Mutagenetix > Incidental Mutation

Incidental Mutation 'R1496:Ptprz1'

168859

Institutional Source

Beutler Lab

Gene Symbol

Ptprz1

Ensembl Gene

ENSMUSG00000068748

Gene Name

protein tyrosine phosphatase receptor type Z, polypeptide 1

Synonyms

DSD-1-PG, phosphacan, Ptprz, Ptpz, PTPzeta, Rptpbeta, RPTPz, PTPbeta

MMRRC Submission

039547-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.715) question?

Stock #

R1496 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

22875501-23052915 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 23049523 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000143902 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090568] [ENSMUST00000202102]

AlphaFold

B9EKR1

Predicted Effect

probably benign
Transcript: ENSMUST00000090568

SMART Domains

Protein: ENSMUSP00000088056
Gene: ENSMUSG00000068748

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
low complexity region	825	837	N/A	INTRINSIC
low complexity region	1417	1441	N/A	INTRINSIC
low complexity region	1485	1495	N/A	INTRINSIC
Blast:PTPc	1497	1573	1e-12	BLAST
low complexity region	1606	1620	N/A	INTRINSIC
transmembrane domain	1637	1659	N/A	INTRINSIC
low complexity region	1679	1693	N/A	INTRINSIC
PTPc	1720	1991	2.8e-130	SMART
PTPc	2019	2281	1.65e-77	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000200769

Predicted Effect

probably benign
Transcript: ENSMUST00000202102

SMART Domains

Protein: ENSMUSP00000143902
Gene: ENSMUSG00000068748

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
Carb_anhydrase	38	300	5.12e-99	SMART
FN3	312	397	5.53e-4	SMART
low complexity region	588	609	N/A	INTRINSIC
transmembrane domain	788	810	N/A	INTRINSIC
low complexity region	830	844	N/A	INTRINSIC
PTPc	871	1142	2.8e-130	SMART
PTPc	1170	1432	1.65e-77	SMART

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.3%
20x: 92.9%

Validation Efficiency

98% (94/96)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
PHENOTYPE: Mice homozygous for targeted null mutations demonstrate an impaired ability to recover from inflamatory lesions of the CNS or gastric mucosa. Mice homozygous for a knock-out allele exhibit increased tactile and thermal nociception thresholds. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 90 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4931429L15Rik	A	G	9: 46,221,552 (GRCm39)		probably benign	Het
4933411K16Rik	T	C	19: 42,041,489 (GRCm39)	Y207H	probably damaging	Het
Abcc1	T	A	16: 14,266,298 (GRCm39)	L832Q	probably damaging	Het
Acan	T	A	7: 78,750,552 (GRCm39)	H1774Q	probably benign	Het
Adss2	T	C	1: 177,599,760 (GRCm39)	T275A	probably benign	Het
Ano5	G	A	7: 51,233,523 (GRCm39)	R595H	probably damaging	Het
Araf	G	T	X: 20,725,943 (GRCm39)	R522L	probably damaging	Het
Arhgef28	C	T	13: 98,102,054 (GRCm39)	V807I	possibly damaging	Het
Bin1	T	C	18: 32,545,757 (GRCm39)	I103T	probably damaging	Het
C4b	C	T	17: 34,958,995 (GRCm39)	R478Q	probably benign	Het
Cacna1b	G	A	2: 24,568,047 (GRCm39)	P1015S	probably benign	Het
Capn1	A	G	19: 6,057,528 (GRCm39)		probably null	Het
Cep290	A	G	10: 100,374,828 (GRCm39)	Q1358R	probably damaging	Het
Cfap126	T	C	1: 170,953,386 (GRCm39)		probably benign	Het
Chn1	T	C	2: 73,509,951 (GRCm39)		probably benign	Het
Cldn8	T	C	16: 88,359,289 (GRCm39)	E212G	probably benign	Het
Cpb1	T	C	3: 20,317,696 (GRCm39)	N249S	probably damaging	Het
Cxcr6	A	T	9: 123,639,412 (GRCm39)	I138F	probably benign	Het
Dab2ip	G	A	2: 35,608,803 (GRCm39)	R579H	probably damaging	Het
Dcaf8	T	C	1: 172,021,422 (GRCm39)	M538T	probably benign	Het
Dhrs4	T	G	14: 55,725,107 (GRCm39)	L201V	probably damaging	Het
Dnah12	C	T	14: 26,431,403 (GRCm39)	A407V	probably benign	Het
Elavl3	T	A	9: 21,937,461 (GRCm39)		probably benign	Het
Elp4	T	C	2: 105,662,506 (GRCm39)	H88R	probably benign	Het
Ercc3	T	C	18: 32,394,350 (GRCm39)		probably benign	Het
Eri1	A	G	8: 35,936,335 (GRCm39)	S329P	possibly damaging	Het
Erich2	A	T	2: 70,343,117 (GRCm39)		probably benign	Het
Esyt1	A	G	10: 128,348,297 (GRCm39)	S864P	possibly damaging	Het
Fam170b	A	G	14: 32,557,588 (GRCm39)	E141G	probably damaging	Het
Fat1	A	G	8: 45,486,427 (GRCm39)	Y3304C	probably damaging	Het
Fbn1	T	C	2: 125,151,415 (GRCm39)	T2531A	probably benign	Het
Fgfr3	T	C	5: 33,887,094 (GRCm39)	V166A	probably damaging	Het
Glt8d2	T	C	10: 82,495,372 (GRCm39)	D194G	probably damaging	Het
Gpr89	A	G	3: 96,812,526 (GRCm39)	I5T	probably benign	Het
Gpx6	A	T	13: 21,503,090 (GRCm39)	H168L	probably benign	Het
Gusb	T	C	5: 130,027,385 (GRCm39)	T307A	probably benign	Het
Hjurp	A	T	1: 88,202,772 (GRCm39)	Y71N	possibly damaging	Het
Ifngr1	A	G	10: 19,477,193 (GRCm39)	D118G	probably benign	Het
Ipcef1	A	T	10: 6,885,173 (GRCm39)		probably null	Het
Kbtbd3	A	T	9: 4,330,276 (GRCm39)	T217S	probably benign	Het
Kmt5a	GAA	GA	5: 124,597,948 (GRCm39)		probably null	Het
Lrp1	T	C	10: 127,374,880 (GRCm39)	D4526G	probably damaging	Het
Lrp1b	A	T	2: 42,213,674 (GRCm39)	V46D	probably damaging	Het
Lsm8	T	A	6: 18,849,658 (GRCm39)	M22K	probably benign	Het
Map1lc3b	C	T	8: 122,323,339 (GRCm39)	R70C	possibly damaging	Het
Meiob	T	A	17: 25,032,026 (GRCm39)	S14T	possibly damaging	Het
Mkx	G	T	18: 6,992,330 (GRCm39)	Y183*	probably null	Het
Mrs2	T	C	13: 25,189,017 (GRCm39)	Y99C	probably benign	Het
Mycbpap	T	C	11: 94,396,387 (GRCm39)	K151R	probably benign	Het
Neb	T	G	2: 52,218,746 (GRCm39)	Q88P	probably damaging	Het
Noc4l	T	A	5: 110,797,944 (GRCm39)	H319L	probably damaging	Het
Nt5c2	G	A	19: 46,893,417 (GRCm39)	T122I	probably damaging	Het
Nuggc	A	T	14: 65,861,582 (GRCm39)	N476I	probably damaging	Het
Obscn	T	A	11: 58,921,862 (GRCm39)	H5978L	probably benign	Het
Oc90	G	T	15: 65,748,370 (GRCm39)	A412D	probably damaging	Het
Or2l13b	T	A	16: 19,349,133 (GRCm39)	D179V	possibly damaging	Het
Or3a4	A	G	11: 73,944,650 (GRCm39)	*312Q	probably null	Het
Or4a76	A	G	2: 89,460,358 (GRCm39)	S295P	possibly damaging	Het
Or5w18	T	G	2: 87,633,212 (GRCm39)	S160A	probably benign	Het
Or7a42	T	A	10: 78,791,682 (GRCm39)	S214R	probably benign	Het
Or8k33	A	T	2: 86,384,096 (GRCm39)	V124E	probably damaging	Het
Pdzrn3	A	T	6: 101,127,930 (GRCm39)	V912E	probably benign	Het
Phactr1	T	A	13: 43,248,466 (GRCm39)	Y387N	probably damaging	Het
Picalm	T	A	7: 89,779,859 (GRCm39)	C27S	probably benign	Het
Pkd1l1	T	A	11: 8,891,077 (GRCm39)	I314F	possibly damaging	Het
Pold2	T	C	11: 5,824,175 (GRCm39)	E210G	possibly damaging	Het
Rac1	G	T	5: 143,493,093 (GRCm39)	A165E	probably damaging	Het
Rpap3	G	T	15: 97,584,364 (GRCm39)	T360K	possibly damaging	Het
Scn9a	G	A	2: 66,357,232 (GRCm39)	T1012I	probably benign	Het
Sdad1	A	G	5: 92,457,682 (GRCm39)	I20T	possibly damaging	Het
Setbp1	T	G	18: 78,903,127 (GRCm39)	K180T	probably damaging	Het
Sgpl1	T	C	10: 60,938,368 (GRCm39)	N475S	probably damaging	Het
Shroom3	T	C	5: 93,090,693 (GRCm39)	S1148P	possibly damaging	Het
Sin3a	T	A	9: 57,026,442 (GRCm39)	H1119Q	possibly damaging	Het
Slc26a7	T	A	4: 14,506,489 (GRCm39)	Y620F	probably benign	Het
Slc4a1	T	C	11: 102,251,997 (GRCm39)	I36V	probably benign	Het
Smarca2	C	G	19: 26,608,501 (GRCm39)	P263A	possibly damaging	Het
Sp100	T	C	1: 85,591,242 (GRCm39)		probably benign	Het
Spag6l	A	G	16: 16,598,478 (GRCm39)		probably benign	Het
Sptbn1	T	C	11: 30,071,498 (GRCm39)	N1491S	probably damaging	Het
Tbl1xr1	T	G	3: 22,245,115 (GRCm39)	V155G	possibly damaging	Het
Tmc1	A	G	19: 20,845,719 (GRCm39)	I168T	probably damaging	Het
Tmem87b	G	A	2: 128,668,313 (GRCm39)		probably null	Het
Tnfrsf9	T	A	4: 151,017,561 (GRCm39)		probably null	Het
Tnni3k	T	C	3: 154,645,295 (GRCm39)	D530G	probably damaging	Het
Vmn1r209	G	A	13: 22,989,934 (GRCm39)	S252F	probably damaging	Het
Zbtb3	A	T	19: 8,780,714 (GRCm39)	N109I	probably damaging	Het
Zdhhc17	T	G	10: 110,782,071 (GRCm39)	H541P	probably damaging	Het
Zfp84	A	G	7: 29,476,039 (GRCm39)	I244V	possibly damaging	Het
Zyx	A	G	6: 42,333,246 (GRCm39)	Y393C	probably damaging	Het

Other mutations in Ptprz1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00486:Ptprz1	APN	6	22,973,053 (GRCm39)	missense	probably damaging	1.00
IGL00773:Ptprz1	APN	6	23,002,628 (GRCm39)	missense	probably benign	0.41
IGL01458:Ptprz1	APN	6	22,972,843 (GRCm39)	missense	probably damaging	0.99
IGL01481:Ptprz1	APN	6	22,999,979 (GRCm39)	missense	probably benign	0.05
IGL01501:Ptprz1	APN	6	22,973,081 (GRCm39)	missense	probably damaging	1.00
IGL01601:Ptprz1	APN	6	23,000,437 (GRCm39)	missense	probably damaging	0.99
IGL01882:Ptprz1	APN	6	23,000,463 (GRCm39)	missense	probably damaging	1.00
IGL02058:Ptprz1	APN	6	23,002,502 (GRCm39)	missense	probably benign	0.00
IGL02089:Ptprz1	APN	6	23,033,447 (GRCm39)	missense	probably damaging	1.00
IGL02136:Ptprz1	APN	6	22,972,821 (GRCm39)	missense	probably damaging	1.00
IGL02215:Ptprz1	APN	6	22,965,181 (GRCm39)	missense	possibly damaging	0.91
IGL02220:Ptprz1	APN	6	23,042,742 (GRCm39)	splice site	probably benign
IGL02556:Ptprz1	APN	6	22,972,844 (GRCm39)	missense	probably benign	0.01
IGL02601:Ptprz1	APN	6	23,000,686 (GRCm39)	missense	probably benign	0.11
IGL02620:Ptprz1	APN	6	22,959,739 (GRCm39)	missense	probably damaging	1.00
IGL02666:Ptprz1	APN	6	23,001,209 (GRCm39)	missense	probably benign	0.00
IGL02718:Ptprz1	APN	6	23,001,348 (GRCm39)	missense	possibly damaging	0.77
IGL02792:Ptprz1	APN	6	22,959,722 (GRCm39)	missense	probably damaging	1.00
IGL02894:Ptprz1	APN	6	23,035,148 (GRCm39)	missense	probably damaging	1.00
IGL02952:Ptprz1	APN	6	23,036,925 (GRCm39)	missense	probably damaging	1.00
IGL03003:Ptprz1	APN	6	23,002,582 (GRCm39)	missense	probably damaging	0.98
IGL03060:Ptprz1	APN	6	22,972,834 (GRCm39)	missense	probably damaging	1.00
IGL03170:Ptprz1	APN	6	22,959,766 (GRCm39)	missense	probably benign	0.00
IGL03246:Ptprz1	APN	6	22,986,159 (GRCm39)	missense	probably damaging	0.99
IGL03349:Ptprz1	APN	6	23,000,331 (GRCm39)	missense	probably damaging	1.00
IGL03365:Ptprz1	APN	6	23,030,581 (GRCm39)	splice site	probably benign
Elevator	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
escalator	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R0044:Ptprz1	UTSW	6	23,007,402 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0054:Ptprz1	UTSW	6	22,986,195 (GRCm39)	missense	probably damaging	1.00
R0107:Ptprz1	UTSW	6	23,000,569 (GRCm39)	missense	probably damaging	0.98
R0278:Ptprz1	UTSW	6	23,000,816 (GRCm39)	missense	probably benign	0.31
R0345:Ptprz1	UTSW	6	23,016,164 (GRCm39)	missense	probably damaging	1.00
R0359:Ptprz1	UTSW	6	22,973,175 (GRCm39)	splice site	probably benign
R0743:Ptprz1	UTSW	6	23,044,366 (GRCm39)	nonsense	probably null
R1014:Ptprz1	UTSW	6	23,000,643 (GRCm39)	missense	probably damaging	1.00
R1016:Ptprz1	UTSW	6	23,000,973 (GRCm39)	missense	probably damaging	1.00
R1106:Ptprz1	UTSW	6	22,965,748 (GRCm39)	missense	probably damaging	0.99
R1391:Ptprz1	UTSW	6	23,001,728 (GRCm39)	missense	probably benign	0.33
R1424:Ptprz1	UTSW	6	23,000,382 (GRCm39)	missense	probably benign	0.00
R1445:Ptprz1	UTSW	6	23,050,473 (GRCm39)	missense	probably damaging	1.00
R1544:Ptprz1	UTSW	6	23,000,747 (GRCm39)	missense	possibly damaging	0.63
R1626:Ptprz1	UTSW	6	23,001,573 (GRCm39)	missense	probably benign
R1641:Ptprz1	UTSW	6	23,049,605 (GRCm39)	missense	probably damaging	1.00
R1757:Ptprz1	UTSW	6	23,044,319 (GRCm39)	missense	probably damaging	1.00
R1812:Ptprz1	UTSW	6	22,959,711 (GRCm39)	missense	probably benign	0.07
R1917:Ptprz1	UTSW	6	23,035,039 (GRCm39)	splice site	probably benign
R1930:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1931:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R1974:Ptprz1	UTSW	6	22,986,310 (GRCm39)	missense	probably damaging	1.00
R1992:Ptprz1	UTSW	6	22,959,747 (GRCm39)	missense	probably benign	0.24
R1997:Ptprz1	UTSW	6	23,050,496 (GRCm39)	missense	probably damaging	0.99
R2002:Ptprz1	UTSW	6	23,027,833 (GRCm39)	nonsense	probably null
R2012:Ptprz1	UTSW	6	23,001,026 (GRCm39)	missense	probably benign	0.03
R2059:Ptprz1	UTSW	6	22,986,322 (GRCm39)	splice site	probably benign
R2061:Ptprz1	UTSW	6	23,049,674 (GRCm39)	critical splice donor site	probably null
R2064:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2067:Ptprz1	UTSW	6	23,050,388 (GRCm39)	splice site	probably benign
R2108:Ptprz1	UTSW	6	23,033,476 (GRCm39)	missense	probably damaging	0.99
R2152:Ptprz1	UTSW	6	23,030,670 (GRCm39)	missense	probably damaging	0.99
R2166:Ptprz1	UTSW	6	23,045,632 (GRCm39)	missense	possibly damaging	0.90
R2183:Ptprz1	UTSW	6	23,002,284 (GRCm39)	missense	probably benign
R2202:Ptprz1	UTSW	6	23,000,649 (GRCm39)	missense	possibly damaging	0.63
R2238:Ptprz1	UTSW	6	22,987,376 (GRCm39)	missense	probably damaging	1.00
R2290:Ptprz1	UTSW	6	23,000,990 (GRCm39)	missense	probably damaging	1.00
R3027:Ptprz1	UTSW	6	23,016,196 (GRCm39)	missense	possibly damaging	0.89
R3861:Ptprz1	UTSW	6	23,036,894 (GRCm39)	missense	probably damaging	0.98
R4012:Ptprz1	UTSW	6	23,002,584 (GRCm39)	missense	probably damaging	0.99
R4020:Ptprz1	UTSW	6	22,959,623 (GRCm39)	splice site	probably benign
R4158:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4158:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4159:Ptprz1	UTSW	6	23,001,683 (GRCm39)	nonsense	probably null
R4160:Ptprz1	UTSW	6	23,022,204 (GRCm39)	missense	possibly damaging	0.73
R4606:Ptprz1	UTSW	6	23,001,486 (GRCm39)	missense	possibly damaging	0.80
R4621:Ptprz1	UTSW	6	23,001,453 (GRCm39)	missense	possibly damaging	0.68
R4640:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	1.00
R4731:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4732:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4733:Ptprz1	UTSW	6	23,002,609 (GRCm39)	missense	probably benign	0.06
R4803:Ptprz1	UTSW	6	23,001,545 (GRCm39)	missense	probably benign	0.00
R4890:Ptprz1	UTSW	6	23,024,957 (GRCm39)	missense	probably damaging	1.00
R5035:Ptprz1	UTSW	6	23,016,214 (GRCm39)	missense	probably benign	0.06
R5052:Ptprz1	UTSW	6	23,045,625 (GRCm39)	missense	probably damaging	1.00
R5106:Ptprz1	UTSW	6	23,000,027 (GRCm39)	missense	probably benign	0.04
R5248:Ptprz1	UTSW	6	23,001,900 (GRCm39)	missense	probably benign	0.11
R5292:Ptprz1	UTSW	6	23,002,581 (GRCm39)	missense	probably benign	0.31
R5373:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5374:Ptprz1	UTSW	6	23,007,354 (GRCm39)	missense	probably damaging	1.00
R5378:Ptprz1	UTSW	6	23,007,401 (GRCm39)	missense	probably damaging	1.00
R5408:Ptprz1	UTSW	6	23,002,599 (GRCm39)	missense	probably damaging	1.00
R5479:Ptprz1	UTSW	6	23,001,665 (GRCm39)	missense	probably benign
R5524:Ptprz1	UTSW	6	22,986,317 (GRCm39)	splice site	probably null
R5527:Ptprz1	UTSW	6	23,000,052 (GRCm39)	missense	possibly damaging	0.66
R5557:Ptprz1	UTSW	6	23,001,000 (GRCm39)	missense	probably benign	0.04
R5654:Ptprz1	UTSW	6	22,986,133 (GRCm39)	missense	probably damaging	1.00
R5655:Ptprz1	UTSW	6	22,999,772 (GRCm39)	missense	probably benign	0.00
R5658:Ptprz1	UTSW	6	23,016,188 (GRCm39)	missense	probably damaging	1.00
R5663:Ptprz1	UTSW	6	23,035,142 (GRCm39)	missense	probably damaging	1.00
R5765:Ptprz1	UTSW	6	23,000,235 (GRCm39)	missense	probably damaging	1.00
R5822:Ptprz1	UTSW	6	23,001,444 (GRCm39)	missense	probably benign	0.01
R5837:Ptprz1	UTSW	6	23,001,417 (GRCm39)	missense	probably benign	0.00
R6108:Ptprz1	UTSW	6	23,045,658 (GRCm39)	missense	probably damaging	1.00
R6199:Ptprz1	UTSW	6	23,002,470 (GRCm39)	missense	probably benign	0.01
R6245:Ptprz1	UTSW	6	23,051,989 (GRCm39)	missense	probably damaging	1.00
R6257:Ptprz1	UTSW	6	22,959,639 (GRCm39)	missense	probably damaging	1.00
R6488:Ptprz1	UTSW	6	23,001,516 (GRCm39)	nonsense	probably null
R6606:Ptprz1	UTSW	6	23,002,500 (GRCm39)	missense	probably benign	0.27
R6612:Ptprz1	UTSW	6	23,052,081 (GRCm39)	missense	probably damaging	1.00
R6824:Ptprz1	UTSW	6	23,002,130 (GRCm39)	missense	probably benign	0.05
R6834:Ptprz1	UTSW	6	22,999,632 (GRCm39)	missense	probably benign	0.38
R6836:Ptprz1	UTSW	6	23,030,664 (GRCm39)	nonsense	probably null
R6991:Ptprz1	UTSW	6	23,002,686 (GRCm39)	missense	probably benign	0.00
R7044:Ptprz1	UTSW	6	23,044,345 (GRCm39)	missense	probably damaging	1.00
R7048:Ptprz1	UTSW	6	22,961,622 (GRCm39)	missense	probably benign	0.18
R7225:Ptprz1	UTSW	6	23,000,928 (GRCm39)	missense	possibly damaging	0.61
R7284:Ptprz1	UTSW	6	23,000,097 (GRCm39)	missense	probably damaging	1.00
R7360:Ptprz1	UTSW	6	23,000,906 (GRCm39)	missense	probably damaging	1.00
R7501:Ptprz1	UTSW	6	23,001,746 (GRCm39)	nonsense	probably null
R7515:Ptprz1	UTSW	6	23,022,266 (GRCm39)	missense	probably damaging	1.00
R7538:Ptprz1	UTSW	6	22,999,895 (GRCm39)	missense	possibly damaging	0.81
R7567:Ptprz1	UTSW	6	22,959,779 (GRCm39)	missense	probably damaging	0.97
R7599:Ptprz1	UTSW	6	23,002,518 (GRCm39)	missense	not run
R7611:Ptprz1	UTSW	6	23,001,219 (GRCm39)	missense	probably benign
R7685:Ptprz1	UTSW	6	23,024,977 (GRCm39)	missense	probably damaging	1.00
R7707:Ptprz1	UTSW	6	23,002,295 (GRCm39)	missense	probably benign	0.00
R7733:Ptprz1	UTSW	6	23,000,383 (GRCm39)	missense	probably benign	0.31
R7786:Ptprz1	UTSW	6	23,036,992 (GRCm39)	missense	probably damaging	1.00
R7868:Ptprz1	UTSW	6	23,000,963 (GRCm39)	missense	not run
R7882:Ptprz1	UTSW	6	23,002,256 (GRCm39)	missense	probably benign	0.13
R7968:Ptprz1	UTSW	6	22,959,675 (GRCm39)	missense	probably damaging	0.98
R8024:Ptprz1	UTSW	6	23,042,750 (GRCm39)	missense	probably damaging	1.00
R8157:Ptprz1	UTSW	6	23,002,539 (GRCm39)	missense	probably damaging	1.00
R8159:Ptprz1	UTSW	6	23,001,662 (GRCm39)	missense	probably benign
R8354:Ptprz1	UTSW	6	22,999,614 (GRCm39)	missense	probably damaging	0.99
R8496:Ptprz1	UTSW	6	22,972,797 (GRCm39)	missense	probably damaging	0.96
R8757:Ptprz1	UTSW	6	22,972,716 (GRCm39)	missense	possibly damaging	0.74
R8767:Ptprz1	UTSW	6	22,986,187 (GRCm39)	missense	probably damaging	1.00
R8783:Ptprz1	UTSW	6	23,002,026 (GRCm39)	missense	probably benign	0.00
R8811:Ptprz1	UTSW	6	23,030,661 (GRCm39)	missense	probably benign	0.03
R8817:Ptprz1	UTSW	6	23,007,371 (GRCm39)	missense	probably damaging	1.00
R8822:Ptprz1	UTSW	6	23,002,588 (GRCm39)	missense	probably damaging	0.98
R8874:Ptprz1	UTSW	6	23,042,747 (GRCm39)	missense
R9009:Ptprz1	UTSW	6	23,001,653 (GRCm39)	missense	possibly damaging	0.94
R9126:Ptprz1	UTSW	6	23,002,334 (GRCm39)	nonsense	probably null
R9201:Ptprz1	UTSW	6	22,972,869 (GRCm39)	critical splice donor site	probably null
R9210:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9212:Ptprz1	UTSW	6	23,050,493 (GRCm39)	missense	probably damaging	0.99
R9229:Ptprz1	UTSW	6	22,986,283 (GRCm39)	missense	probably null	0.03
R9279:Ptprz1	UTSW	6	23,002,444 (GRCm39)	missense	probably benign
R9336:Ptprz1	UTSW	6	23,000,855 (GRCm39)	missense	probably benign	0.01
R9372:Ptprz1	UTSW	6	23,045,706 (GRCm39)	missense	probably damaging	1.00
R9577:Ptprz1	UTSW	6	23,002,202 (GRCm39)	missense	probably damaging	1.00
R9594:Ptprz1	UTSW	6	23,025,026 (GRCm39)	missense	probably damaging	0.98
R9632:Ptprz1	UTSW	6	23,007,292 (GRCm39)	missense	probably damaging	1.00
R9636:Ptprz1	UTSW	6	22,999,994 (GRCm39)	missense	probably benign
R9657:Ptprz1	UTSW	6	23,042,377 (GRCm39)	missense	possibly damaging	0.92
R9694:Ptprz1	UTSW	6	22,959,694 (GRCm39)	missense	probably damaging	1.00
R9716:Ptprz1	UTSW	6	22,959,650 (GRCm39)	missense	probably damaging	1.00
R9794:Ptprz1	UTSW	6	23,000,204 (GRCm39)	missense	probably benign	0.00
Z1176:Ptprz1	UTSW	6	23,051,994 (GRCm39)	missense	probably damaging	0.99
Z1177:Ptprz1	UTSW	6	23,052,023 (GRCm39)	missense	probably damaging	1.00
Z1177:Ptprz1	UTSW	6	22,999,839 (GRCm39)	missense	possibly damaging	0.51

Predicted Primers

PCR Primer
(F):5'- TCTCCTTCCAGGATGAGGGATGAAC -3'
(R):5'- GACACAGGTATTCTGCCTTCACCAG -3'

Sequencing Primer
(F):5'- TGAGGGATGAACTACAAATAAAGC -3'
(R):5'- TCCTTGCTGAATCAACACATGG -3'

Posted On

2014-04-13