Mutagenetix > Incidental Mutation

Incidental Mutation 'R1584:Tep1'

177377

Institutional Source

Beutler Lab

Gene Symbol

Tep1

Ensembl Gene

ENSMUSG00000006281

Gene Name

telomerase associated protein 1

Synonyms

Tp1

MMRRC Submission

039621-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1584 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

50824059-50870560 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 50866037 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 265 (N265K)

Ref Sequence

ENSEMBL: ENSMUSP00000006444 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000006444]

AlphaFold

P97499

Predicted Effect

probably damaging
Transcript: ENSMUST00000006444
AA Change: N265K

PolyPhen 2 Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000006444
Gene: ENSMUSG00000006281
AA Change: N265K

Domain	Start	End	E-Value	Type
Pfam:TEP1_N	1	29	2.8e-20	PFAM
Pfam:TEP1_N	31	59	1.4e-20	PFAM
Pfam:TEP1_N	61	89	3.1e-20	PFAM
Pfam:TEP1_N	91	119	3e-20	PFAM
low complexity region	195	207	N/A	INTRINSIC
low complexity region	211	229	N/A	INTRINSIC
Pfam:TROVE	230	685	3.2e-136	PFAM
Pfam:DUF4062	909	1020	2.4e-22	PFAM
Pfam:NACHT	1171	1346	9.2e-38	PFAM
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1622	1641	N/A	INTRINSIC
WD40	1673	1711	2.98e-1	SMART
WD40	1714	1752	5.33e0	SMART
WD40	1755	1794	1.52e-4	SMART
WD40	1797	1835	3.27e-4	SMART
WD40	1838	1877	3.09e-1	SMART
WD40	1880	1919	2.24e-2	SMART
WD40	1925	1962	4.95e0	SMART
WD40	1968	2003	2.29e1	SMART
WD40	2008	2045	1.72e0	SMART
WD40	2058	2097	3.89e-11	SMART
WD40	2103	2142	3.93e-7	SMART
WD40	2145	2182	4.38e-5	SMART
WD40	2184	2232	1.24e0	SMART
WD40	2235	2273	1.14e-3	SMART
WD40	2275	2315	4.46e-1	SMART
Blast:WD40	2316	2353	4e-12	BLAST
WD40	2546	2583	6.79e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181482

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000181697

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227103

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227207

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227351

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228078

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000228254

Meta Mutation Damage Score

0.6467

Coding Region Coverage

1x: 99.0%
3x: 98.1%
10x: 95.6%
20x: 90.2%

Validation Efficiency

99% (106/107)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
PHENOTYPE: Mice homozygous for a disruption in this gene show no obvious phenotype. No changes are seen in telomerase activity or telomere length. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 93 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abhd15	C	T	11: 77,515,410 (GRCm38)	A71V	probably damaging	Het
Ager	A	G	17: 34,600,718 (GRCm38)	E357G	probably damaging	Het
Akap13	T	C	7: 75,729,049 (GRCm38)	S2095P	possibly damaging	Het
Ampd2	T	C	3: 108,080,337 (GRCm38)		probably null	Het
Arrdc1	T	C	2: 24,925,795 (GRCm38)	I398V	probably benign	Het
Ash1l	T	C	3: 89,052,065 (GRCm38)	Y2250H	probably damaging	Het
BC005561	T	A	5: 104,518,257 (GRCm38)	I215N	probably damaging	Het
Brca2	G	A	5: 150,552,258 (GRCm38)	A2478T	probably damaging	Het
Btrc	T	A	19: 45,513,382 (GRCm38)		probably benign	Het
C8g	C	T	2: 25,500,216 (GRCm38)	A6T	probably benign	Het
Cdc123	T	A	2: 5,803,977 (GRCm38)		probably null	Het
Cilp	G	A	9: 65,279,715 (GRCm38)	G1031S	probably damaging	Het
Cldn5	G	A	16: 18,777,477 (GRCm38)	G161D	probably damaging	Het
Cndp2	G	A	18: 84,677,315 (GRCm38)		probably benign	Het
Cntnap1	C	A	11: 101,180,360 (GRCm38)	F366L	probably damaging	Het
Corin	C	T	5: 72,302,790 (GRCm38)		probably null	Het
Ctdspl2	G	A	2: 122,003,929 (GRCm38)	R332K	probably benign	Het
Dido1	G	A	2: 180,662,328 (GRCm38)	P1261L	probably damaging	Het
Dopey1	A	T	9: 86,548,172 (GRCm38)	R2200*	probably null	Het
Dtx3l	G	A	16: 35,932,728 (GRCm38)	L503F	probably damaging	Het
Dysf	A	G	6: 84,067,047 (GRCm38)	K259R	probably benign	Het
Enpep	T	A	3: 129,319,448 (GRCm38)	T203S	probably damaging	Het
Epha2	T	A	4: 141,322,047 (GRCm38)		probably null	Het
Fam20b	T	C	1: 156,686,188 (GRCm38)		probably benign	Het
Fbln7	A	G	2: 128,877,429 (GRCm38)	T49A	probably benign	Het
Fgf14	T	A	14: 124,676,539 (GRCm38)	K60M	probably benign	Het
Fhad1	T	C	4: 141,985,511 (GRCm38)	I206V	probably benign	Het
Figla	A	G	6: 86,020,782 (GRCm38)	E164G	probably benign	Het
Gimap4	C	A	6: 48,691,282 (GRCm38)	Q196K	probably benign	Het
Glcci1	C	T	6: 8,537,964 (GRCm38)	T6I	probably damaging	Het
Gm6583	C	T	5: 112,354,764 (GRCm38)	G358D	probably benign	Het
Grk4	T	C	5: 34,694,750 (GRCm38)	S113P	probably benign	Het
Hectd3	G	A	4: 116,996,566 (GRCm38)	E220K	probably damaging	Het
Hecw1	A	G	13: 14,340,743 (GRCm38)		probably null	Het
Helz2	G	A	2: 181,236,297 (GRCm38)	P903S	probably damaging	Het
Hydin	T	C	8: 110,580,815 (GRCm38)	V3942A	probably benign	Het
Irs1	G	T	1: 82,289,444 (GRCm38)	H350Q	probably benign	Het
Kdm1b	G	A	13: 47,064,054 (GRCm38)	E46K	probably damaging	Het
Klf11	A	G	12: 24,655,305 (GRCm38)	N253D	probably damaging	Het
Klhl23	T	C	2: 69,833,888 (GRCm38)	I527T	probably damaging	Het
Lars	G	A	18: 42,210,050 (GRCm38)	R1101C	probably damaging	Het
Lcn4	G	A	2: 26,668,576 (GRCm38)	P166L	probably damaging	Het
Letmd1	T	A	15: 100,472,542 (GRCm38)		probably null	Het
Lilra6	T	A	7: 3,912,662 (GRCm38)	D358V	probably damaging	Het
Mmrn2	A	G	14: 34,375,685 (GRCm38)	D24G	probably benign	Het
Mpp5	A	G	12: 78,829,727 (GRCm38)	I482V	probably benign	Het
Mroh2b	G	T	15: 4,925,684 (GRCm38)	D720Y	probably damaging	Het
Mrps35	C	T	6: 147,055,984 (GRCm38)	T169M	probably damaging	Het
Muc4	G	A	16: 32,753,595 (GRCm38)	G1157D	probably benign	Het
Naga	T	A	15: 82,334,788 (GRCm38)	M237L	probably null	Het
Nfu1	G	A	6: 87,020,809 (GRCm38)	E225K	probably damaging	Het
Nin	A	T	12: 70,042,669 (GRCm38)	L1324Q	probably benign	Het
Oc90	T	A	15: 65,897,720 (GRCm38)	Y96F	probably damaging	Het
Olfr1029	T	A	2: 85,975,995 (GRCm38)	F251I	probably damaging	Het
Olfr1253	C	T	2: 89,752,267 (GRCm38)	C187Y	probably damaging	Het
Olfr1471	T	C	19: 13,445,659 (GRCm38)	Y216H	probably damaging	Het
Olfr25	G	A	9: 38,330,131 (GRCm38)	M181I	possibly damaging	Het
Olfr522	A	G	7: 140,162,203 (GRCm38)	V249A	probably damaging	Het
Orc4	A	T	2: 48,909,494 (GRCm38)	C324S	possibly damaging	Het
Pdzrn4	T	C	15: 92,770,537 (GRCm38)	S857P	probably benign	Het
Plec	C	T	15: 76,185,908 (GRCm38)	E1000K	possibly damaging	Het
Plvap	A	T	8: 71,508,481 (GRCm38)	V149D	probably benign	Het
Pm20d2	A	T	4: 33,174,772 (GRCm38)	N371K	probably damaging	Het
Ppp2r5d	A	G	17: 46,684,684 (GRCm38)	Y480H	probably benign	Het
Prkd1	A	T	12: 50,425,515 (GRCm38)	V205E	probably damaging	Het
R3hdm2	A	G	10: 127,476,690 (GRCm38)	I434V	probably benign	Het
Rel	T	A	11: 23,745,546 (GRCm38)	T246S	probably damaging	Het
Rnf215	T	A	11: 4,136,719 (GRCm38)	V172E	probably damaging	Het
Scara3	T	C	14: 65,921,104 (GRCm38)	D485G	probably damaging	Het
Sec16a	A	T	2: 26,431,157 (GRCm38)	Y1308N	probably damaging	Het
Sis	A	T	3: 72,932,060 (GRCm38)	D824E	possibly damaging	Het
Slc27a4	T	A	2: 29,811,190 (GRCm38)	V331E	probably damaging	Het
Srebf1	C	T	11: 60,200,702 (GRCm38)	R999H	probably benign	Het
St3gal3	A	C	4: 118,107,662 (GRCm38)	M1R	probably null	Het
Tapbp	C	T	17: 33,919,940 (GRCm38)		probably null	Het
Tln2	T	A	9: 67,296,414 (GRCm38)	N470I	probably damaging	Het
Trim43a	G	T	9: 88,588,158 (GRCm38)	W339L	probably damaging	Het
Ttc22	T	C	4: 106,622,780 (GRCm38)	F77S	probably damaging	Het
Ttc8	A	G	12: 98,920,764 (GRCm38)	E32G	probably benign	Het
Uhmk1	A	T	1: 170,208,653 (GRCm38)		probably null	Het
Usp17lc	A	G	7: 103,418,941 (GRCm38)	H481R	possibly damaging	Het
Vamp8	G	A	6: 72,385,634 (GRCm38)	T35M	probably damaging	Het
Vill	A	G	9: 119,065,586 (GRCm38)	Y53C	probably damaging	Het
Vmn1r222	A	T	13: 23,232,762 (GRCm38)	S94T	probably damaging	Het
Vmn2r93	A	G	17: 18,305,151 (GRCm38)	Y357C	possibly damaging	Het
Vps13c	T	A	9: 67,893,112 (GRCm38)	V536D	possibly damaging	Het
Vrtn	G	A	12: 84,650,081 (GRCm38)	C535Y	probably damaging	Het
Vwa3a	A	G	7: 120,768,165 (GRCm38)	Y181C	probably damaging	Het
Wfikkn2	G	A	11: 94,238,895 (GRCm38)	T140I	probably damaging	Het
Ykt6	T	A	11: 5,962,349 (GRCm38)	F101I	probably damaging	Het
Zfp277	C	T	12: 40,378,826 (GRCm38)	G174D	probably benign	Het
Zfp638	A	G	6: 83,978,065 (GRCm38)		probably null	Het
Zzef1	C	T	11: 72,924,679 (GRCm38)	P2942S	probably damaging	Het

Other mutations in Tep1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00482:Tep1	APN	14	50,843,184 (GRCm38)	missense	probably damaging	1.00
IGL00490:Tep1	APN	14	50,833,473 (GRCm38)	missense	probably damaging	0.97
IGL01114:Tep1	APN	14	50,850,639 (GRCm38)	missense	probably damaging	0.98
IGL01294:Tep1	APN	14	50,829,657 (GRCm38)	splice site	probably benign
IGL01902:Tep1	APN	14	50,866,091 (GRCm38)	splice site	probably benign
IGL01910:Tep1	APN	14	50,844,112 (GRCm38)	missense	probably benign	0.06
IGL01925:Tep1	APN	14	50,824,498 (GRCm38)	unclassified	probably benign
IGL01965:Tep1	APN	14	50,863,495 (GRCm38)	splice site	probably benign
IGL02071:Tep1	APN	14	50,834,049 (GRCm38)	missense	possibly damaging	0.93
IGL02124:Tep1	APN	14	50,854,124 (GRCm38)	unclassified	probably benign
IGL02189:Tep1	APN	14	50,826,826 (GRCm38)	missense	probably benign
IGL02252:Tep1	APN	14	50,830,255 (GRCm38)	missense	possibly damaging	0.93
IGL02299:Tep1	APN	14	50,840,671 (GRCm38)	missense	probably damaging	0.99
IGL02343:Tep1	APN	14	50,829,247 (GRCm38)	missense	probably damaging	0.99
IGL02423:Tep1	APN	14	50,844,620 (GRCm38)	missense	possibly damaging	0.53
IGL02537:Tep1	APN	14	50,836,113 (GRCm38)	missense	probably damaging	0.96
IGL02601:Tep1	APN	14	50,833,478 (GRCm38)	nonsense	probably null
IGL02941:Tep1	APN	14	50,866,037 (GRCm38)	missense	probably damaging	0.98
IGL02990:Tep1	APN	14	50,868,246 (GRCm38)	missense	possibly damaging	0.86
IGL03144:Tep1	APN	14	50,844,017 (GRCm38)	splice site	probably benign
IGL03209:Tep1	APN	14	50,840,703 (GRCm38)	splice site	probably benign
R0240_Tep1_347	UTSW	14	50,863,029 (GRCm38)	splice site	probably benign
R0972_Tep1_893	UTSW	14	50,824,296 (GRCm38)	unclassified	probably benign
R1686_Tep1_375	UTSW	14	50,836,788 (GRCm38)	missense	probably benign	0.12
R7232_Tep1_671	UTSW	14	50,844,332 (GRCm38)	missense	unknown
R8009_Tep1_822	UTSW	14	50,824,230 (GRCm38)	missense	possibly damaging	0.93
PIT4305001:Tep1	UTSW	14	50,829,227 (GRCm38)	missense	possibly damaging	0.90
PIT4362001:Tep1	UTSW	14	50,866,053 (GRCm38)	missense	probably benign	0.23
R0058:Tep1	UTSW	14	50,834,065 (GRCm38)	missense	possibly damaging	0.85
R0060:Tep1	UTSW	14	50,866,029 (GRCm38)	missense	probably damaging	1.00
R0109:Tep1	UTSW	14	50,851,916 (GRCm38)	splice site	probably null
R0123:Tep1	UTSW	14	50,829,693 (GRCm38)	missense	possibly damaging	0.84
R0134:Tep1	UTSW	14	50,829,693 (GRCm38)	missense	possibly damaging	0.84
R0148:Tep1	UTSW	14	50,824,789 (GRCm38)	missense	possibly damaging	0.70
R0240:Tep1	UTSW	14	50,863,029 (GRCm38)	splice site	probably benign
R0243:Tep1	UTSW	14	50,846,987 (GRCm38)	missense	probably damaging	1.00
R0373:Tep1	UTSW	14	50,836,768 (GRCm38)	missense	possibly damaging	0.85
R0432:Tep1	UTSW	14	50,866,823 (GRCm38)	small deletion	probably benign
R0464:Tep1	UTSW	14	50,847,684 (GRCm38)	missense	probably benign	0.00
R0566:Tep1	UTSW	14	50,845,414 (GRCm38)	critical splice donor site	probably null
R0691:Tep1	UTSW	14	50,866,844 (GRCm38)	nonsense	probably null
R0787:Tep1	UTSW	14	50,829,230 (GRCm38)	missense	possibly damaging	0.85
R0972:Tep1	UTSW	14	50,824,296 (GRCm38)	unclassified	probably benign
R1263:Tep1	UTSW	14	50,845,513 (GRCm38)	missense	possibly damaging	0.84
R1300:Tep1	UTSW	14	50,827,055 (GRCm38)	critical splice donor site	probably null
R1327:Tep1	UTSW	14	50,853,099 (GRCm38)	missense	probably benign	0.18
R1556:Tep1	UTSW	14	50,853,042 (GRCm38)	missense	probably benign	0.06
R1607:Tep1	UTSW	14	50,824,563 (GRCm38)	missense	probably null	0.99
R1686:Tep1	UTSW	14	50,836,788 (GRCm38)	missense	probably benign	0.12
R1715:Tep1	UTSW	14	50,854,567 (GRCm38)	missense	possibly damaging	0.92
R1778:Tep1	UTSW	14	50,829,622 (GRCm38)	intron	probably benign
R1993:Tep1	UTSW	14	50,824,184 (GRCm38)	missense	possibly damaging	0.93
R2071:Tep1	UTSW	14	50,854,282 (GRCm38)	missense	probably benign	0.23
R2104:Tep1	UTSW	14	50,850,580 (GRCm38)	splice site	probably benign
R2118:Tep1	UTSW	14	50,855,572 (GRCm38)	splice site	probably null
R2119:Tep1	UTSW	14	50,838,986 (GRCm38)	missense	probably benign	0.13
R2208:Tep1	UTSW	14	50,866,864 (GRCm38)	missense	probably benign	0.01
R2241:Tep1	UTSW	14	50,854,210 (GRCm38)	missense	probably benign	0.01
R2243:Tep1	UTSW	14	50,854,210 (GRCm38)	missense	probably benign	0.01
R2311:Tep1	UTSW	14	50,833,567 (GRCm38)	missense	possibly damaging	0.95
R2420:Tep1	UTSW	14	50,834,023 (GRCm38)	missense	probably benign
R2874:Tep1	UTSW	14	50,850,650 (GRCm38)	missense	possibly damaging	0.71
R3084:Tep1	UTSW	14	50,827,054 (GRCm38)	critical splice donor site	probably null
R3086:Tep1	UTSW	14	50,827,054 (GRCm38)	critical splice donor site	probably null
R3621:Tep1	UTSW	14	50,829,020 (GRCm38)	missense	probably damaging	0.99
R3815:Tep1	UTSW	14	50,868,315 (GRCm38)	missense	possibly damaging	0.71
R4124:Tep1	UTSW	14	50,843,734 (GRCm38)	missense	possibly damaging	0.93
R4125:Tep1	UTSW	14	50,843,734 (GRCm38)	missense	possibly damaging	0.93
R4127:Tep1	UTSW	14	50,843,734 (GRCm38)	missense	possibly damaging	0.93
R4134:Tep1	UTSW	14	50,844,860 (GRCm38)	missense	probably benign
R4152:Tep1	UTSW	14	50,837,594 (GRCm38)	missense	possibly damaging	0.72
R4153:Tep1	UTSW	14	50,837,594 (GRCm38)	missense	possibly damaging	0.72
R4191:Tep1	UTSW	14	50,836,806 (GRCm38)	missense	probably damaging	0.96
R4248:Tep1	UTSW	14	50,862,894 (GRCm38)	missense	possibly damaging	0.93
R4293:Tep1	UTSW	14	50,846,861 (GRCm38)	missense	probably benign
R4569:Tep1	UTSW	14	50,824,740 (GRCm38)	missense	probably benign	0.01
R4704:Tep1	UTSW	14	50,837,073 (GRCm38)	missense	probably benign	0.06
R4815:Tep1	UTSW	14	50,841,302 (GRCm38)	missense	probably damaging	0.99
R4978:Tep1	UTSW	14	50,845,434 (GRCm38)	missense	possibly damaging	0.93
R4989:Tep1	UTSW	14	50,839,000 (GRCm38)	missense	probably benign
R5022:Tep1	UTSW	14	50,828,999 (GRCm38)	missense	probably benign	0.27
R5057:Tep1	UTSW	14	50,828,999 (GRCm38)	missense	probably benign	0.27
R5063:Tep1	UTSW	14	50,850,627 (GRCm38)	missense	possibly damaging	0.86
R5118:Tep1	UTSW	14	50,855,587 (GRCm38)	splice site	probably null
R5128:Tep1	UTSW	14	50,844,279 (GRCm38)	makesense	probably null
R5149:Tep1	UTSW	14	50,837,398 (GRCm38)	nonsense	probably null
R5171:Tep1	UTSW	14	50,824,802 (GRCm38)	missense	probably benign	0.01
R5201:Tep1	UTSW	14	50,868,110 (GRCm38)	missense	probably benign	0.01
R5260:Tep1	UTSW	14	50,838,631 (GRCm38)	missense	probably benign
R5339:Tep1	UTSW	14	50,844,574 (GRCm38)	missense	probably damaging	0.99
R5384:Tep1	UTSW	14	50,868,317 (GRCm38)	missense	probably damaging	0.98
R5385:Tep1	UTSW	14	50,868,317 (GRCm38)	missense	probably damaging	0.98
R5386:Tep1	UTSW	14	50,868,317 (GRCm38)	missense	probably damaging	0.98
R5594:Tep1	UTSW	14	50,829,882 (GRCm38)	missense	possibly damaging	0.86
R5639:Tep1	UTSW	14	50,853,605 (GRCm38)	missense	possibly damaging	0.85
R5749:Tep1	UTSW	14	50,844,072 (GRCm38)	missense	possibly damaging	0.59
R5756:Tep1	UTSW	14	50,837,379 (GRCm38)	critical splice donor site	probably null
R6013:Tep1	UTSW	14	50,861,048 (GRCm38)	missense	probably damaging	0.97
R6014:Tep1	UTSW	14	50,847,000 (GRCm38)	missense	probably benign	0.12
R6248:Tep1	UTSW	14	50,830,258 (GRCm38)	missense	probably damaging	0.98
R6264:Tep1	UTSW	14	50,845,513 (GRCm38)	missense	probably damaging	0.99
R6363:Tep1	UTSW	14	50,824,548 (GRCm38)	missense	probably benign	0.04
R6381:Tep1	UTSW	14	50,845,431 (GRCm38)	missense	probably damaging	0.99
R6462:Tep1	UTSW	14	50,844,379 (GRCm38)	missense	probably benign
R6942:Tep1	UTSW	14	50,836,737 (GRCm38)	missense	possibly damaging	0.85
R6951:Tep1	UTSW	14	50,833,913 (GRCm38)	critical splice donor site	probably null
R6979:Tep1	UTSW	14	50,838,637 (GRCm38)	missense	possibly damaging	0.93
R6999:Tep1	UTSW	14	50,850,705 (GRCm38)	missense	possibly damaging	0.86
R7099:Tep1	UTSW	14	50,844,487 (GRCm38)	splice site	probably null
R7208:Tep1	UTSW	14	50,824,556 (GRCm38)	critical splice acceptor site	probably null
R7232:Tep1	UTSW	14	50,844,332 (GRCm38)	missense	unknown
R7249:Tep1	UTSW	14	50,824,275 (GRCm38)	missense	possibly damaging	0.86
R7325:Tep1	UTSW	14	50,866,038 (GRCm38)	missense	probably damaging	0.99
R7409:Tep1	UTSW	14	50,866,855 (GRCm38)	missense	possibly damaging	0.67
R7499:Tep1	UTSW	14	50,853,590 (GRCm38)	missense	probably damaging	0.99
R7542:Tep1	UTSW	14	50,862,491 (GRCm38)	nonsense	probably null
R7806:Tep1	UTSW	14	50,836,809 (GRCm38)	missense	possibly damaging	0.85
R7825:Tep1	UTSW	14	50,843,887 (GRCm38)	critical splice acceptor site	probably null
R7901:Tep1	UTSW	14	50,826,851 (GRCm38)	missense	possibly damaging	0.88
R7961:Tep1	UTSW	14	50,824,230 (GRCm38)	missense	possibly damaging	0.93
R7993:Tep1	UTSW	14	50,830,253 (GRCm38)	missense	probably benign	0.41
R8009:Tep1	UTSW	14	50,824,230 (GRCm38)	missense	possibly damaging	0.93
R8085:Tep1	UTSW	14	50,829,296 (GRCm38)	missense	probably benign	0.11
R8299:Tep1	UTSW	14	50,868,045 (GRCm38)	missense	probably benign	0.06
R8330:Tep1	UTSW	14	50,847,705 (GRCm38)	missense	possibly damaging	0.86
R8396:Tep1	UTSW	14	50,837,072 (GRCm38)	missense	probably benign	0.23
R8475:Tep1	UTSW	14	50,841,255 (GRCm38)	missense	probably damaging	1.00
R8695:Tep1	UTSW	14	50,845,437 (GRCm38)	missense	possibly damaging	0.85
R8726:Tep1	UTSW	14	50,847,623 (GRCm38)	missense	probably damaging	0.98
R8812:Tep1	UTSW	14	50,837,132 (GRCm38)	missense	probably damaging	0.98
R9152:Tep1	UTSW	14	50,866,705 (GRCm38)	missense	probably benign	0.14
R9269:Tep1	UTSW	14	50,844,309 (GRCm38)	missense	probably damaging	0.98
R9299:Tep1	UTSW	14	50,844,531 (GRCm38)	splice site	probably benign
R9365:Tep1	UTSW	14	50,827,140 (GRCm38)	missense	probably damaging	1.00
R9398:Tep1	UTSW	14	50,828,972 (GRCm38)	missense	possibly damaging	0.85
R9408:Tep1	UTSW	14	50,837,180 (GRCm38)	missense	possibly damaging	0.85
R9445:Tep1	UTSW	14	50,845,510 (GRCm38)	missense	possibly damaging	0.95
R9487:Tep1	UTSW	14	50,829,230 (GRCm38)	missense	possibly damaging	0.93
R9555:Tep1	UTSW	14	50,868,431 (GRCm38)	missense	possibly damaging	0.52
R9597:Tep1	UTSW	14	50,863,008 (GRCm38)	missense	probably damaging	0.99
R9715:Tep1	UTSW	14	50,844,302 (GRCm38)	missense
R9732:Tep1	UTSW	14	50,850,705 (GRCm38)	missense	probably benign	0.33
R9777:Tep1	UTSW	14	50,838,986 (GRCm38)	nonsense	probably null
RF007:Tep1	UTSW	14	50,860,945 (GRCm38)	missense	possibly damaging	0.92
X0024:Tep1	UTSW	14	50,827,119 (GRCm38)	missense	possibly damaging	0.86
X0060:Tep1	UTSW	14	50,836,764 (GRCm38)	missense	probably benign	0.25
Z1177:Tep1	UTSW	14	50,847,765 (GRCm38)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- GAGCCAATAACCAGCTCTTCGTACC -3'
(R):5'- AGGGAAAAGATCCCGTTTCCTGC -3'

Sequencing Primer
(F):5'- TAACCAGCTCTTCGTACCATAATTAC -3'
(R):5'- tgggaggcagaggcagg -3'

Posted On

2014-04-24