Incidental Mutation 'R1542:Mical2'
| ID |
171822 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
039581-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R1542 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 111908675 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 211
(L211P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051163
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037991
AA Change: L211P
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: L211P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000050149
AA Change: L211P
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
AA Change: L211P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000106647
|
| SMART Domains |
Protein: ENSMUSP00000102258
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NAD_binding_7
|
83 |
172 |
5.9e-7 |
PFAM |
|
Pfam:FAD_binding_3
|
86 |
144 |
5.9e-9 |
PFAM |
|
Pfam:Pyr_redox
|
88 |
126 |
3.4e-6 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
4.8e-7 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
245 |
2.9e-7 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000106648
|
| SMART Domains |
Protein: ENSMUSP00000102259
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
9.5e-9 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.3e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
263 |
1e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
1.71e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
A |
G |
3: 124,208,055 (GRCm39) |
M208T |
possibly damaging |
Het |
| Acsbg2 |
T |
A |
17: 57,156,791 (GRCm39) |
I416F |
probably damaging |
Het |
| Adam6b |
G |
A |
12: 113,454,559 (GRCm39) |
D459N |
possibly damaging |
Het |
| Adprh |
A |
T |
16: 38,266,286 (GRCm39) |
D285E |
probably damaging |
Het |
| Aggf1 |
A |
T |
13: 95,507,450 (GRCm39) |
C112S |
probably benign |
Het |
| Als2cl |
T |
C |
9: 110,723,102 (GRCm39) |
V602A |
probably benign |
Het |
| Angptl2 |
G |
T |
2: 33,118,897 (GRCm39) |
V224F |
probably benign |
Het |
| Ap3b2 |
A |
T |
7: 81,127,825 (GRCm39) |
|
probably null |
Het |
| Aqp2 |
A |
C |
15: 99,481,723 (GRCm39) |
I206L |
probably benign |
Het |
| Asap2 |
A |
G |
12: 21,315,998 (GRCm39) |
D930G |
probably damaging |
Het |
| Cacna1e |
T |
A |
1: 154,353,525 (GRCm39) |
M682L |
probably benign |
Het |
| Ccdc18 |
A |
G |
5: 108,360,054 (GRCm39) |
N1146S |
probably benign |
Het |
| Ccr4 |
G |
A |
9: 114,321,073 (GRCm39) |
H331Y |
probably benign |
Het |
| Cd33 |
A |
G |
7: 43,181,530 (GRCm39) |
L210P |
probably damaging |
Het |
| Cep85l |
T |
C |
10: 53,177,680 (GRCm39) |
E351G |
probably damaging |
Het |
| Cntn6 |
C |
A |
6: 104,825,061 (GRCm39) |
T867K |
probably damaging |
Het |
| Cpeb2 |
C |
T |
5: 43,443,218 (GRCm39) |
R970C |
probably damaging |
Het |
| Cul7 |
T |
A |
17: 46,974,116 (GRCm39) |
L1467H |
probably damaging |
Het |
| Dscaml1 |
T |
A |
9: 45,660,738 (GRCm39) |
I1693K |
possibly damaging |
Het |
| Ebf4 |
A |
T |
2: 130,207,418 (GRCm39) |
M621L |
probably benign |
Het |
| Elp4 |
G |
T |
2: 105,624,954 (GRCm39) |
T313N |
probably benign |
Het |
| Epas1 |
T |
A |
17: 87,131,918 (GRCm39) |
I373N |
possibly damaging |
Het |
| Etnk1 |
A |
T |
6: 143,126,367 (GRCm39) |
M71L |
probably benign |
Het |
| Fry |
C |
T |
5: 150,328,431 (GRCm39) |
T1257I |
probably benign |
Het |
| Gm21834 |
A |
G |
17: 58,048,946 (GRCm39) |
F90S |
possibly damaging |
Het |
| Gm8674 |
T |
A |
13: 50,054,039 (GRCm39) |
|
noncoding transcript |
Het |
| Gna11 |
T |
C |
10: 81,369,162 (GRCm39) |
T134A |
probably benign |
Het |
| Golga5 |
C |
T |
12: 102,440,979 (GRCm39) |
S238F |
probably damaging |
Het |
| Grin2a |
T |
A |
16: 9,397,067 (GRCm39) |
N1007Y |
probably damaging |
Het |
| H3c6 |
A |
G |
13: 23,746,338 (GRCm39) |
F68L |
probably damaging |
Het |
| Ifnar2 |
G |
A |
16: 91,196,153 (GRCm39) |
V253M |
possibly damaging |
Het |
| Insl5 |
A |
T |
4: 102,875,382 (GRCm39) |
S123T |
probably damaging |
Het |
| Itgb2 |
T |
C |
10: 77,395,320 (GRCm39) |
S474P |
probably benign |
Het |
| Kcnb2 |
A |
G |
1: 15,781,012 (GRCm39) |
H628R |
probably benign |
Het |
| L3mbtl2 |
G |
A |
15: 81,566,352 (GRCm39) |
D392N |
probably null |
Het |
| Lrp1b |
G |
T |
2: 41,013,724 (GRCm39) |
T1813K |
probably damaging |
Het |
| Map3k4 |
A |
G |
17: 12,454,793 (GRCm39) |
L1399P |
probably damaging |
Het |
| Mbtps1 |
A |
C |
8: 120,272,986 (GRCm39) |
|
probably null |
Het |
| Mettl25 |
A |
T |
10: 105,661,981 (GRCm39) |
S330T |
probably benign |
Het |
| Mmrn1 |
T |
A |
6: 60,922,102 (GRCm39) |
S186R |
probably damaging |
Het |
| Mob3b |
C |
A |
4: 35,084,046 (GRCm39) |
V48L |
possibly damaging |
Het |
| Napsa |
A |
T |
7: 44,231,113 (GRCm39) |
H114L |
probably damaging |
Het |
| Nsmce4a |
A |
T |
7: 130,147,623 (GRCm39) |
|
probably null |
Het |
| Nup62 |
A |
G |
7: 44,479,353 (GRCm39) |
K456R |
possibly damaging |
Het |
| Nwd2 |
T |
A |
5: 63,964,318 (GRCm39) |
W1301R |
probably damaging |
Het |
| Oprm1 |
G |
T |
10: 6,738,960 (GRCm39) |
W29L |
probably damaging |
Het |
| Or10al2 |
A |
T |
17: 37,983,142 (GRCm39) |
E76V |
probably damaging |
Het |
| Or1l4b |
T |
A |
2: 37,036,978 (GRCm39) |
S251R |
probably damaging |
Het |
| Or2c1 |
T |
A |
16: 3,657,696 (GRCm39) |
N286K |
probably damaging |
Het |
| Or5w17 |
A |
G |
2: 87,583,662 (GRCm39) |
V225A |
probably damaging |
Het |
| Pals2 |
A |
G |
6: 50,175,306 (GRCm39) |
Y539C |
probably damaging |
Het |
| Pcnt |
T |
G |
10: 76,225,221 (GRCm39) |
N1761T |
probably benign |
Het |
| Pcnt |
C |
T |
10: 76,237,220 (GRCm39) |
M1355I |
probably benign |
Het |
| Pde11a |
A |
T |
2: 75,877,199 (GRCm39) |
S757T |
probably benign |
Het |
| Pde6a |
T |
A |
18: 61,390,116 (GRCm39) |
I490N |
possibly damaging |
Het |
| Pgap1 |
A |
G |
1: 54,531,249 (GRCm39) |
V742A |
probably benign |
Het |
| Pik3c2b |
T |
C |
1: 133,017,772 (GRCm39) |
L915P |
probably damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,824,179 (GRCm39) |
C1129R |
possibly damaging |
Het |
| Pkhd1l1 |
A |
T |
15: 44,391,587 (GRCm39) |
H1551L |
probably benign |
Het |
| Plxnb2 |
C |
T |
15: 89,050,124 (GRCm39) |
C491Y |
probably damaging |
Het |
| Ppt1 |
C |
A |
4: 122,751,402 (GRCm39) |
H300N |
probably benign |
Het |
| Prpf3 |
T |
A |
3: 95,743,782 (GRCm39) |
Q457L |
probably benign |
Het |
| Ranbp17 |
C |
T |
11: 33,214,672 (GRCm39) |
V914I |
probably benign |
Het |
| Rasal2 |
T |
C |
1: 157,003,421 (GRCm39) |
I413V |
possibly damaging |
Het |
| Rb1cc1 |
G |
A |
1: 6,314,473 (GRCm39) |
V382I |
possibly damaging |
Het |
| Rere |
T |
A |
4: 150,700,399 (GRCm39) |
F1125I |
probably damaging |
Het |
| Rprd2 |
A |
T |
3: 95,672,988 (GRCm39) |
V805E |
possibly damaging |
Het |
| Septin10 |
T |
G |
10: 59,002,428 (GRCm39) |
E162A |
probably damaging |
Het |
| Septin12 |
G |
T |
16: 4,810,159 (GRCm39) |
D125E |
probably benign |
Het |
| Serpina6 |
A |
G |
12: 103,620,732 (GRCm39) |
Y6H |
probably benign |
Het |
| Serpinb3c |
T |
C |
1: 107,200,517 (GRCm39) |
M209V |
probably damaging |
Het |
| Slc2a7 |
A |
T |
4: 150,252,928 (GRCm39) |
T523S |
probably damaging |
Het |
| Smdt1 |
T |
C |
15: 82,230,376 (GRCm39) |
V31A |
possibly damaging |
Het |
| Snrnp48 |
T |
C |
13: 38,404,680 (GRCm39) |
I245T |
probably damaging |
Het |
| Spink2 |
G |
A |
5: 77,354,812 (GRCm39) |
T33I |
probably damaging |
Het |
| Sptan1 |
A |
G |
2: 29,917,139 (GRCm39) |
T2204A |
probably damaging |
Het |
| Synj2 |
A |
G |
17: 6,075,292 (GRCm39) |
D306G |
probably benign |
Het |
| Tas2r109 |
A |
G |
6: 132,957,873 (GRCm39) |
I19T |
possibly damaging |
Het |
| Tbk1 |
C |
T |
10: 121,395,840 (GRCm39) |
V418M |
probably benign |
Het |
| Tcerg1 |
A |
G |
18: 42,686,495 (GRCm39) |
E684G |
probably damaging |
Het |
| Tenm2 |
T |
C |
11: 36,191,047 (GRCm39) |
N308S |
probably damaging |
Het |
| Tfb2m |
A |
T |
1: 179,365,426 (GRCm39) |
|
probably null |
Het |
| Tmc1 |
T |
A |
19: 20,793,486 (GRCm39) |
L558F |
probably damaging |
Het |
| Tmprss5 |
T |
A |
9: 49,020,434 (GRCm39) |
I80N |
possibly damaging |
Het |
| Trappc2l |
G |
A |
8: 123,342,146 (GRCm39) |
V131M |
probably damaging |
Het |
| Trpm7 |
A |
C |
2: 126,664,519 (GRCm39) |
Y953* |
probably null |
Het |
| Ttn |
T |
C |
2: 76,583,859 (GRCm39) |
R22383G |
probably damaging |
Het |
| Ugt1a6b |
G |
A |
1: 88,034,983 (GRCm39) |
G107D |
probably benign |
Het |
| Vmn1r197 |
A |
T |
13: 22,512,520 (GRCm39) |
Y147F |
probably benign |
Het |
| Zfp507 |
A |
T |
7: 35,494,226 (GRCm39) |
N272K |
possibly damaging |
Het |
| Zfp526 |
G |
A |
7: 24,925,687 (GRCm39) |
E649K |
probably benign |
Het |
| Zswim6 |
G |
A |
13: 107,863,769 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGGGATGAGAAGCCATTGAGTTGG -3'
(R):5'- GGTGCTCTGAAAGGGTTCTGCTAC -3'
Sequencing Primer
(F):5'- ccattaaaaaccctccattgcc -3'
(R):5'- GAAAGGGTTCTGCTACCCATATTC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation