Incidental Mutation 'R1518:Dennd2b'
| ID |
167190 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd2b
|
| Ensembl Gene |
ENSMUSG00000031024 |
| Gene Name |
DENN domain containing 2B |
| Synonyms |
Denn2b, 2610305K15Rik, St5, 2010004M01Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.414)
|
| Stock # |
R1518 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
109123118-109302812 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 109156562 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 63
(S63P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000146747
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000077909]
[ENSMUST00000079282]
[ENSMUST00000084738]
[ENSMUST00000168005]
[ENSMUST00000207394]
[ENSMUST00000207745]
[ENSMUST00000208583]
|
| AlphaFold |
Q924W7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000077909
AA Change: S63P
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000077067
Gene: ENSMUSG00000031024
AA Change: S63P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
46 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
426 |
N/A |
INTRINSIC |
|
low complexity region
|
577 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
624 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
656 |
N/A |
INTRINSIC |
|
uDENN
|
690 |
781 |
1.16e-30 |
SMART |
|
DENN
|
788 |
972 |
7.84e-78 |
SMART |
|
low complexity region
|
1007 |
1014 |
N/A |
INTRINSIC |
|
dDENN
|
1019 |
1086 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000079282
AA Change: S63P
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000078264
Gene: ENSMUSG00000031024
AA Change: S63P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
28 |
46 |
N/A |
INTRINSIC |
|
low complexity region
|
197 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
407 |
426 |
N/A |
INTRINSIC |
|
low complexity region
|
577 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
624 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
656 |
N/A |
INTRINSIC |
|
uDENN
|
690 |
781 |
1.16e-30 |
SMART |
|
DENN
|
788 |
972 |
7.84e-78 |
SMART |
|
low complexity region
|
1007 |
1014 |
N/A |
INTRINSIC |
|
dDENN
|
1019 |
1086 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084738
|
| SMART Domains |
Protein: ENSMUSP00000081789
Gene: ENSMUSG00000031024
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
uDENN
|
273 |
364 |
1.16e-30 |
SMART |
|
DENN
|
371 |
555 |
7.84e-78 |
SMART |
|
low complexity region
|
590 |
597 |
N/A |
INTRINSIC |
|
dDENN
|
602 |
669 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168005
|
| SMART Domains |
Protein: ENSMUSP00000130119
Gene: ENSMUSG00000031024
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
228 |
239 |
N/A |
INTRINSIC |
|
uDENN
|
273 |
364 |
1.16e-30 |
SMART |
|
DENN
|
371 |
555 |
7.84e-78 |
SMART |
|
low complexity region
|
590 |
597 |
N/A |
INTRINSIC |
|
dDENN
|
602 |
669 |
3.12e-22 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000207394
AA Change: S63P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207745
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208557
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000208583
AA Change: S63P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000208981
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg4 |
T |
A |
9: 44,186,666 (GRCm39) |
M493L |
probably benign |
Het |
| Abtb2 |
G |
A |
2: 103,539,629 (GRCm39) |
V665I |
probably benign |
Het |
| Adamtsl1 |
C |
G |
4: 86,260,840 (GRCm39) |
S1017W |
probably damaging |
Het |
| Aebp1 |
A |
G |
11: 5,821,469 (GRCm39) |
T623A |
possibly damaging |
Het |
| Alox5 |
A |
G |
6: 116,390,741 (GRCm39) |
F470S |
probably damaging |
Het |
| Angpt2 |
T |
C |
8: 18,755,855 (GRCm39) |
E204G |
probably benign |
Het |
| Apip |
A |
G |
2: 102,919,838 (GRCm39) |
E138G |
probably damaging |
Het |
| Apob |
C |
T |
12: 8,039,207 (GRCm39) |
T466M |
probably benign |
Het |
| Atp2b3 |
GACAACA |
GACA |
X: 72,588,729 (GRCm39) |
|
probably benign |
Het |
| Atxn7l3 |
A |
T |
11: 102,185,340 (GRCm39) |
D56E |
probably benign |
Het |
| Cacna1s |
C |
T |
1: 136,026,289 (GRCm39) |
A1092V |
probably damaging |
Het |
| Calr3 |
A |
G |
8: 73,181,044 (GRCm39) |
F183L |
probably damaging |
Het |
| Cd300lb |
T |
A |
11: 114,816,877 (GRCm39) |
D55V |
probably benign |
Het |
| Chid1 |
A |
C |
7: 141,108,384 (GRCm39) |
V145G |
probably damaging |
Het |
| Chst15 |
T |
C |
7: 131,871,855 (GRCm39) |
N142S |
probably damaging |
Het |
| Cnot4 |
C |
T |
6: 35,028,389 (GRCm39) |
R409Q |
probably damaging |
Het |
| Cope |
T |
G |
8: 70,765,411 (GRCm39) |
I287S |
possibly damaging |
Het |
| Cpd |
A |
T |
11: 76,731,212 (GRCm39) |
|
probably null |
Het |
| Cux1 |
G |
T |
5: 136,337,133 (GRCm39) |
T785K |
probably benign |
Het |
| Dthd1 |
T |
C |
5: 62,979,383 (GRCm39) |
S348P |
probably damaging |
Het |
| Eno3 |
G |
T |
11: 70,551,903 (GRCm39) |
E64* |
probably null |
Het |
| Entpd1 |
T |
A |
19: 40,713,507 (GRCm39) |
Y184* |
probably null |
Het |
| Erv3 |
A |
T |
2: 131,698,083 (GRCm39) |
M92K |
probably benign |
Het |
| Flg2 |
T |
A |
3: 93,110,445 (GRCm39) |
H824Q |
unknown |
Het |
| Fndc9 |
G |
A |
11: 46,128,930 (GRCm39) |
G150S |
probably benign |
Het |
| Gdap1 |
G |
A |
1: 17,217,169 (GRCm39) |
V43I |
possibly damaging |
Het |
| Ifi213 |
C |
A |
1: 173,417,229 (GRCm39) |
L394F |
probably damaging |
Het |
| Ift88 |
A |
G |
14: 57,668,085 (GRCm39) |
T29A |
possibly damaging |
Het |
| Kdm4c |
A |
T |
4: 74,252,063 (GRCm39) |
I437L |
probably benign |
Het |
| Kras |
T |
A |
6: 145,177,977 (GRCm39) |
E98D |
probably benign |
Het |
| Lcorl |
C |
A |
5: 45,891,543 (GRCm39) |
R353I |
possibly damaging |
Het |
| Lrrc4c |
A |
G |
2: 97,460,921 (GRCm39) |
I516V |
probably benign |
Het |
| Lrrc51 |
T |
C |
7: 101,564,803 (GRCm39) |
D85G |
probably damaging |
Het |
| Lypd6b |
G |
A |
2: 49,837,504 (GRCm39) |
A159T |
probably damaging |
Het |
| Magel2 |
G |
A |
7: 62,030,188 (GRCm39) |
V1031I |
unknown |
Het |
| Man1c1 |
A |
T |
4: 134,308,100 (GRCm39) |
N338K |
probably benign |
Het |
| Mdn1 |
C |
A |
4: 32,739,977 (GRCm39) |
Q3744K |
probably damaging |
Het |
| Micu3 |
G |
T |
8: 40,788,893 (GRCm39) |
A135S |
possibly damaging |
Het |
| Muc4 |
T |
C |
16: 32,569,167 (GRCm39) |
S76P |
possibly damaging |
Het |
| Nin |
T |
G |
12: 70,061,547 (GRCm39) |
T2106P |
probably benign |
Het |
| Nlrp4e |
T |
C |
7: 23,021,268 (GRCm39) |
I585T |
probably benign |
Het |
| Npy1r |
C |
T |
8: 67,156,847 (GRCm39) |
A89V |
probably benign |
Het |
| Or11g27 |
T |
C |
14: 50,771,622 (GRCm39) |
V251A |
probably damaging |
Het |
| Or4c115 |
G |
A |
2: 88,927,944 (GRCm39) |
A109V |
probably benign |
Het |
| Or52ae7 |
T |
A |
7: 103,119,249 (GRCm39) |
M1K |
probably null |
Het |
| Or52n3 |
T |
A |
7: 104,530,515 (GRCm39) |
Y200* |
probably null |
Het |
| Or5w13 |
A |
T |
2: 87,523,872 (GRCm39) |
M118K |
probably damaging |
Het |
| Parp14 |
T |
G |
16: 35,677,008 (GRCm39) |
T987P |
possibly damaging |
Het |
| Pde7b |
A |
T |
10: 20,423,867 (GRCm39) |
V3E |
probably damaging |
Het |
| Pdlim7 |
G |
T |
13: 55,656,107 (GRCm39) |
Y104* |
probably null |
Het |
| Pgm2l1 |
A |
G |
7: 99,910,932 (GRCm39) |
K292R |
probably benign |
Het |
| Plec |
T |
C |
15: 76,072,401 (GRCm39) |
E728G |
probably damaging |
Het |
| Plppr4 |
T |
C |
3: 117,129,152 (GRCm39) |
Y105C |
probably damaging |
Het |
| Polr1c |
A |
T |
17: 46,558,821 (GRCm39) |
N23K |
possibly damaging |
Het |
| Ppp5c |
A |
T |
7: 16,743,861 (GRCm39) |
M191K |
probably damaging |
Het |
| Prkca |
T |
C |
11: 107,869,142 (GRCm39) |
D57G |
probably damaging |
Het |
| Prkcb |
A |
G |
7: 122,143,854 (GRCm39) |
|
probably null |
Het |
| Prl6a1 |
A |
T |
13: 27,502,911 (GRCm39) |
Q169L |
probably null |
Het |
| Prl6a1 |
C |
A |
13: 27,502,910 (GRCm39) |
Q169K |
possibly damaging |
Het |
| Psmd14 |
G |
A |
2: 61,591,335 (GRCm39) |
R46H |
probably damaging |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Ramp2 |
A |
G |
11: 101,138,408 (GRCm39) |
T22A |
probably benign |
Het |
| Rbm19 |
AGAGGAGGAGGAGGAGGAGGA |
AGAGGAGGAGGAGGAGGA |
5: 120,278,345 (GRCm39) |
|
probably benign |
Het |
| Rbm25 |
A |
T |
12: 83,715,219 (GRCm39) |
E463D |
possibly damaging |
Het |
| Retnlb |
A |
G |
16: 48,637,678 (GRCm39) |
I35V |
probably benign |
Het |
| Sestd1 |
A |
G |
2: 77,071,976 (GRCm39) |
Y49H |
probably damaging |
Het |
| Setd2 |
T |
A |
9: 110,431,306 (GRCm39) |
I2378N |
probably damaging |
Het |
| Slc26a1 |
A |
T |
5: 108,819,740 (GRCm39) |
C486* |
probably null |
Het |
| Spef2 |
T |
A |
15: 9,667,316 (GRCm39) |
I791F |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,650,798 (GRCm39) |
T1726A |
possibly damaging |
Het |
| Stk38l |
T |
A |
6: 146,673,129 (GRCm39) |
M296K |
probably benign |
Het |
| Taf5 |
T |
C |
19: 47,070,285 (GRCm39) |
F624L |
probably damaging |
Het |
| Tmem30c |
G |
T |
16: 57,086,855 (GRCm39) |
T316K |
probably damaging |
Het |
| Trpm2 |
A |
G |
10: 77,778,839 (GRCm39) |
S376P |
possibly damaging |
Het |
| Vmn2r82 |
A |
T |
10: 79,214,702 (GRCm39) |
L228F |
probably damaging |
Het |
| Zfp607b |
G |
A |
7: 27,398,087 (GRCm39) |
C57Y |
possibly damaging |
Het |
| Zfp983 |
A |
G |
17: 21,881,269 (GRCm39) |
H399R |
probably damaging |
Het |
| Zfp984 |
A |
T |
4: 147,840,002 (GRCm39) |
M283K |
probably benign |
Het |
|
| Other mutations in Dennd2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00493:Dennd2b
|
APN |
7 |
109,126,915 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01132:Dennd2b
|
APN |
7 |
109,169,212 (GRCm39) |
splice site |
probably null |
|
|
IGL01288:Dennd2b
|
APN |
7 |
109,139,029 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01645:Dennd2b
|
APN |
7 |
109,126,841 (GRCm39) |
nonsense |
probably null |
|
|
IGL01714:Dennd2b
|
APN |
7 |
109,169,269 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02021:Dennd2b
|
APN |
7 |
109,156,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02302:Dennd2b
|
APN |
7 |
109,124,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02496:Dennd2b
|
APN |
7 |
109,155,442 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL02795:Dennd2b
|
APN |
7 |
109,155,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Bucolic
|
UTSW |
7 |
109,124,755 (GRCm39) |
nonsense |
probably null |
|
|
Halcyon
|
UTSW |
7 |
109,156,000 (GRCm39) |
nonsense |
probably null |
|
|
FR4340:Dennd2b
|
UTSW |
7 |
109,156,128 (GRCm39) |
unclassified |
probably benign |
|
|
FR4737:Dennd2b
|
UTSW |
7 |
109,156,128 (GRCm39) |
unclassified |
probably benign |
|
|
PIT4466001:Dennd2b
|
UTSW |
7 |
109,130,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4469001:Dennd2b
|
UTSW |
7 |
109,130,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4472001:Dennd2b
|
UTSW |
7 |
109,130,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0024:Dennd2b
|
UTSW |
7 |
109,123,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0124:Dennd2b
|
UTSW |
7 |
109,141,718 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0125:Dennd2b
|
UTSW |
7 |
109,155,545 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0365:Dennd2b
|
UTSW |
7 |
109,138,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0491:Dennd2b
|
UTSW |
7 |
109,156,411 (GRCm39) |
missense |
probably benign |
0.45 |
|
R0534:Dennd2b
|
UTSW |
7 |
109,140,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0662:Dennd2b
|
UTSW |
7 |
109,156,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0743:Dennd2b
|
UTSW |
7 |
109,156,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0772:Dennd2b
|
UTSW |
7 |
109,141,527 (GRCm39) |
splice site |
probably null |
|
|
R0774:Dennd2b
|
UTSW |
7 |
109,141,527 (GRCm39) |
splice site |
probably null |
|
|
R0787:Dennd2b
|
UTSW |
7 |
109,124,827 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0884:Dennd2b
|
UTSW |
7 |
109,156,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1908:Dennd2b
|
UTSW |
7 |
109,124,533 (GRCm39) |
nonsense |
probably null |
|
|
R1909:Dennd2b
|
UTSW |
7 |
109,124,533 (GRCm39) |
nonsense |
probably null |
|
|
R2232:Dennd2b
|
UTSW |
7 |
109,156,414 (GRCm39) |
missense |
probably benign |
|
|
R2358:Dennd2b
|
UTSW |
7 |
109,155,653 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2847:Dennd2b
|
UTSW |
7 |
109,124,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2869:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2870:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2870:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2871:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2871:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2873:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2874:Dennd2b
|
UTSW |
7 |
109,156,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4534:Dennd2b
|
UTSW |
7 |
109,130,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4536:Dennd2b
|
UTSW |
7 |
109,130,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4559:Dennd2b
|
UTSW |
7 |
109,124,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4798:Dennd2b
|
UTSW |
7 |
109,156,240 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4846:Dennd2b
|
UTSW |
7 |
109,156,043 (GRCm39) |
nonsense |
probably null |
|
|
R5110:Dennd2b
|
UTSW |
7 |
109,141,697 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5181:Dennd2b
|
UTSW |
7 |
109,155,997 (GRCm39) |
missense |
probably benign |
|
|
R5268:Dennd2b
|
UTSW |
7 |
109,156,519 (GRCm39) |
missense |
probably benign |
|
|
R5403:Dennd2b
|
UTSW |
7 |
109,156,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5836:Dennd2b
|
UTSW |
7 |
109,140,552 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R5932:Dennd2b
|
UTSW |
7 |
109,169,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5937:Dennd2b
|
UTSW |
7 |
109,156,478 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6180:Dennd2b
|
UTSW |
7 |
109,156,095 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6741:Dennd2b
|
UTSW |
7 |
109,144,304 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6781:Dennd2b
|
UTSW |
7 |
109,124,511 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7086:Dennd2b
|
UTSW |
7 |
109,124,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Dennd2b
|
UTSW |
7 |
109,124,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7644:Dennd2b
|
UTSW |
7 |
109,156,000 (GRCm39) |
nonsense |
probably null |
|
|
R8354:Dennd2b
|
UTSW |
7 |
109,124,755 (GRCm39) |
nonsense |
probably null |
|
|
R8745:Dennd2b
|
UTSW |
7 |
109,156,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8859:Dennd2b
|
UTSW |
7 |
109,123,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9016:Dennd2b
|
UTSW |
7 |
109,139,642 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9178:Dennd2b
|
UTSW |
7 |
109,156,291 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9361:Dennd2b
|
UTSW |
7 |
109,126,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9564:Dennd2b
|
UTSW |
7 |
109,125,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9595:Dennd2b
|
UTSW |
7 |
109,155,973 (GRCm39) |
missense |
probably damaging |
0.96 |
|
RF062:Dennd2b
|
UTSW |
7 |
109,156,153 (GRCm39) |
unclassified |
probably benign |
|
|
X0067:Dennd2b
|
UTSW |
7 |
109,155,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACAGACTCATCCTGGGTGAAGC -3'
(R):5'- GCCTGCCGTGACTAAAGAGCTATTC -3'
Sequencing Primer
(F):5'- TCTCGGATACCCAGGCTATG -3'
(R):5'- aatcctcttgccttcatctcc -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation