Incidental Mutation 'R1542:Mmrn1'
| ID |
171808 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mmrn1
|
| Ensembl Gene |
ENSMUSG00000054641 |
| Gene Name |
multimerin 1 |
| Synonyms |
4921530G03Rik, Emilin4 |
| MMRRC Submission |
039581-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1542 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
60924976-60989378 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 60945118 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 186
(S186R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000145156
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000129603]
[ENSMUST00000204333]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000129603
AA Change: S186R
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000119609
Gene: ENSMUSG00000054641
AA Change: S186R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
3.3e-12 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1026 |
1059 |
1.62e-5 |
SMART |
|
C1Q
|
1076 |
1210 |
6.74e-49 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145763
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000204333
AA Change: S186R
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000145156
Gene: ENSMUSG00000054641
AA Change: S186R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
7.7e-13 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1025 |
1058 |
1.62e-5 |
SMART |
|
C1Q
|
1075 |
1209 |
6.74e-49 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
A |
G |
3: 124,414,406 (GRCm38) |
M208T |
possibly damaging |
Het |
| Acsbg2 |
T |
A |
17: 56,849,791 (GRCm38) |
I416F |
probably damaging |
Het |
| Adam6b |
G |
A |
12: 113,490,939 (GRCm38) |
D459N |
possibly damaging |
Het |
| Adprh |
A |
T |
16: 38,445,924 (GRCm38) |
D285E |
probably damaging |
Het |
| Aggf1 |
A |
T |
13: 95,370,942 (GRCm38) |
C112S |
probably benign |
Het |
| Als2cl |
T |
C |
9: 110,894,034 (GRCm38) |
V602A |
probably benign |
Het |
| Angptl2 |
G |
T |
2: 33,228,885 (GRCm38) |
V224F |
probably benign |
Het |
| Ap3b2 |
A |
T |
7: 81,478,077 (GRCm38) |
|
probably null |
Het |
| Aqp2 |
A |
C |
15: 99,583,842 (GRCm38) |
I206L |
probably benign |
Het |
| Asap2 |
A |
G |
12: 21,265,997 (GRCm38) |
D930G |
probably damaging |
Het |
| Cacna1e |
T |
A |
1: 154,477,779 (GRCm38) |
M682L |
probably benign |
Het |
| Ccdc18 |
A |
G |
5: 108,212,188 (GRCm38) |
N1146S |
probably benign |
Het |
| Ccr4 |
G |
A |
9: 114,492,005 (GRCm38) |
H331Y |
probably benign |
Het |
| Cd33 |
A |
G |
7: 43,532,106 (GRCm38) |
L210P |
probably damaging |
Het |
| Cep85l |
T |
C |
10: 53,301,584 (GRCm38) |
E351G |
probably damaging |
Het |
| Cntn6 |
C |
A |
6: 104,848,100 (GRCm38) |
T867K |
probably damaging |
Het |
| Cpeb2 |
C |
T |
5: 43,285,875 (GRCm38) |
R970C |
probably damaging |
Het |
| Cul7 |
T |
A |
17: 46,663,190 (GRCm38) |
L1467H |
probably damaging |
Het |
| Dscaml1 |
T |
A |
9: 45,749,440 (GRCm38) |
I1693K |
possibly damaging |
Het |
| Ebf4 |
A |
T |
2: 130,365,498 (GRCm38) |
M621L |
probably benign |
Het |
| Elp4 |
G |
T |
2: 105,794,609 (GRCm38) |
T313N |
probably benign |
Het |
| Epas1 |
T |
A |
17: 86,824,490 (GRCm38) |
I373N |
possibly damaging |
Het |
| Etnk1 |
A |
T |
6: 143,180,641 (GRCm38) |
M71L |
probably benign |
Het |
| Fry |
C |
T |
5: 150,404,966 (GRCm38) |
T1257I |
probably benign |
Het |
| Gm21834 |
A |
G |
17: 57,741,951 (GRCm38) |
F90S |
possibly damaging |
Het |
| Gm8674 |
T |
A |
13: 49,900,003 (GRCm38) |
|
noncoding transcript |
Het |
| Gna11 |
T |
C |
10: 81,533,328 (GRCm38) |
T134A |
probably benign |
Het |
| Golga5 |
C |
T |
12: 102,474,720 (GRCm38) |
S238F |
probably damaging |
Het |
| Grin2a |
T |
A |
16: 9,579,203 (GRCm38) |
N1007Y |
probably damaging |
Het |
| Hist1h3e |
A |
G |
13: 23,562,164 (GRCm38) |
F68L |
probably damaging |
Het |
| Ifnar2 |
G |
A |
16: 91,399,265 (GRCm38) |
V253M |
possibly damaging |
Het |
| Insl5 |
A |
T |
4: 103,018,185 (GRCm38) |
S123T |
probably damaging |
Het |
| Itgb2 |
T |
C |
10: 77,559,486 (GRCm38) |
S474P |
probably benign |
Het |
| Kcnb2 |
A |
G |
1: 15,710,788 (GRCm38) |
H628R |
probably benign |
Het |
| L3mbtl2 |
G |
A |
15: 81,682,151 (GRCm38) |
D392N |
probably null |
Het |
| Lrp1b |
G |
T |
2: 41,123,712 (GRCm38) |
T1813K |
probably damaging |
Het |
| Map3k4 |
A |
G |
17: 12,235,906 (GRCm38) |
L1399P |
probably damaging |
Het |
| Mbtps1 |
A |
C |
8: 119,546,247 (GRCm38) |
|
probably null |
Het |
| Mettl25 |
A |
T |
10: 105,826,120 (GRCm38) |
S330T |
probably benign |
Het |
| Mical2 |
T |
C |
7: 112,309,468 (GRCm38) |
L211P |
probably damaging |
Het |
| Mob3b |
C |
A |
4: 35,084,046 (GRCm38) |
V48L |
possibly damaging |
Het |
| Mpp6 |
A |
G |
6: 50,198,326 (GRCm38) |
Y539C |
probably damaging |
Het |
| Napsa |
A |
T |
7: 44,581,689 (GRCm38) |
H114L |
probably damaging |
Het |
| Nsmce4a |
A |
T |
7: 130,545,893 (GRCm38) |
|
probably null |
Het |
| Nup62 |
A |
G |
7: 44,829,929 (GRCm38) |
K456R |
possibly damaging |
Het |
| Nwd2 |
T |
A |
5: 63,806,975 (GRCm38) |
W1301R |
probably damaging |
Het |
| Olfr1141 |
A |
G |
2: 87,753,318 (GRCm38) |
V225A |
probably damaging |
Het |
| Olfr118 |
A |
T |
17: 37,672,251 (GRCm38) |
E76V |
probably damaging |
Het |
| Olfr15 |
T |
A |
16: 3,839,832 (GRCm38) |
N286K |
probably damaging |
Het |
| Olfr364-ps1 |
T |
A |
2: 37,146,966 (GRCm38) |
S251R |
probably damaging |
Het |
| Oprm1 |
G |
T |
10: 6,788,960 (GRCm38) |
W29L |
probably damaging |
Het |
| Pcnt |
T |
G |
10: 76,389,387 (GRCm38) |
N1761T |
probably benign |
Het |
| Pcnt |
C |
T |
10: 76,401,386 (GRCm38) |
M1355I |
probably benign |
Het |
| Pde11a |
A |
T |
2: 76,046,855 (GRCm38) |
S757T |
probably benign |
Het |
| Pde6a |
T |
A |
18: 61,257,045 (GRCm38) |
I490N |
possibly damaging |
Het |
| Pgap1 |
A |
G |
1: 54,492,090 (GRCm38) |
V742A |
probably benign |
Het |
| Pik3c2b |
T |
C |
1: 133,090,034 (GRCm38) |
L915P |
probably damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,874,179 (GRCm38) |
C1129R |
possibly damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,528,191 (GRCm38) |
H1551L |
probably benign |
Het |
| Plxnb2 |
C |
T |
15: 89,165,921 (GRCm38) |
C491Y |
probably damaging |
Het |
| Ppt1 |
C |
A |
4: 122,857,609 (GRCm38) |
H300N |
probably benign |
Het |
| Prpf3 |
T |
A |
3: 95,836,470 (GRCm38) |
Q457L |
probably benign |
Het |
| Ranbp17 |
C |
T |
11: 33,264,672 (GRCm38) |
V914I |
probably benign |
Het |
| Rasal2 |
T |
C |
1: 157,175,851 (GRCm38) |
I413V |
possibly damaging |
Het |
| Rb1cc1 |
G |
A |
1: 6,244,249 (GRCm38) |
V382I |
possibly damaging |
Het |
| Rere |
T |
A |
4: 150,615,942 (GRCm38) |
F1125I |
probably damaging |
Het |
| Rprd2 |
A |
T |
3: 95,765,676 (GRCm38) |
V805E |
possibly damaging |
Het |
| Sept10 |
T |
G |
10: 59,166,606 (GRCm38) |
E162A |
probably damaging |
Het |
| Sept12 |
G |
T |
16: 4,992,295 (GRCm38) |
D125E |
probably benign |
Het |
| Serpina6 |
A |
G |
12: 103,654,473 (GRCm38) |
Y6H |
probably benign |
Het |
| Serpinb3c |
T |
C |
1: 107,272,787 (GRCm38) |
M209V |
probably damaging |
Het |
| Slc2a7 |
A |
T |
4: 150,168,471 (GRCm38) |
T523S |
probably damaging |
Het |
| Smdt1 |
T |
C |
15: 82,346,175 (GRCm38) |
V31A |
possibly damaging |
Het |
| Snrnp48 |
T |
C |
13: 38,220,704 (GRCm38) |
I245T |
probably damaging |
Het |
| Spink2 |
G |
A |
5: 77,206,965 (GRCm38) |
T33I |
probably damaging |
Het |
| Sptan1 |
A |
G |
2: 30,027,127 (GRCm38) |
T2204A |
probably damaging |
Het |
| Synj2 |
A |
G |
17: 6,025,017 (GRCm38) |
D306G |
probably benign |
Het |
| Tas2r109 |
A |
G |
6: 132,980,910 (GRCm38) |
I19T |
possibly damaging |
Het |
| Tbk1 |
C |
T |
10: 121,559,935 (GRCm38) |
V418M |
probably benign |
Het |
| Tcerg1 |
A |
G |
18: 42,553,430 (GRCm38) |
E684G |
probably damaging |
Het |
| Tenm2 |
T |
C |
11: 36,300,220 (GRCm38) |
N308S |
probably damaging |
Het |
| Tfb2m |
A |
T |
1: 179,537,861 (GRCm38) |
|
probably null |
Het |
| Tmc1 |
T |
A |
19: 20,816,122 (GRCm38) |
L558F |
probably damaging |
Het |
| Tmprss5 |
T |
A |
9: 49,109,134 (GRCm38) |
I80N |
possibly damaging |
Het |
| Trappc2l |
G |
A |
8: 122,615,407 (GRCm38) |
V131M |
probably damaging |
Het |
| Trpm7 |
A |
C |
2: 126,822,599 (GRCm38) |
Y953* |
probably null |
Het |
| Ttn |
T |
C |
2: 76,753,515 (GRCm38) |
R22383G |
probably damaging |
Het |
| Ugt1a6b |
G |
A |
1: 88,107,261 (GRCm38) |
G107D |
probably benign |
Het |
| Vmn1r197 |
A |
T |
13: 22,328,350 (GRCm38) |
Y147F |
probably benign |
Het |
| Zfp507 |
A |
T |
7: 35,794,801 (GRCm38) |
N272K |
possibly damaging |
Het |
| Zfp526 |
G |
A |
7: 25,226,262 (GRCm38) |
E649K |
probably benign |
Het |
| Zswim6 |
G |
A |
13: 107,727,234 (GRCm38) |
|
noncoding transcript |
Het |
|
| Other mutations in Mmrn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00640:Mmrn1
|
APN |
6 |
60,977,513 (GRCm38) |
missense |
probably benign |
|
|
IGL00742:Mmrn1
|
APN |
6 |
60,958,120 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00917:Mmrn1
|
APN |
6 |
60,975,910 (GRCm38) |
nonsense |
probably null |
|
|
IGL01121:Mmrn1
|
APN |
6 |
60,975,944 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01393:Mmrn1
|
APN |
6 |
60,960,708 (GRCm38) |
splice site |
probably benign |
|
|
IGL01697:Mmrn1
|
APN |
6 |
60,976,493 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01737:Mmrn1
|
APN |
6 |
60,977,161 (GRCm38) |
missense |
probably benign |
|
|
IGL01944:Mmrn1
|
APN |
6 |
60,971,183 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01987:Mmrn1
|
APN |
6 |
60,944,573 (GRCm38) |
missense |
probably benign |
0.31 |
|
IGL02005:Mmrn1
|
APN |
6 |
60,960,744 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02190:Mmrn1
|
APN |
6 |
60,987,193 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02335:Mmrn1
|
APN |
6 |
60,977,147 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL02421:Mmrn1
|
APN |
6 |
60,944,822 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02530:Mmrn1
|
APN |
6 |
60,958,176 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
IGL02709:Mmrn1
|
APN |
6 |
60,973,046 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03139:Mmrn1
|
APN |
6 |
60,976,340 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03228:Mmrn1
|
APN |
6 |
60,944,892 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03272:Mmrn1
|
APN |
6 |
60,988,435 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03410:Mmrn1
|
APN |
6 |
60,975,835 (GRCm38) |
missense |
probably benign |
0.36 |
|
H8562:Mmrn1
|
UTSW |
6 |
60,958,180 (GRCm38) |
missense |
probably damaging |
0.98 |
|
K2124:Mmrn1
|
UTSW |
6 |
60,976,033 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0145:Mmrn1
|
UTSW |
6 |
60,973,010 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:Mmrn1
|
UTSW |
6 |
60,975,815 (GRCm38) |
splice site |
probably benign |
|
|
R0352:Mmrn1
|
UTSW |
6 |
60,944,971 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0400:Mmrn1
|
UTSW |
6 |
60,977,115 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0538:Mmrn1
|
UTSW |
6 |
60,976,469 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0907:Mmrn1
|
UTSW |
6 |
60,973,119 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1117:Mmrn1
|
UTSW |
6 |
60,976,325 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R1383:Mmrn1
|
UTSW |
6 |
60,976,322 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1591:Mmrn1
|
UTSW |
6 |
60,944,771 (GRCm38) |
nonsense |
probably null |
|
|
R1599:Mmrn1
|
UTSW |
6 |
60,945,037 (GRCm38) |
missense |
probably benign |
|
|
R1733:Mmrn1
|
UTSW |
6 |
60,977,101 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2005:Mmrn1
|
UTSW |
6 |
60,976,084 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R2056:Mmrn1
|
UTSW |
6 |
60,944,805 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2144:Mmrn1
|
UTSW |
6 |
60,945,075 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R2299:Mmrn1
|
UTSW |
6 |
60,976,441 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3836:Mmrn1
|
UTSW |
6 |
60,944,847 (GRCm38) |
missense |
probably benign |
|
|
R3837:Mmrn1
|
UTSW |
6 |
60,944,847 (GRCm38) |
missense |
probably benign |
|
|
R4206:Mmrn1
|
UTSW |
6 |
60,958,180 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4414:Mmrn1
|
UTSW |
6 |
60,944,586 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4590:Mmrn1
|
UTSW |
6 |
60,960,813 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4707:Mmrn1
|
UTSW |
6 |
60,988,473 (GRCm38) |
missense |
probably benign |
0.12 |
|
R4820:Mmrn1
|
UTSW |
6 |
60,973,043 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4880:Mmrn1
|
UTSW |
6 |
60,976,439 (GRCm38) |
missense |
probably benign |
0.15 |
|
R5166:Mmrn1
|
UTSW |
6 |
60,976,490 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5324:Mmrn1
|
UTSW |
6 |
60,976,586 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5887:Mmrn1
|
UTSW |
6 |
60,987,074 (GRCm38) |
missense |
probably benign |
|
|
R5917:Mmrn1
|
UTSW |
6 |
60,973,150 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6108:Mmrn1
|
UTSW |
6 |
60,975,976 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R6539:Mmrn1
|
UTSW |
6 |
60,987,184 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6996:Mmrn1
|
UTSW |
6 |
60,977,383 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7064:Mmrn1
|
UTSW |
6 |
60,988,540 (GRCm38) |
nonsense |
probably null |
|
|
R7073:Mmrn1
|
UTSW |
6 |
60,988,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7213:Mmrn1
|
UTSW |
6 |
60,944,543 (GRCm38) |
start gained |
probably benign |
|
|
R7256:Mmrn1
|
UTSW |
6 |
60,976,114 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7324:Mmrn1
|
UTSW |
6 |
60,944,933 (GRCm38) |
nonsense |
probably null |
|
|
R7350:Mmrn1
|
UTSW |
6 |
60,976,336 (GRCm38) |
nonsense |
probably null |
|
|
R7388:Mmrn1
|
UTSW |
6 |
60,976,252 (GRCm38) |
missense |
probably benign |
0.43 |
|
R7652:Mmrn1
|
UTSW |
6 |
60,977,506 (GRCm38) |
missense |
probably benign |
0.14 |
|
R7664:Mmrn1
|
UTSW |
6 |
60,976,705 (GRCm38) |
missense |
probably benign |
0.44 |
|
R7810:Mmrn1
|
UTSW |
6 |
60,976,325 (GRCm38) |
missense |
probably benign |
0.18 |
|
R7832:Mmrn1
|
UTSW |
6 |
60,987,060 (GRCm38) |
splice site |
probably null |
|
|
R7979:Mmrn1
|
UTSW |
6 |
60,975,977 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8071:Mmrn1
|
UTSW |
6 |
60,944,524 (GRCm38) |
start gained |
probably benign |
|
|
R8130:Mmrn1
|
UTSW |
6 |
60,960,723 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8277:Mmrn1
|
UTSW |
6 |
60,977,236 (GRCm38) |
missense |
probably benign |
0.19 |
|
R8353:Mmrn1
|
UTSW |
6 |
60,988,377 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8453:Mmrn1
|
UTSW |
6 |
60,988,377 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8472:Mmrn1
|
UTSW |
6 |
60,988,396 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8758:Mmrn1
|
UTSW |
6 |
60,987,209 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R8803:Mmrn1
|
UTSW |
6 |
60,988,287 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8879:Mmrn1
|
UTSW |
6 |
60,976,529 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8907:Mmrn1
|
UTSW |
6 |
60,976,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8983:Mmrn1
|
UTSW |
6 |
60,976,058 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9200:Mmrn1
|
UTSW |
6 |
60,976,876 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9287:Mmrn1
|
UTSW |
6 |
60,975,955 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9387:Mmrn1
|
UTSW |
6 |
60,958,192 (GRCm38) |
nonsense |
probably null |
|
|
R9612:Mmrn1
|
UTSW |
6 |
60,976,424 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9674:Mmrn1
|
UTSW |
6 |
60,971,088 (GRCm38) |
nonsense |
probably null |
|
|
X0026:Mmrn1
|
UTSW |
6 |
60,976,013 (GRCm38) |
missense |
probably benign |
0.09 |
|
Z1176:Mmrn1
|
UTSW |
6 |
60,945,034 (GRCm38) |
missense |
probably benign |
0.37 |
|
Z1177:Mmrn1
|
UTSW |
6 |
60,987,098 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAACTGTCATGCTTGCTAATGCCAC -3'
(R):5'- TGCTACAACAATGCAAACTGCTGTC -3'
Sequencing Primer
(F):5'- GCCACGTTGAAATTCCTTCAGAG -3'
(R):5'- ATGCTCCTGACAAGTGTGAC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation