Incidental Mutation 'R1521:Urb1'
| ID |
167049 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
4921511H13Rik, 5730405K23Rik |
| MMRRC Submission |
040870-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1521 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
90751527-90810413 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 90753863 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Tryptophan
at position 2034
(R2034W)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038197]
[ENSMUST00000125429]
[ENSMUST00000138984]
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038197
|
| SMART Domains |
Protein: ENSMUSP00000043890
Gene: ENSMUSG00000039956
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:MRAP
|
1 |
90 |
1.7e-49 |
PFAM |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125429
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138984
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140920
AA Change: R2034W
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: R2034W
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adat1 |
A |
G |
8: 111,987,235 (GRCm38) |
L104P |
possibly damaging |
Het |
| Adgrf5 |
T |
C |
17: 43,430,552 (GRCm38) |
V360A |
probably benign |
Het |
| Ahnak |
G |
A |
19: 9,004,728 (GRCm38) |
M1125I |
probably benign |
Het |
| Akap12 |
T |
C |
10: 4,354,804 (GRCm38) |
V538A |
probably benign |
Het |
| Arhgef10l |
T |
C |
4: 140,515,438 (GRCm38) |
D1088G |
possibly damaging |
Het |
| Atp7b |
A |
T |
8: 22,027,673 (GRCm38) |
L268Q |
probably damaging |
Het |
| Atxn2 |
A |
C |
5: 121,779,591 (GRCm38) |
N516T |
probably damaging |
Het |
| Cacna1h |
T |
C |
17: 25,397,354 (GRCm38) |
M184V |
possibly damaging |
Het |
| Cacnb2 |
G |
T |
2: 14,614,352 (GRCm38) |
R66L |
probably benign |
Het |
| Casp8ap2 |
A |
G |
4: 32,631,867 (GRCm38) |
E96G |
probably damaging |
Het |
| Ccdc78 |
G |
T |
17: 25,788,781 (GRCm38) |
R264L |
probably damaging |
Het |
| Cdh4 |
G |
A |
2: 179,797,558 (GRCm38) |
R166H |
probably damaging |
Het |
| Cog7 |
C |
T |
7: 121,930,574 (GRCm38) |
D615N |
possibly damaging |
Het |
| Crtc2 |
T |
C |
3: 90,257,383 (GRCm38) |
V115A |
probably benign |
Het |
| Crybg1 |
A |
G |
10: 43,998,416 (GRCm38) |
S899P |
probably damaging |
Het |
| Ctdnep1 |
T |
A |
11: 69,988,635 (GRCm38) |
V128E |
probably damaging |
Het |
| Ctnna3 |
A |
G |
10: 64,959,842 (GRCm38) |
K780E |
probably benign |
Het |
| Cul7 |
T |
A |
17: 46,663,190 (GRCm38) |
L1467H |
probably damaging |
Het |
| Dazap2 |
T |
A |
15: 100,618,065 (GRCm38) |
Y91* |
probably null |
Het |
| Dcdc5 |
T |
C |
2: 106,351,669 (GRCm38) |
|
noncoding transcript |
Het |
| Dppa1 |
T |
A |
11: 46,610,473 (GRCm38) |
R74S |
possibly damaging |
Het |
| Elovl1 |
A |
T |
4: 118,432,000 (GRCm38) |
T241S |
probably benign |
Het |
| Eya1 |
G |
T |
1: 14,274,550 (GRCm38) |
Q86K |
probably damaging |
Het |
| Fam71a |
T |
A |
1: 191,164,022 (GRCm38) |
R141S |
probably benign |
Het |
| Fancm |
A |
T |
12: 65,121,704 (GRCm38) |
M1614L |
probably benign |
Het |
| Fcgbp |
C |
T |
7: 28,075,160 (GRCm38) |
T53I |
probably benign |
Het |
| Fpr3 |
T |
A |
17: 17,971,015 (GRCm38) |
W183R |
probably damaging |
Het |
| Galnt13 |
G |
A |
2: 54,854,645 (GRCm38) |
V119I |
probably benign |
Het |
| Gcfc2 |
T |
C |
6: 81,923,812 (GRCm38) |
S36P |
probably benign |
Het |
| Gdap2 |
T |
A |
3: 100,194,615 (GRCm38) |
D412E |
possibly damaging |
Het |
| Gm10184 |
T |
A |
17: 89,910,306 (GRCm38) |
N4I |
possibly damaging |
Het |
| Gm12258 |
T |
C |
11: 58,859,555 (GRCm38) |
C41R |
probably damaging |
Het |
| Grrp1 |
T |
C |
4: 134,251,350 (GRCm38) |
*272W |
probably null |
Het |
| Hipk1 |
T |
G |
3: 103,777,782 (GRCm38) |
E172D |
probably benign |
Het |
| Hmgcs1 |
T |
G |
13: 119,703,591 (GRCm38) |
L326R |
probably benign |
Het |
| Hs6st1 |
C |
A |
1: 36,068,886 (GRCm38) |
R77S |
probably damaging |
Het |
| Ifit3 |
A |
T |
19: 34,587,173 (GRCm38) |
N40Y |
probably damaging |
Het |
| Il1a |
T |
A |
2: 129,304,741 (GRCm38) |
Q144L |
possibly damaging |
Het |
| Itga7 |
A |
G |
10: 128,957,811 (GRCm38) |
E1128G |
possibly damaging |
Het |
| Itih2 |
T |
C |
2: 10,106,747 (GRCm38) |
D460G |
probably damaging |
Het |
| Ivns1abp |
G |
A |
1: 151,351,558 (GRCm38) |
C39Y |
probably damaging |
Het |
| Kif22 |
G |
T |
7: 127,027,839 (GRCm38) |
A646E |
probably damaging |
Het |
| Klhl29 |
T |
C |
12: 5,091,307 (GRCm38) |
Y559C |
probably damaging |
Het |
| Klhl7 |
T |
A |
5: 24,149,110 (GRCm38) |
|
probably null |
Het |
| Klhl9 |
A |
G |
4: 88,721,993 (GRCm38) |
S4P |
probably benign |
Het |
| Klk10 |
A |
G |
7: 43,782,880 (GRCm38) |
Q79R |
probably benign |
Het |
| Klk6 |
T |
C |
7: 43,829,275 (GRCm38) |
|
probably null |
Het |
| Lamc2 |
C |
T |
1: 153,166,263 (GRCm38) |
E42K |
probably benign |
Het |
| Lingo3 |
T |
C |
10: 80,835,721 (GRCm38) |
D125G |
probably benign |
Het |
| Map1b |
T |
C |
13: 99,432,739 (GRCm38) |
N1158S |
unknown |
Het |
| Masp1 |
T |
A |
16: 23,494,637 (GRCm38) |
N183Y |
probably damaging |
Het |
| Mdga2 |
A |
G |
12: 66,568,926 (GRCm38) |
Y636H |
probably benign |
Het |
| Micalcl |
T |
A |
7: 112,381,610 (GRCm38) |
S264T |
probably damaging |
Het |
| Mif |
A |
G |
10: 75,859,541 (GRCm38) |
V95A |
possibly damaging |
Het |
| Mmp17 |
G |
A |
5: 129,595,088 (GRCm38) |
|
probably null |
Het |
| Mmp23 |
T |
C |
4: 155,650,717 (GRCm38) |
R390G |
possibly damaging |
Het |
| Ncoa6 |
A |
C |
2: 155,415,222 (GRCm38) |
S800R |
possibly damaging |
Het |
| Nfix |
G |
A |
8: 84,726,526 (GRCm38) |
R300C |
probably damaging |
Het |
| Nr2e3 |
A |
T |
9: 59,949,205 (GRCm38) |
S67R |
probably damaging |
Het |
| Odf2l |
T |
C |
3: 145,149,036 (GRCm38) |
S545P |
possibly damaging |
Het |
| Olfr1256 |
G |
A |
2: 89,835,172 (GRCm38) |
R258* |
probably null |
Het |
| Olfr172 |
C |
T |
16: 58,760,853 (GRCm38) |
E108K |
probably damaging |
Het |
| Olfr591 |
T |
A |
7: 103,173,451 (GRCm38) |
Y62F |
probably benign |
Het |
| Olfr845 |
C |
T |
9: 19,338,652 (GRCm38) |
S64F |
probably benign |
Het |
| Olfr872 |
A |
C |
9: 20,260,432 (GRCm38) |
Q197H |
possibly damaging |
Het |
| Olfr916 |
T |
G |
9: 38,657,718 (GRCm38) |
I225L |
probably damaging |
Het |
| Olfr958 |
A |
T |
9: 39,550,784 (GRCm38) |
V29E |
possibly damaging |
Het |
| Otog |
A |
T |
7: 46,259,264 (GRCm38) |
H562L |
possibly damaging |
Het |
| Pcdh15 |
T |
C |
10: 74,594,191 (GRCm38) |
V1250A |
probably damaging |
Het |
| Pde1c |
A |
G |
6: 56,173,607 (GRCm38) |
V309A |
possibly damaging |
Het |
| Pfkfb4 |
A |
C |
9: 109,007,305 (GRCm38) |
T134P |
probably damaging |
Het |
| Phc3 |
G |
T |
3: 30,936,575 (GRCm38) |
Q498K |
possibly damaging |
Het |
| Phlpp1 |
T |
C |
1: 106,392,319 (GRCm38) |
V1348A |
probably damaging |
Het |
| Pik3ap1 |
T |
C |
19: 41,321,558 (GRCm38) |
D441G |
probably damaging |
Het |
| Pkd1l2 |
T |
C |
8: 117,065,500 (GRCm38) |
|
probably null |
Het |
| Pla2g4a |
T |
C |
1: 149,857,686 (GRCm38) |
|
probably null |
Het |
| Pola2 |
A |
T |
19: 5,948,406 (GRCm38) |
I376N |
probably damaging |
Het |
| Pold2 |
T |
A |
11: 5,876,833 (GRCm38) |
N34Y |
probably damaging |
Het |
| Ppp2r5c |
T |
C |
12: 110,554,886 (GRCm38) |
L281P |
probably damaging |
Het |
| Prss46 |
A |
G |
9: 110,849,635 (GRCm38) |
I29V |
probably benign |
Het |
| Ranbp6 |
A |
T |
19: 29,811,446 (GRCm38) |
V502E |
probably benign |
Het |
| Rdh14 |
T |
C |
12: 10,394,613 (GRCm38) |
F155L |
probably damaging |
Het |
| Rnaseh2a |
A |
T |
8: 84,965,858 (GRCm38) |
|
probably null |
Het |
| Rpp30 |
A |
G |
19: 36,094,385 (GRCm38) |
T118A |
possibly damaging |
Het |
| Rragd |
T |
C |
4: 32,996,005 (GRCm38) |
F117L |
probably damaging |
Het |
| S100a2 |
T |
A |
3: 90,591,292 (GRCm38) |
|
probably null |
Het |
| Sept12 |
T |
C |
16: 4,996,476 (GRCm38) |
K43R |
probably damaging |
Het |
| Sh3tc2 |
A |
G |
18: 62,008,488 (GRCm38) |
E1080G |
probably damaging |
Het |
| Slc26a9 |
A |
G |
1: 131,750,677 (GRCm38) |
K27R |
probably damaging |
Het |
| Spata17 |
T |
A |
1: 187,193,994 (GRCm38) |
K46N |
probably damaging |
Het |
| St14 |
A |
C |
9: 31,108,215 (GRCm38) |
D103E |
probably benign |
Het |
| St6galnac2 |
T |
A |
11: 116,684,347 (GRCm38) |
Q222L |
possibly damaging |
Het |
| Tdrd9 |
T |
C |
12: 112,036,410 (GRCm38) |
V831A |
probably damaging |
Het |
| Tert |
A |
G |
13: 73,642,056 (GRCm38) |
E843G |
probably damaging |
Het |
| Tex21 |
A |
G |
12: 76,204,270 (GRCm38) |
V464A |
probably benign |
Het |
| Tmem232 |
T |
A |
17: 65,484,501 (GRCm38) |
H124L |
probably damaging |
Het |
| Tmem5 |
A |
G |
10: 122,090,479 (GRCm38) |
W243R |
probably damaging |
Het |
| Tnfrsf19 |
T |
G |
14: 61,005,106 (GRCm38) |
S110R |
probably damaging |
Het |
| Tnnt3 |
A |
T |
7: 142,515,825 (GRCm38) |
K272* |
probably null |
Het |
| Tnxb |
T |
C |
17: 34,711,503 (GRCm38) |
L2054P |
probably damaging |
Het |
| Trcg1 |
A |
C |
9: 57,242,465 (GRCm38) |
D440A |
probably benign |
Het |
| Trpm3 |
A |
G |
19: 22,901,221 (GRCm38) |
E504G |
probably damaging |
Het |
| Trpm5 |
C |
T |
7: 143,082,889 (GRCm38) |
R437H |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,741,167 (GRCm38) |
R18134G |
probably damaging |
Het |
| Uchl5 |
A |
C |
1: 143,798,422 (GRCm38) |
M64L |
possibly damaging |
Het |
| Usp44 |
T |
A |
10: 93,847,186 (GRCm38) |
C452* |
probably null |
Het |
| Uvssa |
G |
A |
5: 33,413,934 (GRCm38) |
A641T |
probably damaging |
Het |
| Vmn1r204 |
T |
A |
13: 22,557,078 (GRCm38) |
I293N |
probably benign |
Het |
| Vmn2r84 |
A |
T |
10: 130,389,268 (GRCm38) |
C458S |
probably benign |
Het |
| Vmn2r85 |
T |
G |
10: 130,425,919 (GRCm38) |
H183P |
probably damaging |
Het |
| Vps13d |
G |
T |
4: 145,105,861 (GRCm38) |
T2825K |
probably benign |
Het |
| Zc3hc1 |
T |
A |
6: 30,376,025 (GRCm38) |
I179F |
probably benign |
Het |
| Zfp112 |
A |
G |
7: 24,125,785 (GRCm38) |
N393D |
probably damaging |
Het |
| Zfp558 |
A |
G |
9: 18,456,563 (GRCm38) |
S310P |
possibly damaging |
Het |
| Zfp560 |
A |
C |
9: 20,348,775 (GRCm38) |
|
probably null |
Het |
| Zfp668 |
C |
T |
7: 127,867,080 (GRCm38) |
E311K |
probably benign |
Het |
| Zfp763 |
T |
A |
17: 33,033,302 (GRCm38) |
M1L |
probably benign |
Het |
| Zfp947 |
A |
T |
17: 22,145,832 (GRCm38) |
M287K |
probably benign |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,753,321 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,779,098 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,792,814 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,804,458 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,757,761 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,777,560 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,760,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,769,586 (GRCm38) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,772,695 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,788,156 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,780,304 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,788,114 (GRCm38) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,769,469 (GRCm38) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,769,469 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,779,140 (GRCm38) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,779,140 (GRCm38) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,791,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,796,399 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,783,262 (GRCm38) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,777,422 (GRCm38) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,776,207 (GRCm38) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,779,138 (GRCm38) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,774,094 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,810,297 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,795,448 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,795,448 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,769,447 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,776,318 (GRCm38) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,769,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,769,466 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,796,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,752,014 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,752,014 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,774,745 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,777,440 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,760,452 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,774,048 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,772,626 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,788,082 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,787,397 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,767,040 (GRCm38) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,761,695 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,762,344 (GRCm38) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,774,256 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,774,256 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,774,798 (GRCm38) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,795,443 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,797,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,797,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,783,376 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,769,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,788,086 (GRCm38) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,774,537 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,769,394 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,788,146 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,787,444 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,776,271 (GRCm38) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,776,129 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,772,634 (GRCm38) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,804,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,753,518 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,769,555 (GRCm38) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,757,827 (GRCm38) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,759,842 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,795,414 (GRCm38) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,783,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,805,411 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,756,171 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,752,017 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,752,095 (GRCm38) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,783,274 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,792,748 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,792,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,776,163 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,804,537 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,772,764 (GRCm38) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,762,383 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,789,097 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,803,332 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,779,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,753,919 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,762,430 (GRCm38) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,787,414 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,810,268 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,779,083 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,782,106 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,791,166 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,752,115 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,774,768 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,787,408 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,761,634 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,792,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,797,910 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,772,573 (GRCm38) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,786,118 (GRCm38) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,779,152 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,791,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,774,625 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,803,423 (GRCm38) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,810,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,774,117 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,753,790 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,769,402 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,792,750 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,772,575 (GRCm38) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,786,208 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,774,862 (GRCm38) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,753,883 (GRCm38) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAAGGAGTCTTGTGACCTCTGCC -3'
(R):5'- CTCATGTCAGCCAGATGAGTATGCC -3'
Sequencing Primer
(F):5'- GCTCAGCCAATGACCGAAG -3'
(R):5'- TGAGTATGCCAGGCCCAAG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation