Incidental Mutation 'R1623:Hivep3'
| ID |
174772 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hivep3
|
| Ensembl Gene |
ENSMUSG00000028634 |
| Gene Name |
human immunodeficiency virus type I enhancer binding protein 3 |
| Synonyms |
Krc, E030045D18Rik, Schnurri-3, Shn3, 2900056N03Rik |
| MMRRC Submission |
039660-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1623 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
119590982-119992608 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 119952901 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 406
(S406P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130249
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106307]
[ENSMUST00000166542]
[ENSMUST00000226560]
|
| AlphaFold |
A2A884 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000106307
AA Change: S406P
PolyPhen 2
Score 0.838 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101914
Gene: ENSMUSG00000028634
AA Change: S406P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000166542
AA Change: S406P
PolyPhen 2
Score 0.838 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000130249
Gene: ENSMUSG00000028634
AA Change: S406P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226560
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.0%
- 10x: 94.9%
- 20x: 87.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygous mutation of this gene results in diminished IL-2 production by stimulated CD4 cells. Mice homozygous for a knock-out allele exhibit increased bone volume. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acbd5 |
A |
T |
2: 22,984,356 (GRCm39) |
D294V |
probably damaging |
Het |
| Actn2 |
A |
T |
13: 12,355,320 (GRCm39) |
I21N |
probably benign |
Het |
| Adamts2 |
C |
A |
11: 50,558,942 (GRCm39) |
P219H |
possibly damaging |
Het |
| Atg16l2 |
A |
G |
7: 100,939,113 (GRCm39) |
F584L |
probably benign |
Het |
| Ccdc81 |
C |
T |
7: 89,535,390 (GRCm39) |
R282Q |
probably benign |
Het |
| Ccn4 |
G |
T |
15: 66,763,448 (GRCm39) |
V12L |
possibly damaging |
Het |
| Cd200r3 |
G |
A |
16: 44,771,811 (GRCm39) |
C25Y |
possibly damaging |
Het |
| Cdkl4 |
C |
T |
17: 80,863,731 (GRCm39) |
|
probably null |
Het |
| Chrne |
T |
C |
11: 70,509,254 (GRCm39) |
E109G |
possibly damaging |
Het |
| Clmp |
A |
G |
9: 40,693,856 (GRCm39) |
T358A |
probably benign |
Het |
| Cmtr1 |
G |
T |
17: 29,906,021 (GRCm39) |
|
probably null |
Het |
| Col25a1 |
A |
G |
3: 130,343,699 (GRCm39) |
E389G |
probably damaging |
Het |
| Ctc1 |
C |
T |
11: 68,911,968 (GRCm39) |
T49M |
probably damaging |
Het |
| Cyth3 |
T |
A |
5: 143,687,127 (GRCm39) |
M120K |
probably damaging |
Het |
| D430041D05Rik |
T |
A |
2: 103,983,308 (GRCm39) |
E1996V |
probably damaging |
Het |
| Dnah9 |
T |
C |
11: 65,928,463 (GRCm39) |
M2069V |
probably damaging |
Het |
| Dsg1c |
T |
C |
18: 20,408,234 (GRCm39) |
Y428H |
probably damaging |
Het |
| Exosc8 |
T |
A |
3: 54,641,752 (GRCm39) |
T7S |
probably damaging |
Het |
| F5 |
A |
G |
1: 164,023,191 (GRCm39) |
Y1583C |
probably damaging |
Het |
| Fam178b |
A |
G |
1: 36,683,405 (GRCm39) |
I105T |
probably damaging |
Het |
| Fam181a |
T |
A |
12: 103,282,591 (GRCm39) |
Y165* |
probably null |
Het |
| Fbn2 |
G |
T |
18: 58,181,620 (GRCm39) |
N1880K |
possibly damaging |
Het |
| Gbgt1 |
A |
T |
2: 28,394,988 (GRCm39) |
M209L |
probably benign |
Het |
| Gkn2 |
C |
A |
6: 87,355,152 (GRCm39) |
Y120* |
probably null |
Het |
| Gm14295 |
T |
A |
2: 176,499,157 (GRCm39) |
D1E |
probably damaging |
Het |
| Gpr141 |
A |
T |
13: 19,936,082 (GRCm39) |
|
probably null |
Het |
| Gramd2b |
C |
A |
18: 56,565,423 (GRCm39) |
P26Q |
probably benign |
Het |
| Greb1 |
A |
G |
12: 16,724,771 (GRCm39) |
I1801T |
probably damaging |
Het |
| Gstm3 |
T |
A |
3: 107,875,151 (GRCm39) |
I64F |
possibly damaging |
Het |
| Gtse1 |
A |
G |
15: 85,751,779 (GRCm39) |
Y324C |
probably benign |
Het |
| Hal |
C |
G |
10: 93,352,159 (GRCm39) |
T650R |
probably benign |
Het |
| Hdac7 |
G |
A |
15: 97,706,285 (GRCm39) |
Q293* |
probably null |
Het |
| Hdlbp |
A |
T |
1: 93,351,591 (GRCm39) |
N437K |
probably damaging |
Het |
| Hif1an |
A |
G |
19: 44,557,862 (GRCm39) |
D248G |
probably damaging |
Het |
| Hmcn2 |
A |
T |
2: 31,348,051 (GRCm39) |
D4899V |
possibly damaging |
Het |
| Ikzf3 |
C |
T |
11: 98,381,157 (GRCm39) |
|
probably null |
Het |
| Inka2 |
G |
A |
3: 105,624,136 (GRCm39) |
G151D |
probably damaging |
Het |
| Itgb4 |
C |
A |
11: 115,882,142 (GRCm39) |
Y819* |
probably null |
Het |
| Itpripl1 |
T |
C |
2: 126,983,555 (GRCm39) |
D189G |
possibly damaging |
Het |
| Kmt2e |
A |
G |
5: 23,687,500 (GRCm39) |
Y450C |
probably damaging |
Het |
| Mc4r |
A |
G |
18: 66,993,068 (GRCm39) |
L15P |
probably benign |
Het |
| Mical1 |
T |
G |
10: 41,357,389 (GRCm39) |
|
probably null |
Het |
| Mical3 |
C |
T |
6: 121,001,768 (GRCm39) |
V575M |
probably damaging |
Het |
| Mki67 |
A |
T |
7: 135,310,547 (GRCm39) |
|
probably null |
Het |
| Mocs2 |
G |
A |
13: 114,961,158 (GRCm39) |
E52K |
probably benign |
Het |
| Myo7b |
T |
C |
18: 32,133,104 (GRCm39) |
N415S |
probably damaging |
Het |
| Notch1 |
G |
A |
2: 26,368,624 (GRCm39) |
T555I |
possibly damaging |
Het |
| Notch3 |
T |
C |
17: 32,358,165 (GRCm39) |
D1686G |
probably benign |
Het |
| Oit3 |
A |
G |
10: 59,264,061 (GRCm39) |
F358L |
probably damaging |
Het |
| Or10x1 |
A |
C |
1: 174,196,515 (GRCm39) |
I11L |
probably benign |
Het |
| Or6k4 |
A |
T |
1: 173,964,883 (GRCm39) |
D191V |
probably damaging |
Het |
| Orai1 |
T |
A |
5: 123,167,265 (GRCm39) |
I146N |
probably damaging |
Het |
| Pck1 |
A |
G |
2: 172,996,511 (GRCm39) |
I142V |
probably benign |
Het |
| Pdap1 |
C |
T |
5: 145,069,739 (GRCm39) |
V89M |
possibly damaging |
Het |
| Phf11a |
T |
C |
14: 59,525,000 (GRCm39) |
D68G |
possibly damaging |
Het |
| Pilrb2 |
T |
C |
5: 137,869,510 (GRCm39) |
N30S |
probably damaging |
Het |
| Pkd1 |
G |
A |
17: 24,797,243 (GRCm39) |
V2551I |
probably damaging |
Het |
| Pnpla7 |
T |
C |
2: 24,942,611 (GRCm39) |
V132A |
probably damaging |
Het |
| Prr35 |
G |
A |
17: 26,166,508 (GRCm39) |
P343L |
probably benign |
Het |
| Rad18 |
C |
T |
6: 112,605,480 (GRCm39) |
S398N |
probably damaging |
Het |
| Rdh16f1 |
C |
A |
10: 127,626,722 (GRCm39) |
N258K |
probably benign |
Het |
| Riox2 |
A |
G |
16: 59,303,405 (GRCm39) |
H240R |
probably damaging |
Het |
| Ruvbl1 |
C |
T |
6: 88,462,752 (GRCm39) |
A292V |
probably damaging |
Het |
| Ryr1 |
C |
T |
7: 28,794,915 (GRCm39) |
G1151S |
probably damaging |
Het |
| Serpinb9b |
T |
C |
13: 33,213,548 (GRCm39) |
I35T |
possibly damaging |
Het |
| Slc1a1 |
T |
A |
19: 28,882,122 (GRCm39) |
M328K |
probably benign |
Het |
| Slc7a13 |
A |
T |
4: 19,824,031 (GRCm39) |
T267S |
possibly damaging |
Het |
| Speer3 |
G |
T |
5: 13,846,335 (GRCm39) |
M218I |
probably benign |
Het |
| Sptan1 |
A |
G |
2: 29,876,432 (GRCm39) |
I271V |
probably damaging |
Het |
| Swap70 |
A |
G |
7: 109,863,255 (GRCm39) |
T195A |
probably benign |
Het |
| Tgs1 |
T |
A |
4: 3,585,964 (GRCm39) |
N280K |
probably benign |
Het |
| Tonsl |
A |
G |
15: 76,522,709 (GRCm39) |
C181R |
probably damaging |
Het |
| Trdn |
A |
G |
10: 33,134,098 (GRCm39) |
K333R |
possibly damaging |
Het |
| Trpc4 |
T |
A |
3: 54,206,600 (GRCm39) |
M600K |
probably damaging |
Het |
| Ubr3 |
C |
T |
2: 69,808,067 (GRCm39) |
Q1183* |
probably null |
Het |
| Ubxn4 |
T |
A |
1: 128,200,588 (GRCm39) |
L360I |
possibly damaging |
Het |
| Ugt2b1 |
T |
A |
5: 87,074,267 (GRCm39) |
T31S |
probably benign |
Het |
| Uspl1 |
T |
C |
5: 149,152,009 (GRCm39) |
S1056P |
probably damaging |
Het |
| Vmn2r60 |
A |
T |
7: 41,785,279 (GRCm39) |
K164* |
probably null |
Het |
| Vwce |
T |
A |
19: 10,624,108 (GRCm39) |
L333* |
probably null |
Het |
| Wdr95 |
T |
A |
5: 149,497,581 (GRCm39) |
L253Q |
probably damaging |
Het |
| Zfp113 |
T |
C |
5: 138,143,930 (GRCm39) |
M107V |
probably benign |
Het |
| Zfp142 |
T |
C |
1: 74,610,934 (GRCm39) |
T851A |
possibly damaging |
Het |
|
| Other mutations in Hivep3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00953:Hivep3
|
APN |
4 |
119,955,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01017:Hivep3
|
APN |
4 |
119,956,443 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01837:Hivep3
|
APN |
4 |
119,951,759 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01878:Hivep3
|
APN |
4 |
119,952,424 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02134:Hivep3
|
APN |
4 |
119,990,771 (GRCm39) |
splice site |
probably benign |
|
|
IGL02183:Hivep3
|
APN |
4 |
119,989,221 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02350:Hivep3
|
APN |
4 |
119,980,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02451:Hivep3
|
APN |
4 |
119,991,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02567:Hivep3
|
APN |
4 |
119,991,153 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02617:Hivep3
|
APN |
4 |
119,952,641 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02725:Hivep3
|
APN |
4 |
119,953,019 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02828:Hivep3
|
APN |
4 |
119,954,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL02954:Hivep3
|
APN |
4 |
119,990,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02966:Hivep3
|
APN |
4 |
119,989,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
Branchial
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
Deceit
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
Mandible
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Sclerotic
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Stealth
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
Yellowjacket
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4260001:Hivep3
|
UTSW |
4 |
119,956,379 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Hivep3
|
UTSW |
4 |
119,952,788 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0336:Hivep3
|
UTSW |
4 |
119,961,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0558:Hivep3
|
UTSW |
4 |
119,953,763 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0562:Hivep3
|
UTSW |
4 |
119,953,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0637:Hivep3
|
UTSW |
4 |
119,989,738 (GRCm39) |
nonsense |
probably null |
|
|
R0645:Hivep3
|
UTSW |
4 |
119,954,531 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1186:Hivep3
|
UTSW |
4 |
119,671,920 (GRCm39) |
start gained |
probably benign |
|
|
R1254:Hivep3
|
UTSW |
4 |
119,956,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Hivep3
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1739:Hivep3
|
UTSW |
4 |
119,952,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1766:Hivep3
|
UTSW |
4 |
119,953,868 (GRCm39) |
missense |
probably benign |
|
|
R1769:Hivep3
|
UTSW |
4 |
119,954,768 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1773:Hivep3
|
UTSW |
4 |
119,956,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Hivep3
|
UTSW |
4 |
119,953,435 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2220:Hivep3
|
UTSW |
4 |
119,591,235 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2428:Hivep3
|
UTSW |
4 |
119,955,705 (GRCm39) |
nonsense |
probably null |
|
|
R3789:Hivep3
|
UTSW |
4 |
119,955,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3917:Hivep3
|
UTSW |
4 |
119,956,624 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4366:Hivep3
|
UTSW |
4 |
119,953,286 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4436:Hivep3
|
UTSW |
4 |
119,953,120 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4504:Hivep3
|
UTSW |
4 |
119,590,990 (GRCm39) |
unclassified |
probably benign |
|
|
R4705:Hivep3
|
UTSW |
4 |
119,729,247 (GRCm39) |
intron |
probably benign |
|
|
R4713:Hivep3
|
UTSW |
4 |
119,989,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Hivep3
|
UTSW |
4 |
119,955,020 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4887:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Hivep3
|
UTSW |
4 |
119,956,114 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5204:Hivep3
|
UTSW |
4 |
119,961,053 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5594:Hivep3
|
UTSW |
4 |
119,980,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5697:Hivep3
|
UTSW |
4 |
119,954,152 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5715:Hivep3
|
UTSW |
4 |
119,953,570 (GRCm39) |
missense |
probably benign |
|
|
R5740:Hivep3
|
UTSW |
4 |
119,953,220 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5760:Hivep3
|
UTSW |
4 |
119,952,208 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5923:Hivep3
|
UTSW |
4 |
119,953,490 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5927:Hivep3
|
UTSW |
4 |
119,954,305 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6042:Hivep3
|
UTSW |
4 |
119,955,061 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6074:Hivep3
|
UTSW |
4 |
119,954,891 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6150:Hivep3
|
UTSW |
4 |
119,591,274 (GRCm39) |
nonsense |
probably null |
|
|
R6211:Hivep3
|
UTSW |
4 |
119,955,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Hivep3
|
UTSW |
4 |
119,952,137 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6451:Hivep3
|
UTSW |
4 |
119,956,105 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6531:Hivep3
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
R6651:Hivep3
|
UTSW |
4 |
119,980,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6701:Hivep3
|
UTSW |
4 |
119,951,737 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6721:Hivep3
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6796:Hivep3
|
UTSW |
4 |
119,953,558 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6864:Hivep3
|
UTSW |
4 |
119,952,085 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R6902:Hivep3
|
UTSW |
4 |
119,953,192 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7111:Hivep3
|
UTSW |
4 |
119,952,431 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7113:Hivep3
|
UTSW |
4 |
119,955,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7140:Hivep3
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7189:Hivep3
|
UTSW |
4 |
119,989,416 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7218:Hivep3
|
UTSW |
4 |
119,952,649 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7366:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7368:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7491:Hivep3
|
UTSW |
4 |
119,956,027 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7496:Hivep3
|
UTSW |
4 |
119,989,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7514:Hivep3
|
UTSW |
4 |
119,954,052 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7604:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7605:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7607:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7610:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7611:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7613:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7626:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7707:Hivep3
|
UTSW |
4 |
119,591,156 (GRCm39) |
missense |
|
|
|
R7736:Hivep3
|
UTSW |
4 |
119,952,740 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7915:Hivep3
|
UTSW |
4 |
119,954,962 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7943:Hivep3
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7972:Hivep3
|
UTSW |
4 |
119,954,711 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8093:Hivep3
|
UTSW |
4 |
119,952,632 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8111:Hivep3
|
UTSW |
4 |
119,955,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Hivep3
|
UTSW |
4 |
119,980,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Hivep3
|
UTSW |
4 |
119,956,639 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8467:Hivep3
|
UTSW |
4 |
119,952,238 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8768:Hivep3
|
UTSW |
4 |
119,989,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8890:Hivep3
|
UTSW |
4 |
119,953,657 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8902:Hivep3
|
UTSW |
4 |
119,953,937 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9022:Hivep3
|
UTSW |
4 |
119,955,304 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9336:Hivep3
|
UTSW |
4 |
119,952,400 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9606:Hivep3
|
UTSW |
4 |
119,989,786 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF019:Hivep3
|
UTSW |
4 |
119,955,467 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0062:Hivep3
|
UTSW |
4 |
119,955,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Hivep3
|
UTSW |
4 |
119,988,984 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Z1176:Hivep3
|
UTSW |
4 |
119,990,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Hivep3
|
UTSW |
4 |
119,988,975 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Hivep3
|
UTSW |
4 |
119,953,143 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCAGAAGCCTCATCGGAACATC -3'
(R):5'- AGTGACTTCTCAGGAGAGGCACAG -3'
Sequencing Primer
(F):5'- TCATCGGAACATCCCCTGAG -3'
(R):5'- TGGGCTTCACACTGTCG -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation