Incidental Mutation 'R1511:Eml6'
| ID |
168345 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Eml6
|
| Ensembl Gene |
ENSMUSG00000044072 |
| Gene Name |
echinoderm microtubule associated protein like 6 |
| Synonyms |
|
| MMRRC Submission |
039558-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.223)
|
| Stock # |
R1511 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
29743048-30026033 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 29818374 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 771
(H771L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051080
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058902]
[ENSMUST00000104962]
|
| AlphaFold |
Q5SQM0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000058902
AA Change: H771L
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000051080
Gene: ENSMUSG00000044072
AA Change: H771L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
36 |
47 |
N/A |
INTRINSIC |
|
WD40
|
49 |
91 |
1.79e-1 |
SMART |
|
WD40
|
94 |
136 |
1.42e-4 |
SMART |
|
WD40
|
139 |
178 |
5.31e-4 |
SMART |
|
WD40
|
184 |
224 |
8.84e1 |
SMART |
|
WD40
|
225 |
263 |
3.75e-4 |
SMART |
|
WD40
|
313 |
353 |
4.69e-5 |
SMART |
|
WD40
|
356 |
394 |
2.22e0 |
SMART |
|
WD40
|
397 |
436 |
1.72e0 |
SMART |
|
WD40
|
505 |
546 |
1.7e2 |
SMART |
|
WD40
|
552 |
592 |
4.55e-3 |
SMART |
|
low complexity region
|
613 |
625 |
N/A |
INTRINSIC |
|
Pfam:HELP
|
653 |
715 |
1.9e-22 |
PFAM |
|
WD40
|
716 |
757 |
9.24e-1 |
SMART |
|
WD40
|
760 |
802 |
6.53e-4 |
SMART |
|
WD40
|
805 |
844 |
2.98e-1 |
SMART |
|
WD40
|
856 |
891 |
8.52e1 |
SMART |
|
WD40
|
892 |
929 |
2.09e-2 |
SMART |
|
WD40
|
986 |
1026 |
1.18e-1 |
SMART |
|
WD40
|
1032 |
1068 |
3.44e0 |
SMART |
|
WD40
|
1071 |
1111 |
2.58e-1 |
SMART |
|
WD40
|
1180 |
1221 |
9.24e-1 |
SMART |
|
WD40
|
1227 |
1267 |
3.85e-1 |
SMART |
|
low complexity region
|
1280 |
1291 |
N/A |
INTRINSIC |
|
Pfam:HELP
|
1329 |
1402 |
5e-15 |
PFAM |
|
WD40
|
1404 |
1447 |
2.66e0 |
SMART |
|
WD40
|
1450 |
1492 |
1.85e0 |
SMART |
|
WD40
|
1495 |
1534 |
2.97e0 |
SMART |
|
WD40
|
1543 |
1582 |
7.1e1 |
SMART |
|
WD40
|
1584 |
1629 |
9.51e1 |
SMART |
|
WD40
|
1675 |
1715 |
3.05e-4 |
SMART |
|
WD40
|
1718 |
1758 |
8.84e1 |
SMART |
|
WD40
|
1759 |
1798 |
7.16e-1 |
SMART |
|
WD40
|
1869 |
1910 |
1.53e1 |
SMART |
|
WD40
|
1916 |
1956 |
4.62e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000104962
|
| SMART Domains |
Protein: ENSMUSP00000100568
Gene: ENSMUSG00000078157
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
19 |
50 |
1.53e3 |
SMART |
|
ANK
|
57 |
87 |
1.7e-3 |
SMART |
|
ANK
|
99 |
128 |
3.6e-2 |
SMART |
|
ANK
|
132 |
162 |
3.31e-1 |
SMART |
|
ANK
|
166 |
195 |
8.19e-6 |
SMART |
|
ANK
|
199 |
228 |
7.83e-3 |
SMART |
|
ANK
|
231 |
260 |
1.8e-2 |
SMART |
|
low complexity region
|
297 |
306 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
445 |
N/A |
INTRINSIC |
|
low complexity region
|
496 |
507 |
N/A |
INTRINSIC |
|
ANK
|
536 |
578 |
8.39e-3 |
SMART |
|
ANK
|
582 |
611 |
3.91e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109452
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 95.4%
- 20x: 89.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aacs |
C |
A |
5: 125,514,977 (GRCm38) |
N576K |
probably benign |
Het |
| Abca5 |
T |
A |
11: 110,299,986 (GRCm38) |
H766L |
possibly damaging |
Het |
| Abca5 |
G |
T |
11: 110,299,978 (GRCm38) |
L769M |
probably damaging |
Het |
| Acvr1c |
A |
G |
2: 58,287,884 (GRCm38) |
I191T |
probably damaging |
Het |
| Agps |
A |
T |
2: 75,866,779 (GRCm38) |
E314D |
probably damaging |
Het |
| Agxt |
G |
A |
1: 93,135,768 (GRCm38) |
G131R |
probably damaging |
Het |
| Ak8 |
A |
G |
2: 28,742,746 (GRCm38) |
T326A |
probably benign |
Het |
| Aldoart2 |
T |
A |
12: 55,566,277 (GRCm38) |
I329N |
probably benign |
Het |
| Apaf1 |
T |
C |
10: 91,060,185 (GRCm38) |
I342V |
possibly damaging |
Het |
| Arhgap40 |
T |
C |
2: 158,527,161 (GRCm38) |
S68P |
probably benign |
Het |
| Arsi |
G |
A |
18: 60,916,651 (GRCm38) |
G202E |
probably benign |
Het |
| AU022252 |
C |
T |
4: 119,228,097 (GRCm38) |
R71Q |
possibly damaging |
Het |
| Baz1b |
T |
C |
5: 135,217,782 (GRCm38) |
L695P |
probably damaging |
Het |
| Baz2b |
A |
T |
2: 59,962,024 (GRCm38) |
S587T |
probably benign |
Het |
| Cep76 |
T |
C |
18: 67,624,958 (GRCm38) |
M421V |
probably benign |
Het |
| Clk2 |
A |
G |
3: 89,168,703 (GRCm38) |
D60G |
probably damaging |
Het |
| Clstn3 |
G |
T |
6: 124,462,169 (GRCm38) |
T6K |
probably damaging |
Het |
| Cluap1 |
T |
A |
16: 3,919,558 (GRCm38) |
D180E |
probably benign |
Het |
| Col12a1 |
T |
C |
9: 79,699,552 (GRCm38) |
I530V |
probably benign |
Het |
| Cpt1a |
T |
C |
19: 3,365,788 (GRCm38) |
|
probably benign |
Het |
| Cr2 |
T |
G |
1: 195,155,272 (GRCm38) |
K797Q |
possibly damaging |
Het |
| Crybg3 |
C |
A |
16: 59,554,112 (GRCm38) |
V2260L |
probably benign |
Het |
| Csnk1a1 |
T |
A |
18: 61,585,250 (GRCm38) |
|
probably benign |
Het |
| Cxcr1 |
T |
C |
1: 74,192,770 (GRCm38) |
D31G |
probably benign |
Het |
| Cyp2a5 |
G |
T |
7: 26,835,936 (GRCm38) |
D108Y |
probably damaging |
Het |
| Dnajc1 |
A |
G |
2: 18,222,727 (GRCm38) |
V376A |
possibly damaging |
Het |
| Eif4enif1 |
T |
C |
11: 3,236,278 (GRCm38) |
V462A |
probably benign |
Het |
| Elmo1 |
A |
G |
13: 20,290,477 (GRCm38) |
K357R |
possibly damaging |
Het |
| Epb41l4a |
A |
G |
18: 33,832,664 (GRCm38) |
I370T |
probably benign |
Het |
| Esp36 |
A |
T |
17: 38,417,281 (GRCm38) |
N79K |
possibly damaging |
Het |
| Fam229b |
A |
G |
10: 39,118,919 (GRCm38) |
*81Q |
probably null |
Het |
| Fat4 |
T |
C |
3: 38,983,076 (GRCm38) |
Y3626H |
probably damaging |
Het |
| Fbn1 |
A |
T |
2: 125,306,285 (GRCm38) |
F2681Y |
probably benign |
Het |
| Gad1-ps |
A |
G |
10: 99,445,469 (GRCm38) |
|
noncoding transcript |
Het |
| Galm |
C |
A |
17: 80,183,267 (GRCm38) |
N284K |
probably damaging |
Het |
| Gtf3c2 |
A |
T |
5: 31,159,102 (GRCm38) |
S735T |
probably benign |
Het |
| Hsph1 |
A |
T |
5: 149,630,383 (GRCm38) |
S207T |
probably benign |
Het |
| Il33 |
C |
T |
19: 29,955,215 (GRCm38) |
R159C |
probably damaging |
Het |
| Invs |
A |
G |
4: 48,382,148 (GRCm38) |
N106S |
possibly damaging |
Het |
| Kif21b |
G |
T |
1: 136,169,324 (GRCm38) |
|
probably null |
Het |
| Kirrel2 |
A |
G |
7: 30,456,498 (GRCm38) |
C42R |
probably damaging |
Het |
| Letm1 |
A |
C |
5: 33,752,555 (GRCm38) |
C378W |
probably damaging |
Het |
| Lrrc71 |
T |
A |
3: 87,745,484 (GRCm38) |
K160N |
probably benign |
Het |
| Lrrtm3 |
A |
G |
10: 64,089,025 (GRCm38) |
I121T |
probably damaging |
Het |
| Lztr1 |
T |
A |
16: 17,509,670 (GRCm38) |
V79E |
probably damaging |
Het |
| Mmp8 |
T |
G |
9: 7,566,278 (GRCm38) |
D378E |
probably damaging |
Het |
| Mpzl3 |
A |
G |
9: 45,066,529 (GRCm38) |
E145G |
probably damaging |
Het |
| Mrps2 |
C |
T |
2: 28,469,664 (GRCm38) |
L178F |
probably damaging |
Het |
| Mzb1 |
A |
G |
18: 35,647,822 (GRCm38) |
|
probably null |
Het |
| Nckap1 |
T |
C |
2: 80,553,415 (GRCm38) |
D135G |
probably damaging |
Het |
| Ndst1 |
A |
G |
18: 60,697,170 (GRCm38) |
F623L |
possibly damaging |
Het |
| Nlrp5 |
A |
T |
7: 23,413,347 (GRCm38) |
D143V |
probably damaging |
Het |
| Olfr1225 |
A |
G |
2: 89,170,937 (GRCm38) |
S92P |
probably damaging |
Het |
| Olfr1241 |
T |
C |
2: 89,482,248 (GRCm38) |
M296V |
probably null |
Het |
| Olfr1311 |
A |
G |
2: 112,021,404 (GRCm38) |
V150A |
probably benign |
Het |
| Olfr146 |
T |
C |
9: 39,019,025 (GRCm38) |
D172G |
probably benign |
Het |
| Olfr307 |
T |
C |
7: 86,336,345 (GRCm38) |
D17G |
possibly damaging |
Het |
| Olfr32 |
A |
G |
2: 90,138,404 (GRCm38) |
V245A |
probably benign |
Het |
| Olfr548-ps1 |
T |
C |
7: 102,542,125 (GRCm38) |
L63P |
probably damaging |
Het |
| Olfr907 |
A |
G |
9: 38,498,818 (GRCm38) |
I50V |
probably benign |
Het |
| Parp14 |
T |
G |
16: 35,857,224 (GRCm38) |
E791D |
probably benign |
Het |
| Pcdh8 |
C |
T |
14: 79,769,389 (GRCm38) |
R578H |
possibly damaging |
Het |
| Phrf1 |
T |
A |
7: 141,259,801 (GRCm38) |
|
probably benign |
Het |
| Polr3b |
C |
A |
10: 84,680,385 (GRCm38) |
H626N |
probably benign |
Het |
| Ppp1r12a |
A |
G |
10: 108,251,859 (GRCm38) |
T58A |
probably benign |
Het |
| Ppp4r3b |
T |
A |
11: 29,182,460 (GRCm38) |
V33D |
probably damaging |
Het |
| Ppp5c |
A |
G |
7: 17,009,982 (GRCm38) |
Y176H |
probably damaging |
Het |
| R3hdm1 |
A |
G |
1: 128,197,005 (GRCm38) |
Y343C |
probably damaging |
Het |
| Rabac1 |
C |
T |
7: 24,972,130 (GRCm38) |
V122M |
probably damaging |
Het |
| Rasef |
G |
T |
4: 73,735,748 (GRCm38) |
Q561K |
probably damaging |
Het |
| Rbl1 |
A |
G |
2: 157,195,634 (GRCm38) |
S198P |
probably damaging |
Het |
| Rbm12 |
A |
T |
2: 156,097,536 (GRCm38) |
M272K |
probably damaging |
Het |
| Rexo1 |
T |
G |
10: 80,550,050 (GRCm38) |
K391N |
possibly damaging |
Het |
| Rnf43 |
T |
C |
11: 87,731,347 (GRCm38) |
S384P |
probably benign |
Het |
| Rpsa |
A |
T |
9: 120,131,000 (GRCm38) |
I210F |
possibly damaging |
Het |
| Rslcan18 |
A |
G |
13: 67,098,952 (GRCm38) |
Y75H |
possibly damaging |
Het |
| Scn9a |
T |
A |
2: 66,526,813 (GRCm38) |
D1048V |
probably benign |
Het |
| Sec11a |
T |
C |
7: 80,927,734 (GRCm38) |
|
probably null |
Het |
| Sidt2 |
A |
G |
9: 45,950,089 (GRCm38) |
V19A |
probably damaging |
Het |
| Snx14 |
G |
A |
9: 88,398,364 (GRCm38) |
Q522* |
probably null |
Het |
| Stx1b |
A |
G |
7: 127,814,972 (GRCm38) |
L74S |
probably damaging |
Het |
| Tm7sf3 |
A |
T |
6: 146,609,878 (GRCm38) |
M371K |
probably benign |
Het |
| Tmem115 |
T |
C |
9: 107,534,975 (GRCm38) |
V166A |
probably benign |
Het |
| Traf5 |
T |
A |
1: 191,999,951 (GRCm38) |
T310S |
probably benign |
Het |
| Trdn |
A |
G |
10: 33,466,452 (GRCm38) |
K619E |
probably benign |
Het |
| Trmt10a |
T |
A |
3: 138,152,184 (GRCm38) |
|
probably null |
Het |
| Txk |
A |
C |
5: 72,707,671 (GRCm38) |
I287R |
probably damaging |
Het |
| Txndc16 |
T |
C |
14: 45,151,887 (GRCm38) |
D452G |
probably damaging |
Het |
| Ube2f |
G |
A |
1: 91,262,301 (GRCm38) |
|
probably null |
Het |
| Ubtfl1 |
T |
G |
9: 18,410,193 (GRCm38) |
I339R |
probably benign |
Het |
| Upf1 |
A |
G |
8: 70,338,505 (GRCm38) |
I529T |
probably damaging |
Het |
| Vmn1r197 |
A |
G |
13: 22,328,653 (GRCm38) |
D248G |
possibly damaging |
Het |
| Vmn1r5 |
A |
T |
6: 56,985,786 (GRCm38) |
T149S |
probably benign |
Het |
| Vmn1r83 |
C |
T |
7: 12,321,270 (GRCm38) |
V287I |
possibly damaging |
Het |
| Vmn2r118 |
G |
A |
17: 55,608,496 (GRCm38) |
R485* |
probably null |
Het |
| Vmn2r-ps130 |
A |
G |
17: 23,063,801 (GRCm38) |
T152A |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,839,975 (GRCm38) |
F2448L |
probably damaging |
Het |
| Vps13b |
A |
G |
15: 35,841,573 (GRCm38) |
N2583S |
probably benign |
Het |
| Wscd1 |
C |
T |
11: 71,788,675 (GRCm38) |
P458L |
probably damaging |
Het |
| Xylt2 |
T |
A |
11: 94,670,433 (GRCm38) |
D168V |
probably damaging |
Het |
| Zdhhc2 |
A |
G |
8: 40,467,972 (GRCm38) |
T306A |
probably benign |
Het |
| Zfp804b |
A |
T |
5: 6,769,771 (GRCm38) |
D1097E |
possibly damaging |
Het |
| Zfp93 |
T |
A |
7: 24,275,731 (GRCm38) |
C380* |
probably null |
Het |
| Zfp960 |
T |
A |
17: 17,088,256 (GRCm38) |
C411S |
probably damaging |
Het |
| Zmynd15 |
T |
A |
11: 70,464,793 (GRCm38) |
V430E |
probably damaging |
Het |
|
| Other mutations in Eml6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01071:Eml6
|
APN |
11 |
29,850,816 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01407:Eml6
|
APN |
11 |
29,755,021 (GRCm38) |
nonsense |
probably null |
|
|
IGL01434:Eml6
|
APN |
11 |
29,819,090 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01578:Eml6
|
APN |
11 |
29,850,870 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL01780:Eml6
|
APN |
11 |
29,805,175 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01821:Eml6
|
APN |
11 |
29,821,699 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01837:Eml6
|
APN |
11 |
29,777,055 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01904:Eml6
|
APN |
11 |
29,838,613 (GRCm38) |
nonsense |
probably null |
|
|
IGL01972:Eml6
|
APN |
11 |
29,838,451 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
IGL02134:Eml6
|
APN |
11 |
29,759,066 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02192:Eml6
|
APN |
11 |
29,805,743 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02377:Eml6
|
APN |
11 |
29,777,282 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02584:Eml6
|
APN |
11 |
29,749,387 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02587:Eml6
|
APN |
11 |
29,784,236 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02810:Eml6
|
APN |
11 |
29,849,016 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02873:Eml6
|
APN |
11 |
29,880,700 (GRCm38) |
missense |
probably benign |
0.10 |
|
IGL02880:Eml6
|
APN |
11 |
29,749,959 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL03289:Eml6
|
APN |
11 |
29,795,328 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL03301:Eml6
|
APN |
11 |
29,764,083 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL03386:Eml6
|
APN |
11 |
29,749,934 (GRCm38) |
missense |
probably benign |
|
|
IGL03407:Eml6
|
APN |
11 |
29,906,330 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Eml6
|
UTSW |
11 |
29,802,489 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0125:Eml6
|
UTSW |
11 |
29,882,088 (GRCm38) |
missense |
probably benign |
0.19 |
|
R0240:Eml6
|
UTSW |
11 |
29,792,367 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R0240:Eml6
|
UTSW |
11 |
29,792,367 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R0271:Eml6
|
UTSW |
11 |
29,848,949 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R0304:Eml6
|
UTSW |
11 |
29,777,441 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0415:Eml6
|
UTSW |
11 |
29,749,392 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R0449:Eml6
|
UTSW |
11 |
29,893,213 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0538:Eml6
|
UTSW |
11 |
29,760,010 (GRCm38) |
splice site |
probably benign |
|
|
R0671:Eml6
|
UTSW |
11 |
29,805,065 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0766:Eml6
|
UTSW |
11 |
29,831,219 (GRCm38) |
splice site |
probably benign |
|
|
R0800:Eml6
|
UTSW |
11 |
29,749,877 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0841:Eml6
|
UTSW |
11 |
29,777,430 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0879:Eml6
|
UTSW |
11 |
29,850,816 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1061:Eml6
|
UTSW |
11 |
29,777,267 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1145:Eml6
|
UTSW |
11 |
29,777,430 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1145:Eml6
|
UTSW |
11 |
29,777,430 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1172:Eml6
|
UTSW |
11 |
29,749,824 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R1173:Eml6
|
UTSW |
11 |
29,749,824 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R1174:Eml6
|
UTSW |
11 |
29,749,824 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R1199:Eml6
|
UTSW |
11 |
29,755,044 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1311:Eml6
|
UTSW |
11 |
29,831,088 (GRCm38) |
splice site |
probably benign |
|
|
R1312:Eml6
|
UTSW |
11 |
29,831,219 (GRCm38) |
splice site |
probably benign |
|
|
R1355:Eml6
|
UTSW |
11 |
29,833,085 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1370:Eml6
|
UTSW |
11 |
29,833,085 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1457:Eml6
|
UTSW |
11 |
30,024,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1486:Eml6
|
UTSW |
11 |
29,805,114 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R1532:Eml6
|
UTSW |
11 |
29,792,256 (GRCm38) |
splice site |
probably null |
|
|
R1642:Eml6
|
UTSW |
11 |
29,777,001 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1682:Eml6
|
UTSW |
11 |
29,759,065 (GRCm38) |
missense |
probably benign |
0.13 |
|
R1687:Eml6
|
UTSW |
11 |
29,833,187 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1699:Eml6
|
UTSW |
11 |
29,746,282 (GRCm38) |
nonsense |
probably null |
|
|
R1796:Eml6
|
UTSW |
11 |
29,881,975 (GRCm38) |
missense |
probably benign |
0.19 |
|
R1797:Eml6
|
UTSW |
11 |
29,882,041 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1837:Eml6
|
UTSW |
11 |
29,749,802 (GRCm38) |
splice site |
probably null |
|
|
R1874:Eml6
|
UTSW |
11 |
29,831,136 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1967:Eml6
|
UTSW |
11 |
30,024,545 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1969:Eml6
|
UTSW |
11 |
29,833,075 (GRCm38) |
missense |
probably benign |
|
|
R2007:Eml6
|
UTSW |
11 |
29,848,814 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2012:Eml6
|
UTSW |
11 |
29,831,128 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R2198:Eml6
|
UTSW |
11 |
29,850,935 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2217:Eml6
|
UTSW |
11 |
29,818,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2218:Eml6
|
UTSW |
11 |
29,818,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2403:Eml6
|
UTSW |
11 |
29,802,434 (GRCm38) |
missense |
probably benign |
0.05 |
|
R2520:Eml6
|
UTSW |
11 |
29,791,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2937:Eml6
|
UTSW |
11 |
29,833,049 (GRCm38) |
splice site |
probably benign |
|
|
R2938:Eml6
|
UTSW |
11 |
29,833,049 (GRCm38) |
splice site |
probably benign |
|
|
R3085:Eml6
|
UTSW |
11 |
29,809,332 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3236:Eml6
|
UTSW |
11 |
29,831,097 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3738:Eml6
|
UTSW |
11 |
29,803,137 (GRCm38) |
missense |
probably benign |
0.20 |
|
R3739:Eml6
|
UTSW |
11 |
29,803,137 (GRCm38) |
missense |
probably benign |
0.20 |
|
R3752:Eml6
|
UTSW |
11 |
29,809,360 (GRCm38) |
missense |
probably benign |
0.06 |
|
R3854:Eml6
|
UTSW |
11 |
29,749,905 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R3941:Eml6
|
UTSW |
11 |
29,803,167 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4034:Eml6
|
UTSW |
11 |
29,803,137 (GRCm38) |
missense |
probably benign |
0.20 |
|
R4049:Eml6
|
UTSW |
11 |
29,838,577 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4108:Eml6
|
UTSW |
11 |
29,805,136 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4657:Eml6
|
UTSW |
11 |
29,805,108 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4662:Eml6
|
UTSW |
11 |
29,777,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4665:Eml6
|
UTSW |
11 |
29,819,007 (GRCm38) |
nonsense |
probably null |
|
|
R4721:Eml6
|
UTSW |
11 |
29,838,525 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R4729:Eml6
|
UTSW |
11 |
29,833,204 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4766:Eml6
|
UTSW |
11 |
29,805,757 (GRCm38) |
missense |
probably benign |
0.22 |
|
R4810:Eml6
|
UTSW |
11 |
29,755,011 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4831:Eml6
|
UTSW |
11 |
29,777,052 (GRCm38) |
nonsense |
probably null |
|
|
R5035:Eml6
|
UTSW |
11 |
29,854,187 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5064:Eml6
|
UTSW |
11 |
29,749,300 (GRCm38) |
missense |
probably benign |
0.12 |
|
R5103:Eml6
|
UTSW |
11 |
29,850,905 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5121:Eml6
|
UTSW |
11 |
29,744,606 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5161:Eml6
|
UTSW |
11 |
30,024,467 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5211:Eml6
|
UTSW |
11 |
29,854,145 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5268:Eml6
|
UTSW |
11 |
29,803,108 (GRCm38) |
missense |
probably benign |
0.15 |
|
R5390:Eml6
|
UTSW |
11 |
29,760,096 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5529:Eml6
|
UTSW |
11 |
29,764,126 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6239:Eml6
|
UTSW |
11 |
29,749,275 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6326:Eml6
|
UTSW |
11 |
29,819,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6395:Eml6
|
UTSW |
11 |
29,809,321 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6476:Eml6
|
UTSW |
11 |
29,791,971 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6483:Eml6
|
UTSW |
11 |
29,749,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6701:Eml6
|
UTSW |
11 |
29,785,748 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6753:Eml6
|
UTSW |
11 |
29,754,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6809:Eml6
|
UTSW |
11 |
29,803,161 (GRCm38) |
missense |
probably benign |
0.23 |
|
R6847:Eml6
|
UTSW |
11 |
29,818,447 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6855:Eml6
|
UTSW |
11 |
29,751,381 (GRCm38) |
splice site |
probably null |
|
|
R7168:Eml6
|
UTSW |
11 |
29,838,529 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7175:Eml6
|
UTSW |
11 |
29,784,231 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7305:Eml6
|
UTSW |
11 |
29,777,258 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7615:Eml6
|
UTSW |
11 |
29,802,501 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R7692:Eml6
|
UTSW |
11 |
29,753,085 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7980:Eml6
|
UTSW |
11 |
29,833,205 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8026:Eml6
|
UTSW |
11 |
29,749,973 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R8046:Eml6
|
UTSW |
11 |
29,758,981 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8049:Eml6
|
UTSW |
11 |
29,893,201 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8114:Eml6
|
UTSW |
11 |
29,754,910 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8425:Eml6
|
UTSW |
11 |
29,755,008 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8799:Eml6
|
UTSW |
11 |
29,758,981 (GRCm38) |
missense |
probably benign |
0.11 |
|
R8945:Eml6
|
UTSW |
11 |
29,753,110 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8977:Eml6
|
UTSW |
11 |
29,784,182 (GRCm38) |
missense |
possibly damaging |
0.59 |
|
R8986:Eml6
|
UTSW |
11 |
29,805,181 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R9088:Eml6
|
UTSW |
11 |
29,818,424 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9150:Eml6
|
UTSW |
11 |
29,805,791 (GRCm38) |
missense |
probably benign |
0.15 |
|
R9209:Eml6
|
UTSW |
11 |
29,831,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9288:Eml6
|
UTSW |
11 |
29,838,641 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R9467:Eml6
|
UTSW |
11 |
29,819,076 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9481:Eml6
|
UTSW |
11 |
29,838,641 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R9534:Eml6
|
UTSW |
11 |
29,784,155 (GRCm38) |
missense |
possibly damaging |
0.45 |
|
RF037:Eml6
|
UTSW |
11 |
29,752,549 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
RF039:Eml6
|
UTSW |
11 |
29,752,551 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCCACATTCTCTTGGTGAGGTGTTC -3'
(R):5'- GATGACATTCTCAGCCTGACCATCC -3'
Sequencing Primer
(F):5'- GTGTTCACATGTGGCTTCCA -3'
(R):5'- gccagaccaggttatttccag -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation