Incidental Mutation 'R1619:Helz'
| ID |
174551 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Helz
|
| Ensembl Gene |
ENSMUSG00000020721 |
| Gene Name |
helicase with zinc finger domain |
| Synonyms |
3110078M01Rik, 9430093I07Rik, 9630002H22Rik |
| MMRRC Submission |
039656-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1619 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
107438756-107584652 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 107527105 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 182
(C182*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000117498
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075012]
[ENSMUST00000100305]
[ENSMUST00000106746]
[ENSMUST00000133862]
|
| AlphaFold |
Q6DFV5 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000075012
AA Change: C864*
|
| SMART Domains |
Protein: ENSMUSP00000074533
Gene: ENSMUSG00000020721
AA Change: C864*
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:ResIII
|
639 |
807 |
6.7e-8 |
PFAM |
|
Pfam:AAA_11
|
641 |
768 |
2.3e-14 |
PFAM |
|
Pfam:AAA_30
|
641 |
838 |
2.6e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
729 |
5.5e-11 |
PFAM |
|
Pfam:AAA_11
|
758 |
834 |
3.8e-18 |
PFAM |
|
Pfam:AAA_12
|
841 |
1053 |
7.4e-38 |
PFAM |
|
low complexity region
|
1165 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1448 |
N/A |
INTRINSIC |
|
low complexity region
|
1466 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1557 |
1568 |
N/A |
INTRINSIC |
|
low complexity region
|
1631 |
1647 |
N/A |
INTRINSIC |
|
low complexity region
|
1716 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1926 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1942 |
1957 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000100305
AA Change: C863*
|
| SMART Domains |
Protein: ENSMUSP00000097878
Gene: ENSMUSG00000020721
AA Change: C863*
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
2.7e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
1.7e-10 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
6.3e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
3.4e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106746
AA Change: C863*
|
| SMART Domains |
Protein: ENSMUSP00000102357
Gene: ENSMUSG00000020721
AA Change: C863*
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
6 |
84 |
5e-3 |
SMART |
|
low complexity region
|
129 |
146 |
N/A |
INTRINSIC |
|
ZnF_C3H1
|
178 |
205 |
2.61e-4 |
SMART |
|
Pfam:AAA_11
|
641 |
833 |
1e-31 |
PFAM |
|
Pfam:AAA_30
|
641 |
837 |
8.3e-11 |
PFAM |
|
Pfam:AAA_19
|
648 |
727 |
2.2e-9 |
PFAM |
|
Pfam:AAA_12
|
840 |
1052 |
1.7e-36 |
PFAM |
|
low complexity region
|
1164 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1465 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1556 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1630 |
1646 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1735 |
N/A |
INTRINSIC |
|
low complexity region
|
1925 |
1932 |
N/A |
INTRINSIC |
|
low complexity region
|
1941 |
1956 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000133862
AA Change: C182*
|
| SMART Domains |
Protein: ENSMUSP00000117498
Gene: ENSMUSG00000020721
AA Change: C182*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
68 |
152 |
2.1e-19 |
PFAM |
|
Pfam:AAA_12
|
159 |
371 |
1.5e-36 |
PFAM |
|
low complexity region
|
483 |
494 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
766 |
N/A |
INTRINSIC |
|
low complexity region
|
784 |
805 |
N/A |
INTRINSIC |
|
low complexity region
|
875 |
886 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143634
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185044
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 95.8%
- 20x: 91.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene-trapped allele are viable, fertile and phenotypically normal with no apparent skeletal defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca7 |
A |
T |
10: 79,844,889 (GRCm39) |
H1537L |
probably damaging |
Het |
| Actg2 |
T |
A |
6: 83,500,169 (GRCm39) |
N116I |
probably damaging |
Het |
| Actn1 |
G |
A |
12: 80,219,796 (GRCm39) |
H692Y |
probably damaging |
Het |
| Adamts6 |
C |
T |
13: 104,449,285 (GRCm39) |
P36S |
probably benign |
Het |
| Agr3 |
G |
A |
12: 35,997,858 (GRCm39) |
|
probably null |
Het |
| Ank3 |
T |
C |
10: 69,715,805 (GRCm39) |
V500A |
probably damaging |
Het |
| BC051019 |
T |
A |
7: 109,317,269 (GRCm39) |
D141V |
probably damaging |
Het |
| Bco1 |
T |
C |
8: 117,835,454 (GRCm39) |
F135S |
probably damaging |
Het |
| Cacna1c |
C |
T |
6: 118,589,586 (GRCm39) |
R1446H |
probably damaging |
Het |
| Ccdc42 |
A |
G |
11: 68,485,115 (GRCm39) |
K210E |
probably damaging |
Het |
| Cckar |
A |
T |
5: 53,857,409 (GRCm39) |
W263R |
probably damaging |
Het |
| Cela2a |
A |
G |
4: 141,553,252 (GRCm39) |
|
probably null |
Het |
| Cep97 |
A |
T |
16: 55,748,159 (GRCm39) |
N90K |
probably damaging |
Het |
| Ces2g |
A |
T |
8: 105,693,984 (GRCm39) |
Q440L |
probably damaging |
Het |
| Chchd6 |
G |
T |
6: 89,396,736 (GRCm39) |
T225K |
possibly damaging |
Het |
| Chd1l |
C |
T |
3: 97,490,047 (GRCm39) |
E503K |
probably benign |
Het |
| Chrna5 |
A |
G |
9: 54,911,649 (GRCm39) |
T46A |
probably benign |
Het |
| Col16a1 |
G |
A |
4: 129,992,733 (GRCm39) |
G1531S |
probably damaging |
Het |
| Col19a1 |
A |
T |
1: 24,573,172 (GRCm39) |
V200E |
unknown |
Het |
| Csf2rb |
A |
G |
15: 78,219,411 (GRCm39) |
D2G |
probably damaging |
Het |
| Csmd3 |
G |
A |
15: 47,813,346 (GRCm39) |
S1062L |
probably damaging |
Het |
| Cul5 |
G |
T |
9: 53,569,893 (GRCm39) |
Q113K |
probably benign |
Het |
| Dmwd |
TAGCCTGGGAA |
TAGCCTGGGAAGCCTGGGAA |
7: 18,814,959 (GRCm39) |
|
probably benign |
Het |
| Dse |
T |
C |
10: 34,029,230 (GRCm39) |
D620G |
probably damaging |
Het |
| Dsg1c |
A |
G |
18: 20,397,899 (GRCm39) |
N33S |
probably benign |
Het |
| Epc2 |
G |
A |
2: 49,439,990 (GRCm39) |
V803I |
probably damaging |
Het |
| Erap1 |
T |
A |
13: 74,819,500 (GRCm39) |
H171Q |
probably damaging |
Het |
| Esrrb |
T |
C |
12: 86,561,274 (GRCm39) |
V336A |
possibly damaging |
Het |
| Fech |
A |
T |
18: 64,595,189 (GRCm39) |
W300R |
probably damaging |
Het |
| Fgd4 |
T |
C |
16: 16,241,920 (GRCm39) |
I635V |
possibly damaging |
Het |
| Galc |
A |
T |
12: 98,200,563 (GRCm39) |
N282K |
probably benign |
Het |
| Gpat2 |
A |
G |
2: 127,270,637 (GRCm39) |
Y95C |
probably benign |
Het |
| Grm2 |
T |
A |
9: 106,524,670 (GRCm39) |
I682F |
probably damaging |
Het |
| Hdac10 |
G |
T |
15: 89,010,878 (GRCm39) |
A241D |
probably damaging |
Het |
| Ift140 |
A |
G |
17: 25,307,839 (GRCm39) |
Y978C |
probably damaging |
Het |
| Intu |
T |
A |
3: 40,652,061 (GRCm39) |
C839* |
probably null |
Het |
| Jmjd1c |
T |
C |
10: 67,055,654 (GRCm39) |
V358A |
probably benign |
Het |
| Kif26b |
A |
G |
1: 178,744,043 (GRCm39) |
S1380G |
probably benign |
Het |
| Lrp1b |
A |
G |
2: 40,587,601 (GRCm39) |
S116P |
unknown |
Het |
| Lrrc2 |
T |
A |
9: 110,790,041 (GRCm39) |
S99R |
probably benign |
Het |
| Mrpl48 |
G |
A |
7: 100,195,482 (GRCm39) |
|
probably benign |
Het |
| Mup9 |
A |
G |
4: 60,377,878 (GRCm39) |
|
probably benign |
Het |
| Nap1l1 |
G |
A |
10: 111,329,240 (GRCm39) |
V285I |
possibly damaging |
Het |
| Nepro |
A |
G |
16: 44,547,391 (GRCm39) |
D36G |
probably benign |
Het |
| Nkain4 |
A |
G |
2: 180,577,794 (GRCm39) |
F187L |
probably damaging |
Het |
| Nobox |
A |
T |
6: 43,284,401 (GRCm39) |
C82S |
possibly damaging |
Het |
| Ntn4 |
C |
A |
10: 93,480,596 (GRCm39) |
Q70K |
probably damaging |
Het |
| Or13j1 |
A |
G |
4: 43,706,292 (GRCm39) |
I92T |
probably damaging |
Het |
| Or1e26 |
A |
T |
11: 73,480,118 (GRCm39) |
W149R |
probably damaging |
Het |
| Or4k37 |
A |
G |
2: 111,159,306 (GRCm39) |
I181V |
probably benign |
Het |
| Or51a43 |
T |
C |
7: 103,717,738 (GRCm39) |
R167G |
probably damaging |
Het |
| Or5b122 |
T |
A |
19: 13,562,978 (GRCm39) |
F103L |
probably benign |
Het |
| Or9r3 |
A |
G |
10: 129,948,548 (GRCm39) |
I37T |
possibly damaging |
Het |
| Pappa |
A |
G |
4: 65,094,466 (GRCm39) |
E497G |
probably damaging |
Het |
| Pard3 |
C |
A |
8: 128,106,983 (GRCm39) |
T569K |
probably benign |
Het |
| Parp14 |
G |
A |
16: 35,677,130 (GRCm39) |
A946V |
probably benign |
Het |
| Pcdh10 |
A |
G |
3: 45,334,747 (GRCm39) |
N354D |
possibly damaging |
Het |
| Pdgfc |
T |
C |
3: 81,082,194 (GRCm39) |
V129A |
probably benign |
Het |
| Pdia3 |
G |
A |
2: 121,262,858 (GRCm39) |
G275S |
probably damaging |
Het |
| Phf20l1 |
A |
T |
15: 66,487,108 (GRCm39) |
H407L |
possibly damaging |
Het |
| Phip |
A |
T |
9: 82,753,502 (GRCm39) |
D1747E |
probably benign |
Het |
| Pkd1l1 |
A |
G |
11: 8,900,413 (GRCm39) |
S43P |
probably damaging |
Het |
| Plekhg2 |
T |
C |
7: 28,067,846 (GRCm39) |
E202G |
probably damaging |
Het |
| Rapsn |
A |
G |
2: 90,873,504 (GRCm39) |
D270G |
possibly damaging |
Het |
| Rims2 |
A |
C |
15: 39,370,382 (GRCm39) |
S939R |
probably damaging |
Het |
| Ripor3 |
T |
C |
2: 167,822,765 (GRCm39) |
D932G |
probably damaging |
Het |
| Rtp2 |
A |
T |
16: 23,749,421 (GRCm39) |
W30R |
probably damaging |
Het |
| Scgb2b27 |
A |
T |
7: 33,711,557 (GRCm39) |
D97E |
probably benign |
Het |
| Slc25a46 |
T |
C |
18: 31,716,542 (GRCm39) |
N320S |
probably benign |
Het |
| Slc9b1 |
A |
G |
3: 135,060,765 (GRCm39) |
|
probably null |
Het |
| Socs4 |
T |
A |
14: 47,527,740 (GRCm39) |
M225K |
possibly damaging |
Het |
| Spata31d1a |
A |
T |
13: 59,850,247 (GRCm39) |
L627* |
probably null |
Het |
| Srcin1 |
A |
G |
11: 97,416,307 (GRCm39) |
L975P |
probably damaging |
Het |
| Stard3 |
T |
A |
11: 98,267,435 (GRCm39) |
|
probably null |
Het |
| Susd2 |
G |
T |
10: 75,473,878 (GRCm39) |
S572R |
possibly damaging |
Het |
| Tll1 |
C |
A |
8: 64,509,307 (GRCm39) |
A568S |
probably benign |
Het |
| Tmem132a |
C |
G |
19: 10,839,062 (GRCm39) |
G460A |
probably damaging |
Het |
| Trim62 |
A |
G |
4: 128,803,281 (GRCm39) |
K444E |
probably damaging |
Het |
| Trpm3 |
A |
G |
19: 22,689,271 (GRCm39) |
T67A |
probably damaging |
Het |
| Ttc6 |
T |
C |
12: 57,784,454 (GRCm39) |
M1841T |
possibly damaging |
Het |
| Ulk2 |
A |
T |
11: 61,672,572 (GRCm39) |
V922D |
probably damaging |
Het |
| Vmn2r38 |
C |
A |
7: 9,078,532 (GRCm39) |
V617L |
probably damaging |
Het |
| Xkr6 |
G |
A |
14: 64,056,766 (GRCm39) |
V226M |
probably benign |
Het |
| Zfp940 |
G |
A |
7: 29,544,962 (GRCm39) |
A315V |
possibly damaging |
Het |
| Zfr |
C |
A |
15: 12,150,473 (GRCm39) |
T480K |
possibly damaging |
Het |
|
| Other mutations in Helz |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00971:Helz
|
APN |
11 |
107,554,479 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01419:Helz
|
APN |
11 |
107,577,340 (GRCm39) |
missense |
unknown |
|
|
IGL01864:Helz
|
APN |
11 |
107,493,180 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01999:Helz
|
APN |
11 |
107,493,754 (GRCm39) |
splice site |
probably benign |
|
|
IGL02938:Helz
|
APN |
11 |
107,577,264 (GRCm39) |
missense |
unknown |
|
|
IGL03157:Helz
|
APN |
11 |
107,468,714 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03374:Helz
|
APN |
11 |
107,510,973 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0058:Helz
|
UTSW |
11 |
107,563,384 (GRCm39) |
unclassified |
probably benign |
|
|
R0112:Helz
|
UTSW |
11 |
107,563,774 (GRCm39) |
unclassified |
probably benign |
|
|
R0243:Helz
|
UTSW |
11 |
107,528,740 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0328:Helz
|
UTSW |
11 |
107,495,174 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0578:Helz
|
UTSW |
11 |
107,577,226 (GRCm39) |
missense |
unknown |
|
|
R0928:Helz
|
UTSW |
11 |
107,517,519 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1428:Helz
|
UTSW |
11 |
107,483,666 (GRCm39) |
splice site |
probably benign |
|
|
R1493:Helz
|
UTSW |
11 |
107,504,751 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1494:Helz
|
UTSW |
11 |
107,494,889 (GRCm39) |
splice site |
probably benign |
|
|
R1541:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1809:Helz
|
UTSW |
11 |
107,489,997 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1942:Helz
|
UTSW |
11 |
107,493,318 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2095:Helz
|
UTSW |
11 |
107,536,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Helz
|
UTSW |
11 |
107,561,310 (GRCm39) |
missense |
unknown |
|
|
R2167:Helz
|
UTSW |
11 |
107,563,790 (GRCm39) |
unclassified |
probably benign |
|
|
R2406:Helz
|
UTSW |
11 |
107,577,378 (GRCm39) |
missense |
unknown |
|
|
R2571:Helz
|
UTSW |
11 |
107,504,778 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2858:Helz
|
UTSW |
11 |
107,563,753 (GRCm39) |
unclassified |
probably benign |
|
|
R3927:Helz
|
UTSW |
11 |
107,576,118 (GRCm39) |
missense |
unknown |
|
|
R4449:Helz
|
UTSW |
11 |
107,494,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4453:Helz
|
UTSW |
11 |
107,563,455 (GRCm39) |
nonsense |
probably null |
|
|
R4583:Helz
|
UTSW |
11 |
107,536,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Helz
|
UTSW |
11 |
107,539,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4714:Helz
|
UTSW |
11 |
107,517,542 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4875:Helz
|
UTSW |
11 |
107,528,560 (GRCm39) |
intron |
probably benign |
|
|
R4924:Helz
|
UTSW |
11 |
107,493,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4930:Helz
|
UTSW |
11 |
107,510,994 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5078:Helz
|
UTSW |
11 |
107,546,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5446:Helz
|
UTSW |
11 |
107,523,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5535:Helz
|
UTSW |
11 |
107,536,946 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5650:Helz
|
UTSW |
11 |
107,485,972 (GRCm39) |
missense |
probably null |
0.96 |
|
R5714:Helz
|
UTSW |
11 |
107,517,347 (GRCm39) |
splice site |
probably null |
|
|
R5784:Helz
|
UTSW |
11 |
107,561,307 (GRCm39) |
missense |
unknown |
|
|
R5998:Helz
|
UTSW |
11 |
107,576,360 (GRCm39) |
nonsense |
probably null |
|
|
R6042:Helz
|
UTSW |
11 |
107,504,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6089:Helz
|
UTSW |
11 |
107,485,963 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6137:Helz
|
UTSW |
11 |
107,509,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6373:Helz
|
UTSW |
11 |
107,486,010 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6392:Helz
|
UTSW |
11 |
107,493,167 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6618:Helz
|
UTSW |
11 |
107,489,976 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6644:Helz
|
UTSW |
11 |
107,523,087 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6811:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6874:Helz
|
UTSW |
11 |
107,554,460 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6911:Helz
|
UTSW |
11 |
107,510,051 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7039:Helz
|
UTSW |
11 |
107,510,144 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7061:Helz
|
UTSW |
11 |
107,540,003 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7438:Helz
|
UTSW |
11 |
107,552,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7464:Helz
|
UTSW |
11 |
107,527,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7513:Helz
|
UTSW |
11 |
107,546,941 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7559:Helz
|
UTSW |
11 |
107,491,104 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7734:Helz
|
UTSW |
11 |
107,576,248 (GRCm39) |
missense |
unknown |
|
|
R7780:Helz
|
UTSW |
11 |
107,528,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7982:Helz
|
UTSW |
11 |
107,517,456 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8024:Helz
|
UTSW |
11 |
107,577,247 (GRCm39) |
missense |
unknown |
|
|
R8181:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8346:Helz
|
UTSW |
11 |
107,563,399 (GRCm39) |
missense |
unknown |
|
|
R8729:Helz
|
UTSW |
11 |
107,528,754 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8807:Helz
|
UTSW |
11 |
107,493,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8821:Helz
|
UTSW |
11 |
107,525,919 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8891:Helz
|
UTSW |
11 |
107,552,842 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8909:Helz
|
UTSW |
11 |
107,556,834 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8922:Helz
|
UTSW |
11 |
107,539,985 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8926:Helz
|
UTSW |
11 |
107,563,509 (GRCm39) |
missense |
unknown |
|
|
R8988:Helz
|
UTSW |
11 |
107,495,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9053:Helz
|
UTSW |
11 |
107,563,761 (GRCm39) |
missense |
unknown |
|
|
R9056:Helz
|
UTSW |
11 |
107,547,019 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9099:Helz
|
UTSW |
11 |
107,523,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9122:Helz
|
UTSW |
11 |
107,556,830 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9194:Helz
|
UTSW |
11 |
107,561,113 (GRCm39) |
nonsense |
probably null |
|
|
R9220:Helz
|
UTSW |
11 |
107,560,873 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9223:Helz
|
UTSW |
11 |
107,509,918 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9242:Helz
|
UTSW |
11 |
107,523,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9644:Helz
|
UTSW |
11 |
107,563,687 (GRCm39) |
missense |
unknown |
|
|
R9761:Helz
|
UTSW |
11 |
107,560,874 (GRCm39) |
nonsense |
probably null |
|
|
X0065:Helz
|
UTSW |
11 |
107,561,273 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTGTGCTACACTGAGAAGCGAG -3'
(R):5'- CAAGTTAGGCAAAGTCTGAGACCCC -3'
Sequencing Primer
(F):5'- CTCTAGTCTGGTTCCACGGAATAG -3'
(R):5'- AAGTCTGAGACCCCCAAAAG -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation