Incidental Mutation 'R1518:Parp14'
| ID |
167228 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Parp14
|
| Ensembl Gene |
ENSMUSG00000034422 |
| Gene Name |
poly (ADP-ribose) polymerase family, member 14 |
| Synonyms |
CoaSt6, collaborator of Stat6, 1600029O10Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.493)
|
| Stock # |
R1518 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
35653244-35691914 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 35677008 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Proline
at position 987
(T987P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037657
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042665]
|
| AlphaFold |
Q2EMV9 |
| PDB Structure |
Solution structure of WWE domain in Parp14 protein [SOLUTION NMR]
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000042665
AA Change: T987P
PolyPhen 2
Score 0.792 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000037657
Gene: ENSMUSG00000034422
AA Change: T987P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
49 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
115 |
N/A |
INTRINSIC |
|
RRM
|
228 |
297 |
4.71e-2 |
SMART |
|
coiled coil region
|
443 |
468 |
N/A |
INTRINSIC |
|
Blast:A1pp
|
693 |
746 |
6e-6 |
BLAST |
|
low complexity region
|
771 |
795 |
N/A |
INTRINSIC |
|
A1pp
|
814 |
948 |
7.62e-41 |
SMART |
|
A1pp
|
1026 |
1160 |
5.88e-24 |
SMART |
|
A1pp
|
1239 |
1358 |
6.82e-20 |
SMART |
|
PDB:1X4R|A
|
1532 |
1619 |
9e-53 |
PDB |
|
Pfam:PARP
|
1632 |
1817 |
2.5e-29 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142946
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit altered B cell subsets and inability to respond to the apoptosis protective affects of IL4. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg4 |
T |
A |
9: 44,186,666 (GRCm39) |
M493L |
probably benign |
Het |
| Abtb2 |
G |
A |
2: 103,539,629 (GRCm39) |
V665I |
probably benign |
Het |
| Adamtsl1 |
C |
G |
4: 86,260,840 (GRCm39) |
S1017W |
probably damaging |
Het |
| Aebp1 |
A |
G |
11: 5,821,469 (GRCm39) |
T623A |
possibly damaging |
Het |
| Alox5 |
A |
G |
6: 116,390,741 (GRCm39) |
F470S |
probably damaging |
Het |
| Angpt2 |
T |
C |
8: 18,755,855 (GRCm39) |
E204G |
probably benign |
Het |
| Apip |
A |
G |
2: 102,919,838 (GRCm39) |
E138G |
probably damaging |
Het |
| Apob |
C |
T |
12: 8,039,207 (GRCm39) |
T466M |
probably benign |
Het |
| Atp2b3 |
GACAACA |
GACA |
X: 72,588,729 (GRCm39) |
|
probably benign |
Het |
| Atxn7l3 |
A |
T |
11: 102,185,340 (GRCm39) |
D56E |
probably benign |
Het |
| Cacna1s |
C |
T |
1: 136,026,289 (GRCm39) |
A1092V |
probably damaging |
Het |
| Calr3 |
A |
G |
8: 73,181,044 (GRCm39) |
F183L |
probably damaging |
Het |
| Cd300lb |
T |
A |
11: 114,816,877 (GRCm39) |
D55V |
probably benign |
Het |
| Chid1 |
A |
C |
7: 141,108,384 (GRCm39) |
V145G |
probably damaging |
Het |
| Chst15 |
T |
C |
7: 131,871,855 (GRCm39) |
N142S |
probably damaging |
Het |
| Cnot4 |
C |
T |
6: 35,028,389 (GRCm39) |
R409Q |
probably damaging |
Het |
| Cope |
T |
G |
8: 70,765,411 (GRCm39) |
I287S |
possibly damaging |
Het |
| Cpd |
A |
T |
11: 76,731,212 (GRCm39) |
|
probably null |
Het |
| Cux1 |
G |
T |
5: 136,337,133 (GRCm39) |
T785K |
probably benign |
Het |
| Dennd2b |
A |
G |
7: 109,156,562 (GRCm39) |
S63P |
probably damaging |
Het |
| Dthd1 |
T |
C |
5: 62,979,383 (GRCm39) |
S348P |
probably damaging |
Het |
| Eno3 |
G |
T |
11: 70,551,903 (GRCm39) |
E64* |
probably null |
Het |
| Entpd1 |
T |
A |
19: 40,713,507 (GRCm39) |
Y184* |
probably null |
Het |
| Erv3 |
A |
T |
2: 131,698,083 (GRCm39) |
M92K |
probably benign |
Het |
| Flg2 |
T |
A |
3: 93,110,445 (GRCm39) |
H824Q |
unknown |
Het |
| Fndc9 |
G |
A |
11: 46,128,930 (GRCm39) |
G150S |
probably benign |
Het |
| Gdap1 |
G |
A |
1: 17,217,169 (GRCm39) |
V43I |
possibly damaging |
Het |
| Ifi213 |
C |
A |
1: 173,417,229 (GRCm39) |
L394F |
probably damaging |
Het |
| Ift88 |
A |
G |
14: 57,668,085 (GRCm39) |
T29A |
possibly damaging |
Het |
| Kdm4c |
A |
T |
4: 74,252,063 (GRCm39) |
I437L |
probably benign |
Het |
| Kras |
T |
A |
6: 145,177,977 (GRCm39) |
E98D |
probably benign |
Het |
| Lcorl |
C |
A |
5: 45,891,543 (GRCm39) |
R353I |
possibly damaging |
Het |
| Lrrc4c |
A |
G |
2: 97,460,921 (GRCm39) |
I516V |
probably benign |
Het |
| Lrrc51 |
T |
C |
7: 101,564,803 (GRCm39) |
D85G |
probably damaging |
Het |
| Lypd6b |
G |
A |
2: 49,837,504 (GRCm39) |
A159T |
probably damaging |
Het |
| Magel2 |
G |
A |
7: 62,030,188 (GRCm39) |
V1031I |
unknown |
Het |
| Man1c1 |
A |
T |
4: 134,308,100 (GRCm39) |
N338K |
probably benign |
Het |
| Mdn1 |
C |
A |
4: 32,739,977 (GRCm39) |
Q3744K |
probably damaging |
Het |
| Micu3 |
G |
T |
8: 40,788,893 (GRCm39) |
A135S |
possibly damaging |
Het |
| Muc4 |
T |
C |
16: 32,569,167 (GRCm39) |
S76P |
possibly damaging |
Het |
| Nin |
T |
G |
12: 70,061,547 (GRCm39) |
T2106P |
probably benign |
Het |
| Nlrp4e |
T |
C |
7: 23,021,268 (GRCm39) |
I585T |
probably benign |
Het |
| Npy1r |
C |
T |
8: 67,156,847 (GRCm39) |
A89V |
probably benign |
Het |
| Or11g27 |
T |
C |
14: 50,771,622 (GRCm39) |
V251A |
probably damaging |
Het |
| Or4c115 |
G |
A |
2: 88,927,944 (GRCm39) |
A109V |
probably benign |
Het |
| Or52ae7 |
T |
A |
7: 103,119,249 (GRCm39) |
M1K |
probably null |
Het |
| Or52n3 |
T |
A |
7: 104,530,515 (GRCm39) |
Y200* |
probably null |
Het |
| Or5w13 |
A |
T |
2: 87,523,872 (GRCm39) |
M118K |
probably damaging |
Het |
| Pde7b |
A |
T |
10: 20,423,867 (GRCm39) |
V3E |
probably damaging |
Het |
| Pdlim7 |
G |
T |
13: 55,656,107 (GRCm39) |
Y104* |
probably null |
Het |
| Pgm2l1 |
A |
G |
7: 99,910,932 (GRCm39) |
K292R |
probably benign |
Het |
| Plec |
T |
C |
15: 76,072,401 (GRCm39) |
E728G |
probably damaging |
Het |
| Plppr4 |
T |
C |
3: 117,129,152 (GRCm39) |
Y105C |
probably damaging |
Het |
| Polr1c |
A |
T |
17: 46,558,821 (GRCm39) |
N23K |
possibly damaging |
Het |
| Ppp5c |
A |
T |
7: 16,743,861 (GRCm39) |
M191K |
probably damaging |
Het |
| Prkca |
T |
C |
11: 107,869,142 (GRCm39) |
D57G |
probably damaging |
Het |
| Prkcb |
A |
G |
7: 122,143,854 (GRCm39) |
|
probably null |
Het |
| Prl6a1 |
A |
T |
13: 27,502,911 (GRCm39) |
Q169L |
probably null |
Het |
| Prl6a1 |
C |
A |
13: 27,502,910 (GRCm39) |
Q169K |
possibly damaging |
Het |
| Psmd14 |
G |
A |
2: 61,591,335 (GRCm39) |
R46H |
probably damaging |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Ramp2 |
A |
G |
11: 101,138,408 (GRCm39) |
T22A |
probably benign |
Het |
| Rbm19 |
AGAGGAGGAGGAGGAGGAGGA |
AGAGGAGGAGGAGGAGGA |
5: 120,278,345 (GRCm39) |
|
probably benign |
Het |
| Rbm25 |
A |
T |
12: 83,715,219 (GRCm39) |
E463D |
possibly damaging |
Het |
| Retnlb |
A |
G |
16: 48,637,678 (GRCm39) |
I35V |
probably benign |
Het |
| Sestd1 |
A |
G |
2: 77,071,976 (GRCm39) |
Y49H |
probably damaging |
Het |
| Setd2 |
T |
A |
9: 110,431,306 (GRCm39) |
I2378N |
probably damaging |
Het |
| Slc26a1 |
A |
T |
5: 108,819,740 (GRCm39) |
C486* |
probably null |
Het |
| Spef2 |
T |
A |
15: 9,667,316 (GRCm39) |
I791F |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,650,798 (GRCm39) |
T1726A |
possibly damaging |
Het |
| Stk38l |
T |
A |
6: 146,673,129 (GRCm39) |
M296K |
probably benign |
Het |
| Taf5 |
T |
C |
19: 47,070,285 (GRCm39) |
F624L |
probably damaging |
Het |
| Tmem30c |
G |
T |
16: 57,086,855 (GRCm39) |
T316K |
probably damaging |
Het |
| Trpm2 |
A |
G |
10: 77,778,839 (GRCm39) |
S376P |
possibly damaging |
Het |
| Vmn2r82 |
A |
T |
10: 79,214,702 (GRCm39) |
L228F |
probably damaging |
Het |
| Zfp607b |
G |
A |
7: 27,398,087 (GRCm39) |
C57Y |
possibly damaging |
Het |
| Zfp983 |
A |
G |
17: 21,881,269 (GRCm39) |
H399R |
probably damaging |
Het |
| Zfp984 |
A |
T |
4: 147,840,002 (GRCm39) |
M283K |
probably benign |
Het |
|
| Other mutations in Parp14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Parp14
|
APN |
16 |
35,661,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00497:Parp14
|
APN |
16 |
35,655,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00754:Parp14
|
APN |
16 |
35,659,741 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00960:Parp14
|
APN |
16 |
35,661,589 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01321:Parp14
|
APN |
16 |
35,676,929 (GRCm39) |
missense |
probably benign |
|
|
IGL01397:Parp14
|
APN |
16 |
35,679,098 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01591:Parp14
|
APN |
16 |
35,678,877 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01728:Parp14
|
APN |
16 |
35,677,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01734:Parp14
|
APN |
16 |
35,678,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02156:Parp14
|
APN |
16 |
35,678,967 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02951:Parp14
|
APN |
16 |
35,678,903 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03067:Parp14
|
APN |
16 |
35,676,878 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03135:Parp14
|
APN |
16 |
35,678,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03141:Parp14
|
APN |
16 |
35,659,663 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03146:Parp14
|
APN |
16 |
35,678,823 (GRCm39) |
nonsense |
probably null |
|
|
IGL03333:Parp14
|
APN |
16 |
35,661,800 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03391:Parp14
|
APN |
16 |
35,678,640 (GRCm39) |
missense |
probably benign |
|
|
thurston
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
PIT4585001:Parp14
|
UTSW |
16 |
35,678,975 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0306:Parp14
|
UTSW |
16 |
35,676,944 (GRCm39) |
missense |
probably benign |
|
|
R0506:Parp14
|
UTSW |
16 |
35,661,779 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R0586:Parp14
|
UTSW |
16 |
35,661,382 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0606:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0612:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0699:Parp14
|
UTSW |
16 |
35,680,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0786:Parp14
|
UTSW |
16 |
35,661,172 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0883:Parp14
|
UTSW |
16 |
35,678,888 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0900:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1087:Parp14
|
UTSW |
16 |
35,678,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Parp14
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
R1120:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1134:Parp14
|
UTSW |
16 |
35,655,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1153:Parp14
|
UTSW |
16 |
35,678,041 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1159:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1160:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1237:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1238:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1239:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1423:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1511:Parp14
|
UTSW |
16 |
35,677,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1619:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1707:Parp14
|
UTSW |
16 |
35,678,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1792:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1831:Parp14
|
UTSW |
16 |
35,678,958 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1840:Parp14
|
UTSW |
16 |
35,683,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1902:Parp14
|
UTSW |
16 |
35,673,888 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1943:Parp14
|
UTSW |
16 |
35,656,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Parp14
|
UTSW |
16 |
35,678,671 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2115:Parp14
|
UTSW |
16 |
35,678,904 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2216:Parp14
|
UTSW |
16 |
35,677,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2519:Parp14
|
UTSW |
16 |
35,678,573 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3851:Parp14
|
UTSW |
16 |
35,674,118 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4052:Parp14
|
UTSW |
16 |
35,678,771 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4671:Parp14
|
UTSW |
16 |
35,678,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4867:Parp14
|
UTSW |
16 |
35,677,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4941:Parp14
|
UTSW |
16 |
35,666,403 (GRCm39) |
missense |
probably benign |
|
|
R4992:Parp14
|
UTSW |
16 |
35,661,512 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5055:Parp14
|
UTSW |
16 |
35,664,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5073:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5170:Parp14
|
UTSW |
16 |
35,677,649 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5422:Parp14
|
UTSW |
16 |
35,686,545 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5543:Parp14
|
UTSW |
16 |
35,655,137 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5549:Parp14
|
UTSW |
16 |
35,661,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5553:Parp14
|
UTSW |
16 |
35,677,306 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5691:Parp14
|
UTSW |
16 |
35,683,909 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5774:Parp14
|
UTSW |
16 |
35,678,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5855:Parp14
|
UTSW |
16 |
35,661,297 (GRCm39) |
nonsense |
probably null |
|
|
R5942:Parp14
|
UTSW |
16 |
35,659,737 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5990:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5991:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6018:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6022:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6075:Parp14
|
UTSW |
16 |
35,677,389 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6395:Parp14
|
UTSW |
16 |
35,676,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6525:Parp14
|
UTSW |
16 |
35,680,811 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6683:Parp14
|
UTSW |
16 |
35,655,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7525:Parp14
|
UTSW |
16 |
35,677,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8011:Parp14
|
UTSW |
16 |
35,677,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8192:Parp14
|
UTSW |
16 |
35,691,584 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8367:Parp14
|
UTSW |
16 |
35,678,124 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8526:Parp14
|
UTSW |
16 |
35,661,307 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8751:Parp14
|
UTSW |
16 |
35,677,181 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8962:Parp14
|
UTSW |
16 |
35,677,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Parp14
|
UTSW |
16 |
35,661,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9363:Parp14
|
UTSW |
16 |
35,678,586 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9366:Parp14
|
UTSW |
16 |
35,659,630 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9379:Parp14
|
UTSW |
16 |
35,680,853 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9562:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9565:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,252 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,251 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0026:Parp14
|
UTSW |
16 |
35,677,527 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Parp14
|
UTSW |
16 |
35,661,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,665,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,691,573 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTACCGTAGCATTCTGCACGCC -3'
(R):5'- CTGGAGTGTGTGAGCCTGCTAAAG -3'
Sequencing Primer
(F):5'- GCCTTCTTCTACCAGGCGG -3'
(R):5'- CCTGCTAAAGAAAGTGGTTAGAC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation