Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01892:Vmn2r9'

179259

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r9

Ensembl Gene

ENSMUSG00000091624

Gene Name

vomeronasal 2, receptor 9

Synonyms

EG435864

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.113) question?

Stock #

IGL01892

Quality Score

Status

Chromosome

Chromosomal Location

108990813-109000376 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 108995700 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 316 (V316D)

Ref Sequence

ENSEMBL: ENSMUSP00000129520 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170419]

AlphaFold

K7N6Z8

Predicted Effect

probably damaging
Transcript: ENSMUST00000170419
AA Change: V316D

PolyPhen 2 Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000129520
Gene: ENSMUSG00000091624
AA Change: V316D

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
Pfam:ANF_receptor	77	412	8.1e-29	PFAM
Pfam:NCD3G	507	561	2.3e-16	PFAM
Pfam:7tm_3	592	829	3.4e-54	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000176157

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Cplane1	A	T	15: 8,271,749 (GRCm39)		probably benign	Het
Cyp2c68	T	A	19: 39,722,788 (GRCm39)	E253D	probably benign	Het
Gbp2b	A	G	3: 142,309,381 (GRCm39)	D164G	probably benign	Het
Gm10717	C	T	9: 3,025,616 (GRCm39)	S67L	probably benign	Het
Gm21738	G	A	14: 19,416,979 (GRCm38)	S144L	probably benign	Het
Lct	G	T	1: 128,235,342 (GRCm39)	T555N	probably damaging	Het
Ncam2	T	A	16: 81,386,587 (GRCm39)	H655Q	possibly damaging	Het
Or52a24	A	T	7: 103,381,687 (GRCm39)	M185L	possibly damaging	Het
Or8b57	C	A	9: 40,004,114 (GRCm39)	L45F	probably damaging	Het
Pglyrp4	A	G	3: 90,646,348 (GRCm39)	N293S	probably benign	Het
Pofut2	C	A	10: 77,101,717 (GRCm39)	D251E	probably benign	Het
Prdm2	T	C	4: 142,860,974 (GRCm39)	E772G	probably damaging	Het
Prkd3	A	T	17: 79,279,930 (GRCm39)	D254E	probably benign	Het
Prr36	G	A	8: 4,265,243 (GRCm39)	P169L	probably damaging	Het
Pwp2	T	C	10: 78,014,841 (GRCm39)	Y381C	probably damaging	Het
Rasgrp1	G	A	2: 117,124,323 (GRCm39)	T293M	probably damaging	Het
Snd1	G	A	6: 28,888,123 (GRCm39)		probably null	Het
Suclg2	A	T	6: 95,556,169 (GRCm39)	D237E	probably damaging	Het
Tenm3	T	C	8: 48,729,431 (GRCm39)	N1509S	probably benign	Het
Thbd	A	T	2: 148,248,988 (GRCm39)	H293Q	possibly damaging	Het
Tie1	T	A	4: 118,333,115 (GRCm39)	Y871F	probably benign	Het
Vmn1r38	A	T	6: 66,753,360 (GRCm39)	V252D	probably benign	Het
Vmn1r60	C	A	7: 5,547,309 (GRCm39)	V264F	probably benign	Het
Vmn1r68	T	C	7: 10,261,334 (GRCm39)	T255A	possibly damaging	Het
Vmn2r49	A	T	7: 9,718,690 (GRCm39)	V458E	probably benign	Het
Wfdc15b	A	T	2: 164,057,388 (GRCm39)	M1K	probably null	Het

Other mutations in Vmn2r9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00920:Vmn2r9	APN	5	108,995,890 (GRCm39)	missense	possibly damaging	0.79
IGL00972:Vmn2r9	APN	5	108,996,903 (GRCm39)	missense	probably benign	0.02
IGL01102:Vmn2r9	APN	5	108,990,811 (GRCm39)	splice site	probably null
IGL02086:Vmn2r9	APN	5	108,995,433 (GRCm39)	missense	probably damaging	1.00
IGL02118:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02119:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02120:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02121:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02123:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02131:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02132:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02171:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02185:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02186:Vmn2r9	APN	5	108,991,502 (GRCm39)	missense	probably damaging	1.00
IGL02346:Vmn2r9	APN	5	108,990,850 (GRCm39)	missense	probably benign	0.07
IGL02508:Vmn2r9	APN	5	108,996,067 (GRCm39)	missense	possibly damaging	0.70
IGL02815:Vmn2r9	APN	5	108,990,856 (GRCm39)	missense	possibly damaging	0.69
IGL03077:Vmn2r9	APN	5	108,996,173 (GRCm39)	splice site	probably benign
IGL03269:Vmn2r9	APN	5	108,995,820 (GRCm39)	missense	probably damaging	1.00
IGL03293:Vmn2r9	APN	5	108,995,997 (GRCm39)	missense	probably damaging	1.00
R0112:Vmn2r9	UTSW	5	108,990,991 (GRCm39)	missense	probably damaging	1.00
R0328:Vmn2r9	UTSW	5	108,995,405 (GRCm39)	missense	probably benign	0.11
R0382:Vmn2r9	UTSW	5	108,995,463 (GRCm39)	missense	probably damaging	1.00
R0521:Vmn2r9	UTSW	5	108,996,154 (GRCm39)	nonsense	probably null
R0975:Vmn2r9	UTSW	5	108,991,169 (GRCm39)	missense	probably damaging	1.00
R1216:Vmn2r9	UTSW	5	108,995,440 (GRCm39)	missense	probably damaging	1.00
R1458:Vmn2r9	UTSW	5	108,996,850 (GRCm39)	missense	probably benign	0.44
R1469:Vmn2r9	UTSW	5	108,991,694 (GRCm39)	missense	probably benign
R1469:Vmn2r9	UTSW	5	108,991,694 (GRCm39)	missense	probably benign
R1704:Vmn2r9	UTSW	5	108,994,266 (GRCm39)	missense	probably damaging	1.00
R1967:Vmn2r9	UTSW	5	108,995,388 (GRCm39)	missense	probably benign	0.03
R1991:Vmn2r9	UTSW	5	108,994,305 (GRCm39)	missense	probably damaging	0.99
R2410:Vmn2r9	UTSW	5	108,996,123 (GRCm39)	missense	probably damaging	1.00
R3419:Vmn2r9	UTSW	5	108,994,299 (GRCm39)	missense	probably damaging	0.96
R3852:Vmn2r9	UTSW	5	108,995,997 (GRCm39)	missense	probably damaging	1.00
R3873:Vmn2r9	UTSW	5	108,995,701 (GRCm39)	missense	probably benign	0.14
R3905:Vmn2r9	UTSW	5	108,995,785 (GRCm39)	missense	probably benign	0.37
R3908:Vmn2r9	UTSW	5	108,995,785 (GRCm39)	missense	probably benign	0.37
R3921:Vmn2r9	UTSW	5	108,996,921 (GRCm39)	missense	probably benign
R4156:Vmn2r9	UTSW	5	108,995,743 (GRCm39)	missense	possibly damaging	0.64
R4477:Vmn2r9	UTSW	5	108,994,143 (GRCm39)	missense	probably benign
R4478:Vmn2r9	UTSW	5	108,994,143 (GRCm39)	missense	probably benign
R4544:Vmn2r9	UTSW	5	108,995,551 (GRCm39)	missense	probably benign	0.00
R4546:Vmn2r9	UTSW	5	108,995,551 (GRCm39)	missense	probably benign	0.00
R4627:Vmn2r9	UTSW	5	108,995,463 (GRCm39)	missense	probably damaging	1.00
R5215:Vmn2r9	UTSW	5	108,994,351 (GRCm39)	missense	probably benign	0.03
R5361:Vmn2r9	UTSW	5	108,995,929 (GRCm39)	missense	probably damaging	1.00
R5587:Vmn2r9	UTSW	5	108,995,427 (GRCm39)	missense	probably damaging	1.00
R6054:Vmn2r9	UTSW	5	108,996,126 (GRCm39)	missense	probably damaging	0.99
R6106:Vmn2r9	UTSW	5	108,992,902 (GRCm39)	missense	probably benign
R6125:Vmn2r9	UTSW	5	108,990,836 (GRCm39)	missense	probably benign	0.01
R6137:Vmn2r9	UTSW	5	108,996,882 (GRCm39)	missense	probably benign	0.00
R6920:Vmn2r9	UTSW	5	108,996,912 (GRCm39)	missense	possibly damaging	0.72
R7579:Vmn2r9	UTSW	5	108,992,948 (GRCm39)	missense	probably damaging	1.00
R8683:Vmn2r9	UTSW	5	108,996,873 (GRCm39)	missense	probably benign
R8964:Vmn2r9	UTSW	5	108,996,031 (GRCm39)	missense	probably benign	0.05
R9022:Vmn2r9	UTSW	5	108,992,923 (GRCm39)	missense	possibly damaging	0.90
R9118:Vmn2r9	UTSW	5	108,990,937 (GRCm39)	missense	probably damaging	0.99
R9125:Vmn2r9	UTSW	5	108,996,047 (GRCm39)	missense
R9240:Vmn2r9	UTSW	5	108,996,099 (GRCm39)	missense	possibly damaging	0.78
R9327:Vmn2r9	UTSW	5	108,996,841 (GRCm39)	missense	probably damaging	0.96
R9412:Vmn2r9	UTSW	5	108,991,484 (GRCm39)	missense	probably damaging	1.00
R9499:Vmn2r9	UTSW	5	108,995,584 (GRCm39)	missense	probably damaging	1.00
R9757:Vmn2r9	UTSW	5	108,995,908 (GRCm39)	missense	possibly damaging	0.87
R9790:Vmn2r9	UTSW	5	108,995,409 (GRCm39)	missense	probably damaging	0.99
R9791:Vmn2r9	UTSW	5	108,995,409 (GRCm39)	missense	probably damaging	0.99

Posted On

2014-05-07