Mutagenetix > Incidental Mutation

Incidental Mutation 'R1538:Fcgbpl1'

169686

Institutional Source

Beutler Lab

Gene Symbol

Fcgbpl1

Ensembl Gene

ENSMUSG00000078776

Gene Name

Fc fragment of IgG binding protein like 1

Synonyms

9530053A07Rik

MMRRC Submission

039577-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.103) question?

Stock #

R1538 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

27828891-27864236 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 27854917 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 1848 (I1848F)

Ref Sequence

ENSEMBL: ENSMUSP00000114986 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059886] [ENSMUST00000150948]

AlphaFold

E9PVG8

Predicted Effect

probably damaging
Transcript: ENSMUST00000059886
AA Change: I1848F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000056479
Gene: ENSMUSG00000078776
AA Change: I1848F

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000150948
AA Change: I1848F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000114986
Gene: ENSMUSG00000078776
AA Change: I1848F

Domain	Start	End	E-Value	Type
low complexity region	8	24	N/A	INTRINSIC
FOLN	27	49	1.23e-4	SMART
VWD	46	211	1.5e-40	SMART
C8	251	326	4.31e-33	SMART
Pfam:TIL	329	383	2e-13	PFAM
VWC	385	448	1.02e0	SMART
VWD	439	603	4.32e-32	SMART
C8	640	715	4.54e-9	SMART
Pfam:TIL	718	771	1.6e-12	PFAM
VWC	773	826	1.1e0	SMART
FOLN	805	827	6.87e1	SMART
VWD	825	988	7.92e-40	SMART
C8	1033	1108	5.1e-35	SMART
Pfam:TIL	1111	1164	7.6e-11	PFAM
VWC	1166	1224	1.1e-2	SMART
FOLN	1197	1219	9.55e-1	SMART
FOLN	1223	1245	5.38e1	SMART
VWD	1241	1410	9.04e-35	SMART
C8	1450	1526	9.54e-26	SMART
low complexity region	1540	1550	N/A	INTRINSIC
EGF_like	1557	1580	5.34e1	SMART
VWC	1588	1681	3.21e-3	SMART
VWD	1639	1806	7.3e-30	SMART
C8	1838	1913	2.44e-32	SMART
EGF_like	1941	1964	4.46e1	SMART
VWC	1971	2062	2.85e-1	SMART
VWD	2022	2178	1.32e-27	SMART
low complexity region	2199	2212	N/A	INTRINSIC
C8	2219	2294	1.43e-29	SMART
Pfam:TIL	2297	2350	1.1e-11	PFAM
FOLN	2383	2405	5.68e1	SMART
VWD	2402	2564	4.58e-4	SMART

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.5%
20x: 89.6%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 104 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	G	T	3: 137,771,162 (GRCm39)	R117L	probably benign	Het
4930447C04Rik	G	A	12: 72,928,120 (GRCm39)	A537V	possibly damaging	Het
4930579F01Rik	A	C	3: 137,889,517 (GRCm39)	D33E	probably damaging	Het
Acnat1	T	C	4: 49,447,835 (GRCm39)	K249E	possibly damaging	Het
Ankrd13a	T	C	5: 114,942,295 (GRCm39)	I526T	possibly damaging	Het
Aplp1	C	A	7: 30,135,452 (GRCm39)	E535D	probably benign	Het
Armc8	T	A	9: 99,387,343 (GRCm39)	H425L	probably damaging	Het
Arsi	G	A	18: 61,049,723 (GRCm39)	G202E	probably benign	Het
Asprv1	C	T	6: 86,605,618 (GRCm39)	Q155*	probably null	Het
Atl1	A	G	12: 69,972,962 (GRCm39)	Q94R	probably benign	Het
Atp2a2	A	G	5: 122,595,440 (GRCm39)	L970P	probably damaging	Het
Atp8a2	T	C	14: 60,097,719 (GRCm39)	K770E	probably benign	Het
Bod1l	A	G	5: 41,973,772 (GRCm39)	M2514T	probably benign	Het
Cacfd1	T	A	2: 26,908,951 (GRCm39)	D97E	probably benign	Het
Cacna1e	A	G	1: 154,437,504 (GRCm39)	L344P	probably damaging	Het
Cacna2d2	C	A	9: 107,394,615 (GRCm39)	R596S	probably damaging	Het
Catip	C	A	1: 74,403,811 (GRCm39)	S176*	probably null	Het
Cdcp1	G	A	9: 123,002,653 (GRCm39)	S806L	probably damaging	Het
Cdk6	A	T	5: 3,570,675 (GRCm39)	I289L	probably benign	Het
Cers3	C	T	7: 66,431,571 (GRCm39)	T182I	probably damaging	Het
Cfap46	T	A	7: 139,262,924 (GRCm39)	N43I	probably null	Het
Clec4n	A	T	6: 123,206,992 (GRCm39)	R5S	possibly damaging	Het
Cnr2	G	T	4: 135,644,012 (GRCm39)	S30I	probably benign	Het
Col18a1	C	T	10: 76,907,170 (GRCm39)	G870E	probably damaging	Het
Cpne6	T	C	14: 55,752,677 (GRCm39)	V289A	possibly damaging	Het
Crym	G	A	7: 119,796,938 (GRCm39)	L141F	probably benign	Het
Cxxc5	T	C	18: 35,991,622 (GRCm39)	S8P	unknown	Het
Dido1	A	C	2: 180,326,763 (GRCm39)	S453R	possibly damaging	Het
Dnah2	A	C	11: 69,368,028 (GRCm39)	S1770R	probably benign	Het
Dnah7a	A	G	1: 53,535,148 (GRCm39)	V2704A	possibly damaging	Het
Eml5	T	C	12: 98,760,535 (GRCm39)	N1738S	probably damaging	Het
Eri3	A	G	4: 117,439,836 (GRCm39)	T138A	possibly damaging	Het
Ext2	C	T	2: 93,537,632 (GRCm39)	E585K	probably damaging	Het
Fbxw19	T	A	9: 109,324,056 (GRCm39)	S38C	probably damaging	Het
Fmo6	G	A	1: 162,753,675 (GRCm39)	P156S	probably damaging	Het
Frem3	A	T	8: 81,339,764 (GRCm39)	I686F	probably benign	Het
Frem3	T	C	8: 81,339,339 (GRCm39)	L544P	probably damaging	Het
Gabra1	T	C	11: 42,031,177 (GRCm39)	Y251C	probably benign	Het
Gemin4	G	T	11: 76,101,987 (GRCm39)	Q925K	probably benign	Het
Gm18856	T	A	13: 14,139,274 (GRCm39)		probably benign	Het
Gnb1	A	T	4: 155,636,171 (GRCm39)	T164S	probably benign	Het
Gpx6	A	G	13: 21,497,822 (GRCm39)	D31G	possibly damaging	Het
Gzmd	A	C	14: 56,367,802 (GRCm39)	I157S	probably benign	Het
Il31ra	T	A	13: 112,684,000 (GRCm39)	N43I	possibly damaging	Het
Irak3	T	C	10: 120,001,035 (GRCm39)	T297A	probably benign	Het
Kank2	T	C	9: 21,685,927 (GRCm39)	D649G	probably damaging	Het
Kif3b	AGAGGAGGAGGAGGAGG	AGAGGAGGAGGAGG	2: 153,159,382 (GRCm39)		probably benign	Het
Kirrel1	C	T	3: 86,996,458 (GRCm39)	M380I	probably null	Het
Klhl18	A	G	9: 110,275,815 (GRCm39)	F111S	probably damaging	Het
Lratd2	A	G	15: 60,695,498 (GRCm39)	C83R	probably damaging	Het
Lrp5	A	G	19: 3,697,585 (GRCm39)	S319P	possibly damaging	Het
Mettl15	T	C	2: 108,962,010 (GRCm39)		probably null	Het
Mtarc1	T	C	1: 184,534,199 (GRCm39)	E223G	probably damaging	Het
Ncoa1	T	C	12: 4,320,748 (GRCm39)	Q1107R	possibly damaging	Het
Ncoa7	T	G	10: 30,570,207 (GRCm39)	M251L	probably damaging	Het
Nos2	A	T	11: 78,847,396 (GRCm39)	M1023L	probably benign	Het
Nup107	T	C	10: 117,626,399 (GRCm39)	K25E	probably damaging	Het
Or10q1b	A	T	19: 13,682,860 (GRCm39)	Y223F	probably damaging	Het
Or52s1b	A	G	7: 102,822,193 (GRCm39)	I217T	probably damaging	Het
Or5k14	T	A	16: 58,693,261 (GRCm39)	N84I	probably damaging	Het
Or5p58	T	A	7: 107,694,493 (GRCm39)	I95F	probably damaging	Het
Or6b6	A	T	7: 106,571,190 (GRCm39)	Y120*	probably null	Het
Or6c206	T	C	10: 129,097,082 (GRCm39)	I84T	probably damaging	Het
Parm1	G	A	5: 91,742,306 (GRCm39)	E225K	possibly damaging	Het
Pdzd2	A	C	15: 12,373,047 (GRCm39)	S2363A	probably damaging	Het
Piezo1	A	G	8: 123,218,142 (GRCm39)	L1199P	probably damaging	Het
Prpsap1	A	T	11: 116,370,534 (GRCm39)	M141K	probably benign	Het
Prss29	A	T	17: 25,539,257 (GRCm39)	M1L	possibly damaging	Het
Pter	T	A	2: 12,983,417 (GRCm39)	S141T	probably benign	Het
Ptpru	A	T	4: 131,501,662 (GRCm39)	D1181E	probably damaging	Het
Rab3ip	T	A	10: 116,775,159 (GRCm39)	Q66H	probably damaging	Het
Rgs12	A	T	5: 35,178,511 (GRCm39)	T779S	probably damaging	Het
Rgs22	A	G	15: 36,048,922 (GRCm39)	F786S	probably damaging	Het
Rnasel	A	T	1: 153,636,540 (GRCm39)	D640V	possibly damaging	Het
Rp1	T	C	1: 4,415,899 (GRCm39)	T1738A	probably damaging	Het
Sacs	T	C	14: 61,447,508 (GRCm39)	S3185P	probably damaging	Het
Scnn1a	T	A	6: 125,315,856 (GRCm39)	D321E	possibly damaging	Het
Sec31b	G	C	19: 44,507,025 (GRCm39)	L1014V	probably benign	Het
Serpinb10	A	G	1: 107,468,690 (GRCm39)	Y111C	probably damaging	Het
Shld2	C	G	14: 33,990,833 (GRCm39)	Q24H	probably damaging	Het
Siglecg	A	G	7: 43,067,313 (GRCm39)	K627E	possibly damaging	Het
Sigmar1	T	C	4: 41,740,845 (GRCm39)	I95V	probably benign	Het
Sirpb1b	T	A	3: 15,613,819 (GRCm39)	T88S	possibly damaging	Het
Spire2	T	G	8: 124,084,895 (GRCm39)	L245R	probably damaging	Het
Stard9	C	A	2: 120,527,192 (GRCm39)	P1150T	probably benign	Het
Stat6	C	A	10: 127,489,125 (GRCm39)	T380N	probably damaging	Het
Sult3a1	G	A	10: 33,746,166 (GRCm39)	G162E	probably benign	Het
Surf4	T	C	2: 26,823,710 (GRCm39)		probably null	Het
Tacc2	T	C	7: 130,227,149 (GRCm39)	M1278T	probably benign	Het
Tacr2	T	A	10: 62,097,106 (GRCm39)		probably null	Het
Tcaf1	A	T	6: 42,655,923 (GRCm39)	V351E	probably damaging	Het
Tmcc2	A	G	1: 132,308,718 (GRCm39)	S59P	probably damaging	Het
Tmem17	G	A	11: 22,467,266 (GRCm39)	S60N	possibly damaging	Het
Tmem63b	C	G	17: 45,989,904 (GRCm39)	R88P	possibly damaging	Het
Tmprss7	A	T	16: 45,499,753 (GRCm39)	I307N	probably benign	Het
Treml2	A	T	17: 48,609,786 (GRCm39)	T73S	possibly damaging	Het
Trrap	A	G	5: 144,774,012 (GRCm39)	H2876R	possibly damaging	Het
Tyw3	A	G	3: 154,302,506 (GRCm39)	I53T	probably damaging	Het
Ugp2	A	G	11: 21,283,791 (GRCm39)	I92T	possibly damaging	Het
Vmn2r66	A	T	7: 84,644,166 (GRCm39)	M748K	possibly damaging	Het
Vmn2r82	T	C	10: 79,192,578 (GRCm39)	S52P	possibly damaging	Het
Wdr37	A	T	13: 8,886,828 (GRCm39)	S320T	probably benign	Het
Zbtb16	A	T	9: 48,743,583 (GRCm39)	M243K	probably benign	Het
Zfr	C	T	15: 12,150,329 (GRCm39)	T432I	possibly damaging	Het

Other mutations in Fcgbpl1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00435:Fcgbpl1	APN	7	27,863,953 (GRCm39)	missense	probably damaging	1.00
IGL00757:Fcgbpl1	APN	7	27,853,870 (GRCm39)	missense	probably damaging	1.00
IGL01015:Fcgbpl1	APN	7	27,854,743 (GRCm39)	missense	probably damaging	1.00
IGL01079:Fcgbpl1	APN	7	27,839,203 (GRCm39)	missense	probably damaging	0.99
IGL01343:Fcgbpl1	APN	7	27,850,127 (GRCm39)	missense	probably benign	0.19
IGL01420:Fcgbpl1	APN	7	27,839,558 (GRCm39)	missense	probably benign	0.28
IGL01604:Fcgbpl1	APN	7	27,854,749 (GRCm39)	missense	probably benign	0.11
IGL01666:Fcgbpl1	APN	7	27,852,717 (GRCm39)	missense	probably damaging	1.00
IGL02002:Fcgbpl1	APN	7	27,852,221 (GRCm39)	missense	probably damaging	1.00
IGL02036:Fcgbpl1	APN	7	27,836,950 (GRCm39)	missense	possibly damaging	0.82
IGL02126:Fcgbpl1	APN	7	27,839,281 (GRCm39)	missense	probably damaging	1.00
IGL02150:Fcgbpl1	APN	7	27,846,204 (GRCm39)	nonsense	probably null
IGL02219:Fcgbpl1	APN	7	27,854,060 (GRCm39)	missense	probably damaging	1.00
IGL02563:Fcgbpl1	APN	7	27,857,317 (GRCm39)	missense	probably benign
IGL02804:Fcgbpl1	APN	7	27,852,795 (GRCm39)	missense	probably benign	0.00
IGL02830:Fcgbpl1	APN	7	27,862,348 (GRCm39)	missense	probably damaging	1.00
IGL02943:Fcgbpl1	APN	7	27,846,613 (GRCm39)	missense	probably damaging	1.00
IGL02977:Fcgbpl1	APN	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
IGL03231:Fcgbpl1	APN	7	27,853,147 (GRCm39)	missense	possibly damaging	0.95
IGL03304:Fcgbpl1	APN	7	27,841,667 (GRCm39)	missense	probably damaging	0.99
herz	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
pulse	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
Sinusoidal	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Fcgbpl1	UTSW	7	27,853,889 (GRCm39)	missense	possibly damaging	0.61
R0023:Fcgbpl1	UTSW	7	27,852,837 (GRCm39)	missense	probably benign	0.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0131:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0132:Fcgbpl1	UTSW	7	27,837,040 (GRCm39)	missense	probably damaging	1.00
R0158:Fcgbpl1	UTSW	7	27,854,917 (GRCm39)	missense	probably damaging	1.00
R0230:Fcgbpl1	UTSW	7	27,856,250 (GRCm39)	missense	probably damaging	1.00
R0310:Fcgbpl1	UTSW	7	27,841,699 (GRCm39)	missense	probably benign	0.04
R0448:Fcgbpl1	UTSW	7	27,839,660 (GRCm39)	missense	probably benign	0.03
R0462:Fcgbpl1	UTSW	7	27,836,765 (GRCm39)	missense	probably damaging	1.00
R0481:Fcgbpl1	UTSW	7	27,853,174 (GRCm39)	missense	probably damaging	1.00
R0497:Fcgbpl1	UTSW	7	27,846,890 (GRCm39)	missense	probably damaging	1.00
R0556:Fcgbpl1	UTSW	7	27,858,803 (GRCm39)	missense	probably benign
R0562:Fcgbpl1	UTSW	7	27,862,115 (GRCm39)	missense	probably benign	0.30
R0586:Fcgbpl1	UTSW	7	27,836,516 (GRCm39)	missense	probably damaging	0.99
R0924:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R0930:Fcgbpl1	UTSW	7	27,839,555 (GRCm39)	missense	probably damaging	1.00
R1103:Fcgbpl1	UTSW	7	27,853,945 (GRCm39)	missense	probably damaging	1.00
R1213:Fcgbpl1	UTSW	7	27,857,098 (GRCm39)	missense	probably damaging	1.00
R1292:Fcgbpl1	UTSW	7	27,842,219 (GRCm39)	splice site	probably benign
R1368:Fcgbpl1	UTSW	7	27,858,903 (GRCm39)	missense	possibly damaging	0.89
R1451:Fcgbpl1	UTSW	7	27,836,582 (GRCm39)	missense	probably damaging	1.00
R1477:Fcgbpl1	UTSW	7	27,856,518 (GRCm39)	missense	probably benign	0.01
R1655:Fcgbpl1	UTSW	7	27,846,535 (GRCm39)	missense	probably damaging	0.98
R1697:Fcgbpl1	UTSW	7	27,853,772 (GRCm39)	missense	probably damaging	1.00
R1741:Fcgbpl1	UTSW	7	27,857,279 (GRCm39)	missense	probably damaging	0.98
R1796:Fcgbpl1	UTSW	7	27,854,797 (GRCm39)	missense	probably damaging	1.00
R1853:Fcgbpl1	UTSW	7	27,854,971 (GRCm39)	nonsense	probably null
R1861:Fcgbpl1	UTSW	7	27,854,157 (GRCm39)	missense	probably damaging	1.00
R1909:Fcgbpl1	UTSW	7	27,843,773 (GRCm39)	missense	possibly damaging	0.52
R1971:Fcgbpl1	UTSW	7	27,830,937 (GRCm39)	missense	possibly damaging	0.90
R1990:Fcgbpl1	UTSW	7	27,853,785 (GRCm39)	missense	probably damaging	0.98
R2020:Fcgbpl1	UTSW	7	27,855,019 (GRCm39)	missense	probably benign
R2084:Fcgbpl1	UTSW	7	27,856,960 (GRCm39)	missense	probably damaging	1.00
R2125:Fcgbpl1	UTSW	7	27,857,447 (GRCm39)	missense	probably benign	0.00
R2132:Fcgbpl1	UTSW	7	27,854,899 (GRCm39)	missense	probably damaging	1.00
R2513:Fcgbpl1	UTSW	7	27,831,060 (GRCm39)	missense	probably damaging	0.99
R2913:Fcgbpl1	UTSW	7	27,863,732 (GRCm39)	missense	probably damaging	1.00
R3150:Fcgbpl1	UTSW	7	27,853,620 (GRCm39)	missense	probably benign	0.21
R3499:Fcgbpl1	UTSW	7	27,853,980 (GRCm39)	missense	probably benign	0.42
R3702:Fcgbpl1	UTSW	7	27,857,203 (GRCm39)	missense	probably damaging	1.00
R3881:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R3938:Fcgbpl1	UTSW	7	27,853,719 (GRCm39)	missense	probably damaging	1.00
R4050:Fcgbpl1	UTSW	7	27,852,410 (GRCm39)	missense	possibly damaging	0.55
R4152:Fcgbpl1	UTSW	7	27,856,322 (GRCm39)	missense	possibly damaging	0.47
R4168:Fcgbpl1	UTSW	7	27,836,534 (GRCm39)	missense	probably benign	0.05
R4235:Fcgbpl1	UTSW	7	27,856,073 (GRCm39)	missense	probably damaging	0.99
R4241:Fcgbpl1	UTSW	7	27,853,760 (GRCm39)	missense	probably damaging	1.00
R4363:Fcgbpl1	UTSW	7	27,846,331 (GRCm39)	missense	probably damaging	1.00
R4460:Fcgbpl1	UTSW	7	27,852,281 (GRCm39)	missense	probably benign	0.17
R4463:Fcgbpl1	UTSW	7	27,850,144 (GRCm39)	missense	probably benign
R4841:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4842:Fcgbpl1	UTSW	7	27,850,147 (GRCm39)	missense	probably damaging	1.00
R4876:Fcgbpl1	UTSW	7	27,842,225 (GRCm39)	intron	probably benign
R4905:Fcgbpl1	UTSW	7	27,856,408 (GRCm39)	missense	possibly damaging	0.93
R4997:Fcgbpl1	UTSW	7	27,843,349 (GRCm39)	missense	possibly damaging	0.77
R5091:Fcgbpl1	UTSW	7	27,856,383 (GRCm39)	missense	probably benign	0.44
R5159:Fcgbpl1	UTSW	7	27,852,733 (GRCm39)	missense	probably benign	0.09
R5326:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5396:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign
R5441:Fcgbpl1	UTSW	7	27,856,339 (GRCm39)	missense	probably damaging	1.00
R5480:Fcgbpl1	UTSW	7	27,857,424 (GRCm39)	nonsense	probably null
R5542:Fcgbpl1	UTSW	7	27,854,914 (GRCm39)	missense	probably damaging	0.98
R5571:Fcgbpl1	UTSW	7	27,855,994 (GRCm39)	missense	probably damaging	0.99
R5613:Fcgbpl1	UTSW	7	27,842,303 (GRCm39)	intron	probably benign
R5637:Fcgbpl1	UTSW	7	27,852,277 (GRCm39)	missense	probably benign	0.00
R5766:Fcgbpl1	UTSW	7	27,836,754 (GRCm39)	nonsense	probably null
R6174:Fcgbpl1	UTSW	7	27,839,384 (GRCm39)	missense	probably damaging	0.96
R6233:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R6250:Fcgbpl1	UTSW	7	27,850,139 (GRCm39)	missense	probably damaging	1.00
R6379:Fcgbpl1	UTSW	7	27,857,017 (GRCm39)	missense	probably damaging	1.00
R6442:Fcgbpl1	UTSW	7	27,843,611 (GRCm39)	missense	possibly damaging	0.88
R6478:Fcgbpl1	UTSW	7	27,854,798 (GRCm39)	missense	probably damaging	1.00
R6699:Fcgbpl1	UTSW	7	27,843,793 (GRCm39)	missense	probably damaging	1.00
R6852:Fcgbpl1	UTSW	7	27,846,560 (GRCm39)	missense	probably damaging	1.00
R6883:Fcgbpl1	UTSW	7	27,852,260 (GRCm39)	missense	possibly damaging	0.89
R6902:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6903:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6904:Fcgbpl1	UTSW	7	27,836,638 (GRCm39)	missense	probably damaging	1.00
R6992:Fcgbpl1	UTSW	7	27,839,608 (GRCm39)	missense	probably benign	0.04
R7023:Fcgbpl1	UTSW	7	27,839,463 (GRCm39)	nonsense	probably null
R7039:Fcgbpl1	UTSW	7	27,839,573 (GRCm39)	missense	possibly damaging	0.80
R7171:Fcgbpl1	UTSW	7	27,853,944 (GRCm39)	nonsense	probably null
R7282:Fcgbpl1	UTSW	7	27,843,833 (GRCm39)	missense	probably benign	0.02
R7291:Fcgbpl1	UTSW	7	27,839,645 (GRCm39)	missense	probably benign
R7344:Fcgbpl1	UTSW	7	27,852,185 (GRCm39)	missense	possibly damaging	0.46
R7344:Fcgbpl1	UTSW	7	27,839,704 (GRCm39)	missense	possibly damaging	0.79
R7392:Fcgbpl1	UTSW	7	27,863,797 (GRCm39)	missense	possibly damaging	0.83
R7531:Fcgbpl1	UTSW	7	27,839,656 (GRCm39)	missense	probably benign
R7541:Fcgbpl1	UTSW	7	27,843,681 (GRCm39)	nonsense	probably null
R7577:Fcgbpl1	UTSW	7	27,853,848 (GRCm39)	missense	possibly damaging	0.65
R7594:Fcgbpl1	UTSW	7	27,830,885 (GRCm39)	missense	probably damaging	0.99
R7647:Fcgbpl1	UTSW	7	27,839,470 (GRCm39)	missense	probably benign	0.00
R7718:Fcgbpl1	UTSW	7	27,846,626 (GRCm39)	missense	probably damaging	1.00
R7733:Fcgbpl1	UTSW	7	27,839,390 (GRCm39)	missense	probably damaging	1.00
R7737:Fcgbpl1	UTSW	7	27,856,498 (GRCm39)	missense	probably damaging	1.00
R7908:Fcgbpl1	UTSW	7	27,846,921 (GRCm39)	missense	probably benign	0.12
R8013:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8014:Fcgbpl1	UTSW	7	27,836,966 (GRCm39)	missense	probably benign	0.14
R8151:Fcgbpl1	UTSW	7	27,852,766 (GRCm39)	missense	possibly damaging	0.95
R8175:Fcgbpl1	UTSW	7	27,863,873 (GRCm39)	nonsense	probably null
R8254:Fcgbpl1	UTSW	7	27,846,774 (GRCm39)	missense	possibly damaging	0.63
R8345:Fcgbpl1	UTSW	7	27,854,785 (GRCm39)	missense	probably damaging	1.00
R8414:Fcgbpl1	UTSW	7	27,842,158 (GRCm39)	missense	probably damaging	1.00
R8419:Fcgbpl1	UTSW	7	27,843,346 (GRCm39)	missense	probably damaging	1.00
R8496:Fcgbpl1	UTSW	7	27,843,377 (GRCm39)	missense	possibly damaging	0.81
R8691:Fcgbpl1	UTSW	7	27,853,264 (GRCm39)	missense	possibly damaging	0.72
R8785:Fcgbpl1	UTSW	7	27,854,132 (GRCm39)	missense	probably damaging	1.00
R8863:Fcgbpl1	UTSW	7	27,831,006 (GRCm39)	missense	probably damaging	1.00
R8926:Fcgbpl1	UTSW	7	27,853,869 (GRCm39)	missense	probably damaging	1.00
R8950:Fcgbpl1	UTSW	7	27,863,751 (GRCm39)	missense	probably benign	0.32
R9014:Fcgbpl1	UTSW	7	27,854,876 (GRCm39)	missense	probably damaging	1.00
R9045:Fcgbpl1	UTSW	7	27,853,856 (GRCm39)	missense	probably damaging	1.00
R9115:Fcgbpl1	UTSW	7	27,853,754 (GRCm39)	missense	possibly damaging	0.74
R9233:Fcgbpl1	UTSW	7	27,839,519 (GRCm39)	missense	possibly damaging	0.83
R9330:Fcgbpl1	UTSW	7	27,856,410 (GRCm39)	missense	probably benign	0.02
R9426:Fcgbpl1	UTSW	7	27,843,281 (GRCm39)	missense	possibly damaging	0.92
R9477:Fcgbpl1	UTSW	7	27,852,265 (GRCm39)	missense	probably damaging	1.00
R9502:Fcgbpl1	UTSW	7	27,836,891 (GRCm39)	missense	probably benign	0.09
R9505:Fcgbpl1	UTSW	7	27,841,909 (GRCm39)	nonsense	probably null
R9601:Fcgbpl1	UTSW	7	27,853,805 (GRCm39)	missense	possibly damaging	0.78
R9630:Fcgbpl1	UTSW	7	27,836,624 (GRCm39)	missense	probably damaging	1.00
R9632:Fcgbpl1	UTSW	7	27,841,726 (GRCm39)	missense	probably benign
R9673:Fcgbpl1	UTSW	7	27,856,044 (GRCm39)	missense	probably benign	0.25
R9735:Fcgbpl1	UTSW	7	27,856,435 (GRCm39)	missense	probably damaging	1.00
Z1176:Fcgbpl1	UTSW	7	27,854,187 (GRCm39)	missense	probably benign	0.03
Z1176:Fcgbpl1	UTSW	7	27,841,811 (GRCm39)	missense	probably benign	0.06
Z1177:Fcgbpl1	UTSW	7	27,839,323 (GRCm39)	missense	probably benign	0.25
Z1186:Fcgbpl1	UTSW	7	27,856,411 (GRCm39)	missense	probably benign	0.01
Z1186:Fcgbpl1	UTSW	7	27,846,130 (GRCm39)	missense	probably benign	0.00
Z1186:Fcgbpl1	UTSW	7	27,830,997 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CTCCTTGTTCACCTAAGTGGCATGG -3'
(R):5'- TTCTCTAAGTCGGACCCTGGCATC -3'

Sequencing Primer
(F):5'- TGGAAACAGTTTCATGCGCC -3'
(R):5'- TCCTGACATGCTGCCACATAG -3'

Posted On

2014-04-13