Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01890:Vmn1r194'

179221

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r194

Ensembl Gene

ENSMUSG00000069297

Gene Name

vomeronasal 1 receptor 194

Synonyms

Gm11294

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL01890

Quality Score

Status

Chromosome

Chromosomal Location

22244215-22245105 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 22244606 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Phenylalanine at position 131 (Y131F)

Ref Sequence

ENSEMBL: ENSMUSP00000089331 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000091737]

AlphaFold

J3JS27

Predicted Effect

probably benign
Transcript: ENSMUST00000091737
AA Change: Y131F

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000089331
Gene: ENSMUSG00000069297
AA Change: Y131F

Domain	Start	End	E-Value	Type
Pfam:V1R	35	296	3.4e-37	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 22 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actn1	A	T	12: 80,184,868	V265E	probably damaging	Het
Anks1b	A	G	10: 90,644,527	I865V	probably benign	Het
Car5a	G	A	8: 121,923,610	A182V	probably benign	Het
Ccdc47	A	G	11: 106,205,451	V249A	probably damaging	Het
Cyb561d2	A	G	9: 107,541,523	V34A	probably damaging	Het
Dmbt1	A	G	7: 131,074,419		probably benign	Het
Entpd6	G	A	2: 150,770,692	D445N	possibly damaging	Het
Fastkd2	A	G	1: 63,732,161	I225M	probably benign	Het
Flcn	A	G	11: 59,795,170	V424A	probably benign	Het
Gm10718	A	T	9: 3,025,118	Y194F	probably benign	Het
Gpn3	A	G	5: 122,381,265	M176V	probably benign	Het
Igkv12-38	C	T	6: 69,943,405	C43Y	probably damaging	Het
Oas1h	A	G	5: 120,862,789		probably null	Het
Rexo1	A	T	10: 80,543,011	Y1064N	possibly damaging	Het
Skint1	G	A	4: 112,010,681	G2R	probably damaging	Het
Slc4a9	G	A	18: 36,529,707	A172T	possibly damaging	Het
Synpo2	A	G	3: 123,112,497	S727P	probably damaging	Het
Tmem131	A	T	1: 36,823,156		probably benign	Het
Trpm3	G	T	19: 22,711,719	R4L	probably damaging	Het
Upf1	A	T	8: 70,334,230	V879E	possibly damaging	Het
Vmn2r95	T	A	17: 18,451,475	N491K	probably damaging	Het
Vmn2r-ps159	C	T	4: 156,338,254		noncoding transcript	Het

Other mutations in Vmn1r194

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02140:Vmn1r194	APN	13	22244536	missense	probably benign	0.08
R0066:Vmn1r194	UTSW	13	22244471	missense	probably benign	0.33
R0066:Vmn1r194	UTSW	13	22244471	missense	probably benign	0.33
R0109:Vmn1r194	UTSW	13	22245047	missense	probably damaging	1.00
R0109:Vmn1r194	UTSW	13	22245047	missense	probably damaging	1.00
R1276:Vmn1r194	UTSW	13	22244861	missense	probably damaging	1.00
R1426:Vmn1r194	UTSW	13	22245066	missense	probably damaging	0.99
R1620:Vmn1r194	UTSW	13	22244963	missense	probably damaging	1.00
R4593:Vmn1r194	UTSW	13	22244291	missense	possibly damaging	0.60
R4844:Vmn1r194	UTSW	13	22245053	missense	probably benign	0.02
R5011:Vmn1r194	UTSW	13	22244888	missense	probably benign	0.00
R5110:Vmn1r194	UTSW	13	22245000	missense	probably benign	0.07
R5588:Vmn1r194	UTSW	13	22244342	missense	possibly damaging	0.75
R5810:Vmn1r194	UTSW	13	22244427	nonsense	probably null
R6648:Vmn1r194	UTSW	13	22244524	missense	probably benign	0.11
R7660:Vmn1r194	UTSW	13	22244597	missense	not run
R7663:Vmn1r194	UTSW	13	22244741	missense	not run
R7879:Vmn1r194	UTSW	13	22244602	missense	probably benign	0.06
R8344:Vmn1r194	UTSW	13	22245077	missense	probably benign	0.01
R8830:Vmn1r194	UTSW	13	22244836	missense	possibly damaging	0.88
R9245:Vmn1r194	UTSW	13	22244561	missense	probably benign	0.44
R9291:Vmn1r194	UTSW	13	22244705	missense	probably benign	0.20
R9624:Vmn1r194	UTSW	13	22244501	missense	probably damaging	1.00
Z1176:Vmn1r194	UTSW	13	22244426	missense	probably benign	0.08

Posted On

2014-05-07