Mutagenetix > Incidental Mutation

Incidental Mutation 'R1554:Dnah11'

170181

Institutional Source

Beutler Lab

Gene Symbol

Dnah11

Ensembl Gene

ENSMUSG00000018581

Gene Name

dynein, axonemal, heavy chain 11

Synonyms

b2b598Clo, Dnahc11, b2b1289Clo, lrd, b2b1727Clo, b2b1203Clo, b2b1279Clo

MMRRC Submission

039593-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.492) question?

Stock #

R1554 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

117877982-118199043 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 118082499 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 1735 (V1735I)

Ref Sequence

ENSEMBL: ENSMUSP00000081867 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000084806]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000084806
AA Change: V1735I

PolyPhen 2 Score 0.922 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000081867
Gene: ENSMUSG00000018581
AA Change: V1735I

Domain	Start	End	E-Value	Type
low complexity region	18	28	N/A	INTRINSIC
Pfam:DHC_N1	218	794	1.6e-162	PFAM
low complexity region	1266	1282	N/A	INTRINSIC
Pfam:DHC_N2	1297	1705	1e-130	PFAM
low complexity region	1757	1773	N/A	INTRINSIC
AAA	1869	1963	1.51e0	SMART
Pfam:AAA_5	2150	2286	1.6e-12	PFAM
AAA	2474	2619	1.48e-1	SMART
AAA	2819	2931	4.57e-1	SMART
Pfam:MT	3069	3413	3.2e-162	PFAM
Pfam:AAA_9	3434	3656	2.9e-88	PFAM
Pfam:Dynein_heavy	3790	4486	7.1e-235	PFAM

Coding Region Coverage

1x: 99.0%
3x: 98.0%
10x: 95.2%
20x: 89.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
PHENOTYPE: Approximately half of live-born homozygous mutants show situs inversus indicating that this gene is no longer properly controlling left-right asymmetry. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A1cf	T	A	19: 31,908,902 (GRCm38)	D70E	possibly damaging	Het
Adamts7	A	T	9: 90,173,650 (GRCm38)	D152V	probably damaging	Het
Api5	T	C	2: 94,425,643 (GRCm38)	D233G	probably benign	Het
Btaf1	A	G	19: 36,996,598 (GRCm38)	D1390G	probably benign	Het
Cep135	G	A	5: 76,634,213 (GRCm38)	W893*	probably null	Het
Cmtm6	T	A	9: 114,746,482 (GRCm38)	V153D	possibly damaging	Het
Dnm1l	T	C	16: 16,341,426 (GRCm38)	N104S	probably benign	Het
Dpyd	A	T	3: 119,065,046 (GRCm38)		probably null	Het
Dtx1	T	C	5: 120,683,321 (GRCm38)	K387R	probably damaging	Het
Ercc4	A	G	16: 13,147,622 (GRCm38)	D706G	probably damaging	Het
Fam208b	A	G	13: 3,576,374 (GRCm38)	V1192A	possibly damaging	Het
Fat2	T	C	11: 55,253,664 (GRCm38)	N4128S	probably benign	Het
Gm42669	T	A	5: 107,507,787 (GRCm38)	C639S	possibly damaging	Het
Grk3	T	A	5: 112,969,269 (GRCm38)	I89L	possibly damaging	Het
Grm8	A	T	6: 28,125,853 (GRCm38)	D91E	probably benign	Het
Havcr1	C	A	11: 46,752,507 (GRCm38)	H85N	probably benign	Het
Il12rb1	G	A	8: 70,813,372 (GRCm38)		probably null	Het
Kif3a	A	G	11: 53,598,327 (GRCm38)	K117E	probably damaging	Het
Kitl	T	A	10: 100,087,438 (GRCm38)	F15L	probably benign	Het
Ktn1	T	G	14: 47,695,507 (GRCm38)	L706R	probably damaging	Het
Lipg	T	C	18: 74,948,047 (GRCm38)	Y321C	probably damaging	Het
Mapk8ip3	T	C	17: 24,903,059 (GRCm38)	D710G	probably benign	Het
Mb21d1	A	T	9: 78,435,556 (GRCm38)	S321R	probably damaging	Het
Mchr1	A	G	15: 81,235,820 (GRCm38)	N16S	probably benign	Het
Myadml2	A	T	11: 120,647,727 (GRCm38)	L94*	probably null	Het
Npr3	C	A	15: 11,848,563 (GRCm38)	M439I	probably benign	Het
Obscn	A	G	11: 59,003,648 (GRCm38)	I6677T	unknown	Het
Ogn	A	C	13: 49,621,044 (GRCm38)	D221A	probably benign	Het
Olfr889	T	C	9: 38,115,934 (GRCm38)	I46T	probably benign	Het
Pard3b	C	A	1: 62,637,894 (GRCm38)	Q1195K	probably damaging	Het
Pcsk4	T	C	10: 80,321,951 (GRCm38)	E608G	probably benign	Het
Pdlim1	T	C	19: 40,223,072 (GRCm38)	D259G	probably benign	Het
Per1	T	C	11: 69,103,627 (GRCm38)	S526P	probably damaging	Het
Pfkfb2	A	G	1: 130,706,472 (GRCm38)	V156A	probably damaging	Het
Ppp4r3a	A	T	12: 101,055,822 (GRCm38)	D307E	probably damaging	Het
Rims4	T	C	2: 163,879,122 (GRCm38)	S70G	probably damaging	Het
Rnf213	T	C	11: 119,441,839 (GRCm38)	F2625L	probably benign	Het
Sap130	T	C	18: 31,666,472 (GRCm38)	L334P	probably damaging	Het
Slc16a10	T	C	10: 40,076,800 (GRCm38)	I233V	probably benign	Het
Slc16a7	A	C	10: 125,230,922 (GRCm38)	F283V	possibly damaging	Het
Slc25a24	T	C	3: 109,136,270 (GRCm38)	M81T	probably benign	Het
Slc30a9	A	G	5: 67,326,921 (GRCm38)	R134G	probably damaging	Het
Slc35d3	G	T	10: 19,850,737 (GRCm38)	L96M	probably damaging	Het
Slc7a11	C	T	3: 50,381,896 (GRCm38)	G333D	probably damaging	Het
Stam	T	C	2: 14,141,828 (GRCm38)	S446P	probably benign	Het
Stk38	T	A	17: 28,979,232 (GRCm38)	N248I	possibly damaging	Het
Tle6	A	C	10: 81,595,385 (GRCm38)	S221A	probably benign	Het
Tmprss11b	G	A	5: 86,661,631 (GRCm38)	T334I	probably benign	Het
Tmprss11c	T	A	5: 86,289,260 (GRCm38)	M1L	possibly damaging	Het
Tpm1	T	C	9: 67,023,429 (GRCm38)	H262R	probably benign	Het
Tspan33	T	C	6: 29,711,082 (GRCm38)	S118P	possibly damaging	Het
Tyk2	A	G	9: 21,107,922 (GRCm38)	V1068A	probably damaging	Het
Ubr2	T	C	17: 46,972,951 (GRCm38)	I591V	probably benign	Het
Utp20	A	T	10: 88,764,737 (GRCm38)	Y38*	probably null	Het
Vmn1r217	A	T	13: 23,114,294 (GRCm38)	I146N	possibly damaging	Het
Zfp608	T	C	18: 54,898,054 (GRCm38)	Y938C	probably damaging	Het

Other mutations in Dnah11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00341:Dnah11	APN	12	118,198,745 (GRCm38)	missense	probably benign	0.28
IGL00422:Dnah11	APN	12	118,068,096 (GRCm38)	missense	probably damaging	1.00
IGL00436:Dnah11	APN	12	118,036,459 (GRCm38)	missense	possibly damaging	0.56
IGL00540:Dnah11	APN	12	118,186,922 (GRCm38)	missense	probably benign	0.01
IGL00687:Dnah11	APN	12	117,922,004 (GRCm38)	splice site	probably benign
IGL00833:Dnah11	APN	12	118,179,580 (GRCm38)	missense	probably damaging	1.00
IGL00906:Dnah11	APN	12	117,911,202 (GRCm38)	missense	probably damaging	1.00
IGL00952:Dnah11	APN	12	118,196,651 (GRCm38)	missense	possibly damaging	0.56
IGL01111:Dnah11	APN	12	118,142,934 (GRCm38)	splice site	probably benign
IGL01121:Dnah11	APN	12	118,050,695 (GRCm38)	missense	probably benign	0.02
IGL01143:Dnah11	APN	12	118,012,740 (GRCm38)	missense	probably damaging	1.00
IGL01359:Dnah11	APN	12	117,982,999 (GRCm38)	missense	probably damaging	0.99
IGL01372:Dnah11	APN	12	118,192,399 (GRCm38)	missense	probably damaging	1.00
IGL01410:Dnah11	APN	12	118,047,256 (GRCm38)	nonsense	probably null
IGL01418:Dnah11	APN	12	117,987,482 (GRCm38)	nonsense	probably null
IGL01444:Dnah11	APN	12	118,020,232 (GRCm38)	missense	possibly damaging	0.91
IGL01606:Dnah11	APN	12	117,983,032 (GRCm38)	missense	probably benign	0.15
IGL01645:Dnah11	APN	12	118,186,998 (GRCm38)	missense	possibly damaging	0.90
IGL01932:Dnah11	APN	12	118,192,270 (GRCm38)	splice site	probably benign
IGL02104:Dnah11	APN	12	118,192,390 (GRCm38)	missense	probably benign
IGL02151:Dnah11	APN	12	118,059,888 (GRCm38)	splice site	probably benign
IGL02189:Dnah11	APN	12	118,082,579 (GRCm38)	missense	probably benign	0.00
IGL02417:Dnah11	APN	12	118,057,180 (GRCm38)	missense	probably damaging	1.00
IGL02421:Dnah11	APN	12	118,186,902 (GRCm38)	missense	probably damaging	1.00
IGL02444:Dnah11	APN	12	117,975,873 (GRCm38)	splice site	probably benign
IGL02474:Dnah11	APN	12	118,027,445 (GRCm38)	splice site	probably null
IGL02526:Dnah11	APN	12	118,179,618 (GRCm38)	missense	possibly damaging	0.70
IGL02887:Dnah11	APN	12	117,911,040 (GRCm38)	missense	probably damaging	1.00
IGL03011:Dnah11	APN	12	118,012,377 (GRCm38)	missense	probably benign	0.08
IGL03061:Dnah11	APN	12	117,903,121 (GRCm38)	missense	probably damaging	1.00
IGL03182:Dnah11	APN	12	118,030,291 (GRCm38)	missense	probably damaging	0.99
IGL03220:Dnah11	APN	12	118,105,985 (GRCm38)	missense	probably benign
IGL03238:Dnah11	APN	12	118,109,898 (GRCm38)	missense	probably damaging	1.00
IGL03493:Dnah11	APN	12	118,012,798 (GRCm38)	missense	probably benign	0.00
P0045:Dnah11	UTSW	12	118,030,327 (GRCm38)	missense	probably benign
R0009:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R0066:Dnah11	UTSW	12	118,126,886 (GRCm38)	missense	probably benign	0.05
R0172:Dnah11	UTSW	12	117,987,453 (GRCm38)	missense	probably damaging	1.00
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0206:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0208:Dnah11	UTSW	12	118,043,774 (GRCm38)	missense	probably damaging	0.98
R0230:Dnah11	UTSW	12	117,983,056 (GRCm38)	nonsense	probably null
R0270:Dnah11	UTSW	12	118,041,013 (GRCm38)	missense	probably damaging	1.00
R0311:Dnah11	UTSW	12	118,127,133 (GRCm38)	missense	probably benign	0.03
R0325:Dnah11	UTSW	12	118,012,339 (GRCm38)	missense	probably benign
R0370:Dnah11	UTSW	12	117,995,227 (GRCm38)	missense	probably benign
R0416:Dnah11	UTSW	12	117,911,058 (GRCm38)	missense	probably damaging	1.00
R0505:Dnah11	UTSW	12	118,106,510 (GRCm38)	missense	probably damaging	1.00
R0540:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0554:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably benign	0.01
R0607:Dnah11	UTSW	12	118,082,511 (GRCm38)	missense	probably damaging	1.00
R0620:Dnah11	UTSW	12	117,987,469 (GRCm38)	missense	probably damaging	1.00
R0635:Dnah11	UTSW	12	118,007,996 (GRCm38)	missense	probably damaging	1.00
R0755:Dnah11	UTSW	12	118,198,625 (GRCm38)	missense	probably benign	0.17
R0755:Dnah11	UTSW	12	117,954,829 (GRCm38)	missense	possibly damaging	0.95
R0789:Dnah11	UTSW	12	117,911,232 (GRCm38)	missense	probably damaging	1.00
R0833:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0835:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R0836:Dnah11	UTSW	12	118,196,662 (GRCm38)	missense	probably benign	0.01
R0846:Dnah11	UTSW	12	117,933,850 (GRCm38)	missense	probably damaging	0.97
R0865:Dnah11	UTSW	12	118,190,844 (GRCm38)	nonsense	probably null
R0928:Dnah11	UTSW	12	118,045,562 (GRCm38)	missense	probably damaging	1.00
R0939:Dnah11	UTSW	12	118,060,407 (GRCm38)	missense	probably damaging	1.00
R1203:Dnah11	UTSW	12	117,933,812 (GRCm38)	missense	possibly damaging	0.81
R1394:Dnah11	UTSW	12	117,972,364 (GRCm38)	missense	possibly damaging	0.75
R1398:Dnah11	UTSW	12	118,057,106 (GRCm38)	nonsense	probably null
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1465:Dnah11	UTSW	12	118,038,695 (GRCm38)	missense	probably damaging	1.00
R1500:Dnah11	UTSW	12	118,012,829 (GRCm38)	splice site	probably null
R1535:Dnah11	UTSW	12	118,018,730 (GRCm38)	missense	probably damaging	1.00
R1539:Dnah11	UTSW	12	117,931,256 (GRCm38)	missense	probably benign	0.01
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1574:Dnah11	UTSW	12	118,060,317 (GRCm38)	missense	probably damaging	1.00
R1615:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R1618:Dnah11	UTSW	12	118,015,465 (GRCm38)	missense	probably damaging	0.98
R1638:Dnah11	UTSW	12	118,015,419 (GRCm38)	missense	possibly damaging	0.81
R1659:Dnah11	UTSW	12	118,120,724 (GRCm38)	missense	possibly damaging	0.94
R1671:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1678:Dnah11	UTSW	12	117,933,845 (GRCm38)	missense	possibly damaging	0.50
R1699:Dnah11	UTSW	12	118,190,868 (GRCm38)	missense	probably damaging	1.00
R1712:Dnah11	UTSW	12	118,196,644 (GRCm38)	missense	probably benign	0.32
R1728:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1729:Dnah11	UTSW	12	117,916,931 (GRCm38)	missense	probably damaging	1.00
R1764:Dnah11	UTSW	12	118,190,825 (GRCm38)	missense	probably benign	0.31
R1780:Dnah11	UTSW	12	118,027,558 (GRCm38)	missense	probably damaging	1.00
R1789:Dnah11	UTSW	12	118,038,780 (GRCm38)	missense	probably damaging	0.99
R1800:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1863:Dnah11	UTSW	12	118,063,852 (GRCm38)	missense	possibly damaging	0.92
R1892:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R1907:Dnah11	UTSW	12	118,127,556 (GRCm38)	missense	possibly damaging	0.66
R1964:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R1967:Dnah11	UTSW	12	117,916,788 (GRCm38)	missense	probably damaging	1.00
R1997:Dnah11	UTSW	12	118,082,468 (GRCm38)	missense	possibly damaging	0.64
R2086:Dnah11	UTSW	12	118,113,871 (GRCm38)	missense	possibly damaging	0.82
R2092:Dnah11	UTSW	12	118,012,716 (GRCm38)	missense	possibly damaging	0.50
R2108:Dnah11	UTSW	12	118,020,353 (GRCm38)	missense	probably damaging	1.00
R2140:Dnah11	UTSW	12	118,008,810 (GRCm38)	missense	probably benign	0.01
R2261:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2261:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2262:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2262:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2263:Dnah11	UTSW	12	117,966,639 (GRCm38)	missense	probably damaging	0.99
R2263:Dnah11	UTSW	12	117,880,025 (GRCm38)	missense	probably benign	0.06
R2328:Dnah11	UTSW	12	117,886,686 (GRCm38)	missense	probably damaging	0.98
R2352:Dnah11	UTSW	12	117,928,330 (GRCm38)	missense	probably damaging	1.00
R2410:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R2885:Dnah11	UTSW	12	117,987,427 (GRCm38)	nonsense	probably null
R3499:Dnah11	UTSW	12	117,911,023 (GRCm38)	missense	probably damaging	1.00
R3741:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3742:Dnah11	UTSW	12	118,131,341 (GRCm38)	missense	probably benign	0.05
R3779:Dnah11	UTSW	12	118,130,713 (GRCm38)	splice site	probably benign
R3785:Dnah11	UTSW	12	118,017,602 (GRCm38)	missense	probably damaging	1.00
R3883:Dnah11	UTSW	12	117,978,453 (GRCm38)	splice site	probably benign
R4014:Dnah11	UTSW	12	117,974,914 (GRCm38)	missense	probably benign	0.16
R4043:Dnah11	UTSW	12	117,879,943 (GRCm38)	missense	probably damaging	1.00
R4072:Dnah11	UTSW	12	118,106,492 (GRCm38)	missense	probably damaging	1.00
R4073:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4074:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4076:Dnah11	UTSW	12	118,045,678 (GRCm38)	missense	probably benign	0.01
R4201:Dnah11	UTSW	12	117,966,659 (GRCm38)	missense	possibly damaging	0.63
R4224:Dnah11	UTSW	12	118,130,892 (GRCm38)	missense	probably benign	0.06
R4233:Dnah11	UTSW	12	117,916,791 (GRCm38)	missense	probably damaging	1.00
R4358:Dnah11	UTSW	12	118,125,843 (GRCm38)	nonsense	probably null
R4430:Dnah11	UTSW	12	117,983,011 (GRCm38)	missense	probably benign	0.26
R4465:Dnah11	UTSW	12	117,987,451 (GRCm38)	missense	probably benign	0.09
R4489:Dnah11	UTSW	12	117,916,896 (GRCm38)	missense	probably benign	0.31
R4572:Dnah11	UTSW	12	118,010,125 (GRCm38)	missense	probably benign	0.00
R4574:Dnah11	UTSW	12	118,012,255 (GRCm38)	critical splice donor site	probably null
R4657:Dnah11	UTSW	12	118,192,427 (GRCm38)	missense	probably benign	0.02
R4709:Dnah11	UTSW	12	118,018,760 (GRCm38)	missense	probably benign	0.26
R4740:Dnah11	UTSW	12	118,120,544 (GRCm38)	missense	probably benign	0.28
R4803:Dnah11	UTSW	12	118,127,608 (GRCm38)	missense	possibly damaging	0.50
R4896:Dnah11	UTSW	12	117,995,200 (GRCm38)	missense	probably damaging	1.00
R4908:Dnah11	UTSW	12	118,126,883 (GRCm38)	missense	probably benign	0.37
R5018:Dnah11	UTSW	12	118,130,728 (GRCm38)	missense	probably benign	0.00
R5071:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5074:Dnah11	UTSW	12	118,082,453 (GRCm38)	nonsense	probably null
R5080:Dnah11	UTSW	12	118,198,830 (GRCm38)	start codon destroyed	probably null	0.01
R5097:Dnah11	UTSW	12	118,017,700 (GRCm38)	missense	probably damaging	1.00
R5131:Dnah11	UTSW	12	117,954,751 (GRCm38)	missense	probably damaging	1.00
R5215:Dnah11	UTSW	12	118,157,361 (GRCm38)	missense	probably benign	0.09
R5252:Dnah11	UTSW	12	118,125,941 (GRCm38)	missense	probably damaging	1.00
R5296:Dnah11	UTSW	12	117,883,416 (GRCm38)	missense	probably damaging	1.00
R5308:Dnah11	UTSW	12	118,085,680 (GRCm38)	missense	possibly damaging	0.60
R5368:Dnah11	UTSW	12	117,954,893 (GRCm38)	missense	probably damaging	1.00
R5383:Dnah11	UTSW	12	118,085,697 (GRCm38)	missense	probably damaging	0.99
R5499:Dnah11	UTSW	12	118,106,474 (GRCm38)	missense	possibly damaging	0.53
R5503:Dnah11	UTSW	12	117,880,451 (GRCm38)	critical splice donor site	probably null
R5546:Dnah11	UTSW	12	117,975,848 (GRCm38)	missense	possibly damaging	0.83
R5578:Dnah11	UTSW	12	118,018,802 (GRCm38)	missense	probably damaging	0.99
R5657:Dnah11	UTSW	12	117,883,617 (GRCm38)	missense	probably damaging	1.00
R5702:Dnah11	UTSW	12	118,113,907 (GRCm38)	missense	probably benign	0.04
R5706:Dnah11	UTSW	12	118,023,935 (GRCm38)	missense	probably damaging	1.00
R5727:Dnah11	UTSW	12	118,127,106 (GRCm38)	missense	probably damaging	1.00
R5737:Dnah11	UTSW	12	118,192,390 (GRCm38)	missense	probably benign
R5884:Dnah11	UTSW	12	118,177,534 (GRCm38)	missense	probably benign	0.00
R5900:Dnah11	UTSW	12	118,082,431 (GRCm38)	splice site	probably null
R5905:Dnah11	UTSW	12	117,954,924 (GRCm38)	missense	probably damaging	1.00
R5928:Dnah11	UTSW	12	117,914,636 (GRCm38)	splice site	probably null
R5973:Dnah11	UTSW	12	118,110,952 (GRCm38)	missense	probably benign	0.02
R6024:Dnah11	UTSW	12	118,030,272 (GRCm38)	missense	probably benign	0.34
R6056:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign	0.03
R6075:Dnah11	UTSW	12	118,104,851 (GRCm38)	missense	probably damaging	1.00
R6092:Dnah11	UTSW	12	117,928,456 (GRCm38)	missense	probably benign
R6191:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R6197:Dnah11	UTSW	12	118,179,747 (GRCm38)	missense	probably benign	0.03
R6262:Dnah11	UTSW	12	117,931,178 (GRCm38)	missense	probably damaging	0.98
R6321:Dnah11	UTSW	12	118,142,292 (GRCm38)	missense	possibly damaging	0.56
R6454:Dnah11	UTSW	12	117,916,855 (GRCm38)	missense	probably benign	0.01
R6614:Dnah11	UTSW	12	117,886,676 (GRCm38)	missense	possibly damaging	0.72
R6694:Dnah11	UTSW	12	118,186,882 (GRCm38)	splice site	probably null
R6712:Dnah11	UTSW	12	118,050,722 (GRCm38)	missense	probably damaging	1.00
R6720:Dnah11	UTSW	12	118,045,646 (GRCm38)	missense	probably damaging	1.00
R6742:Dnah11	UTSW	12	118,113,894 (GRCm38)	missense	possibly damaging	0.82
R6806:Dnah11	UTSW	12	117,987,676 (GRCm38)	splice site	probably null
R6895:Dnah11	UTSW	12	117,995,191 (GRCm38)	missense	probably damaging	0.99
R6939:Dnah11	UTSW	12	118,106,562 (GRCm38)	missense	probably damaging	1.00
R6940:Dnah11	UTSW	12	118,198,768 (GRCm38)	missense	probably benign
R6945:Dnah11	UTSW	12	118,060,310 (GRCm38)	missense	probably damaging	1.00
R6958:Dnah11	UTSW	12	117,933,809 (GRCm38)	missense	probably damaging	1.00
R6970:Dnah11	UTSW	12	118,108,944 (GRCm38)	missense	probably benign	0.00
R6976:Dnah11	UTSW	12	118,198,643 (GRCm38)	missense	probably benign	0.16
R7000:Dnah11	UTSW	12	118,017,661 (GRCm38)	missense	probably damaging	1.00
R7011:Dnah11	UTSW	12	117,922,018 (GRCm38)	frame shift	probably null
R7101:Dnah11	UTSW	12	118,068,145 (GRCm38)	missense	probably benign
R7106:Dnah11	UTSW	12	117,961,149 (GRCm38)	missense	probably benign	0.15
R7203:Dnah11	UTSW	12	118,045,522 (GRCm38)	missense	possibly damaging	0.90
R7219:Dnah11	UTSW	12	118,126,889 (GRCm38)	missense	probably benign	0.00
R7219:Dnah11	UTSW	12	118,041,095 (GRCm38)	missense	possibly damaging	0.95
R7308:Dnah11	UTSW	12	117,995,275 (GRCm38)	missense	probably damaging	1.00
R7361:Dnah11	UTSW	12	118,018,742 (GRCm38)	missense	probably damaging	1.00
R7367:Dnah11	UTSW	12	117,987,442 (GRCm38)	missense	possibly damaging	0.59
R7399:Dnah11	UTSW	12	118,125,785 (GRCm38)	missense	probably damaging	1.00
R7399:Dnah11	UTSW	12	118,027,477 (GRCm38)	missense	probably benign	0.00
R7404:Dnah11	UTSW	12	118,104,808 (GRCm38)	missense	probably benign	0.36
R7473:Dnah11	UTSW	12	117,903,176 (GRCm38)	missense	probably benign	0.19
R7545:Dnah11	UTSW	12	117,931,204 (GRCm38)	missense	probably damaging	1.00
R7608:Dnah11	UTSW	12	118,140,770 (GRCm38)	splice site	probably null
R7625:Dnah11	UTSW	12	118,196,642 (GRCm38)	missense	probably benign
R7761:Dnah11	UTSW	12	118,023,913 (GRCm38)	missense	probably damaging	1.00
R7879:Dnah11	UTSW	12	118,041,009 (GRCm38)	missense	probably damaging	1.00
R7881:Dnah11	UTSW	12	117,987,502 (GRCm38)	missense	probably benign	0.04
R7904:Dnah11	UTSW	12	117,903,268 (GRCm38)	missense	possibly damaging	0.72
R8100:Dnah11	UTSW	12	117,966,633 (GRCm38)	missense	probably damaging	0.99
R8179:Dnah11	UTSW	12	117,878,549 (GRCm38)	missense	possibly damaging	0.90
R8192:Dnah11	UTSW	12	118,012,446 (GRCm38)	missense	probably benign
R8254:Dnah11	UTSW	12	117,878,524 (GRCm38)	missense	possibly damaging	0.89
R8268:Dnah11	UTSW	12	118,027,508 (GRCm38)	nonsense	probably null
R8272:Dnah11	UTSW	12	118,111,017 (GRCm38)	missense	probably benign	0.01
R8344:Dnah11	UTSW	12	118,085,731 (GRCm38)	missense	probably benign	0.00
R8515:Dnah11	UTSW	12	117,975,798 (GRCm38)	missense	probably damaging	1.00
R8528:Dnah11	UTSW	12	118,008,803 (GRCm38)	missense	probably damaging	0.96
R8557:Dnah11	UTSW	12	117,878,512 (GRCm38)	missense	probably benign
R8676:Dnah11	UTSW	12	118,190,804 (GRCm38)	missense	probably damaging	1.00
R8738:Dnah11	UTSW	12	118,085,649 (GRCm38)	critical splice donor site	probably null
R8773:Dnah11	UTSW	12	117,995,215 (GRCm38)	missense	possibly damaging	0.94
R8818:Dnah11	UTSW	12	117,911,029 (GRCm38)	missense	probably damaging	1.00
R8855:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8866:Dnah11	UTSW	12	118,192,372 (GRCm38)	missense	probably benign	0.03
R8881:Dnah11	UTSW	12	118,126,815 (GRCm38)	missense	probably benign	0.05
R8881:Dnah11	UTSW	12	118,113,912 (GRCm38)	missense	probably benign	0.00
R8920:Dnah11	UTSW	12	118,113,939 (GRCm38)	missense	probably damaging	0.99
R8944:Dnah11	UTSW	12	118,127,646 (GRCm38)	missense	possibly damaging	0.63
R8945:Dnah11	UTSW	12	118,023,983 (GRCm38)	missense	probably benign	0.36
R8962:Dnah11	UTSW	12	117,954,895 (GRCm38)	missense	probably damaging	1.00
R8962:Dnah11	UTSW	12	117,952,538 (GRCm38)	missense	probably damaging	1.00
R9059:Dnah11	UTSW	12	118,130,843 (GRCm38)	missense	probably benign	0.00
R9155:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9162:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9164:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9171:Dnah11	UTSW	12	117,931,183 (GRCm38)	missense	probably damaging	0.99
R9186:Dnah11	UTSW	12	118,190,897 (GRCm38)	missense	probably benign
R9205:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9208:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9234:Dnah11	UTSW	12	117,987,360 (GRCm38)	missense	probably damaging	1.00
R9264:Dnah11	UTSW	12	118,027,527 (GRCm38)	missense	probably damaging	1.00
R9290:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9291:Dnah11	UTSW	12	118,027,516 (GRCm38)	missense	probably damaging	0.99
R9315:Dnah11	UTSW	12	118,179,606 (GRCm38)	missense	probably benign	0.11
R9353:Dnah11	UTSW	12	118,179,699 (GRCm38)	missense	probably benign	0.00
R9375:Dnah11	UTSW	12	117,920,968 (GRCm38)	missense	possibly damaging	0.67
R9392:Dnah11	UTSW	12	118,177,555 (GRCm38)	missense	probably benign	0.00
R9392:Dnah11	UTSW	12	118,047,320 (GRCm38)	nonsense	probably null
R9433:Dnah11	UTSW	12	118,012,272 (GRCm38)	missense	probably damaging	1.00
R9511:Dnah11	UTSW	12	117,914,617 (GRCm38)	missense	probably damaging	1.00
R9526:Dnah11	UTSW	12	118,186,976 (GRCm38)	missense	probably damaging	0.98
R9566:Dnah11	UTSW	12	117,974,993 (GRCm38)	missense	possibly damaging	0.69
R9673:Dnah11	UTSW	12	118,018,778 (GRCm38)	missense	possibly damaging	0.91
R9705:Dnah11	UTSW	12	118,131,035 (GRCm38)	missense	probably damaging	1.00
R9716:Dnah11	UTSW	12	118,060,413 (GRCm38)	missense	probably damaging	0.99
R9746:Dnah11	UTSW	12	117,878,576 (GRCm38)	nonsense	probably null
R9764:Dnah11	UTSW	12	117,920,969 (GRCm38)	missense	probably benign	0.05
RF023:Dnah11	UTSW	12	117,954,850 (GRCm38)	missense	probably damaging	1.00
RF047:Dnah11	UTSW	12	118,010,083 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,895,012 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnah11	UTSW	12	117,982,969 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah11	UTSW	12	118,130,799 (GRCm38)	missense	probably damaging	0.97
Z1176:Dnah11	UTSW	12	118,127,119 (GRCm38)	missense	probably benign	0.00
Z1176:Dnah11	UTSW	12	117,931,177 (GRCm38)	missense	possibly damaging	0.81

Predicted Primers

PCR Primer
(F):5'- GCACCAACCTACAGTAGCTGGAAG -3'
(R):5'- TCTGCAACTCGAACAGACCATGAAG -3'

Sequencing Primer
(F):5'- CAGATCGACTGGTACTCAGG -3'
(R):5'- CATGAAGGACACAGTGCGTC -3'

Posted On

2014-04-13