Incidental Mutation 'R1618:Sbno1'
| ID |
174425 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sbno1
|
| Ensembl Gene |
ENSMUSG00000038095 |
| Gene Name |
strawberry notch 1 |
| Synonyms |
9330180L10Rik, sno |
| MMRRC Submission |
039655-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1618 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
124506765-124564059 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 124542279 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 338
(Y338C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142481
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000065263]
[ENSMUST00000168651]
[ENSMUST00000196329]
[ENSMUST00000196644]
[ENSMUST00000196711]
[ENSMUST00000199004]
[ENSMUST00000199808]
[ENSMUST00000200474]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000065263
AA Change: Y338C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000066808
Gene: ENSMUSG00000038095
AA Change: Y338C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
254 |
559 |
3.6e-144 |
PFAM |
|
Pfam:ResIII
|
287 |
478 |
2.7e-8 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
3.6e-126 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000168651
AA Change: Y337C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000130860
Gene: ENSMUSG00000038095
AA Change: Y337C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
254 |
559 |
3.6e-144 |
PFAM |
|
Pfam:ResIII
|
287 |
478 |
2.7e-8 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
3.6e-126 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000196329
AA Change: Y303C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000143084
Gene: ENSMUSG00000038095
AA Change: Y303C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
182 |
199 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
217 |
525 |
1.4e-139 |
PFAM |
|
Pfam:ResIII
|
254 |
441 |
2.4e-8 |
PFAM |
|
low complexity region
|
598 |
614 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000196644
AA Change: Y338C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142827
Gene: ENSMUSG00000038095
AA Change: Y338C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
252 |
560 |
4.3e-136 |
PFAM |
|
Pfam:ResIII
|
289 |
476 |
1.8e-6 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196711
|
| SMART Domains |
Protein: ENSMUSP00000142980
Gene: ENSMUSG00000038095
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
182 |
199 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199004
|
| SMART Domains |
Protein: ENSMUSP00000143314
Gene: ENSMUSG00000038095
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000199808
AA Change: Y338C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142481
Gene: ENSMUSG00000038095
AA Change: Y338C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
252 |
560 |
6e-139 |
PFAM |
|
Pfam:ResIII
|
289 |
476 |
1.3e-7 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
4.6e-120 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000200474
AA Change: Y302C
PolyPhen 2
Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000143516
Gene: ENSMUSG00000038095
AA Change: Y302C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
181 |
198 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
218 |
523 |
2.3e-141 |
PFAM |
|
Pfam:ResIII
|
251 |
442 |
3.3e-7 |
PFAM |
|
low complexity region
|
597 |
613 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
755 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000200674
AA Change: Y89C
|
| Meta Mutation Damage Score |
0.9562 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.3%
- 20x: 89.1%
|
| Validation Efficiency |
96% (79/82) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930449E01Rik |
T |
C |
14: 105,736,380 (GRCm39) |
|
noncoding transcript |
Het |
| Abca8b |
A |
T |
11: 109,840,714 (GRCm39) |
|
probably benign |
Het |
| Akp3 |
G |
A |
1: 87,055,593 (GRCm39) |
G547R |
unknown |
Het |
| Anln |
A |
G |
9: 22,262,214 (GRCm39) |
|
probably null |
Het |
| Anpep |
T |
G |
7: 79,485,165 (GRCm39) |
Q607P |
probably benign |
Het |
| Arl13b |
A |
C |
16: 62,633,640 (GRCm39) |
|
probably null |
Het |
| Asxl3 |
T |
C |
18: 22,650,044 (GRCm39) |
S678P |
probably damaging |
Het |
| Atf6b |
C |
T |
17: 34,866,702 (GRCm39) |
Q58* |
probably null |
Het |
| Camsap3 |
A |
G |
8: 3,648,740 (GRCm39) |
T20A |
probably benign |
Het |
| Cfap46 |
T |
A |
7: 139,232,726 (GRCm39) |
M782L |
probably benign |
Het |
| Cngb3 |
T |
C |
4: 19,364,260 (GRCm39) |
S155P |
probably benign |
Het |
| Coro1a |
T |
C |
7: 126,300,719 (GRCm39) |
I162V |
probably benign |
Het |
| Cry1 |
T |
A |
10: 84,982,318 (GRCm39) |
I343F |
probably damaging |
Het |
| Csnk1e |
A |
T |
15: 79,309,050 (GRCm39) |
M292K |
probably benign |
Het |
| Cul7 |
T |
A |
17: 46,974,116 (GRCm39) |
L1467H |
probably damaging |
Het |
| Cul9 |
A |
T |
17: 46,836,818 (GRCm39) |
M1069K |
probably benign |
Het |
| Cyp2c67 |
C |
A |
19: 39,631,708 (GRCm39) |
|
probably benign |
Het |
| Dnah11 |
T |
C |
12: 117,979,200 (GRCm39) |
I2633V |
probably damaging |
Het |
| Eif4g3 |
C |
A |
4: 137,933,369 (GRCm39) |
D1731E |
probably damaging |
Het |
| Epb41l4b |
T |
C |
4: 57,032,204 (GRCm39) |
T592A |
probably benign |
Het |
| Evi5 |
T |
C |
5: 107,946,984 (GRCm39) |
|
probably benign |
Het |
| Exo1 |
T |
A |
1: 175,728,952 (GRCm39) |
M672K |
probably benign |
Het |
| Fcho1 |
T |
C |
8: 72,163,047 (GRCm39) |
S661G |
probably damaging |
Het |
| Fnip2 |
A |
G |
3: 79,415,475 (GRCm39) |
Y188H |
possibly damaging |
Het |
| Foxb1 |
T |
C |
9: 69,667,293 (GRCm39) |
D79G |
probably damaging |
Het |
| Fyco1 |
T |
C |
9: 123,658,346 (GRCm39) |
Y610C |
probably damaging |
Het |
| Gm3095 |
T |
A |
14: 15,170,441 (GRCm39) |
Y97N |
probably damaging |
Het |
| Gm3095 |
C |
A |
14: 15,170,440 (GRCm39) |
N96K |
probably damaging |
Het |
| Gmfb |
A |
T |
14: 47,049,237 (GRCm39) |
L128* |
probably null |
Het |
| Gprc5c |
T |
A |
11: 114,755,220 (GRCm39) |
V299D |
possibly damaging |
Het |
| Hsfy2 |
C |
T |
1: 56,676,388 (GRCm39) |
V50I |
probably benign |
Het |
| Hspa12b |
A |
C |
2: 130,982,849 (GRCm39) |
K236Q |
probably benign |
Het |
| Impg2 |
A |
G |
16: 56,080,221 (GRCm39) |
Y566C |
probably damaging |
Het |
| Itpr3 |
A |
C |
17: 27,335,581 (GRCm39) |
|
probably null |
Het |
| Kprp |
G |
A |
3: 92,732,783 (GRCm39) |
T89I |
probably damaging |
Het |
| Lcmt2 |
T |
C |
2: 120,969,133 (GRCm39) |
E650G |
probably damaging |
Het |
| Lrch1 |
T |
C |
14: 75,051,144 (GRCm39) |
D331G |
probably damaging |
Het |
| Mroh9 |
T |
A |
1: 162,852,110 (GRCm39) |
I860F |
probably benign |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Myt1l |
A |
G |
12: 29,877,396 (GRCm39) |
D349G |
unknown |
Het |
| Ndufs2 |
T |
C |
1: 171,073,690 (GRCm39) |
T31A |
probably benign |
Het |
| Ndufs3 |
A |
T |
2: 90,729,016 (GRCm39) |
S157T |
probably benign |
Het |
| Nfix |
G |
A |
8: 85,453,155 (GRCm39) |
R300C |
probably damaging |
Het |
| Noct |
T |
A |
3: 51,155,251 (GRCm39) |
S6R |
probably damaging |
Het |
| Npas2 |
T |
A |
1: 39,339,808 (GRCm39) |
H119Q |
probably damaging |
Het |
| Oprl1 |
A |
T |
2: 181,360,646 (GRCm39) |
Y207F |
probably benign |
Het |
| Or2n1e |
G |
A |
17: 38,586,557 (GRCm39) |
|
probably null |
Het |
| Or4c11 |
A |
G |
2: 88,695,871 (GRCm39) |
|
probably null |
Het |
| Or8k30 |
T |
G |
2: 86,339,193 (GRCm39) |
L130R |
probably damaging |
Het |
| Palm3 |
G |
T |
8: 84,756,291 (GRCm39) |
S601I |
possibly damaging |
Het |
| Plscr1 |
T |
A |
9: 92,148,548 (GRCm39) |
C163S |
probably damaging |
Het |
| Ptprk |
A |
T |
10: 28,369,166 (GRCm39) |
M713L |
probably benign |
Het |
| Rdm1 |
A |
G |
11: 101,519,217 (GRCm39) |
D72G |
possibly damaging |
Het |
| Reln |
T |
C |
5: 22,265,366 (GRCm39) |
D442G |
probably benign |
Het |
| Rims4 |
C |
T |
2: 163,705,849 (GRCm39) |
V262M |
possibly damaging |
Het |
| Seh1l |
T |
G |
18: 67,921,806 (GRCm39) |
V222G |
probably damaging |
Het |
| Septin12 |
T |
C |
16: 4,814,340 (GRCm39) |
K43R |
probably damaging |
Het |
| Slc25a18 |
A |
C |
6: 120,763,303 (GRCm39) |
|
probably benign |
Het |
| Slc33a1 |
T |
C |
3: 63,855,650 (GRCm39) |
T332A |
possibly damaging |
Het |
| Slc35d3 |
A |
G |
10: 19,724,909 (GRCm39) |
S316P |
probably benign |
Het |
| Spmip7 |
A |
G |
11: 11,438,641 (GRCm39) |
|
probably benign |
Het |
| Srrm2 |
T |
A |
17: 24,037,906 (GRCm39) |
|
probably benign |
Het |
| Srsf12 |
C |
T |
4: 33,230,974 (GRCm39) |
S156L |
probably damaging |
Het |
| Syce3 |
A |
G |
15: 89,274,606 (GRCm39) |
M49T |
probably benign |
Het |
| Tjp3 |
T |
C |
10: 81,112,094 (GRCm39) |
|
probably benign |
Het |
| Tnks |
G |
T |
8: 35,342,430 (GRCm39) |
N373K |
probably damaging |
Het |
| Togaram1 |
A |
G |
12: 65,013,847 (GRCm39) |
N366S |
possibly damaging |
Het |
| Trpm1 |
G |
A |
7: 63,890,283 (GRCm39) |
R962H |
probably damaging |
Het |
| Trpm6 |
A |
T |
19: 18,854,995 (GRCm39) |
M1885L |
possibly damaging |
Het |
| Tshz3 |
A |
G |
7: 36,471,221 (GRCm39) |
D1070G |
probably damaging |
Het |
| Ush2a |
T |
C |
1: 188,546,421 (GRCm39) |
M3399T |
probably benign |
Het |
| Utp15 |
G |
A |
13: 98,393,695 (GRCm39) |
T196I |
probably benign |
Het |
| Vmn1r168 |
T |
C |
7: 23,240,725 (GRCm39) |
I194T |
probably benign |
Het |
| Vmn2r73 |
C |
T |
7: 85,525,120 (GRCm39) |
W9* |
probably null |
Het |
| Wdr17 |
T |
C |
8: 55,092,930 (GRCm39) |
Y1076C |
probably damaging |
Het |
| Zan |
T |
C |
5: 137,382,092 (GRCm39) |
T5152A |
unknown |
Het |
| Zbtb46 |
A |
T |
2: 181,066,042 (GRCm39) |
V36E |
possibly damaging |
Het |
| Zfp558 |
T |
C |
9: 18,380,579 (GRCm39) |
I9M |
possibly damaging |
Het |
| Zscan2 |
T |
A |
7: 80,525,534 (GRCm39) |
Y418* |
probably null |
Het |
|
| Other mutations in Sbno1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00563:Sbno1
|
APN |
5 |
124,540,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Sbno1
|
APN |
5 |
124,548,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Sbno1
|
APN |
5 |
124,519,769 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL01330:Sbno1
|
APN |
5 |
124,530,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01541:Sbno1
|
APN |
5 |
124,516,618 (GRCm39) |
splice site |
probably benign |
|
|
IGL01800:Sbno1
|
APN |
5 |
124,519,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL01987:Sbno1
|
APN |
5 |
124,542,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02178:Sbno1
|
APN |
5 |
124,538,258 (GRCm39) |
splice site |
probably null |
|
|
IGL02544:Sbno1
|
APN |
5 |
124,542,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02572:Sbno1
|
APN |
5 |
124,519,740 (GRCm39) |
splice site |
probably benign |
|
|
IGL02592:Sbno1
|
APN |
5 |
124,538,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03033:Sbno1
|
APN |
5 |
124,514,213 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03089:Sbno1
|
APN |
5 |
124,525,374 (GRCm39) |
splice site |
probably benign |
|
|
IGL03131:Sbno1
|
APN |
5 |
124,526,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Decrement
|
UTSW |
5 |
124,538,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Sbno1
|
UTSW |
5 |
124,522,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0217:Sbno1
|
UTSW |
5 |
124,542,387 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0233:Sbno1
|
UTSW |
5 |
124,514,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0233:Sbno1
|
UTSW |
5 |
124,514,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0334:Sbno1
|
UTSW |
5 |
124,524,931 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0401:Sbno1
|
UTSW |
5 |
124,548,348 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0608:Sbno1
|
UTSW |
5 |
124,522,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0615:Sbno1
|
UTSW |
5 |
124,548,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Sbno1
|
UTSW |
5 |
124,524,955 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0655:Sbno1
|
UTSW |
5 |
124,514,212 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1037:Sbno1
|
UTSW |
5 |
124,531,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1439:Sbno1
|
UTSW |
5 |
124,522,523 (GRCm39) |
splice site |
probably benign |
|
|
R1522:Sbno1
|
UTSW |
5 |
124,530,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1590:Sbno1
|
UTSW |
5 |
124,522,567 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1671:Sbno1
|
UTSW |
5 |
124,530,130 (GRCm39) |
splice site |
probably null |
|
|
R1779:Sbno1
|
UTSW |
5 |
124,526,580 (GRCm39) |
unclassified |
probably benign |
|
|
R2103:Sbno1
|
UTSW |
5 |
124,532,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2136:Sbno1
|
UTSW |
5 |
124,525,597 (GRCm39) |
splice site |
probably null |
|
|
R2149:Sbno1
|
UTSW |
5 |
124,540,182 (GRCm39) |
splice site |
probably null |
|
|
R2153:Sbno1
|
UTSW |
5 |
124,516,606 (GRCm39) |
missense |
probably benign |
|
|
R2154:Sbno1
|
UTSW |
5 |
124,516,574 (GRCm39) |
missense |
probably benign |
|
|
R2231:Sbno1
|
UTSW |
5 |
124,543,767 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2879:Sbno1
|
UTSW |
5 |
124,526,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3004:Sbno1
|
UTSW |
5 |
124,519,771 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3922:Sbno1
|
UTSW |
5 |
124,519,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4061:Sbno1
|
UTSW |
5 |
124,526,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4096:Sbno1
|
UTSW |
5 |
124,529,983 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4612:Sbno1
|
UTSW |
5 |
124,542,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4879:Sbno1
|
UTSW |
5 |
124,542,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Sbno1
|
UTSW |
5 |
124,512,672 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4990:Sbno1
|
UTSW |
5 |
124,538,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5341:Sbno1
|
UTSW |
5 |
124,546,538 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5365:Sbno1
|
UTSW |
5 |
124,519,929 (GRCm39) |
frame shift |
probably null |
|
|
R5399:Sbno1
|
UTSW |
5 |
124,530,804 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5704:Sbno1
|
UTSW |
5 |
124,533,956 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5898:Sbno1
|
UTSW |
5 |
124,524,854 (GRCm39) |
intron |
probably benign |
|
|
R6136:Sbno1
|
UTSW |
5 |
124,516,554 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6154:Sbno1
|
UTSW |
5 |
124,516,542 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6412:Sbno1
|
UTSW |
5 |
124,530,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6414:Sbno1
|
UTSW |
5 |
124,533,994 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6454:Sbno1
|
UTSW |
5 |
124,538,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7085:Sbno1
|
UTSW |
5 |
124,519,783 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7176:Sbno1
|
UTSW |
5 |
124,530,944 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7219:Sbno1
|
UTSW |
5 |
124,543,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7535:Sbno1
|
UTSW |
5 |
124,551,342 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7673:Sbno1
|
UTSW |
5 |
124,551,279 (GRCm39) |
missense |
probably benign |
|
|
R7692:Sbno1
|
UTSW |
5 |
124,543,709 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7745:Sbno1
|
UTSW |
5 |
124,530,962 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7762:Sbno1
|
UTSW |
5 |
124,512,729 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8012:Sbno1
|
UTSW |
5 |
124,522,565 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8142:Sbno1
|
UTSW |
5 |
124,546,608 (GRCm39) |
missense |
probably benign |
|
|
R8164:Sbno1
|
UTSW |
5 |
124,512,684 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8259:Sbno1
|
UTSW |
5 |
124,519,759 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8289:Sbno1
|
UTSW |
5 |
124,542,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Sbno1
|
UTSW |
5 |
124,512,618 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9045:Sbno1
|
UTSW |
5 |
124,543,720 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9149:Sbno1
|
UTSW |
5 |
124,519,762 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9529:Sbno1
|
UTSW |
5 |
124,517,413 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Sbno1
|
UTSW |
5 |
124,542,367 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Sbno1
|
UTSW |
5 |
124,532,021 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGATTGATAGCCCCACTGAACAAGG -3'
(R):5'- GCTAACTGTCCCCATGATTTACGTACC -3'
Sequencing Primer
(F):5'- CCATACCTTATTTAACGAATGGACC -3'
(R):5'- TTACGTACCACATGGAAGTTGG -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation