Incidental Mutation 'IGL01871:Zfp410'
| ID |
178732 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp410
|
| Ensembl Gene |
ENSMUSG00000042472 |
| Gene Name |
zinc finger protein 410 |
| Synonyms |
D12Ertd748e |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.197)
|
| Stock # |
IGL01871
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
12 |
| Chromosomal Location |
84363626-84390497 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 84372565 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152817
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045931]
[ENSMUST00000045931]
[ENSMUST00000220931]
[ENSMUST00000221656]
[ENSMUST00000222258]
[ENSMUST00000222606]
[ENSMUST00000222832]
[ENSMUST00000222471]
|
| AlphaFold |
Q8BKX7 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000045931
|
| SMART Domains |
Protein: ENSMUSP00000045550
Gene: ENSMUSG00000042472
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
219 |
243 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
249 |
273 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
279 |
303 |
1.13e-4 |
SMART |
|
ZnF_C2H2
|
309 |
333 |
1.45e-2 |
SMART |
|
ZnF_C2H2
|
339 |
361 |
5.59e-4 |
SMART |
|
low complexity region
|
400 |
417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000045931
|
| SMART Domains |
Protein: ENSMUSP00000045550
Gene: ENSMUSG00000042472
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
219 |
243 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
249 |
273 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
279 |
303 |
1.13e-4 |
SMART |
|
ZnF_C2H2
|
309 |
333 |
1.45e-2 |
SMART |
|
ZnF_C2H2
|
339 |
361 |
5.59e-4 |
SMART |
|
low complexity region
|
400 |
417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000220931
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220955
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000221490
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221656
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000222258
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222431
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222606
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000222832
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000223355
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222471
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222773
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 38 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
A |
T |
13: 81,620,513 (GRCm39) |
|
probably null |
Het |
| Aqp7 |
G |
A |
4: 41,045,321 (GRCm39) |
R20* |
probably null |
Het |
| Asxl2 |
G |
T |
12: 3,552,112 (GRCm39) |
V1285L |
probably benign |
Het |
| Bdp1 |
A |
T |
13: 100,202,561 (GRCm39) |
S688T |
probably benign |
Het |
| Cc2d2a |
A |
T |
5: 43,846,311 (GRCm39) |
I357F |
probably damaging |
Het |
| Clasp1 |
A |
T |
1: 118,498,619 (GRCm39) |
I884F |
probably damaging |
Het |
| Cpne4 |
T |
G |
9: 104,802,956 (GRCm39) |
M200R |
possibly damaging |
Het |
| Cyp2d10 |
T |
A |
15: 82,288,086 (GRCm39) |
D180V |
probably damaging |
Het |
| Dicer1 |
A |
T |
12: 104,670,439 (GRCm39) |
V1042D |
probably damaging |
Het |
| Dlc1 |
G |
A |
8: 37,317,334 (GRCm39) |
T447I |
probably damaging |
Het |
| Efl1 |
T |
C |
7: 82,412,527 (GRCm39) |
M972T |
possibly damaging |
Het |
| Erbin |
A |
G |
13: 103,971,274 (GRCm39) |
S781P |
probably damaging |
Het |
| Galnt4 |
G |
A |
10: 98,945,103 (GRCm39) |
G276D |
probably damaging |
Het |
| Gm10718 |
A |
T |
9: 3,025,118 (GRCm39) |
Y194F |
probably benign |
Het |
| Gmppa |
A |
G |
1: 75,413,661 (GRCm39) |
I41V |
probably damaging |
Het |
| Golga1 |
C |
T |
2: 38,940,210 (GRCm39) |
|
probably benign |
Het |
| H2-Ob |
G |
T |
17: 34,461,519 (GRCm39) |
W86L |
probably damaging |
Het |
| Hnrnpr |
G |
A |
4: 136,066,885 (GRCm39) |
R482H |
unknown |
Het |
| L2hgdh |
T |
C |
12: 69,768,869 (GRCm39) |
E81G |
probably damaging |
Het |
| Mre11a |
T |
C |
9: 14,723,193 (GRCm39) |
V389A |
possibly damaging |
Het |
| Mxra8 |
A |
G |
4: 155,927,258 (GRCm39) |
T372A |
probably benign |
Het |
| Ncapg |
T |
A |
5: 45,845,923 (GRCm39) |
S593R |
probably benign |
Het |
| Ndufaf1 |
C |
T |
2: 119,488,768 (GRCm39) |
W250* |
probably null |
Het |
| Neb |
T |
C |
2: 52,043,081 (GRCm39) |
E6783G |
probably damaging |
Het |
| Nmt2 |
T |
C |
2: 3,313,711 (GRCm39) |
Y175H |
probably damaging |
Het |
| Olfml2b |
T |
C |
1: 170,489,924 (GRCm39) |
|
probably benign |
Het |
| Pitpnm3 |
T |
A |
11: 71,946,964 (GRCm39) |
M812L |
probably damaging |
Het |
| Pou2f3 |
A |
G |
9: 43,045,768 (GRCm39) |
|
probably benign |
Het |
| Prkdc |
A |
G |
16: 15,600,951 (GRCm39) |
T2871A |
probably benign |
Het |
| Rapgef4 |
A |
G |
2: 72,028,704 (GRCm39) |
T392A |
possibly damaging |
Het |
| Rhov |
G |
T |
2: 119,101,219 (GRCm39) |
Q71K |
probably benign |
Het |
| Slc22a15 |
T |
C |
3: 101,768,110 (GRCm39) |
|
probably benign |
Het |
| Spaca1 |
T |
A |
4: 34,040,894 (GRCm39) |
N22Y |
probably damaging |
Het |
| Stmnd1 |
A |
G |
13: 46,443,189 (GRCm39) |
E107G |
probably damaging |
Het |
| Tent5b |
A |
G |
4: 133,213,620 (GRCm39) |
I164V |
possibly damaging |
Het |
| Timm22 |
T |
C |
11: 76,298,263 (GRCm39) |
V78A |
probably damaging |
Het |
| Usp47 |
T |
C |
7: 111,676,993 (GRCm39) |
|
probably benign |
Het |
| Utp4 |
A |
C |
8: 107,638,949 (GRCm39) |
K419T |
probably benign |
Het |
|
| Other mutations in Zfp410 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01782:Zfp410
|
APN |
12 |
84,374,048 (GRCm39) |
splice site |
probably benign |
|
|
IGL02152:Zfp410
|
APN |
12 |
84,379,702 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02702:Zfp410
|
APN |
12 |
84,372,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Zfp410
|
APN |
12 |
84,378,594 (GRCm39) |
splice site |
probably null |
|
|
R0453:Zfp410
|
UTSW |
12 |
84,378,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1525:Zfp410
|
UTSW |
12 |
84,369,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1569:Zfp410
|
UTSW |
12 |
84,379,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Zfp410
|
UTSW |
12 |
84,372,494 (GRCm39) |
missense |
probably benign |
|
|
R2263:Zfp410
|
UTSW |
12 |
84,369,794 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2878:Zfp410
|
UTSW |
12 |
84,378,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3941:Zfp410
|
UTSW |
12 |
84,385,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4880:Zfp410
|
UTSW |
12 |
84,384,449 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4969:Zfp410
|
UTSW |
12 |
84,378,582 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5893:Zfp410
|
UTSW |
12 |
84,384,385 (GRCm39) |
splice site |
probably null |
|
|
R5981:Zfp410
|
UTSW |
12 |
84,378,414 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6268:Zfp410
|
UTSW |
12 |
84,378,612 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7318:Zfp410
|
UTSW |
12 |
84,372,464 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7599:Zfp410
|
UTSW |
12 |
84,378,630 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8357:Zfp410
|
UTSW |
12 |
84,374,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8457:Zfp410
|
UTSW |
12 |
84,374,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Posted On |
2014-05-07 |
Incidental Mutation