Incidental Mutation 'R1589:Wdr17'
| ID |
177730 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr17
|
| Ensembl Gene |
ENSMUSG00000039375 |
| Gene Name |
WD repeat domain 17 |
| Synonyms |
B230207L18Rik, 3010002I12Rik |
| MMRRC Submission |
039626-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1589 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
55082316-55180014 bp(-) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
C to T
at 55156942 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134978
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000127511]
[ENSMUST00000129132]
[ENSMUST00000144711]
[ENSMUST00000148408]
[ENSMUST00000150488]
[ENSMUST00000176866]
[ENSMUST00000175915]
|
| AlphaFold |
E9Q271 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126316
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000127511
|
| SMART Domains |
Protein: ENSMUSP00000115550
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
72 |
112 |
8.55e-8 |
SMART |
|
WD40
|
162 |
202 |
1.58e2 |
SMART |
|
WD40
|
205 |
252 |
4.26e1 |
SMART |
|
WD40
|
255 |
298 |
1.15e0 |
SMART |
|
WD40
|
383 |
422 |
1.59e-7 |
SMART |
|
WD40
|
425 |
465 |
2.39e0 |
SMART |
|
WD40
|
468 |
509 |
5.52e-2 |
SMART |
|
WD40
|
511 |
550 |
4.14e-6 |
SMART |
|
WD40
|
555 |
595 |
5.14e-11 |
SMART |
|
WD40
|
598 |
638 |
6.58e-9 |
SMART |
|
WD40
|
641 |
681 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129132
|
| SMART Domains |
Protein: ENSMUSP00000134935
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
Blast:WD40
|
91 |
131 |
1e-12 |
BLAST |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
271 |
9.86e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144711
|
| SMART Domains |
Protein: ENSMUSP00000117710
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
72 |
112 |
8.55e-8 |
SMART |
|
WD40
|
194 |
235 |
7.64e1 |
SMART |
|
WD40
|
238 |
281 |
1.15e0 |
SMART |
|
WD40
|
366 |
405 |
1.59e-7 |
SMART |
|
WD40
|
408 |
448 |
2.39e0 |
SMART |
|
WD40
|
451 |
492 |
5.52e-2 |
SMART |
|
WD40
|
494 |
533 |
4.14e-6 |
SMART |
|
WD40
|
538 |
578 |
5.14e-11 |
SMART |
|
WD40
|
581 |
621 |
6.58e-9 |
SMART |
|
WD40
|
624 |
664 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148408
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148806
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150488
|
| SMART Domains |
Protein: ENSMUSP00000122326
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
274 |
1.15e0 |
SMART |
|
WD40
|
359 |
398 |
1.59e-7 |
SMART |
|
WD40
|
401 |
441 |
2.39e0 |
SMART |
|
WD40
|
444 |
485 |
5.52e-2 |
SMART |
|
WD40
|
487 |
526 |
4.14e-6 |
SMART |
|
WD40
|
531 |
571 |
5.14e-11 |
SMART |
|
WD40
|
574 |
614 |
6.58e-9 |
SMART |
|
WD40
|
617 |
657 |
6.28e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176866
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175915
|
| SMART Domains |
Protein: ENSMUSP00000135805
Gene: ENSMUSG00000039375
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
48 |
88 |
8.55e-8 |
SMART |
|
WD40
|
138 |
178 |
1.58e2 |
SMART |
|
WD40
|
181 |
228 |
4.26e1 |
SMART |
|
WD40
|
231 |
274 |
1.15e0 |
SMART |
|
WD40
|
359 |
398 |
1.59e-7 |
SMART |
|
WD40
|
401 |
441 |
2.39e0 |
SMART |
|
WD40
|
444 |
485 |
5.52e-2 |
SMART |
|
WD40
|
487 |
526 |
4.14e-6 |
SMART |
|
WD40
|
531 |
571 |
5.14e-11 |
SMART |
|
WD40
|
574 |
614 |
6.58e-9 |
SMART |
|
WD40
|
617 |
657 |
6.28e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.8%
- 20x: 90.8%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a WD repeat-containing protein. It is abundantly expressed in retina and testis, and is thought to be a candidate gene for retinal disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700008P02Rik |
A |
G |
3: 6,685,501 (GRCm39) |
|
probably benign |
Het |
| Aadacl2 |
C |
T |
3: 59,917,997 (GRCm39) |
T82I |
probably benign |
Het |
| Acadl |
T |
C |
1: 66,892,382 (GRCm39) |
N147S |
probably benign |
Het |
| Actr3 |
A |
T |
1: 125,336,300 (GRCm39) |
M79K |
probably damaging |
Het |
| Agbl3 |
A |
G |
6: 34,834,452 (GRCm39) |
S874G |
possibly damaging |
Het |
| Aoah |
A |
T |
13: 21,187,118 (GRCm39) |
T472S |
probably damaging |
Het |
| Asb16 |
A |
T |
11: 102,159,821 (GRCm39) |
D58V |
probably damaging |
Het |
| B4galt1 |
T |
C |
4: 40,823,575 (GRCm39) |
D172G |
probably benign |
Het |
| Bax |
T |
C |
7: 45,114,671 (GRCm39) |
N55S |
possibly damaging |
Het |
| Bdkrb2 |
A |
G |
12: 105,558,118 (GRCm39) |
N120D |
possibly damaging |
Het |
| Bicdl1 |
T |
C |
5: 115,789,325 (GRCm39) |
|
probably benign |
Het |
| Cand1 |
A |
G |
10: 119,049,471 (GRCm39) |
L425P |
probably damaging |
Het |
| Caskin1 |
G |
A |
17: 24,724,452 (GRCm39) |
|
probably null |
Het |
| Cd248 |
C |
T |
19: 5,119,960 (GRCm39) |
P603S |
probably benign |
Het |
| Cep95 |
G |
T |
11: 106,690,930 (GRCm39) |
R143L |
probably benign |
Het |
| Clptm1l |
G |
T |
13: 73,762,792 (GRCm39) |
|
probably null |
Het |
| Cntnap5a |
T |
C |
1: 115,987,930 (GRCm39) |
F154L |
possibly damaging |
Het |
| Cyld |
A |
T |
8: 89,436,618 (GRCm39) |
I303F |
possibly damaging |
Het |
| Dock2 |
A |
G |
11: 34,597,288 (GRCm39) |
S370P |
probably damaging |
Het |
| Enah |
G |
T |
1: 181,749,858 (GRCm39) |
T327K |
probably damaging |
Het |
| Farp2 |
A |
T |
1: 93,507,582 (GRCm39) |
S427C |
probably damaging |
Het |
| Fbxw11 |
C |
T |
11: 32,683,612 (GRCm39) |
T301M |
probably damaging |
Het |
| Foxc2 |
A |
T |
8: 121,843,915 (GRCm39) |
T188S |
probably benign |
Het |
| Fzd2 |
A |
G |
11: 102,497,154 (GRCm39) |
T533A |
probably benign |
Het |
| Glb1l2 |
G |
T |
9: 26,680,334 (GRCm39) |
S248* |
probably null |
Het |
| Glul |
A |
T |
1: 153,781,284 (GRCm39) |
|
probably benign |
Het |
| Gm28042 |
A |
G |
2: 119,871,887 (GRCm39) |
T946A |
probably benign |
Het |
| Golga3 |
T |
A |
5: 110,329,649 (GRCm39) |
D2E |
probably damaging |
Het |
| Grm1 |
A |
T |
10: 10,595,711 (GRCm39) |
F639Y |
probably benign |
Het |
| Gzmn |
A |
G |
14: 56,403,368 (GRCm39) |
L247P |
probably benign |
Het |
| Hgf |
T |
G |
5: 16,818,783 (GRCm39) |
I525R |
probably damaging |
Het |
| Hnrnpul2 |
T |
A |
19: 8,808,696 (GRCm39) |
D719E |
probably benign |
Het |
| Itga10 |
C |
T |
3: 96,559,054 (GRCm39) |
|
probably benign |
Het |
| Itga9 |
T |
C |
9: 118,436,185 (GRCm39) |
|
probably null |
Het |
| Itgb1 |
T |
A |
8: 129,431,939 (GRCm39) |
C16S |
probably damaging |
Het |
| Itgb1 |
G |
T |
8: 129,431,940 (GRCm39) |
C16F |
possibly damaging |
Het |
| Kat14 |
A |
G |
2: 144,236,020 (GRCm39) |
I251V |
probably benign |
Het |
| Kdsr |
A |
T |
1: 106,662,271 (GRCm39) |
|
probably null |
Het |
| Kif12 |
T |
A |
4: 63,084,737 (GRCm39) |
E527V |
probably benign |
Het |
| Larp1b |
T |
C |
3: 40,987,909 (GRCm39) |
S44P |
probably damaging |
Het |
| Lonp2 |
T |
C |
8: 87,399,700 (GRCm39) |
|
probably benign |
Het |
| Lrp1 |
C |
T |
10: 127,441,475 (GRCm39) |
S216N |
probably benign |
Het |
| Lrrc19 |
T |
C |
4: 94,529,187 (GRCm39) |
S32G |
probably benign |
Het |
| Mdm2 |
G |
A |
10: 117,526,434 (GRCm39) |
T335M |
probably benign |
Het |
| Mettl25 |
A |
G |
10: 105,615,493 (GRCm39) |
Y504H |
probably damaging |
Het |
| Mill1 |
T |
C |
7: 17,979,572 (GRCm39) |
I13T |
probably benign |
Het |
| Mmachc |
T |
A |
4: 116,560,721 (GRCm39) |
Q258L |
probably benign |
Het |
| Mpdz |
T |
A |
4: 81,339,413 (GRCm39) |
I5L |
probably benign |
Het |
| Mrps2 |
C |
T |
2: 28,359,500 (GRCm39) |
A119V |
probably benign |
Het |
| Mtcl2 |
A |
T |
2: 156,869,557 (GRCm39) |
M1026K |
probably benign |
Het |
| Mtmr11 |
A |
G |
3: 96,075,429 (GRCm39) |
T370A |
probably benign |
Het |
| Nmi |
T |
C |
2: 51,848,989 (GRCm39) |
I34V |
possibly damaging |
Het |
| Obscn |
A |
T |
11: 58,926,901 (GRCm39) |
M5538K |
possibly damaging |
Het |
| Ogdhl |
T |
C |
14: 32,047,822 (GRCm39) |
I24T |
probably benign |
Het |
| Omp |
G |
T |
7: 97,794,566 (GRCm39) |
D20E |
probably benign |
Het |
| Or2ag19 |
A |
G |
7: 106,444,403 (GRCm39) |
Y195C |
possibly damaging |
Het |
| Or52e8b |
A |
G |
7: 104,673,767 (GRCm39) |
V140A |
probably benign |
Het |
| Or5b120 |
C |
T |
19: 13,480,121 (GRCm39) |
T138M |
probably benign |
Het |
| Or6c69 |
A |
G |
10: 129,747,550 (GRCm39) |
V199A |
probably benign |
Het |
| Otog |
A |
G |
7: 45,933,332 (GRCm39) |
H1291R |
probably benign |
Het |
| Pgbd1 |
A |
G |
13: 21,607,462 (GRCm39) |
L244P |
probably damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,299,808 (GRCm39) |
I481V |
probably benign |
Het |
| Rbp3 |
A |
T |
14: 33,677,749 (GRCm39) |
I566F |
probably damaging |
Het |
| Rsph4a |
A |
G |
10: 33,781,525 (GRCm39) |
D125G |
probably benign |
Het |
| Scn11a |
A |
G |
9: 119,598,873 (GRCm39) |
V1219A |
probably damaging |
Het |
| Serpine3 |
G |
A |
14: 62,911,830 (GRCm39) |
G264D |
probably benign |
Het |
| Slc4a10 |
T |
C |
2: 62,087,806 (GRCm39) |
F400L |
probably damaging |
Het |
| Slco1a4 |
C |
T |
6: 141,791,173 (GRCm39) |
V8I |
probably benign |
Het |
| Spen |
T |
C |
4: 141,215,335 (GRCm39) |
D499G |
unknown |
Het |
| Stk32c |
A |
G |
7: 138,698,931 (GRCm39) |
|
probably null |
Het |
| Tars1 |
A |
G |
15: 11,388,261 (GRCm39) |
V485A |
probably benign |
Het |
| Tcerg1l |
A |
G |
7: 137,963,496 (GRCm39) |
L258P |
probably damaging |
Het |
| Tmc2 |
A |
T |
2: 130,089,880 (GRCm39) |
I622F |
probably damaging |
Het |
| Tmem183a |
A |
T |
1: 134,282,444 (GRCm39) |
N220K |
probably damaging |
Het |
| Tnni3 |
T |
C |
7: 4,523,525 (GRCm39) |
D146G |
probably damaging |
Het |
| Trappc11 |
G |
T |
8: 47,954,715 (GRCm39) |
D908E |
probably damaging |
Het |
| Trappc8 |
A |
G |
18: 20,996,608 (GRCm39) |
Y436H |
probably damaging |
Het |
| Ttc41 |
G |
A |
10: 86,612,254 (GRCm39) |
V1176I |
probably benign |
Het |
| Ube2b |
A |
G |
11: 51,888,699 (GRCm39) |
V24A |
probably benign |
Het |
| Usp30 |
T |
C |
5: 114,251,022 (GRCm39) |
C233R |
probably damaging |
Het |
| Vmn1r87 |
T |
A |
7: 12,865,703 (GRCm39) |
T195S |
possibly damaging |
Het |
| Vmn2r24 |
T |
C |
6: 123,783,479 (GRCm39) |
|
probably benign |
Het |
| Vmn2r81 |
C |
A |
10: 79,128,858 (GRCm39) |
T583N |
probably damaging |
Het |
| Vwa8 |
C |
T |
14: 79,145,670 (GRCm39) |
R116C |
probably damaging |
Het |
| Wdr1 |
C |
A |
5: 38,687,315 (GRCm39) |
V239L |
probably benign |
Het |
| Zfhx4 |
A |
C |
3: 5,306,789 (GRCm39) |
D5A |
probably damaging |
Het |
| Zfyve27 |
T |
C |
19: 42,160,184 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Wdr17 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00309:Wdr17
|
APN |
8 |
55,140,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00496:Wdr17
|
APN |
8 |
55,112,614 (GRCm39) |
splice site |
probably benign |
|
|
IGL01318:Wdr17
|
APN |
8 |
55,125,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01347:Wdr17
|
APN |
8 |
55,104,380 (GRCm39) |
missense |
probably benign |
|
|
IGL01654:Wdr17
|
APN |
8 |
55,115,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02010:Wdr17
|
APN |
8 |
55,112,738 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02085:Wdr17
|
APN |
8 |
55,140,771 (GRCm39) |
nonsense |
probably null |
|
|
IGL02205:Wdr17
|
APN |
8 |
55,149,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02375:Wdr17
|
APN |
8 |
55,149,423 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02705:Wdr17
|
APN |
8 |
55,101,250 (GRCm39) |
splice site |
probably null |
|
|
IGL02719:Wdr17
|
APN |
8 |
55,146,089 (GRCm39) |
splice site |
probably null |
|
|
IGL03051:Wdr17
|
APN |
8 |
55,104,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03131:Wdr17
|
APN |
8 |
55,149,302 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03172:Wdr17
|
APN |
8 |
55,114,515 (GRCm39) |
missense |
probably damaging |
0.96 |
|
enthralled
|
UTSW |
8 |
55,112,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
riveted
|
UTSW |
8 |
55,085,522 (GRCm39) |
missense |
probably benign |
0.00 |
|
thrilled
|
UTSW |
8 |
55,149,303 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03138:Wdr17
|
UTSW |
8 |
55,102,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4458001:Wdr17
|
UTSW |
8 |
55,126,614 (GRCm39) |
nonsense |
probably null |
|
|
R0011:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0011:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0124:Wdr17
|
UTSW |
8 |
55,088,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0226:Wdr17
|
UTSW |
8 |
55,116,043 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0270:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0271:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0288:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0321:Wdr17
|
UTSW |
8 |
55,149,303 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0464:Wdr17
|
UTSW |
8 |
55,123,427 (GRCm39) |
splice site |
probably benign |
|
|
R0479:Wdr17
|
UTSW |
8 |
55,104,456 (GRCm39) |
splice site |
probably null |
|
|
R0488:Wdr17
|
UTSW |
8 |
55,146,087 (GRCm39) |
unclassified |
probably benign |
|
|
R0552:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0553:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0600:Wdr17
|
UTSW |
8 |
55,114,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0621:Wdr17
|
UTSW |
8 |
55,096,226 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0655:Wdr17
|
UTSW |
8 |
55,102,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0789:Wdr17
|
UTSW |
8 |
55,112,607 (GRCm39) |
splice site |
probably benign |
|
|
R0854:Wdr17
|
UTSW |
8 |
55,156,916 (GRCm39) |
missense |
probably benign |
|
|
R0879:Wdr17
|
UTSW |
8 |
55,114,516 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1462:Wdr17
|
UTSW |
8 |
55,123,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1462:Wdr17
|
UTSW |
8 |
55,123,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1497:Wdr17
|
UTSW |
8 |
55,125,536 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1618:Wdr17
|
UTSW |
8 |
55,092,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Wdr17
|
UTSW |
8 |
55,126,689 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1778:Wdr17
|
UTSW |
8 |
55,143,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1819:Wdr17
|
UTSW |
8 |
55,143,159 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1913:Wdr17
|
UTSW |
8 |
55,140,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Wdr17
|
UTSW |
8 |
55,085,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Wdr17
|
UTSW |
8 |
55,125,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2309:Wdr17
|
UTSW |
8 |
55,096,283 (GRCm39) |
missense |
probably benign |
|
|
R3882:Wdr17
|
UTSW |
8 |
55,092,536 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4097:Wdr17
|
UTSW |
8 |
55,088,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4372:Wdr17
|
UTSW |
8 |
55,092,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4380:Wdr17
|
UTSW |
8 |
55,101,442 (GRCm39) |
intron |
probably benign |
|
|
R4480:Wdr17
|
UTSW |
8 |
55,117,999 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4654:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4656:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4669:Wdr17
|
UTSW |
8 |
55,143,083 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4719:Wdr17
|
UTSW |
8 |
55,092,911 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4912:Wdr17
|
UTSW |
8 |
55,082,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5000:Wdr17
|
UTSW |
8 |
55,118,161 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5073:Wdr17
|
UTSW |
8 |
55,143,271 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5176:Wdr17
|
UTSW |
8 |
55,106,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5194:Wdr17
|
UTSW |
8 |
55,140,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5270:Wdr17
|
UTSW |
8 |
55,096,221 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5300:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5325:Wdr17
|
UTSW |
8 |
55,112,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5336:Wdr17
|
UTSW |
8 |
55,085,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5394:Wdr17
|
UTSW |
8 |
55,092,524 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5424:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5425:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5426:Wdr17
|
UTSW |
8 |
55,134,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5548:Wdr17
|
UTSW |
8 |
55,156,886 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5681:Wdr17
|
UTSW |
8 |
55,115,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5722:Wdr17
|
UTSW |
8 |
55,113,806 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5894:Wdr17
|
UTSW |
8 |
55,149,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5906:Wdr17
|
UTSW |
8 |
55,092,503 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6038:Wdr17
|
UTSW |
8 |
55,085,346 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6038:Wdr17
|
UTSW |
8 |
55,085,346 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6391:Wdr17
|
UTSW |
8 |
55,114,495 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6605:Wdr17
|
UTSW |
8 |
55,134,559 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6892:Wdr17
|
UTSW |
8 |
55,126,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7019:Wdr17
|
UTSW |
8 |
55,134,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7257:Wdr17
|
UTSW |
8 |
55,085,522 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7481:Wdr17
|
UTSW |
8 |
55,114,371 (GRCm39) |
missense |
probably benign |
|
|
R7868:Wdr17
|
UTSW |
8 |
55,149,302 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7939:Wdr17
|
UTSW |
8 |
55,140,677 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7962:Wdr17
|
UTSW |
8 |
55,113,806 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8017:Wdr17
|
UTSW |
8 |
55,091,403 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8122:Wdr17
|
UTSW |
8 |
55,118,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8226:Wdr17
|
UTSW |
8 |
55,146,155 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8251:Wdr17
|
UTSW |
8 |
55,110,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Wdr17
|
UTSW |
8 |
55,115,953 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8534:Wdr17
|
UTSW |
8 |
55,101,265 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8708:Wdr17
|
UTSW |
8 |
55,093,127 (GRCm39) |
intron |
probably benign |
|
|
R9116:Wdr17
|
UTSW |
8 |
55,114,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9258:Wdr17
|
UTSW |
8 |
55,112,654 (GRCm39) |
nonsense |
probably null |
|
|
R9351:Wdr17
|
UTSW |
8 |
55,143,057 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9475:Wdr17
|
UTSW |
8 |
55,088,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9546:Wdr17
|
UTSW |
8 |
55,112,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Wdr17
|
UTSW |
8 |
55,112,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9635:Wdr17
|
UTSW |
8 |
55,101,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
V5088:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
V5622:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
V5622:Wdr17
|
UTSW |
8 |
55,146,131 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
X0022:Wdr17
|
UTSW |
8 |
55,092,529 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0066:Wdr17
|
UTSW |
8 |
55,126,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Wdr17
|
UTSW |
8 |
55,123,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Wdr17
|
UTSW |
8 |
55,096,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGGTAGAACTCATCTAGCGTGCAG -3'
(R):5'- TGGGCAACACAAAATGAACTCCCTG -3'
Sequencing Primer
(F):5'- TAGGGTTCACTCACAACTGAAAAAG -3'
(R):5'- tgtttttgtttgtttgtttggtttg -3'
|
| Posted On |
2014-04-24 |
Incidental Mutation