Incidental Mutation 'R1585:Nlrp9a'
| ID |
177433 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
039622-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
R1585 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 26258093 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 570
(D570E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113318
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000071780
AA Change: D570E
PolyPhen 2
Score 0.415 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: D570E
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108387
AA Change: D570E
PolyPhen 2
Score 0.415 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: D570E
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117252
AA Change: D570E
PolyPhen 2
Score 0.134 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: D570E
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122040
AA Change: D570E
PolyPhen 2
Score 0.415 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: D570E
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153452
AA Change: D481E
PolyPhen 2
Score 0.134 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
AA Change: D481E
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.1%
- 10x: 95.7%
- 20x: 91.2%
|
| Validation Efficiency |
95% (81/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310057J18Rik |
T |
A |
10: 28,858,518 (GRCm39) |
I50F |
possibly damaging |
Het |
| 4930505A04Rik |
T |
C |
11: 30,377,175 (GRCm39) |
|
probably benign |
Het |
| Aadat |
A |
T |
8: 60,979,714 (GRCm39) |
D192V |
possibly damaging |
Het |
| Akap12 |
A |
G |
10: 4,303,640 (GRCm39) |
D150G |
probably benign |
Het |
| Amigo3 |
A |
T |
9: 107,931,231 (GRCm39) |
N218I |
probably damaging |
Het |
| Ankmy1 |
A |
G |
1: 92,827,373 (GRCm39) |
S60P |
probably benign |
Het |
| Apol7e |
G |
A |
15: 77,602,029 (GRCm39) |
S209N |
probably damaging |
Het |
| AW551984 |
A |
T |
9: 39,510,632 (GRCm39) |
Y234* |
probably null |
Het |
| Bcam |
A |
T |
7: 19,494,111 (GRCm39) |
D393E |
probably damaging |
Het |
| Card9 |
A |
G |
2: 26,244,398 (GRCm39) |
L444P |
probably benign |
Het |
| Ccar1 |
T |
C |
10: 62,586,780 (GRCm39) |
E886G |
unknown |
Het |
| Ccnb2 |
A |
T |
9: 70,317,559 (GRCm39) |
|
probably null |
Het |
| Cd276 |
T |
C |
9: 58,442,838 (GRCm39) |
S206G |
probably damaging |
Het |
| Cds1 |
T |
A |
5: 101,965,828 (GRCm39) |
|
probably benign |
Het |
| Cfap96 |
G |
A |
8: 46,409,515 (GRCm39) |
S268L |
probably benign |
Het |
| Chuk |
T |
C |
19: 44,065,812 (GRCm39) |
S661G |
possibly damaging |
Het |
| Col17a1 |
T |
C |
19: 47,639,276 (GRCm39) |
N1090D |
probably benign |
Het |
| Col3a1 |
A |
T |
1: 45,367,026 (GRCm39) |
|
probably null |
Het |
| Crispld1 |
G |
T |
1: 17,821,024 (GRCm39) |
V355F |
possibly damaging |
Het |
| Cspg4 |
A |
T |
9: 56,806,151 (GRCm39) |
R2321W |
probably damaging |
Het |
| Dner |
T |
C |
1: 84,563,177 (GRCm39) |
T61A |
probably benign |
Het |
| Dnmt3a |
A |
T |
12: 3,951,660 (GRCm39) |
Y679F |
probably damaging |
Het |
| Dzip3 |
A |
T |
16: 48,798,241 (GRCm39) |
|
probably benign |
Het |
| Eif3l |
T |
C |
15: 78,968,381 (GRCm39) |
S217P |
possibly damaging |
Het |
| Fbxo42 |
T |
A |
4: 140,925,417 (GRCm39) |
|
probably benign |
Het |
| Fhod1 |
A |
T |
8: 106,063,957 (GRCm39) |
|
probably benign |
Het |
| Fzd1 |
T |
A |
5: 4,806,278 (GRCm39) |
I435F |
probably damaging |
Het |
| Gapvd1 |
C |
T |
2: 34,602,207 (GRCm39) |
V647I |
possibly damaging |
Het |
| Gm14496 |
T |
C |
2: 181,638,002 (GRCm39) |
S359P |
possibly damaging |
Het |
| Gm5218 |
C |
A |
15: 81,383,741 (GRCm39) |
|
noncoding transcript |
Het |
| Hnrnph3 |
A |
G |
10: 62,851,579 (GRCm39) |
|
probably null |
Het |
| Hsd17b12 |
G |
T |
2: 93,864,321 (GRCm39) |
T262K |
probably damaging |
Het |
| Igsf10 |
G |
C |
3: 59,237,838 (GRCm39) |
P781R |
probably damaging |
Het |
| Il11ra1 |
T |
A |
4: 41,768,207 (GRCm39) |
S373T |
probably damaging |
Het |
| Kdm3b |
A |
G |
18: 34,942,345 (GRCm39) |
D612G |
probably damaging |
Het |
| Ldb1 |
T |
C |
19: 46,022,903 (GRCm39) |
T261A |
probably damaging |
Het |
| Lep |
C |
A |
6: 29,069,089 (GRCm39) |
H47N |
possibly damaging |
Het |
| Lrrtm2 |
A |
T |
18: 35,346,428 (GRCm39) |
S291R |
possibly damaging |
Het |
| Ncor2 |
T |
C |
5: 125,162,062 (GRCm39) |
Q404R |
unknown |
Het |
| Nlrp4d |
T |
C |
7: 10,116,437 (GRCm39) |
H148R |
probably benign |
Het |
| Nphp3 |
G |
A |
9: 103,886,413 (GRCm39) |
V202I |
probably damaging |
Het |
| Nptn |
T |
A |
9: 58,548,073 (GRCm39) |
N159K |
probably benign |
Het |
| Or4a69 |
T |
A |
2: 89,313,315 (GRCm39) |
T55S |
probably benign |
Het |
| Or4a72 |
A |
T |
2: 89,405,746 (GRCm39) |
V108D |
possibly damaging |
Het |
| Or51f2 |
G |
A |
7: 102,526,980 (GRCm39) |
V218I |
probably benign |
Het |
| Or52a24 |
A |
T |
7: 103,381,585 (GRCm39) |
T151S |
possibly damaging |
Het |
| Or8b53 |
A |
T |
9: 38,667,716 (GRCm39) |
H244L |
probably damaging |
Het |
| Pcolce |
T |
A |
5: 137,608,769 (GRCm39) |
R13* |
probably null |
Het |
| Pdgfra |
A |
G |
5: 75,353,264 (GRCm39) |
Y1018C |
probably damaging |
Het |
| Prima1 |
A |
G |
12: 103,201,854 (GRCm39) |
S74P |
probably damaging |
Het |
| Prl7c1 |
A |
G |
13: 27,962,838 (GRCm39) |
L55P |
probably damaging |
Het |
| Rasef |
A |
G |
4: 73,658,574 (GRCm39) |
V513A |
probably damaging |
Het |
| Rgs1 |
T |
C |
1: 144,121,227 (GRCm39) |
|
probably null |
Het |
| Rlf |
T |
C |
4: 121,005,488 (GRCm39) |
E1164G |
probably benign |
Het |
| Rnf213 |
A |
T |
11: 119,354,171 (GRCm39) |
N4016I |
probably damaging |
Het |
| Sae1 |
C |
T |
7: 16,064,537 (GRCm39) |
|
probably null |
Het |
| Serping1 |
A |
T |
2: 84,601,848 (GRCm39) |
D207E |
probably benign |
Het |
| Setd2 |
T |
A |
9: 110,380,464 (GRCm39) |
D33E |
unknown |
Het |
| Simc1 |
T |
C |
13: 54,673,071 (GRCm39) |
M473T |
probably benign |
Het |
| Slc30a6 |
T |
A |
17: 74,725,610 (GRCm39) |
|
probably benign |
Het |
| Slc4a5 |
T |
C |
6: 83,242,669 (GRCm39) |
L346P |
probably damaging |
Het |
| Spef2 |
T |
A |
15: 9,596,660 (GRCm39) |
Q1473L |
probably damaging |
Het |
| St3gal3 |
G |
T |
4: 117,817,204 (GRCm39) |
A44D |
possibly damaging |
Het |
| Sv2b |
G |
T |
7: 74,797,425 (GRCm39) |
T323K |
probably damaging |
Het |
| Sycp2 |
T |
A |
2: 177,993,461 (GRCm39) |
N1228I |
possibly damaging |
Het |
| Thbs2 |
T |
A |
17: 14,910,030 (GRCm39) |
M190L |
probably benign |
Het |
| Tnrc6a |
G |
A |
7: 122,776,098 (GRCm39) |
V1190I |
probably benign |
Het |
| Utrn |
A |
T |
10: 12,312,029 (GRCm39) |
I673K |
possibly damaging |
Het |
| Vmn2r114 |
C |
T |
17: 23,510,675 (GRCm39) |
V602M |
probably damaging |
Het |
| Wdr7 |
A |
T |
18: 64,057,989 (GRCm39) |
I1273L |
probably benign |
Het |
| Zfp618 |
T |
C |
4: 63,051,175 (GRCm39) |
L652P |
probably damaging |
Het |
| Zfp804a |
G |
A |
2: 81,884,095 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3110:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Nlrp9a
|
UTSW |
7 |
26,256,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Nlrp9a
|
UTSW |
7 |
26,250,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Nlrp9a
|
UTSW |
7 |
26,256,811 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9271:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTCCTTGCTTGAACCATGCTTTGG -3'
(R):5'- CAGCAGTATGAAGTCTCAATAGGAAGCC -3'
Sequencing Primer
(F):5'- TGGCTGTATATCATCCAAGGAG -3'
(R):5'- tggagagagggtagaatggg -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation