Mutagenetix > Incidental Mutation

Incidental Mutation 'R1613:Gm5885'

176928

Institutional Source

Beutler Lab

Gene Symbol

Gm5885

Ensembl Gene

ENSMUSG00000095412

Gene Name

predicted gene 5885

Synonyms

MMRRC Submission

039650-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R1613 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

133529189-133532762 bp(+) (GRCm38)

Type of Mutation

exon

DNA Base Change (assembly)

G to A at 133531242 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000178578

SMART Domains

Protein: ENSMUSP00000136262
Gene: ENSMUSG00000095412

Domain	Start	End	E-Value	Type
Pfam:Pro-rich	1	166	2.5e-13	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000203357

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.7%
20x: 90.5%

Validation Efficiency

82% (69/84)

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agrp	G	T	8: 105,566,835	T106K	probably damaging	Het
Aldh3a1	A	T	11: 61,214,551	D161V	probably damaging	Het
Aloxe3	A	G	11: 69,130,046	D199G	possibly damaging	Het
Amfr	T	A	8: 93,999,226	M176L	probably benign	Het
Amigo1	A	T	3: 108,188,220	E345V	probably benign	Het
Atp13a3	T	C	16: 30,332,300	Y1064C	probably damaging	Het
AU019823	T	C	9: 50,607,805	K169R	probably damaging	Het
Brd7	A	T	8: 88,346,950	C271S	probably benign	Het
Bub1b	T	A	2: 118,639,741		probably null	Het
Ccdc146	T	A	5: 21,294,524	I887F	probably damaging	Het
Ceacam14	T	C	7: 17,814,048		probably benign	Het
Cntn1	T	A	15: 92,245,990	V278E	possibly damaging	Het
Col6a6	A	C	9: 105,732,211		probably null	Het
Cspp1	C	T	1: 10,133,241	R1016C	probably damaging	Het
Cyp2c39	A	G	19: 39,539,011	Y267C	probably damaging	Het
Cyp2c67	C	T	19: 39,626,199	V295I	probably benign	Het
Cyp2d40	T	C	15: 82,761,439	T122A	unknown	Het
Dmxl2	A	G	9: 54,382,027	I2541T	probably benign	Het
Eif3e	G	A	15: 43,250,224	A438V	possibly damaging	Het
Fam178b	C	A	1: 36,600,192	W342L	probably benign	Het
Fam45a	T	A	19: 60,822,325	V171D	possibly damaging	Het
Fam78a	G	T	2: 32,069,569	N176K	probably damaging	Het
Ghrhr	A	T	6: 55,379,697	K93M	probably damaging	Het
Gm1527	T	A	3: 28,898,853		probably null	Het
Gm1553	G	A	10: 82,492,596		probably benign	Het
Gm8674	G	A	13: 49,902,438		noncoding transcript	Het
Hoxc6	C	T	15: 103,009,585		probably benign	Het
Ino80	T	C	2: 119,392,867	T1189A	probably damaging	Het
Iqgap1	T	C	7: 80,768,457	E55G	probably damaging	Het
Kcnh2	G	A	5: 24,322,762		probably benign	Het
Lama1	G	A	17: 67,807,923	G2356S	probably benign	Het
Mdfic	T	A	6: 15,799,590		probably null	Het
Me3	T	C	7: 89,786,420		probably benign	Het
Mmadhc	T	C	2: 50,280,326	D258G	probably damaging	Het
Nfe2	T	C	15: 103,249,129	D145G	probably damaging	Het
Olfr1039	A	T	2: 86,131,063	L200Q	probably damaging	Het
Olfr1200	T	C	2: 88,767,805	N170S	probably damaging	Het
Olfr1377	T	A	11: 50,985,218	N172K	probably damaging	Het
Olfr1391	A	G	11: 49,327,693	Y94C	probably damaging	Het
Olfr1404	C	T	1: 173,215,867	T72I	probably benign	Het
Olfr352	A	C	2: 36,870,393	I276L	possibly damaging	Het
Olfr728	A	C	14: 50,140,294	L115R	probably damaging	Het
P4ha3	A	T	7: 100,313,250	D405V	possibly damaging	Het
Palmd	T	C	3: 116,923,504	D448G	probably damaging	Het
Pclo	T	C	5: 14,679,132		probably benign	Het
Pcsk6	A	G	7: 65,910,311		probably benign	Het
Pidd1	T	C	7: 141,440,777	E469G	probably damaging	Het
Ptpn13	A	G	5: 103,536,871	D875G	possibly damaging	Het
Rasgrf2	A	G	13: 91,902,621	L886P	probably damaging	Het
Scrib	G	A	15: 76,048,542	R1454C	probably damaging	Het
Slc24a1	A	G	9: 64,948,696	S310P	unknown	Het
Slc44a5	A	G	3: 154,257,714		probably null	Het
Snx4	T	G	16: 33,286,046	M283R	probably damaging	Het
Snx7	A	T	3: 117,829,573		probably benign	Het
Stk19	A	T	17: 34,824,598	L212H	probably damaging	Het
Sult2a4	T	C	7: 13,989,495	K32E	probably damaging	Het
Tfrc	T	A	16: 32,623,375	Y473N	probably damaging	Het
Tlr2	C	G	3: 83,837,353	L474F	probably damaging	Het
Tnfrsf4	T	A	4: 156,016,162	F213I	probably benign	Het
Trim9	A	T	12: 70,248,395	I651N	probably damaging	Het
Vmn1r84	T	A	7: 12,362,533	I78L	possibly damaging	Het
Vmn2r77	T	C	7: 86,811,148	Y561H	probably damaging	Het
Vmn2r95	A	G	17: 18,440,639		probably benign	Het
Zfp11	T	C	5: 129,658,367	N10S	probably benign	Het
Zfp81	A	T	17: 33,334,783	H352Q	probably damaging	Het
Zscan5b	T	A	7: 6,230,375	L66Q	probably damaging	Het

Other mutations in Gm5885

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01808:Gm5885	APN	6	133531218	exon	noncoding transcript
IGL02026:Gm5885	APN	6	133531328	exon	noncoding transcript
IGL02364:Gm5885	APN	6	133530129	splice site	noncoding transcript
R2141:Gm5885	UTSW	6	133529275	exon	noncoding transcript
R4352:Gm5885	UTSW	6	133531189	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- AGAGTTAGGTCCTTCTGCTGCTGC -3'
(R):5'- GAGCTATGTTACTCAGGGGCACAAG -3'

Sequencing Primer
(F):5'- CTGCTGCTGCTGCAAATATAG -3'
(R):5'- TTACTCAGGGGCACAAGTACATTG -3'

Posted On

2014-04-24