Incidental Mutation 'R1498:Ppl'
| ID |
169078 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ppl
|
| Ensembl Gene |
ENSMUSG00000039457 |
| Gene Name |
periplakin |
| Synonyms |
|
| MMRRC Submission |
039549-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1498 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
4904155-4950285 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 4922629 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 260
(N260S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039360
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035672]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000035672
AA Change: N260S
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000039360
Gene: ENSMUSG00000039457
AA Change: N260S
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
123 |
211 |
1.58e0 |
SMART |
|
SPEC
|
214 |
315 |
3.38e-2 |
SMART |
|
SPEC
|
321 |
483 |
1.11e-2 |
SMART |
|
SPEC
|
503 |
610 |
4.96e0 |
SMART |
|
Blast:SPEC
|
613 |
717 |
5e-59 |
BLAST |
|
low complexity region
|
718 |
729 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
732 |
859 |
2e-60 |
BLAST |
|
low complexity region
|
893 |
908 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
984 |
1004 |
3.46e-5 |
PROSPERO |
|
internal_repeat_1
|
992 |
1008 |
8.09e-7 |
PROSPERO |
|
low complexity region
|
1011 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1027 |
1042 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1112 |
1128 |
8.09e-7 |
PROSPERO |
|
coiled coil region
|
1180 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1355 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1433 |
N/A |
INTRINSIC |
|
low complexity region
|
1455 |
1479 |
N/A |
INTRINSIC |
|
Blast:SPEC
|
1529 |
1610 |
8e-30 |
BLAST |
|
low complexity region
|
1612 |
1630 |
N/A |
INTRINSIC |
|
PLEC
|
1649 |
1683 |
1.34e-5 |
SMART |
|
PLEC
|
1698 |
1733 |
2.23e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000230554
|
| Meta Mutation Damage Score |
0.0590 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.6%
|
| Validation Efficiency |
97% (83/86) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice are fertile and grossly normal with no apparent skin abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(1) : Targeted, knock-out(1) |
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acly |
A |
G |
11: 100,374,627 (GRCm39) |
S799P |
probably benign |
Het |
| Acvr1b |
T |
C |
15: 101,091,891 (GRCm39) |
F57S |
probably benign |
Het |
| Adamts5 |
T |
A |
16: 85,696,990 (GRCm39) |
T56S |
possibly damaging |
Het |
| Adrb2 |
T |
C |
18: 62,312,004 (GRCm39) |
T274A |
probably damaging |
Het |
| Agr3 |
A |
T |
12: 35,984,379 (GRCm39) |
|
probably null |
Het |
| Ankrd6 |
A |
G |
4: 32,810,289 (GRCm39) |
M405T |
probably benign |
Het |
| Aoc1l2 |
A |
G |
6: 48,908,305 (GRCm39) |
H435R |
probably benign |
Het |
| Aqp5 |
T |
C |
15: 99,491,128 (GRCm39) |
I60T |
probably damaging |
Het |
| Arf5 |
G |
T |
6: 28,426,153 (GRCm39) |
R180L |
probably benign |
Het |
| Asap3 |
A |
G |
4: 135,966,505 (GRCm39) |
N528D |
probably benign |
Het |
| Atmin |
G |
A |
8: 117,681,540 (GRCm39) |
E180K |
probably benign |
Het |
| Bcl11a |
A |
T |
11: 24,114,005 (GRCm39) |
E449D |
probably damaging |
Het |
| Cep128 |
A |
T |
12: 91,333,191 (GRCm39) |
F25I |
probably benign |
Het |
| Cfp |
GCAC |
GC |
X: 20,795,905 (GRCm39) |
|
probably null |
Het |
| Chpt1 |
T |
A |
10: 88,312,966 (GRCm39) |
Y282F |
possibly damaging |
Het |
| Cul7 |
A |
G |
17: 46,966,636 (GRCm39) |
D355G |
probably benign |
Het |
| Daxx |
T |
C |
17: 34,131,227 (GRCm39) |
Y385H |
probably damaging |
Het |
| Dnah2 |
A |
C |
11: 69,411,493 (GRCm39) |
|
probably null |
Het |
| Dscc1 |
CTGAATGAAT |
CTGAAT |
15: 54,943,572 (GRCm39) |
|
probably benign |
Het |
| Erc2 |
T |
A |
14: 28,024,855 (GRCm39) |
M578K |
probably benign |
Het |
| Evc |
T |
A |
5: 37,481,044 (GRCm39) |
H267L |
possibly damaging |
Het |
| Exosc10 |
A |
C |
4: 148,666,243 (GRCm39) |
Q837P |
possibly damaging |
Het |
| Fasn |
G |
A |
11: 120,706,245 (GRCm39) |
T1033I |
probably damaging |
Het |
| Fat1 |
C |
A |
8: 45,478,521 (GRCm39) |
Y2522* |
probably null |
Het |
| Fbxw8 |
G |
A |
5: 118,203,850 (GRCm39) |
|
probably benign |
Het |
| Fyn |
A |
G |
10: 39,408,120 (GRCm39) |
D321G |
possibly damaging |
Het |
| Grm6 |
G |
A |
11: 50,748,083 (GRCm39) |
V398M |
probably damaging |
Het |
| Gtpbp1 |
T |
A |
15: 79,603,222 (GRCm39) |
|
probably null |
Het |
| Hnf1a |
A |
G |
5: 115,108,596 (GRCm39) |
V103A |
probably damaging |
Het |
| Hsp90aa1 |
A |
T |
12: 110,662,122 (GRCm39) |
|
probably null |
Het |
| Iqgap2 |
C |
T |
13: 95,783,313 (GRCm39) |
V1288I |
probably benign |
Het |
| Irx5 |
A |
G |
8: 93,086,514 (GRCm39) |
D199G |
probably damaging |
Het |
| Klrh1 |
A |
G |
6: 129,748,703 (GRCm39) |
S105P |
probably damaging |
Het |
| Krt9 |
G |
T |
11: 100,079,195 (GRCm39) |
C732* |
probably null |
Het |
| Lifr |
T |
C |
15: 7,220,099 (GRCm39) |
S910P |
probably damaging |
Het |
| Lrig1 |
G |
A |
6: 94,604,968 (GRCm39) |
A209V |
possibly damaging |
Het |
| Lrrk1 |
T |
A |
7: 65,952,419 (GRCm39) |
R506* |
probably null |
Het |
| Lyst |
T |
A |
13: 13,824,960 (GRCm39) |
I1525K |
possibly damaging |
Het |
| Mad2l1 |
C |
T |
6: 66,516,826 (GRCm39) |
Q173* |
probably null |
Het |
| Mcoln1 |
T |
A |
8: 3,562,861 (GRCm39) |
I524N |
probably damaging |
Het |
| Mmp3 |
A |
T |
9: 7,446,967 (GRCm39) |
D49V |
possibly damaging |
Het |
| Morc3 |
A |
T |
16: 93,650,743 (GRCm39) |
N321I |
probably damaging |
Het |
| Mrpl48 |
T |
C |
7: 100,195,695 (GRCm39) |
|
probably benign |
Het |
| Myo6 |
T |
A |
9: 80,214,961 (GRCm39) |
D1231E |
probably damaging |
Het |
| Nlrc4 |
A |
G |
17: 74,753,408 (GRCm39) |
I325T |
probably benign |
Het |
| Or1j19 |
A |
T |
2: 36,677,358 (GRCm39) |
I274F |
probably damaging |
Het |
| Or2ag17 |
T |
C |
7: 106,389,623 (GRCm39) |
Y195C |
possibly damaging |
Het |
| Or4f61 |
A |
T |
2: 111,922,938 (GRCm39) |
M36K |
probably benign |
Het |
| Or8c16 |
C |
G |
9: 38,130,676 (GRCm39) |
P183A |
probably damaging |
Het |
| Or8k32 |
A |
G |
2: 86,368,902 (GRCm39) |
V117A |
probably benign |
Het |
| Parvg |
T |
A |
15: 84,218,832 (GRCm39) |
S230T |
possibly damaging |
Het |
| Pcca |
T |
C |
14: 122,854,230 (GRCm39) |
I118T |
probably damaging |
Het |
| Pde6a |
A |
G |
18: 61,365,932 (GRCm39) |
N219S |
possibly damaging |
Het |
| Phldb1 |
G |
T |
9: 44,612,915 (GRCm39) |
P935Q |
possibly damaging |
Het |
| Plppr5 |
T |
C |
3: 117,456,261 (GRCm39) |
S261P |
probably damaging |
Het |
| Ppp1r3e |
A |
T |
14: 55,113,882 (GRCm39) |
H263Q |
probably benign |
Het |
| Ppp3cb |
T |
C |
14: 20,559,567 (GRCm39) |
|
probably null |
Het |
| Ppt2 |
A |
T |
17: 34,842,075 (GRCm39) |
D185E |
probably benign |
Het |
| Prr27 |
A |
T |
5: 87,998,600 (GRCm39) |
|
probably benign |
Het |
| Ptcd3 |
A |
T |
6: 71,870,479 (GRCm39) |
V327E |
probably damaging |
Het |
| Pwwp4a |
G |
T |
X: 72,171,261 (GRCm39) |
G218C |
probably damaging |
Het |
| Rsf1 |
GCG |
GCGACG |
7: 97,229,114 (GRCm39) |
|
probably benign |
Het |
| Rtp1 |
A |
T |
16: 23,249,970 (GRCm39) |
M112L |
probably benign |
Het |
| Slc22a5 |
A |
T |
11: 53,760,140 (GRCm39) |
L392Q |
probably damaging |
Het |
| Slc6a7 |
A |
G |
18: 61,129,764 (GRCm39) |
I614T |
probably benign |
Het |
| Slu7 |
C |
A |
11: 43,329,044 (GRCm39) |
P89T |
possibly damaging |
Het |
| Smarcc2 |
T |
C |
10: 128,318,061 (GRCm39) |
V618A |
probably benign |
Het |
| Sorl1 |
C |
T |
9: 41,952,369 (GRCm39) |
R729Q |
probably damaging |
Het |
| Sptbn2 |
T |
C |
19: 4,794,274 (GRCm39) |
F1493L |
possibly damaging |
Het |
| Sulf1 |
C |
T |
1: 12,918,574 (GRCm39) |
T66I |
probably damaging |
Het |
| Tgtp2 |
A |
G |
11: 48,950,165 (GRCm39) |
Y136H |
probably damaging |
Het |
| Tmem117 |
T |
C |
15: 94,536,242 (GRCm39) |
F92S |
probably damaging |
Het |
| Tmprss9 |
T |
A |
10: 80,730,934 (GRCm39) |
V820E |
probably benign |
Het |
| Tpcn2 |
A |
G |
7: 144,822,648 (GRCm39) |
Y266H |
probably damaging |
Het |
| Trat1 |
A |
G |
16: 48,555,304 (GRCm39) |
S143P |
probably benign |
Het |
| Vmn1r49 |
T |
A |
6: 90,049,298 (GRCm39) |
R235W |
probably damaging |
Het |
| Vmn1r71 |
A |
T |
7: 10,482,575 (GRCm39) |
C38S |
probably benign |
Het |
| Vmn2r6 |
T |
A |
3: 64,463,890 (GRCm39) |
T315S |
probably damaging |
Het |
| Wdr36 |
A |
G |
18: 32,986,021 (GRCm39) |
D575G |
possibly damaging |
Het |
| Zfp292 |
G |
T |
4: 34,805,397 (GRCm39) |
A2549E |
possibly damaging |
Het |
| Zfp354a |
A |
T |
11: 50,961,073 (GRCm39) |
H426L |
probably damaging |
Het |
| Zfp407 |
C |
T |
18: 84,577,898 (GRCm39) |
A1072T |
probably benign |
Het |
| Zfp648 |
T |
A |
1: 154,081,119 (GRCm39) |
I426N |
probably damaging |
Het |
| Zfp87 |
T |
C |
13: 74,520,736 (GRCm39) |
N114S |
probably benign |
Het |
|
| Other mutations in Ppl |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00231:Ppl
|
APN |
16 |
4,907,409 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL00484:Ppl
|
APN |
16 |
4,905,816 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL00654:Ppl
|
APN |
16 |
4,905,172 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00832:Ppl
|
APN |
16 |
4,906,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01104:Ppl
|
APN |
16 |
4,912,355 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01327:Ppl
|
APN |
16 |
4,905,508 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01644:Ppl
|
APN |
16 |
4,909,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01824:Ppl
|
APN |
16 |
4,905,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02071:Ppl
|
APN |
16 |
4,930,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02085:Ppl
|
APN |
16 |
4,907,680 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02282:Ppl
|
APN |
16 |
4,919,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02635:Ppl
|
APN |
16 |
4,907,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02649:Ppl
|
APN |
16 |
4,905,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02888:Ppl
|
APN |
16 |
4,918,271 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL03305:Ppl
|
APN |
16 |
4,911,097 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
G4846:Ppl
|
UTSW |
16 |
4,905,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03097:Ppl
|
UTSW |
16 |
4,914,590 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0759:Ppl
|
UTSW |
16 |
4,907,641 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0786:Ppl
|
UTSW |
16 |
4,906,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1024:Ppl
|
UTSW |
16 |
4,917,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Ppl
|
UTSW |
16 |
4,920,461 (GRCm39) |
nonsense |
probably null |
|
|
R1597:Ppl
|
UTSW |
16 |
4,925,438 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1863:Ppl
|
UTSW |
16 |
4,905,844 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1921:Ppl
|
UTSW |
16 |
4,923,988 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2230:Ppl
|
UTSW |
16 |
4,906,845 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R2275:Ppl
|
UTSW |
16 |
4,912,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2355:Ppl
|
UTSW |
16 |
4,912,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3410:Ppl
|
UTSW |
16 |
4,925,381 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3737:Ppl
|
UTSW |
16 |
4,924,721 (GRCm39) |
missense |
probably benign |
|
|
R3797:Ppl
|
UTSW |
16 |
4,922,414 (GRCm39) |
splice site |
probably benign |
|
|
R3968:Ppl
|
UTSW |
16 |
4,918,196 (GRCm39) |
splice site |
probably null |
|
|
R3970:Ppl
|
UTSW |
16 |
4,918,196 (GRCm39) |
splice site |
probably null |
|
|
R4034:Ppl
|
UTSW |
16 |
4,924,721 (GRCm39) |
missense |
probably benign |
|
|
R4583:Ppl
|
UTSW |
16 |
4,922,400 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4639:Ppl
|
UTSW |
16 |
4,907,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4762:Ppl
|
UTSW |
16 |
4,906,846 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4828:Ppl
|
UTSW |
16 |
4,922,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4869:Ppl
|
UTSW |
16 |
4,922,753 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4925:Ppl
|
UTSW |
16 |
4,922,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4983:Ppl
|
UTSW |
16 |
4,906,582 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4984:Ppl
|
UTSW |
16 |
4,905,505 (GRCm39) |
missense |
probably benign |
|
|
R4997:Ppl
|
UTSW |
16 |
4,907,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Ppl
|
UTSW |
16 |
4,906,742 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5073:Ppl
|
UTSW |
16 |
4,906,742 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5074:Ppl
|
UTSW |
16 |
4,906,742 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5286:Ppl
|
UTSW |
16 |
4,906,987 (GRCm39) |
nonsense |
probably null |
|
|
R5398:Ppl
|
UTSW |
16 |
4,922,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5448:Ppl
|
UTSW |
16 |
4,925,430 (GRCm39) |
missense |
probably benign |
|
|
R5664:Ppl
|
UTSW |
16 |
4,923,919 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5873:Ppl
|
UTSW |
16 |
4,923,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5918:Ppl
|
UTSW |
16 |
4,922,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5951:Ppl
|
UTSW |
16 |
4,906,492 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6038:Ppl
|
UTSW |
16 |
4,920,445 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6038:Ppl
|
UTSW |
16 |
4,920,445 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6088:Ppl
|
UTSW |
16 |
4,922,852 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6149:Ppl
|
UTSW |
16 |
4,925,460 (GRCm39) |
nonsense |
probably null |
|
|
R6358:Ppl
|
UTSW |
16 |
4,905,793 (GRCm39) |
nonsense |
probably null |
|
|
R6379:Ppl
|
UTSW |
16 |
4,915,555 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6468:Ppl
|
UTSW |
16 |
4,910,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6514:Ppl
|
UTSW |
16 |
4,905,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6528:Ppl
|
UTSW |
16 |
4,905,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6703:Ppl
|
UTSW |
16 |
4,907,328 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6721:Ppl
|
UTSW |
16 |
4,925,333 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6811:Ppl
|
UTSW |
16 |
4,907,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6934:Ppl
|
UTSW |
16 |
4,912,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Ppl
|
UTSW |
16 |
4,905,366 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7076:Ppl
|
UTSW |
16 |
4,917,983 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7300:Ppl
|
UTSW |
16 |
4,920,235 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7349:Ppl
|
UTSW |
16 |
4,922,593 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7359:Ppl
|
UTSW |
16 |
4,907,205 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7378:Ppl
|
UTSW |
16 |
4,930,860 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7383:Ppl
|
UTSW |
16 |
4,915,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7389:Ppl
|
UTSW |
16 |
4,924,577 (GRCm39) |
splice site |
probably null |
|
|
R7445:Ppl
|
UTSW |
16 |
4,906,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7687:Ppl
|
UTSW |
16 |
4,915,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7752:Ppl
|
UTSW |
16 |
4,920,166 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7827:Ppl
|
UTSW |
16 |
4,905,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7836:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7896:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7898:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7943:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8122:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8126:Ppl
|
UTSW |
16 |
4,906,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8284:Ppl
|
UTSW |
16 |
4,950,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Ppl
|
UTSW |
16 |
4,905,300 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8781:Ppl
|
UTSW |
16 |
4,915,800 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8835:Ppl
|
UTSW |
16 |
4,906,854 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8836:Ppl
|
UTSW |
16 |
4,906,854 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8837:Ppl
|
UTSW |
16 |
4,906,854 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8866:Ppl
|
UTSW |
16 |
4,920,211 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8894:Ppl
|
UTSW |
16 |
4,925,206 (GRCm39) |
intron |
probably benign |
|
|
R8922:Ppl
|
UTSW |
16 |
4,923,815 (GRCm39) |
missense |
probably benign |
|
|
R8927:Ppl
|
UTSW |
16 |
4,905,474 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8928:Ppl
|
UTSW |
16 |
4,905,474 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9070:Ppl
|
UTSW |
16 |
4,907,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9314:Ppl
|
UTSW |
16 |
4,922,367 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9642:Ppl
|
UTSW |
16 |
4,915,602 (GRCm39) |
missense |
probably benign |
0.01 |
|
RF009:Ppl
|
UTSW |
16 |
4,915,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0054:Ppl
|
UTSW |
16 |
4,922,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Ppl
|
UTSW |
16 |
4,907,371 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ppl
|
UTSW |
16 |
4,924,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Ppl
|
UTSW |
16 |
4,915,821 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCAGGTTCAGGTACTCCTTCCAC -3'
(R):5'- AGCCAAGCCGATTCTGTCTTCAC -3'
Sequencing Primer
(F):5'- ACAGCCTCCATGTGTGCC -3'
(R):5'- TGCACCAATGAGCTGTACTG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation