Incidental Mutation 'IGL01886:Sult6b2'
ID 179156
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult6b2
Ensembl Gene ENSMUSG00000048473
Gene Name sulfotransferase family 6B, member 2
Synonyms LOC330440, Gm766
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.098) question?
Stock # IGL01886
Quality Score
Status
Chromosome 6
Chromosomal Location 142785204-142804502 bp(-) (GRCm38)
Type of Mutation critical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to G at 142790126 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000107398 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000111768] [ENSMUST00000156662]
AlphaFold B7ZWN4
Predicted Effect probably null
Transcript: ENSMUST00000111768
SMART Domains Protein: ENSMUSP00000107398
Gene: ENSMUSG00000048473

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 37 276 1.5e-64 PFAM
Pfam:Sulfotransfer_3 38 200 1.6e-10 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000156662
SMART Domains Protein: ENSMUSP00000138527
Gene: ENSMUSG00000048473

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 74 157 5.6e-21 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akt1 C T 12: 112,659,158 V136M probably benign Het
Ankrd34c A T 9: 89,730,265 L8M possibly damaging Het
Anks6 C A 4: 47,044,850 W352L probably damaging Het
Arhgap12 A T 18: 6,027,613 N768K probably damaging Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
Clec7a A T 6: 129,463,177 probably benign Het
Cyp3a13 G A 5: 137,898,820 P411S probably damaging Het
Elavl2 A G 4: 91,264,093 V129A probably damaging Het
Ercc6 T A 14: 32,569,580 S994T possibly damaging Het
Esco1 T A 18: 10,595,262 K8I probably damaging Het
Esr1 T A 10: 4,856,861 I259K probably damaging Het
Filip1l A G 16: 57,571,250 I734V possibly damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Grin3a T A 4: 49,702,814 I891F probably damaging Het
Kat7 T C 11: 95,306,133 T27A probably benign Het
Kdm1a A G 4: 136,561,016 probably null Het
Kifc5b T C 17: 26,932,117 V663A probably damaging Het
Lama1 T G 17: 67,807,797 S2314A probably benign Het
Lrrc69 C T 4: 14,703,984 V279I probably benign Het
Mast3 A T 8: 70,782,139 L774Q possibly damaging Het
Med27 C A 2: 29,413,482 P9Q probably damaging Het
Myo5a C A 9: 75,169,090 probably benign Het
Myoz1 T C 14: 20,655,309 K14E probably damaging Het
Neb T C 2: 52,183,845 probably benign Het
Nlrp1a T C 11: 71,123,501 T308A probably benign Het
Olfr364-ps1 A G 2: 37,146,509 Y99C probably damaging Het
Olfr926 G T 9: 38,877,548 C124F probably damaging Het
Orc1 T A 4: 108,603,957 probably null Het
Pnkp G A 7: 44,862,207 A76T probably damaging Het
Polr3h T C 15: 81,917,390 E95G probably damaging Het
Prpf40b T A 15: 99,304,447 M62K unknown Het
Prpf8 C A 11: 75,495,744 Q1075K probably benign Het
Ptprg A G 14: 12,179,280 K766E probably benign Het
Rabgap1l A T 1: 160,342,042 N778K probably damaging Het
Riok3 T A 18: 12,139,385 N204K probably damaging Het
Shank3 A G 15: 89,531,663 K650E probably damaging Het
Sim1 T A 10: 50,984,315 S758T probably damaging Het
Slu7 T G 11: 43,439,260 N171K probably damaging Het
Taf6l C T 19: 8,778,086 probably null Het
Ubtfl1 G A 9: 18,409,721 V182M possibly damaging Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Other mutations in Sult6b2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00436:Sult6b2 APN 6 142797837 splice site probably benign
IGL00694:Sult6b2 APN 6 142790289 missense possibly damaging 0.92
IGL01146:Sult6b2 APN 6 142804308 missense probably benign 0.00
IGL02385:Sult6b2 APN 6 142801772 missense probably benign 0.01
IGL02477:Sult6b2 APN 6 142801721 missense probably damaging 1.00
R0088:Sult6b2 UTSW 6 142797949 missense probably damaging 1.00
R2850:Sult6b2 UTSW 6 142797887 missense probably benign 0.18
R4015:Sult6b2 UTSW 6 142790262 missense possibly damaging 0.89
R4667:Sult6b2 UTSW 6 142801695 nonsense probably null
R5172:Sult6b2 UTSW 6 142797931 missense probably damaging 1.00
R5973:Sult6b2 UTSW 6 142790295 missense probably benign 0.01
R6152:Sult6b2 UTSW 6 142804376 missense probably benign 0.00
R6893:Sult6b2 UTSW 6 142804299 missense possibly damaging 0.63
R7667:Sult6b2 UTSW 6 142786359 missense probably benign 0.10
R7853:Sult6b2 UTSW 6 142801798 missense not run
R8071:Sult6b2 UTSW 6 142790142 missense probably damaging 1.00
R8225:Sult6b2 UTSW 6 142804329 missense probably benign 0.00
R8344:Sult6b2 UTSW 6 142790296 missense probably benign 0.13
Posted On 2014-05-07