcc9	UTSW	6	142,634,824 (GRCm39)	missense	probably benign	0.09
R4903:Abcc9	UTSW	6	142,546,691 (GRCm39)	missense	probably damaging	1.00
R4921:Abcc9	UTSW	6	142,536,162 (GRCm39)	missense	probably benign
R4960:Abcc9	UTSW	6	142,566,509 (GRCm39)	splice site	probably null
R4983:Abcc9	UTSW	6	142,627,867 (GRCm39)	missense	probably benign	0.44
R4986:Abcc9	UTSW	6	142,573,317 (GRCm39)	missense	probably benign	0.00
R5060:Abcc9	UTSW	6	142,571,836 (GRCm39)	intron	probably benign
R5120:Abcc9	UTSW	6	142,602,344 (GRCm39)	missense	probably benign	0.00
R5198:Abcc9	UTSW	6	142,571,726 (GRCm39)	missense	probably benign	0.00
R5301:Abcc9	UTSW	6	142,536,207 (GRCm39)	missense	probably benign	0.41
R5328:Abcc9	UTSW	6	142,627,785 (GRCm39)	missense	probably benign	0.25
R5568:Abcc9	UTSW	6	142,634,742 (GRCm39)	missense	possibly damaging	0.62
R5654:Abcc9	UTSW	6	142,571,371 (GRCm39)	intron	probably benign
R5694:Abcc9	UTSW	6	142,546,673 (GRCm39)	missense	probably damaging	1.00
R5734:Abcc9	UTSW	6	142,571,457 (GRCm39)	intron	probably benign
R5774:Abcc9	UTSW	6	142,574,285 (GRCm39)	missense	probably damaging	0.98
R5802:Abcc9	UTSW	6	142,602,402 (GRCm39)	critical splice acceptor site	probably null
R5890:Abcc9	UTSW	6	142,550,554 (GRCm39)	critical splice donor site	probably null
R5946:Abcc9	UTSW	6	142,571,678 (GRCm39)	missense	probably damaging	1.00
R5971:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
R6078:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
R6392:Abcc9	UTSW	6	142,627,825 (GRCm39)	missense	probably damaging	1.00
R6400:Abcc9	UTSW	6	142,638,435 (GRCm39)	makesense	probably null
R6478:Abcc9	UTSW	6	142,625,034 (GRCm39)	missense	probably damaging	1.00
R6481:Abcc9	UTSW	6	142,550,621 (GRCm39)	missense	probably damaging	0.99
R6564:Abcc9	UTSW	6	142,548,834 (GRCm39)	missense	probably damaging	1.00
R6700:Abcc9	UTSW	6	142,633,013 (GRCm39)	missense	possibly damaging	0.94
R6902:Abcc9	UTSW	6	142,624,953 (GRCm39)	missense	probably damaging	1.00
R6946:Abcc9	UTSW	6	142,624,953 (GRCm39)	missense	probably damaging	1.00
R6989:Abcc9	UTSW	6	142,634,707 (GRCm39)	missense	probably damaging	0.97
R7052:Abcc9	UTSW	6	142,604,261 (GRCm39)	missense	probably benign	0.00
R7062:Abcc9	UTSW	6	142,544,872 (GRCm39)	missense	probably damaging	1.00
R7121:Abcc9	UTSW	6	142,634,853 (GRCm39)	nonsense	probably null
R7284:Abcc9	UTSW	6	142,628,643 (GRCm39)	missense	probably damaging	1.00
R7296:Abcc9	UTSW	6	142,617,319 (GRCm39)	missense	probably damaging	1.00
R7353:Abcc9	UTSW	6	142,546,731 (GRCm39)	missense	probably damaging	1.00
R7359:Abcc9	UTSW	6	142,617,408 (GRCm39)	missense	probably damaging	1.00
R7815:Abcc9	UTSW	6	142,598,331 (GRCm39)	missense	probably damaging	1.00
R7894:Abcc9	UTSW	6	142,539,733 (GRCm39)	makesense	probably null
R8095:Abcc9	UTSW	6	142,590,048 (GRCm39)	missense	probably benign	0.22
R8099:Abcc9	UTSW	6	142,621,257 (GRCm39)	missense	probably damaging	1.00
R8245:Abcc9	UTSW	6	142,539,870 (GRCm39)	critical splice acceptor site	probably null
R8355:Abcc9	UTSW	6	142,638,478 (GRCm39)	missense	probably benign	0.00
R8356:Abcc9	UTSW	6	142,536,096 (GRCm39)	missense	probably benign	0.06
R8365:Abcc9	UTSW	6	142,544,798 (GRCm39)	missense	probably benign	0.03
R8846:Abcc9	UTSW	6	142,551,610 (GRCm39)	missense	possibly damaging	0.56
R8886:Abcc9	UTSW	6	142,546,420 (GRCm39)	intron	probably benign
R8939:Abcc9	UTSW	6	142,624,977 (GRCm39)	missense	probably damaging	0.99
R9049:Abcc9	UTSW	6	142,628,658 (GRCm39)	missense	probably damaging	0.99
R9113:Abcc9	UTSW	6	142,591,656 (GRCm39)	missense	probably damaging	1.00
R9368:Abcc9	UTSW	6	142,640,251 (GRCm39)	missense	probably damaging	1.00
R9401:Abcc9	UTSW	6	142,543,836 (GRCm39)	missense	possibly damaging	0.90
R9407:Abcc9	UTSW	6	142,574,229 (GRCm39)	missense	possibly damaging	0.88
R9597:Abcc9	UTSW	6	142,578,813 (GRCm39)	missense	possibly damaging	0.81
R9600:Abcc9	UTSW	6	142,536,102 (GRCm39)	missense	possibly damaging	0.54
R9687:Abcc9	UTSW	6	142,578,889 (GRCm39)	missense	probably benign	0.00
R9698:Abcc9	UTSW	6	142,571,757 (GRCm39)	missense	probably benign
R9761:Abcc9	UTSW	6	142,544,854 (GRCm39)	missense	possibly damaging	0.78
U15987:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
Z1177:Abcc9	UTSW	6	142,591,664 (GRCm39)	missense	probably null	0.96
Z1177:Abcc9	UTSW	6	142,571,708 (GRCm39)	missense	probably benign	0.07
Z1177:Abcc9	UTSW	6	142,540,484 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TTCAAGCCCCTGATGCAGGCAAAG -3'
(R):5'- TTTCCTAAGGCAGTTCTACCGCCG -3'

Sequencing Primer
(F):5'- CTCCCAGTTTATAGAGGCAGTGC -3'
(R):5'- CCGTGGCTTTCCAGGTATAG -3'

Posted On

2014-04-13