Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01843:Vmn2r79'

178073

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r79

Ensembl Gene

ENSMUSG00000090362

Gene Name

vomeronasal 2, receptor 79

Synonyms

EG621430

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.093) question?

Stock #

IGL01843

Quality Score

Status

Chromosome

Chromosomal Location

86645673-86687176 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 86686485 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Glutamine at position 622 (L622Q)

Ref Sequence

ENSEMBL: ENSMUSP00000132478 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000164462]

AlphaFold

E9Q067

Predicted Effect

probably damaging
Transcript: ENSMUST00000164462
AA Change: L622Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000132478
Gene: ENSMUSG00000090362
AA Change: L622Q

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	75	464	1.9e-31	PFAM
Pfam:NCD3G	506	559	3.1e-21	PFAM
Pfam:7tm_3	592	827	2.8e-53	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	C	T	6: 128,530,301 (GRCm39)		probably benign	Het
Ap1b1	T	C	11: 4,989,169 (GRCm39)	L782P	probably damaging	Het
Arid1a	T	C	4: 133,408,765 (GRCm39)	D1914G	unknown	Het
C8a	G	A	4: 104,719,808 (GRCm39)	Q57*	probably null	Het
Cachd1	T	C	4: 100,850,069 (GRCm39)	S1144P	probably damaging	Het
Cdh23	A	T	10: 60,255,598 (GRCm39)		probably null	Het
Cenpe	A	G	3: 134,924,268 (GRCm39)	Q198R	possibly damaging	Het
Cpne8	T	C	15: 90,453,700 (GRCm39)	I228V	probably benign	Het
Cr2	A	T	1: 194,833,222 (GRCm39)		probably benign	Het
Csmd3	T	C	15: 47,522,395 (GRCm39)		probably benign	Het
Cyp2c23	A	G	19: 43,994,046 (GRCm39)	V440A	probably benign	Het
Dag1	T	C	9: 108,085,281 (GRCm39)	D620G	possibly damaging	Het
Dmxl1	T	A	18: 50,011,449 (GRCm39)	L1202*	probably null	Het
Dnah3	T	G	7: 119,542,798 (GRCm39)	H3538P	probably benign	Het
Dock8	A	T	19: 25,067,292 (GRCm39)	Q312L	probably benign	Het
E2f7	T	G	10: 110,610,596 (GRCm39)	V407G	probably benign	Het
F13b	T	C	1: 139,444,165 (GRCm39)	S500P	probably damaging	Het
F5	A	G	1: 164,039,395 (GRCm39)	I2002V	probably benign	Het
Flywch1	T	A	17: 23,979,319 (GRCm39)	M439L	possibly damaging	Het
Gcn1	C	A	5: 115,757,759 (GRCm39)	A2488E	probably damaging	Het
Gria1	T	C	11: 57,208,600 (GRCm39)	S832P	probably damaging	Het
Hnrnpr	T	C	4: 136,066,724 (GRCm39)		probably benign	Het
Hps3	A	G	3: 20,083,165 (GRCm39)	I177T	probably benign	Het
Irgm2	G	A	11: 58,111,167 (GRCm39)	G298D	probably benign	Het
Kcnk7	G	A	19: 5,756,230 (GRCm39)	G152D	probably damaging	Het
Man2a2	T	C	7: 80,012,654 (GRCm39)	T620A	probably benign	Het
Mapk12	A	G	15: 89,021,669 (GRCm39)		probably benign	Het
Mapk6	T	C	9: 75,297,572 (GRCm39)	Y315C	probably damaging	Het
Mdga2	T	A	12: 66,769,905 (GRCm39)		probably null	Het
Met	T	A	6: 17,491,700 (GRCm39)	I154N	probably damaging	Het
Mtrex	T	C	13: 113,055,095 (GRCm39)		probably benign	Het
Nap1l1	A	G	10: 111,328,772 (GRCm39)	R234G	possibly damaging	Het
Olfm5	C	A	7: 103,809,951 (GRCm39)	V137F	possibly damaging	Het
Or4d11	G	T	19: 12,014,041 (GRCm39)	H22N	probably benign	Het
Pcdha11	C	T	18: 37,145,886 (GRCm39)	T659I	probably benign	Het
Pfkm	T	C	15: 98,027,187 (GRCm39)	V620A	possibly damaging	Het
Rbak	A	G	5: 143,162,355 (GRCm39)		probably benign	Het
Rbl2	A	G	8: 91,816,844 (GRCm39)	I401M	probably benign	Het
Rragc	T	C	4: 123,814,852 (GRCm39)	S183P	probably damaging	Het
Septin3	A	G	15: 82,163,814 (GRCm39)		probably benign	Het
Slc22a6	A	T	19: 8,603,578 (GRCm39)		probably benign	Het
Spag4	A	T	2: 155,910,417 (GRCm39)	T348S	probably benign	Het
Sptbn1	T	C	11: 30,054,623 (GRCm39)	R2157G	probably benign	Het
Tmem168	G	A	6: 13,582,940 (GRCm39)	T263M	probably damaging	Het
Tnik	T	A	3: 28,625,007 (GRCm39)		probably null	Het
Tnpo2	T	A	8: 85,777,137 (GRCm39)	V549E	probably damaging	Het
Ttll7	A	C	3: 146,645,776 (GRCm39)	K545Q	possibly damaging	Het
Tubgcp5	T	G	7: 55,449,221 (GRCm39)	D139E	probably benign	Het
Vmn1r233	T	A	17: 21,214,861 (GRCm39)	N30Y	probably damaging	Het
Vmn2r25	T	G	6: 123,829,962 (GRCm39)	D63A	possibly damaging	Het
Vmn2r84	T	C	10: 130,222,148 (GRCm39)	M691V	probably benign	Het
Zc3hc1	A	T	6: 30,372,729 (GRCm39)		probably benign	Het

Other mutations in Vmn2r79

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01401:Vmn2r79	APN	7	86,686,481 (GRCm39)	missense	probably benign	0.01
IGL01675:Vmn2r79	APN	7	86,645,856 (GRCm39)	missense	probably benign	0.01
IGL01760:Vmn2r79	APN	7	86,651,366 (GRCm39)	missense	probably benign
IGL01834:Vmn2r79	APN	7	86,686,354 (GRCm39)	missense	probably benign	0.01
IGL01914:Vmn2r79	APN	7	86,686,571 (GRCm39)	missense	probably benign	0.14
IGL01980:Vmn2r79	APN	7	86,686,290 (GRCm39)	missense	possibly damaging	0.49
IGL02438:Vmn2r79	APN	7	86,651,744 (GRCm39)	missense	probably damaging	0.98
IGL02740:Vmn2r79	APN	7	86,653,366 (GRCm39)	missense	probably benign	0.00
IGL03052:Vmn2r79	UTSW	7	86,652,799 (GRCm39)	missense	probably benign	0.00
PIT4445001:Vmn2r79	UTSW	7	86,651,408 (GRCm39)	missense	possibly damaging	0.46
R0096:Vmn2r79	UTSW	7	86,686,527 (GRCm39)	missense	probably damaging	1.00
R0096:Vmn2r79	UTSW	7	86,686,527 (GRCm39)	missense	probably damaging	1.00
R0270:Vmn2r79	UTSW	7	86,652,594 (GRCm39)	missense	probably benign	0.00
R0336:Vmn2r79	UTSW	7	86,651,287 (GRCm39)	missense	probably benign	0.15
R0418:Vmn2r79	UTSW	7	86,651,611 (GRCm39)	missense	probably benign	0.18
R1070:Vmn2r79	UTSW	7	86,652,681 (GRCm39)	missense	probably damaging	1.00
R1234:Vmn2r79	UTSW	7	86,653,307 (GRCm39)	missense	possibly damaging	0.71
R1459:Vmn2r79	UTSW	7	86,687,002 (GRCm39)	missense	probably benign	0.01
R1513:Vmn2r79	UTSW	7	86,686,652 (GRCm39)	missense	probably benign	0.01
R1624:Vmn2r79	UTSW	7	86,653,247 (GRCm39)	critical splice acceptor site	probably null
R1633:Vmn2r79	UTSW	7	86,687,042 (GRCm39)	missense	possibly damaging	0.52
R1676:Vmn2r79	UTSW	7	86,651,839 (GRCm39)	missense	probably benign
R1781:Vmn2r79	UTSW	7	86,651,555 (GRCm39)	missense	probably benign	0.00
R1794:Vmn2r79	UTSW	7	86,650,621 (GRCm39)	missense	probably benign	0.37
R1823:Vmn2r79	UTSW	7	86,687,080 (GRCm39)	missense	probably damaging	1.00
R2013:Vmn2r79	UTSW	7	86,653,289 (GRCm39)	missense	possibly damaging	0.50
R2018:Vmn2r79	UTSW	7	86,651,634 (GRCm39)	missense	probably benign	0.07
R2019:Vmn2r79	UTSW	7	86,651,634 (GRCm39)	missense	probably benign	0.07
R2177:Vmn2r79	UTSW	7	86,645,839 (GRCm39)	missense	possibly damaging	0.94
R2984:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R3719:Vmn2r79	UTSW	7	86,651,245 (GRCm39)	missense	probably benign	0.05
R3798:Vmn2r79	UTSW	7	86,651,402 (GRCm39)	missense	possibly damaging	0.88
R3969:Vmn2r79	UTSW	7	86,652,801 (GRCm39)	missense	probably damaging	1.00
R4182:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4183:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4245:Vmn2r79	UTSW	7	86,651,624 (GRCm39)	missense	possibly damaging	0.73
R4301:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4391:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4393:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4394:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4396:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4397:Vmn2r79	UTSW	7	86,651,099 (GRCm39)	missense	possibly damaging	0.85
R4592:Vmn2r79	UTSW	7	86,653,319 (GRCm39)	missense	possibly damaging	0.86
R4697:Vmn2r79	UTSW	7	86,687,168 (GRCm39)	missense	probably damaging	0.98
R4897:Vmn2r79	UTSW	7	86,650,675 (GRCm39)	missense	probably benign
R5016:Vmn2r79	UTSW	7	86,686,548 (GRCm39)	missense	probably benign	0.00
R5058:Vmn2r79	UTSW	7	86,651,423 (GRCm39)	missense	probably damaging	0.98
R5177:Vmn2r79	UTSW	7	86,651,177 (GRCm39)	missense	probably damaging	0.97
R6078:Vmn2r79	UTSW	7	86,653,319 (GRCm39)	missense	possibly damaging	0.86
R6079:Vmn2r79	UTSW	7	86,653,319 (GRCm39)	missense	possibly damaging	0.86
R6138:Vmn2r79	UTSW	7	86,653,319 (GRCm39)	missense	possibly damaging	0.86
R6257:Vmn2r79	UTSW	7	86,651,778 (GRCm39)	missense	probably benign	0.27
R6260:Vmn2r79	UTSW	7	86,686,365 (GRCm39)	missense	probably benign	0.00
R6307:Vmn2r79	UTSW	7	86,686,976 (GRCm39)	missense	probably damaging	1.00
R6323:Vmn2r79	UTSW	7	86,650,522 (GRCm39)	missense	probably benign	0.05
R6374:Vmn2r79	UTSW	7	86,651,498 (GRCm39)	missense	probably benign	0.02
R6530:Vmn2r79	UTSW	7	86,651,252 (GRCm39)	missense	possibly damaging	0.91
R6546:Vmn2r79	UTSW	7	86,652,741 (GRCm39)	missense	probably benign	0.01
R6682:Vmn2r79	UTSW	7	86,653,370 (GRCm39)	missense	possibly damaging	0.69
R6858:Vmn2r79	UTSW	7	86,686,580 (GRCm39)	missense	probably benign
R6965:Vmn2r79	UTSW	7	86,651,100 (GRCm39)	missense	probably benign	0.10
R7130:Vmn2r79	UTSW	7	86,651,474 (GRCm39)	missense	probably damaging	0.99
R7156:Vmn2r79	UTSW	7	86,686,851 (GRCm39)	missense	probably damaging	0.98
R7604:Vmn2r79	UTSW	7	86,652,592 (GRCm39)	critical splice acceptor site	probably null
R7691:Vmn2r79	UTSW	7	86,687,111 (GRCm39)	missense	probably damaging	0.96
R8055:Vmn2r79	UTSW	7	86,686,541 (GRCm39)	missense	possibly damaging	0.94
R8070:Vmn2r79	UTSW	7	86,651,336 (GRCm39)	missense	probably benign
R8073:Vmn2r79	UTSW	7	86,651,462 (GRCm39)	missense	probably benign	0.00
R8145:Vmn2r79	UTSW	7	86,686,862 (GRCm39)	missense	probably benign	0.02
R8263:Vmn2r79	UTSW	7	86,686,726 (GRCm39)	missense	possibly damaging	0.89
R8350:Vmn2r79	UTSW	7	86,686,741 (GRCm39)	nonsense	probably null
R8400:Vmn2r79	UTSW	7	86,651,308 (GRCm39)	missense	probably benign	0.00
R8814:Vmn2r79	UTSW	7	86,651,714 (GRCm39)	missense	probably benign	0.00
R8862:Vmn2r79	UTSW	7	86,645,712 (GRCm39)	missense	probably benign	0.23
R9146:Vmn2r79	UTSW	7	86,650,681 (GRCm39)	nonsense	probably null
R9276:Vmn2r79	UTSW	7	86,687,045 (GRCm39)	missense	probably damaging	1.00
R9361:Vmn2r79	UTSW	7	86,652,822 (GRCm39)	critical splice donor site	probably null
R9676:Vmn2r79	UTSW	7	86,686,452 (GRCm39)	missense	probably damaging	1.00
U15987:Vmn2r79	UTSW	7	86,653,319 (GRCm39)	missense	possibly damaging	0.86
X0054:Vmn2r79	UTSW	7	86,653,270 (GRCm39)	missense	probably benign	0.01
Z1088:Vmn2r79	UTSW	7	86,651,549 (GRCm39)	missense	probably damaging	1.00
Z1176:Vmn2r79	UTSW	7	86,686,377 (GRCm39)	missense	probably benign
Z1176:Vmn2r79	UTSW	7	86,651,526 (GRCm39)	missense	probably benign	0.00

Posted On

2014-05-07