Incidental Mutation 'IGL01871:Rhov'
ID178700
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Rhov
Ensembl Gene ENSMUSG00000034226
Gene Nameras homolog family member V
SynonymsArhv, A030005A06Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.205) question?
Stock #IGL01871
Quality Score
Status
Chromosome2
Chromosomal Location119269201-119271272 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 119270738 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Lysine at position 71 (Q71K)
Ref Sequence ENSEMBL: ENSMUSP00000041411 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000037360]
Predicted Effect probably benign
Transcript: ENSMUST00000037360
AA Change: Q71K

PolyPhen 2 Score 0.150 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000041411
Gene: ENSMUSG00000034226
AA Change: Q71K

DomainStartEndE-ValueType
low complexity region 2 30 N/A INTRINSIC
RHO 34 208 3.12e-89 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 A T 13: 81,472,394 probably null Het
Aqp7 G A 4: 41,045,321 R20* probably null Het
Asxl2 G T 12: 3,502,112 V1285L probably benign Het
Bdp1 A T 13: 100,066,053 S688T probably benign Het
Cc2d2a A T 5: 43,688,969 I357F probably damaging Het
Clasp1 A T 1: 118,570,889 I884F probably damaging Het
Cpne4 T G 9: 104,925,757 M200R possibly damaging Het
Cyp2d10 T A 15: 82,403,885 D180V probably damaging Het
Dicer1 A T 12: 104,704,180 V1042D probably damaging Het
Dlc1 G A 8: 36,850,180 T447I probably damaging Het
Efl1 T C 7: 82,763,319 M972T possibly damaging Het
Erbin A G 13: 103,834,766 S781P probably damaging Het
Fam46b A G 4: 133,486,309 I164V possibly damaging Het
Galnt4 G A 10: 99,109,241 G276D probably damaging Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gmppa A G 1: 75,437,017 I41V probably damaging Het
Golga1 C T 2: 39,050,198 probably benign Het
H2-Ob G T 17: 34,242,545 W86L probably damaging Het
Hnrnpr G A 4: 136,339,574 R482H unknown Het
L2hgdh T C 12: 69,722,095 E81G probably damaging Het
Mre11a T C 9: 14,811,897 V389A possibly damaging Het
Mxra8 A G 4: 155,842,801 T372A probably benign Het
Ncapg T A 5: 45,688,581 S593R probably benign Het
Ndufaf1 C T 2: 119,658,287 W250* probably null Het
Neb T C 2: 52,153,069 E6783G probably damaging Het
Nmt2 T C 2: 3,312,674 Y175H probably damaging Het
Olfml2b T C 1: 170,662,355 probably benign Het
Pitpnm3 T A 11: 72,056,138 M812L probably damaging Het
Pou2f3 A G 9: 43,134,473 probably benign Het
Prkdc A G 16: 15,783,087 T2871A probably benign Het
Rapgef4 A G 2: 72,198,360 T392A possibly damaging Het
Slc22a15 T C 3: 101,860,794 probably benign Het
Spaca1 T A 4: 34,040,894 N22Y probably damaging Het
Stmnd1 A G 13: 46,289,713 E107G probably damaging Het
Timm22 T C 11: 76,407,437 V78A probably damaging Het
Usp47 T C 7: 112,077,786 probably benign Het
Utp4 A C 8: 106,912,317 K419T probably benign Het
Zfp410 T C 12: 84,325,791 probably null Het
Other mutations in Rhov
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0732:Rhov UTSW 2 119271014 missense probably damaging 1.00
R1646:Rhov UTSW 2 119271020 missense probably damaging 1.00
R4997:Rhov UTSW 2 119270468 missense probably damaging 1.00
R5124:Rhov UTSW 2 119271087 missense unknown
R5993:Rhov UTSW 2 119270052 missense probably damaging 1.00
R6168:Rhov UTSW 2 119270972 missense probably damaging 1.00
Z1177:Rhov UTSW 2 119270415 nonsense probably null
Posted On2014-05-07