Incidental Mutation 'R1521:Urb1'
| ID |
167049 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
040870-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1521 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 90550751 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Tryptophan
at position 2034
(R2034W)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038197]
[ENSMUST00000125429]
[ENSMUST00000138984]
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038197
|
| SMART Domains |
Protein: ENSMUSP00000043890
Gene: ENSMUSG00000039956
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:MRAP
|
1 |
90 |
1.7e-49 |
PFAM |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125429
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138984
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140920
AA Change: R2034W
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: R2034W
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adat1 |
A |
G |
8: 112,713,867 (GRCm39) |
L104P |
possibly damaging |
Het |
| Adgrf5 |
T |
C |
17: 43,741,443 (GRCm39) |
V360A |
probably benign |
Het |
| Ahnak |
G |
A |
19: 8,982,092 (GRCm39) |
M1125I |
probably benign |
Het |
| Akap12 |
T |
C |
10: 4,304,804 (GRCm39) |
V538A |
probably benign |
Het |
| Arhgef10l |
T |
C |
4: 140,242,749 (GRCm39) |
D1088G |
possibly damaging |
Het |
| Atp7b |
A |
T |
8: 22,517,689 (GRCm39) |
L268Q |
probably damaging |
Het |
| Atxn2 |
A |
C |
5: 121,917,654 (GRCm39) |
N516T |
probably damaging |
Het |
| Cacna1h |
T |
C |
17: 25,616,328 (GRCm39) |
M184V |
possibly damaging |
Het |
| Cacnb2 |
G |
T |
2: 14,619,163 (GRCm39) |
R66L |
probably benign |
Het |
| Casp8ap2 |
A |
G |
4: 32,631,867 (GRCm39) |
E96G |
probably damaging |
Het |
| Ccdc78 |
G |
T |
17: 26,007,755 (GRCm39) |
R264L |
probably damaging |
Het |
| Cdh4 |
G |
A |
2: 179,439,351 (GRCm39) |
R166H |
probably damaging |
Het |
| Cog7 |
C |
T |
7: 121,529,797 (GRCm39) |
D615N |
possibly damaging |
Het |
| Crtc2 |
T |
C |
3: 90,164,690 (GRCm39) |
V115A |
probably benign |
Het |
| Crybg1 |
A |
G |
10: 43,874,412 (GRCm39) |
S899P |
probably damaging |
Het |
| Ctdnep1 |
T |
A |
11: 69,879,461 (GRCm39) |
V128E |
probably damaging |
Het |
| Ctnna3 |
A |
G |
10: 64,795,621 (GRCm39) |
K780E |
probably benign |
Het |
| Cul7 |
T |
A |
17: 46,974,116 (GRCm39) |
L1467H |
probably damaging |
Het |
| Dazap2 |
T |
A |
15: 100,515,946 (GRCm39) |
Y91* |
probably null |
Het |
| Dcdc5 |
T |
C |
2: 106,182,014 (GRCm39) |
|
noncoding transcript |
Het |
| Dppa1 |
T |
A |
11: 46,501,300 (GRCm39) |
R74S |
possibly damaging |
Het |
| Elovl1 |
A |
T |
4: 118,289,197 (GRCm39) |
T241S |
probably benign |
Het |
| Eya1 |
G |
T |
1: 14,344,774 (GRCm39) |
Q86K |
probably damaging |
Het |
| Fam110d |
T |
C |
4: 133,978,661 (GRCm39) |
*272W |
probably null |
Het |
| Fancm |
A |
T |
12: 65,168,478 (GRCm39) |
M1614L |
probably benign |
Het |
| Fcgbp |
C |
T |
7: 27,774,585 (GRCm39) |
T53I |
probably benign |
Het |
| Fpr3 |
T |
A |
17: 18,191,277 (GRCm39) |
W183R |
probably damaging |
Het |
| Galnt13 |
G |
A |
2: 54,744,657 (GRCm39) |
V119I |
probably benign |
Het |
| Garin4 |
T |
A |
1: 190,896,219 (GRCm39) |
R141S |
probably benign |
Het |
| Gcfc2 |
T |
C |
6: 81,900,793 (GRCm39) |
S36P |
probably benign |
Het |
| Gdap2 |
T |
A |
3: 100,101,931 (GRCm39) |
D412E |
possibly damaging |
Het |
| Gm12258 |
T |
C |
11: 58,750,381 (GRCm39) |
C41R |
probably damaging |
Het |
| Hipk1 |
T |
G |
3: 103,685,098 (GRCm39) |
E172D |
probably benign |
Het |
| Hmgcs1 |
T |
G |
13: 120,165,127 (GRCm39) |
L326R |
probably benign |
Het |
| Hs6st1 |
C |
A |
1: 36,107,967 (GRCm39) |
R77S |
probably damaging |
Het |
| Ifit3 |
A |
T |
19: 34,564,573 (GRCm39) |
N40Y |
probably damaging |
Het |
| Il1a |
T |
A |
2: 129,146,661 (GRCm39) |
Q144L |
possibly damaging |
Het |
| Itga7 |
A |
G |
10: 128,793,680 (GRCm39) |
E1128G |
possibly damaging |
Het |
| Itih2 |
T |
C |
2: 10,111,558 (GRCm39) |
D460G |
probably damaging |
Het |
| Ivns1abp |
G |
A |
1: 151,227,309 (GRCm39) |
C39Y |
probably damaging |
Het |
| Kif22 |
G |
T |
7: 126,627,011 (GRCm39) |
A646E |
probably damaging |
Het |
| Klhl29 |
T |
C |
12: 5,141,307 (GRCm39) |
Y559C |
probably damaging |
Het |
| Klhl7 |
T |
A |
5: 24,354,108 (GRCm39) |
|
probably null |
Het |
| Klhl9 |
A |
G |
4: 88,640,230 (GRCm39) |
S4P |
probably benign |
Het |
| Klk10 |
A |
G |
7: 43,432,304 (GRCm39) |
Q79R |
probably benign |
Het |
| Klk6 |
T |
C |
7: 43,478,699 (GRCm39) |
|
probably null |
Het |
| Kpna2rt |
T |
A |
17: 90,217,734 (GRCm39) |
N4I |
possibly damaging |
Het |
| Lamc2 |
C |
T |
1: 153,042,009 (GRCm39) |
E42K |
probably benign |
Het |
| Lingo3 |
T |
C |
10: 80,671,555 (GRCm39) |
D125G |
probably benign |
Het |
| Map1b |
T |
C |
13: 99,569,247 (GRCm39) |
N1158S |
unknown |
Het |
| Masp1 |
T |
A |
16: 23,313,387 (GRCm39) |
N183Y |
probably damaging |
Het |
| Mdga2 |
A |
G |
12: 66,615,700 (GRCm39) |
Y636H |
probably benign |
Het |
| Mical2 |
T |
A |
7: 111,980,817 (GRCm39) |
S264T |
probably damaging |
Het |
| Mif |
A |
G |
10: 75,695,375 (GRCm39) |
V95A |
possibly damaging |
Het |
| Mmp17 |
G |
A |
5: 129,672,152 (GRCm39) |
|
probably null |
Het |
| Mmp23 |
T |
C |
4: 155,735,174 (GRCm39) |
R390G |
possibly damaging |
Het |
| Ncoa6 |
A |
C |
2: 155,257,142 (GRCm39) |
S800R |
possibly damaging |
Het |
| Nfix |
G |
A |
8: 85,453,155 (GRCm39) |
R300C |
probably damaging |
Het |
| Nr2e3 |
A |
T |
9: 59,856,488 (GRCm39) |
S67R |
probably damaging |
Het |
| Odf2l |
T |
C |
3: 144,854,797 (GRCm39) |
S545P |
possibly damaging |
Het |
| Or10d3 |
A |
T |
9: 39,462,080 (GRCm39) |
V29E |
possibly damaging |
Het |
| Or4a47 |
G |
A |
2: 89,665,516 (GRCm39) |
R258* |
probably null |
Het |
| Or52s1b |
T |
A |
7: 102,822,658 (GRCm39) |
Y62F |
probably benign |
Het |
| Or5k1b |
C |
T |
16: 58,581,216 (GRCm39) |
E108K |
probably damaging |
Het |
| Or7e176 |
A |
C |
9: 20,171,728 (GRCm39) |
Q197H |
possibly damaging |
Het |
| Or7g27 |
C |
T |
9: 19,249,948 (GRCm39) |
S64F |
probably benign |
Het |
| Or8b51 |
T |
G |
9: 38,569,014 (GRCm39) |
I225L |
probably damaging |
Het |
| Otog |
A |
T |
7: 45,908,688 (GRCm39) |
H562L |
possibly damaging |
Het |
| Pcdh15 |
T |
C |
10: 74,430,023 (GRCm39) |
V1250A |
probably damaging |
Het |
| Pde1c |
A |
G |
6: 56,150,592 (GRCm39) |
V309A |
possibly damaging |
Het |
| Pfkfb4 |
A |
C |
9: 108,836,373 (GRCm39) |
T134P |
probably damaging |
Het |
| Phc3 |
G |
T |
3: 30,990,724 (GRCm39) |
Q498K |
possibly damaging |
Het |
| Phlpp1 |
T |
C |
1: 106,320,049 (GRCm39) |
V1348A |
probably damaging |
Het |
| Pik3ap1 |
T |
C |
19: 41,309,997 (GRCm39) |
D441G |
probably damaging |
Het |
| Pkd1l2 |
T |
C |
8: 117,792,239 (GRCm39) |
|
probably null |
Het |
| Pla2g4a |
T |
C |
1: 149,733,437 (GRCm39) |
|
probably null |
Het |
| Pola2 |
A |
T |
19: 5,998,434 (GRCm39) |
I376N |
probably damaging |
Het |
| Pold2 |
T |
A |
11: 5,826,833 (GRCm39) |
N34Y |
probably damaging |
Het |
| Ppp2r5c |
T |
C |
12: 110,521,320 (GRCm39) |
L281P |
probably damaging |
Het |
| Prss46 |
A |
G |
9: 110,678,703 (GRCm39) |
I29V |
probably benign |
Het |
| Ranbp6 |
A |
T |
19: 29,788,846 (GRCm39) |
V502E |
probably benign |
Het |
| Rdh14 |
T |
C |
12: 10,444,613 (GRCm39) |
F155L |
probably damaging |
Het |
| Rnaseh2a |
A |
T |
8: 85,692,487 (GRCm39) |
|
probably null |
Het |
| Rpp30 |
A |
G |
19: 36,071,785 (GRCm39) |
T118A |
possibly damaging |
Het |
| Rragd |
T |
C |
4: 32,996,005 (GRCm39) |
F117L |
probably damaging |
Het |
| Rxylt1 |
A |
G |
10: 121,926,384 (GRCm39) |
W243R |
probably damaging |
Het |
| S100a2 |
T |
A |
3: 90,498,599 (GRCm39) |
|
probably null |
Het |
| Septin12 |
T |
C |
16: 4,814,340 (GRCm39) |
K43R |
probably damaging |
Het |
| Sh3tc2 |
A |
G |
18: 62,141,559 (GRCm39) |
E1080G |
probably damaging |
Het |
| Slc26a9 |
A |
G |
1: 131,678,415 (GRCm39) |
K27R |
probably damaging |
Het |
| Spata17 |
T |
A |
1: 186,926,191 (GRCm39) |
K46N |
probably damaging |
Het |
| St14 |
A |
C |
9: 31,019,511 (GRCm39) |
D103E |
probably benign |
Het |
| St6galnac2 |
T |
A |
11: 116,575,173 (GRCm39) |
Q222L |
possibly damaging |
Het |
| Tdrd9 |
T |
C |
12: 112,002,844 (GRCm39) |
V831A |
probably damaging |
Het |
| Tert |
A |
G |
13: 73,790,175 (GRCm39) |
E843G |
probably damaging |
Het |
| Tex21 |
A |
G |
12: 76,251,044 (GRCm39) |
V464A |
probably benign |
Het |
| Tmem232 |
T |
A |
17: 65,791,496 (GRCm39) |
H124L |
probably damaging |
Het |
| Tnfrsf19 |
T |
G |
14: 61,242,555 (GRCm39) |
S110R |
probably damaging |
Het |
| Tnnt3 |
A |
T |
7: 142,069,562 (GRCm39) |
K272* |
probably null |
Het |
| Tnxb |
T |
C |
17: 34,930,477 (GRCm39) |
L2054P |
probably damaging |
Het |
| Trcg1 |
A |
C |
9: 57,149,748 (GRCm39) |
D440A |
probably benign |
Het |
| Trpm3 |
A |
G |
19: 22,878,585 (GRCm39) |
E504G |
probably damaging |
Het |
| Trpm5 |
C |
T |
7: 142,636,626 (GRCm39) |
R437H |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,571,511 (GRCm39) |
R18134G |
probably damaging |
Het |
| Uchl5 |
A |
C |
1: 143,674,160 (GRCm39) |
M64L |
possibly damaging |
Het |
| Usp44 |
T |
A |
10: 93,683,048 (GRCm39) |
C452* |
probably null |
Het |
| Uvssa |
G |
A |
5: 33,571,278 (GRCm39) |
A641T |
probably damaging |
Het |
| Vmn1r204 |
T |
A |
13: 22,741,248 (GRCm39) |
I293N |
probably benign |
Het |
| Vmn2r84 |
A |
T |
10: 130,225,137 (GRCm39) |
C458S |
probably benign |
Het |
| Vmn2r85 |
T |
G |
10: 130,261,788 (GRCm39) |
H183P |
probably damaging |
Het |
| Vps13d |
G |
T |
4: 144,832,431 (GRCm39) |
T2825K |
probably benign |
Het |
| Zc3hc1 |
T |
A |
6: 30,376,024 (GRCm39) |
I179F |
probably benign |
Het |
| Zfp112 |
A |
G |
7: 23,825,210 (GRCm39) |
N393D |
probably damaging |
Het |
| Zfp558 |
A |
G |
9: 18,367,859 (GRCm39) |
S310P |
possibly damaging |
Het |
| Zfp560 |
A |
C |
9: 20,260,071 (GRCm39) |
|
probably null |
Het |
| Zfp668 |
C |
T |
7: 127,466,252 (GRCm39) |
E311K |
probably benign |
Het |
| Zfp763 |
T |
A |
17: 33,252,276 (GRCm39) |
M1L |
probably benign |
Het |
| Zfp947 |
A |
T |
17: 22,364,813 (GRCm39) |
M287K |
probably benign |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,584,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,569,522 (GRCm39) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,554,715 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,580,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,549,003 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAAGGAGTCTTGTGACCTCTGCC -3'
(R):5'- CTCATGTCAGCCAGATGAGTATGCC -3'
Sequencing Primer
(F):5'- GCTCAGCCAATGACCGAAG -3'
(R):5'- TGAGTATGCCAGGCCCAAG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation