Incidental Mutation 'IGL01890:Vmn1r194'
ID 179221
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r194
Ensembl Gene ENSMUSG00000069297
Gene Name vomeronasal 1 receptor 194
Synonyms Gm11294
Accession Numbers
Essential gene? Probably non essential (E-score: 0.060) question?
Stock # IGL01890
Quality Score
Status
Chromosome 13
Chromosomal Location 22428385-22429275 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to T at 22428776 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Tyrosine to Phenylalanine at position 131 (Y131F)
Ref Sequence ENSEMBL: ENSMUSP00000089331 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000091737]
AlphaFold J3JS27
Predicted Effect probably benign
Transcript: ENSMUST00000091737
AA Change: Y131F

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
SMART Domains Protein: ENSMUSP00000089331
Gene: ENSMUSG00000069297
AA Change: Y131F

DomainStartEndE-ValueType
Pfam:V1R 35 296 3.4e-37 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 22 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Actn1 A T 12: 80,231,642 (GRCm39) V265E probably damaging Het
Anks1b A G 10: 90,480,389 (GRCm39) I865V probably benign Het
Car5a G A 8: 122,650,349 (GRCm39) A182V probably benign Het
Ccdc47 A G 11: 106,096,277 (GRCm39) V249A probably damaging Het
Cyb561d2 A G 9: 107,418,722 (GRCm39) V34A probably damaging Het
Dmbt1 A G 7: 130,676,149 (GRCm39) probably benign Het
Entpd6 G A 2: 150,612,612 (GRCm39) D445N possibly damaging Het
Fastkd2 A G 1: 63,771,320 (GRCm39) I225M probably benign Het
Flcn A G 11: 59,685,996 (GRCm39) V424A probably benign Het
Gm10718 A T 9: 3,025,118 (GRCm39) Y194F probably benign Het
Gpn3 A G 5: 122,519,328 (GRCm39) M176V probably benign Het
Igkv12-38 C T 6: 69,920,389 (GRCm39) C43Y probably damaging Het
Oas1h A G 5: 121,000,852 (GRCm39) probably null Het
Rexo1 A T 10: 80,378,845 (GRCm39) Y1064N possibly damaging Het
Skint1 G A 4: 111,867,878 (GRCm39) G2R probably damaging Het
Slc4a9 G A 18: 36,662,760 (GRCm39) A172T possibly damaging Het
Synpo2 A G 3: 122,906,146 (GRCm39) S727P probably damaging Het
Tmem131 A T 1: 36,862,237 (GRCm39) probably benign Het
Trpm3 G T 19: 22,689,083 (GRCm39) R4L probably damaging Het
Upf1 A T 8: 70,786,880 (GRCm39) V879E possibly damaging Het
Vmn2r129 C T 4: 156,690,549 (GRCm39) noncoding transcript Het
Vmn2r95 T A 17: 18,671,737 (GRCm39) N491K probably damaging Het
Other mutations in Vmn1r194
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02140:Vmn1r194 APN 13 22,428,706 (GRCm39) missense probably benign 0.08
R0066:Vmn1r194 UTSW 13 22,428,641 (GRCm39) missense probably benign 0.33
R0066:Vmn1r194 UTSW 13 22,428,641 (GRCm39) missense probably benign 0.33
R0109:Vmn1r194 UTSW 13 22,429,217 (GRCm39) missense probably damaging 1.00
R0109:Vmn1r194 UTSW 13 22,429,217 (GRCm39) missense probably damaging 1.00
R1276:Vmn1r194 UTSW 13 22,429,031 (GRCm39) missense probably damaging 1.00
R1426:Vmn1r194 UTSW 13 22,429,236 (GRCm39) missense probably damaging 0.99
R1620:Vmn1r194 UTSW 13 22,429,133 (GRCm39) missense probably damaging 1.00
R4593:Vmn1r194 UTSW 13 22,428,461 (GRCm39) missense possibly damaging 0.60
R4844:Vmn1r194 UTSW 13 22,429,223 (GRCm39) missense probably benign 0.02
R5011:Vmn1r194 UTSW 13 22,429,058 (GRCm39) missense probably benign 0.00
R5110:Vmn1r194 UTSW 13 22,429,170 (GRCm39) missense probably benign 0.07
R5588:Vmn1r194 UTSW 13 22,428,512 (GRCm39) missense possibly damaging 0.75
R5810:Vmn1r194 UTSW 13 22,428,597 (GRCm39) nonsense probably null
R6648:Vmn1r194 UTSW 13 22,428,694 (GRCm39) missense probably benign 0.11
R7660:Vmn1r194 UTSW 13 22,428,767 (GRCm39) missense not run
R7663:Vmn1r194 UTSW 13 22,428,911 (GRCm39) missense not run
R7879:Vmn1r194 UTSW 13 22,428,772 (GRCm39) missense probably benign 0.06
R8344:Vmn1r194 UTSW 13 22,429,247 (GRCm39) missense probably benign 0.01
R8830:Vmn1r194 UTSW 13 22,429,006 (GRCm39) missense possibly damaging 0.88
R9245:Vmn1r194 UTSW 13 22,428,731 (GRCm39) missense probably benign 0.44
R9291:Vmn1r194 UTSW 13 22,428,875 (GRCm39) missense probably benign 0.20
R9624:Vmn1r194 UTSW 13 22,428,671 (GRCm39) missense probably damaging 1.00
Z1176:Vmn1r194 UTSW 13 22,428,596 (GRCm39) missense probably benign 0.08
Posted On 2014-05-07