Mutagenetix > Incidental Mutation

Incidental Mutation 'R1565:Lmo7'

175220

Institutional Source

Beutler Lab

Gene Symbol

Lmo7

Ensembl Gene

ENSMUSG00000033060

Gene Name

LIM domain only 7

Synonyms

FBXO20, LOC380928

MMRRC Submission

039604-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.176) question?

Stock #

R1565 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

101729957-101934710 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 101887521 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Leucine at position 472 (Q472L)

Ref Sequence

ENSEMBL: ENSMUSP00000123706 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000100337] [ENSMUST00000159026] [ENSMUST00000159258] [ENSMUST00000159314] [ENSMUST00000159597]

AlphaFold

E9PYF4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000100337
AA Change: Q594L

PolyPhen 2 Score 0.853 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000097910
Gene: ENSMUSG00000033060
AA Change: Q594L

Domain	Start	End	E-Value	Type
CH	14	124	2.57e-13	SMART
low complexity region	200	211	N/A	INTRINSIC
Pfam:DUF4757	242	348	2.2e-14	PFAM
low complexity region	448	462	N/A	INTRINSIC
Pfam:DUF4757	568	735	1.8e-46	PFAM
low complexity region	861	879	N/A	INTRINSIC
low complexity region	979	991	N/A	INTRINSIC
low complexity region	1003	1015	N/A	INTRINSIC
PDZ	1047	1119	1.05e-8	SMART
coiled coil region	1222	1275	N/A	INTRINSIC
coiled coil region	1319	1411	N/A	INTRINSIC
low complexity region	1585	1596	N/A	INTRINSIC
low complexity region	1599	1617	N/A	INTRINSIC
LIM	1629	1687	6.54e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000159026
AA Change: Q361L

PolyPhen 2 Score 0.202 (Sensitivity: 0.92; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000124605
Gene: ENSMUSG00000033060
AA Change: Q361L

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC
coiled coil region	435	471	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000159258
AA Change: Q361L

PolyPhen 2 Score 0.280 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000125465
Gene: ENSMUSG00000033060
AA Change: Q361L

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000159314
AA Change: Q361L

PolyPhen 2 Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000124349
Gene: ENSMUSG00000033060
AA Change: Q361L

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC
coiled coil region	435	492	N/A	INTRINSIC
low complexity region	628	646	N/A	INTRINSIC
low complexity region	746	758	N/A	INTRINSIC
low complexity region	770	782	N/A	INTRINSIC
PDZ	814	886	1.05e-8	SMART
coiled coil region	989	1042	N/A	INTRINSIC
coiled coil region	1086	1178	N/A	INTRINSIC
low complexity region	1352	1363	N/A	INTRINSIC
low complexity region	1366	1384	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000159597
AA Change: Q472L

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000123706
Gene: ENSMUSG00000033060
AA Change: Q472L

Domain	Start	End	E-Value	Type
low complexity region	78	89	N/A	INTRINSIC
internal_repeat_1	111	141	6.96e-5	PROSPERO
internal_repeat_1	218	248	6.96e-5	PROSPERO
low complexity region	326	340	N/A	INTRINSIC
coiled coil region	546	603	N/A	INTRINSIC
low complexity region	739	757	N/A	INTRINSIC
low complexity region	857	869	N/A	INTRINSIC
low complexity region	881	893	N/A	INTRINSIC
PDZ	925	997	1.05e-8	SMART
coiled coil region	1127	1180	N/A	INTRINSIC
coiled coil region	1224	1316	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1504	1522	N/A	INTRINSIC
LIM	1534	1592	6.54e-10	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159797

Predicted Effect

probably benign
Transcript: ENSMUST00000159806

SMART Domains

Protein: ENSMUSP00000124300
Gene: ENSMUSG00000033060

Domain	Start	End	E-Value	Type
low complexity region	34	45	N/A	INTRINSIC
Pfam:DUF4757	76	225	4.5e-53	PFAM
low complexity region	351	369	N/A	INTRINSIC
low complexity region	469	481	N/A	INTRINSIC
low complexity region	493	505	N/A	INTRINSIC
PDZ	537	609	1.05e-8	SMART
internal_repeat_1	620	691	9.31e-5	PROSPERO
coiled coil region	711	764	N/A	INTRINSIC
coiled coil region	808	900	N/A	INTRINSIC
internal_repeat_1	921	976	9.31e-5	PROSPERO
low complexity region	1075	1086	N/A	INTRINSIC
low complexity region	1089	1107	N/A	INTRINSIC
LIM	1119	1177	6.54e-10	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159812

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159948

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000160876

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161668

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162091

Meta Mutation Damage Score

0.1248

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.5%
20x: 90.0%

Validation Efficiency

96% (82/85)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
PHENOTYPE: Targeted mutations in this gene result in postnatal lethality, growth defects, skeletal muscle abnormalities and retinal defects reflective of retinal degeneration. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810021J22Rik	G	A	11: 58,880,501 (GRCm38)	G270S	probably benign	Het
Abtb1	T	C	6: 88,836,554 (GRCm38)	T401A	probably benign	Het
Adamts14	A	T	10: 61,270,897 (GRCm38)	M148K	probably damaging	Het
Adcy5	A	G	16: 35,268,957 (GRCm38)	E508G	probably damaging	Het
Ankfy1	T	A	11: 72,757,318 (GRCm38)	L875H	probably damaging	Het
Cacng3	A	T	7: 122,768,401 (GRCm38)	D168V	probably damaging	Het
Clpb	G	A	7: 101,785,461 (GRCm38)	R488Q	probably benign	Het
Cpxm2	A	T	7: 132,062,145 (GRCm38)	Y350N	probably damaging	Het
D130040H23Rik	T	A	8: 69,303,160 (GRCm38)	*406R	probably null	Het
Dnah10	T	A	5: 124,829,614 (GRCm38)	D4236E	probably damaging	Het
Dpf3	T	A	12: 83,370,617 (GRCm38)	Y27F	probably damaging	Het
Esp4	T	C	17: 40,602,595 (GRCm38)	*118Q	probably null	Het
Fam222b	T	C	11: 78,154,662 (GRCm38)	S222P	possibly damaging	Het
Flnc	T	C	6: 29,455,171 (GRCm38)	V1933A	probably damaging	Het
Gem	T	C	4: 11,713,709 (GRCm38)	F282L	possibly damaging	Het
Gli2	T	C	1: 118,841,930 (GRCm38)	T631A	possibly damaging	Het
Gm13088	G	A	4: 143,655,617 (GRCm38)	Q170*	probably null	Het
Gpld1	T	A	13: 24,956,068 (GRCm38)	V116E	probably damaging	Het
Gpr176	A	G	2: 118,280,214 (GRCm38)	M188T	probably benign	Het
Grk5	T	C	19: 61,089,972 (GRCm38)	V489A	probably damaging	Het
H2-Ke6	C	T	17: 34,027,495 (GRCm38)	V105I	possibly damaging	Het
Hpdl	T	C	4: 116,820,883 (GRCm38)	N127S	probably damaging	Het
Id4	G	T	13: 48,262,294 (GRCm38)	V151L	possibly damaging	Het
Kcnh8	G	T	17: 52,956,881 (GRCm38)	G802V	probably benign	Het
Lamc1	C	A	1: 153,242,743 (GRCm38)	S894I	probably benign	Het
Larp1b	A	G	3: 40,972,384 (GRCm38)	N184S	probably damaging	Het
Lhx1	A	T	11: 84,519,821 (GRCm38)	S226T	probably benign	Het
Mog	G	C	17: 37,017,582 (GRCm38)	N152K	possibly damaging	Het
Mttp	A	G	3: 138,116,405 (GRCm38)		probably null	Het
Mycbp2	A	G	14: 103,252,509 (GRCm38)	V953A	possibly damaging	Het
Myo3a	A	T	2: 22,340,280 (GRCm38)	Y509F	probably damaging	Het
Myo9b	A	G	8: 71,315,192 (GRCm38)	N303S	possibly damaging	Het
Nek3	T	C	8: 22,132,201 (GRCm38)		probably null	Het
Nlrc4	A	T	17: 74,441,931 (GRCm38)	D771E	probably benign	Het
Nup160	A	T	2: 90,722,061 (GRCm38)	N1127I	possibly damaging	Het
Oas1h	A	T	5: 120,862,600 (GRCm38)	N91I	probably damaging	Het
Olfr1225	A	T	2: 89,170,627 (GRCm38)	V195D	probably benign	Het
Olfr1226	G	T	2: 89,193,883 (GRCm38)	S50R	probably damaging	Het
Olfr1342	T	A	4: 118,690,192 (GRCm38)	N87Y	probably damaging	Het
Parp4	T	C	14: 56,589,872 (GRCm38)		probably benign	Het
Pi4ka	G	A	16: 17,281,900 (GRCm38)	C96Y	probably null	Het
Pira2	A	T	7: 3,844,549 (GRCm38)	F47Y	probably damaging	Het
Pkhd1	C	A	1: 20,347,457 (GRCm38)	G2490V	probably damaging	Het
Plekhg1	C	T	10: 3,940,526 (GRCm38)	T394I	probably damaging	Het
Psmd1	T	C	1: 86,091,997 (GRCm38)		probably benign	Het
Rab3ip	A	T	10: 116,939,223 (GRCm38)	C77S	probably benign	Het
Reln	A	T	5: 21,925,213 (GRCm38)	M2700K	probably benign	Het
Rfx1	A	G	8: 84,073,946 (GRCm38)	T59A	probably benign	Het
Ric8b	G	T	10: 84,980,099 (GRCm38)	V405L	probably benign	Het
Rufy3	G	T	5: 88,640,632 (GRCm38)	A479S	probably damaging	Het
Sardh	A	T	2: 27,242,719 (GRCm38)	Y166N	probably damaging	Het
Slamf6	T	G	1: 171,934,408 (GRCm38)	V132G	possibly damaging	Het
Slc12a3	T	G	8: 94,345,877 (GRCm38)	H674Q	possibly damaging	Het
Sned1	G	A	1: 93,281,654 (GRCm38)	V830M	possibly damaging	Het
Srsf9	A	G	5: 115,327,370 (GRCm38)	N21S	possibly damaging	Het
Stkld1	A	T	2: 26,950,090 (GRCm38)	T391S	probably benign	Het
Sumf2	C	A	5: 129,859,914 (GRCm38)	N230K	probably damaging	Het
Tbc1d22a	T	C	15: 86,235,569 (GRCm38)	V22A	possibly damaging	Het
Thsd7b	T	A	1: 129,596,041 (GRCm38)	S194T	possibly damaging	Het
Tmem27	A	G	X: 164,118,234 (GRCm38)	D184G	possibly damaging	Het
Tnn	T	A	1: 160,097,265 (GRCm38)	Y1173F	probably damaging	Het
Top2a	A	G	11: 99,001,054 (GRCm38)	F1122L	probably damaging	Het
Trappc9	G	A	15: 73,025,967 (GRCm38)	R377W	probably damaging	Het
Trim39	G	A	17: 36,268,854 (GRCm38)	R70W	probably damaging	Het
Ttn	G	A	2: 76,794,261 (GRCm38)	T15289I	probably damaging	Het
Ugt2b38	A	T	5: 87,411,914 (GRCm38)	V373E	probably damaging	Het
Usp54	A	G	14: 20,607,159 (GRCm38)	S24P	probably damaging	Het
Vmn2r27	C	T	6: 124,231,634 (GRCm38)	G51S	probably benign	Het
Xylt2	C	T	11: 94,667,594 (GRCm38)	A579T	probably benign	Het
Zbtb21	A	G	16: 97,952,427 (GRCm38)	S247P	probably benign	Het
Zc3h7b	C	T	15: 81,777,088 (GRCm38)	P376L	probably benign	Het
Zfp251	C	T	15: 76,853,039 (GRCm38)	R613K	possibly damaging	Het
Zfp251	T	A	15: 76,853,038 (GRCm38)	R613S	probably damaging	Het
Zfp91	T	C	19: 12,779,075 (GRCm38)	D135G	probably benign	Het

Other mutations in Lmo7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00569:Lmo7	APN	14	101,887,051 (GRCm38)	missense	probably damaging	0.99
IGL00733:Lmo7	APN	14	101,915,702 (GRCm38)	missense	probably damaging	1.00
IGL00778:Lmo7	APN	14	101,910,885 (GRCm38)	splice site	probably benign
IGL01014:Lmo7	APN	14	101,920,557 (GRCm38)	splice site	probably benign
IGL01401:Lmo7	APN	14	101,794,277 (GRCm38)	nonsense	probably null
IGL01550:Lmo7	APN	14	101,926,140 (GRCm38)	utr 3 prime	probably benign
IGL01570:Lmo7	APN	14	101,902,371 (GRCm38)	critical splice donor site	probably null
IGL01602:Lmo7	APN	14	101,910,756 (GRCm38)	splice site	probably benign
IGL01605:Lmo7	APN	14	101,910,756 (GRCm38)	splice site	probably benign
IGL02012:Lmo7	APN	14	101,888,716 (GRCm38)	intron	probably benign
IGL02145:Lmo7	APN	14	101,902,223 (GRCm38)	missense	probably benign	0.00
IGL02236:Lmo7	APN	14	101,926,088 (GRCm38)	splice site	probably benign
IGL02318:Lmo7	APN	14	101,900,066 (GRCm38)	splice site	probably benign
IGL02345:Lmo7	APN	14	101,887,473 (GRCm38)	missense	probably damaging	1.00
IGL02498:Lmo7	APN	14	101,807,482 (GRCm38)	missense	probably benign	0.01
IGL02583:Lmo7	APN	14	101,933,924 (GRCm38)	utr 3 prime	probably benign
IGL02670:Lmo7	APN	14	101,880,980 (GRCm38)	missense	probably damaging	1.00
IGL02694:Lmo7	APN	14	101,887,170 (GRCm38)	missense	probably damaging	1.00
IGL03026:Lmo7	APN	14	101,929,333 (GRCm38)	utr 3 prime	probably benign
IGL03062:Lmo7	APN	14	101,912,079 (GRCm38)	missense	possibly damaging	0.66
IGL03068:Lmo7	APN	14	101,875,492 (GRCm38)	unclassified	probably benign
IGL03178:Lmo7	APN	14	101,929,260 (GRCm38)	nonsense	probably null
IGL03279:Lmo7	APN	14	101,900,508 (GRCm38)	missense	probably benign	0.30
PIT4458001:Lmo7	UTSW	14	101,887,487 (GRCm38)	nonsense	probably null
R0029:Lmo7	UTSW	14	101,933,921 (GRCm38)	utr 3 prime	probably benign
R0112:Lmo7	UTSW	14	101,887,193 (GRCm38)	nonsense	probably null
R0345:Lmo7	UTSW	14	101,876,877 (GRCm38)	missense	probably damaging	1.00
R0372:Lmo7	UTSW	14	101,918,053 (GRCm38)	splice site	probably benign
R0393:Lmo7	UTSW	14	101,900,456 (GRCm38)	missense	probably benign
R0514:Lmo7	UTSW	14	101,896,559 (GRCm38)	missense	probably damaging	1.00
R0514:Lmo7	UTSW	14	101,887,173 (GRCm38)	missense	probably damaging	1.00
R0526:Lmo7	UTSW	14	101,900,560 (GRCm38)	missense	probably damaging	1.00
R0615:Lmo7	UTSW	14	101,876,859 (GRCm38)	nonsense	probably null
R0900:Lmo7	UTSW	14	101,887,188 (GRCm38)	missense	probably damaging	1.00
R0961:Lmo7	UTSW	14	101,794,269 (GRCm38)	missense	probably benign	0.00
R0964:Lmo7	UTSW	14	101,920,567 (GRCm38)	splice site	probably benign
R1078:Lmo7	UTSW	14	101,920,474 (GRCm38)	splice site	probably benign
R1252:Lmo7	UTSW	14	101,900,583 (GRCm38)	missense	probably damaging	1.00
R1527:Lmo7	UTSW	14	101,876,828 (GRCm38)	missense	probably damaging	1.00
R1537:Lmo7	UTSW	14	101,929,264 (GRCm38)	utr 3 prime	probably benign
R1637:Lmo7	UTSW	14	101,880,832 (GRCm38)	missense	probably damaging	1.00
R1943:Lmo7	UTSW	14	101,902,302 (GRCm38)	missense	probably damaging	1.00
R1967:Lmo7	UTSW	14	101,900,215 (GRCm38)	missense	probably benign	0.36
R2002:Lmo7	UTSW	14	101,887,061 (GRCm38)	missense	probably benign	0.13
R2057:Lmo7	UTSW	14	101,887,178 (GRCm38)	missense	probably damaging	1.00
R2131:Lmo7	UTSW	14	101,900,238 (GRCm38)	missense	probably damaging	0.99
R2153:Lmo7	UTSW	14	101,920,515 (GRCm38)	utr 3 prime	probably benign
R2257:Lmo7	UTSW	14	101,900,130 (GRCm38)	missense	probably damaging	1.00
R2355:Lmo7	UTSW	14	101,888,685 (GRCm38)	missense	probably damaging	1.00
R2356:Lmo7	UTSW	14	101,886,945 (GRCm38)	missense	probably damaging	1.00
R2898:Lmo7	UTSW	14	101,876,914 (GRCm38)	missense	possibly damaging	0.93
R3847:Lmo7	UTSW	14	101,922,095 (GRCm38)	critical splice acceptor site	probably null
R3848:Lmo7	UTSW	14	101,922,095 (GRCm38)	critical splice acceptor site	probably null
R3849:Lmo7	UTSW	14	101,922,095 (GRCm38)	critical splice acceptor site	probably null
R3916:Lmo7	UTSW	14	101,929,342 (GRCm38)	utr 3 prime	probably benign
R4050:Lmo7	UTSW	14	101,902,277 (GRCm38)	nonsense	probably null
R4326:Lmo7	UTSW	14	101,900,074 (GRCm38)	missense	possibly damaging	0.93
R4357:Lmo7	UTSW	14	101,887,655 (GRCm38)	missense	probably null	1.00
R4571:Lmo7	UTSW	14	101,887,594 (GRCm38)	missense	probably damaging	0.96
R4658:Lmo7	UTSW	14	101,886,957 (GRCm38)	missense	probably damaging	1.00
R4857:Lmo7	UTSW	14	101,887,348 (GRCm38)	splice site	probably null
R5006:Lmo7	UTSW	14	101,926,237 (GRCm38)	utr 3 prime	probably benign
R5528:Lmo7	UTSW	14	101,902,086 (GRCm38)	missense	probably damaging	1.00
R5588:Lmo7	UTSW	14	101,896,590 (GRCm38)	splice site	probably null
R5643:Lmo7	UTSW	14	101,929,336 (GRCm38)	utr 3 prime	probably benign
R5644:Lmo7	UTSW	14	101,929,336 (GRCm38)	utr 3 prime	probably benign
R5650:Lmo7	UTSW	14	101,898,674 (GRCm38)	missense	probably damaging	1.00
R5737:Lmo7	UTSW	14	101,887,236 (GRCm38)	missense	probably damaging	1.00
R5832:Lmo7	UTSW	14	101,884,213 (GRCm38)	missense	probably damaging	1.00
R5966:Lmo7	UTSW	14	101,900,502 (GRCm38)	missense	possibly damaging	0.92
R6026:Lmo7	UTSW	14	101,880,990 (GRCm38)	missense	probably benign	0.04
R6072:Lmo7	UTSW	14	101,929,336 (GRCm38)	utr 3 prime	probably benign
R6158:Lmo7	UTSW	14	101,900,137 (GRCm38)	missense	probably benign	0.03
R6246:Lmo7	UTSW	14	101,918,700 (GRCm38)	missense	probably damaging	1.00
R6335:Lmo7	UTSW	14	101,900,636 (GRCm38)	missense	probably damaging	1.00
R6620:Lmo7	UTSW	14	101,875,452 (GRCm38)	missense	probably benign	0.29
R6658:Lmo7	UTSW	14	101,910,845 (GRCm38)	missense	possibly damaging	0.84
R6917:Lmo7	UTSW	14	101,918,010 (GRCm38)	missense	probably damaging	1.00
R7064:Lmo7	UTSW	14	101,884,179 (GRCm38)	missense	probably damaging	1.00
R7072:Lmo7	UTSW	14	101,898,700 (GRCm38)	critical splice donor site	probably null
R7121:Lmo7	UTSW	14	101,887,035 (GRCm38)	missense	probably damaging	1.00
R7136:Lmo7	UTSW	14	101,920,539 (GRCm38)	missense	unknown
R7196:Lmo7	UTSW	14	101,896,500 (GRCm38)	missense	possibly damaging	0.75
R7228:Lmo7	UTSW	14	101,896,535 (GRCm38)	missense	probably damaging	0.99
R7337:Lmo7	UTSW	14	101,884,204 (GRCm38)	missense	probably damaging	0.98
R7341:Lmo7	UTSW	14	101,885,512 (GRCm38)	missense	probably benign	0.30
R7408:Lmo7	UTSW	14	101,880,953 (GRCm38)	missense	probably damaging	1.00
R7432:Lmo7	UTSW	14	101,902,115 (GRCm38)	missense	probably benign	0.42
R7470:Lmo7	UTSW	14	101,900,604 (GRCm38)	missense	possibly damaging	0.83
R7506:Lmo7	UTSW	14	101,919,609 (GRCm38)	missense	unknown
R7559:Lmo7	UTSW	14	101,887,226 (GRCm38)	nonsense	probably null
R7565:Lmo7	UTSW	14	101,885,301 (GRCm38)	missense	probably damaging	0.98
R7788:Lmo7	UTSW	14	101,898,576 (GRCm38)	missense	possibly damaging	0.64
R8095:Lmo7	UTSW	14	101,887,419 (GRCm38)	missense	possibly damaging	0.88
R8100:Lmo7	UTSW	14	101,900,463 (GRCm38)	missense	probably benign	0.33
R8121:Lmo7	UTSW	14	101,926,300 (GRCm38)	missense	unknown
R8308:Lmo7	UTSW	14	101,902,371 (GRCm38)	critical splice donor site	probably null
R8371:Lmo7	UTSW	14	101,887,008 (GRCm38)	missense	possibly damaging	0.95
R8403:Lmo7	UTSW	14	101,902,364 (GRCm38)	missense	probably benign	0.03
R8690:Lmo7	UTSW	14	101,931,208 (GRCm38)	missense	unknown
R8778:Lmo7	UTSW	14	101,919,219 (GRCm38)	missense	probably benign	0.24
R8778:Lmo7	UTSW	14	101,912,067 (GRCm38)	missense	probably damaging	0.98
R8822:Lmo7	UTSW	14	101,884,174 (GRCm38)	missense	probably damaging	1.00
R8849:Lmo7	UTSW	14	101,926,107 (GRCm38)	missense	unknown
R8923:Lmo7	UTSW	14	101,900,243 (GRCm38)	missense	probably benign	0.31
R9006:Lmo7	UTSW	14	101,917,636 (GRCm38)	small deletion	probably benign
R9135:Lmo7	UTSW	14	101,880,861 (GRCm38)	missense	probably damaging	1.00
R9154:Lmo7	UTSW	14	101,885,307 (GRCm38)	missense	probably damaging	0.99
R9178:Lmo7	UTSW	14	101,807,470 (GRCm38)	nonsense	probably null
R9375:Lmo7	UTSW	14	101,898,687 (GRCm38)	missense	probably damaging	0.99
R9428:Lmo7	UTSW	14	101,917,640 (GRCm38)	missense	probably damaging	0.99
R9488:Lmo7	UTSW	14	101,885,347 (GRCm38)	missense	possibly damaging	0.85
R9493:Lmo7	UTSW	14	101,900,471 (GRCm38)	missense	probably benign	0.01
R9594:Lmo7	UTSW	14	101,918,700 (GRCm38)	missense	probably null	0.98
R9674:Lmo7	UTSW	14	101,840,904 (GRCm38)	missense	probably damaging	1.00
R9736:Lmo7	UTSW	14	101,920,493 (GRCm38)	missense	unknown
X0066:Lmo7	UTSW	14	101,887,461 (GRCm38)	missense	probably damaging	1.00
X0067:Lmo7	UTSW	14	101,886,933 (GRCm38)	splice site	probably null
Z1176:Lmo7	UTSW	14	101,919,281 (GRCm38)	missense	probably benign	0.00
Z1176:Lmo7	UTSW	14	101,884,306 (GRCm38)	missense	probably damaging	0.99
Z1176:Lmo7	UTSW	14	101,929,228 (GRCm38)	missense	unknown
Z1176:Lmo7	UTSW	14	101,919,443 (GRCm38)	missense	unknown
Z1177:Lmo7	UTSW	14	101,898,557 (GRCm38)	missense	probably damaging	1.00
Z1177:Lmo7	UTSW	14	101,896,518 (GRCm38)	missense	possibly damaging	0.96

Predicted Primers

PCR Primer
(F):5'- CGCAGGATTCCAGCTCAGAAGAAAG -3'
(R):5'- GGATGCTTCAAAACGGCACACAG -3'

Sequencing Primer
(F):5'- AAAGAAGTGCCCCTTTCTGG -3'
(R):5'- TTTCCCCAATAAGGAAAGTTACAC -3'

Posted On

2014-04-24