Incidental Mutation 'IGL01893:Vmn2r33'
ID179281
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r33
Ensembl Gene ENSMUSG00000096691
Gene Namevomeronasal 2, receptor 33
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01893
Quality Score
Status
Chromosome7
Chromosomal Location7550967-7566786 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 7563777 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Threonine at position 112 (I112T)
Ref Sequence ENSEMBL: ENSMUSP00000129960 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000165921]
Predicted Effect probably benign
Transcript: ENSMUST00000165921
AA Change: I112T

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000129960
Gene: ENSMUSG00000096691
AA Change: I112T

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 73 469 4.2e-34 PFAM
Pfam:NCD3G 512 565 4.1e-19 PFAM
Pfam:7tm_3 598 833 3.1e-55 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Agl T A 3: 116,788,549 I275F probably damaging Het
Avil G A 10: 127,020,546 E815K possibly damaging Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
Car9 T A 4: 43,510,252 I278N probably damaging Het
Cast T A 13: 74,727,289 K480* probably null Het
Cenpj A G 14: 56,553,474 F373L probably damaging Het
Cspp1 T C 1: 10,134,141 probably null Het
Diaph3 G A 14: 86,918,852 T675I possibly damaging Het
Dip2b A T 15: 100,171,220 probably benign Het
Dnah1 T C 14: 31,266,470 D3425G probably damaging Het
Dolk A G 2: 30,285,914 Y40H probably benign Het
Drosha T C 15: 12,866,650 probably benign Het
Dusp15 A G 2: 152,949,036 probably null Het
Edrf1 T C 7: 133,657,102 F770L probably benign Het
Gabra1 T C 11: 42,133,759 K363R possibly damaging Het
Glipr1l1 A C 10: 112,076,169 T203P probably benign Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
H2-Q10 T C 17: 35,473,271 S270P probably damaging Het
Hipk2 A T 6: 38,818,395 M313K probably benign Het
Htt T A 5: 34,876,830 I1920N probably damaging Het
Lsr A T 7: 30,962,232 V210E possibly damaging Het
Mbtd1 A T 11: 93,921,412 I181L probably null Het
Mettl16 A T 11: 74,805,271 T273S possibly damaging Het
Mlst8 T C 17: 24,477,987 N74D probably benign Het
Nek9 A G 12: 85,336,400 I102T probably damaging Het
Nme7 C T 1: 164,345,281 A187V probably damaging Het
Nphp1 A T 2: 127,769,644 W261R probably damaging Het
Olfr1148 G T 2: 87,833,863 G275* probably null Het
Olfr1306 A T 2: 111,912,244 S229T possibly damaging Het
Olfr90 A G 17: 37,085,868 L99P probably damaging Het
Orc6 A G 8: 85,307,643 D165G probably damaging Het
Ovca2 A G 11: 75,178,307 S89P probably benign Het
Pcdhb12 T G 18: 37,437,210 S470A probably benign Het
Phactr2 T C 10: 13,247,188 T397A probably benign Het
Pms2 T C 5: 143,923,519 L50P probably damaging Het
Prr36 G A 8: 4,215,243 P169L probably damaging Het
Serpinb11 C A 1: 107,377,657 S254R probably benign Het
Serpinb11 C A 1: 107,377,658 Q255K probably benign Het
Skap2 T C 6: 51,874,576 T79A probably damaging Het
Tbx19 A T 1: 165,140,198 S327T possibly damaging Het
Themis3 A G 17: 66,559,627 L206P possibly damaging Het
Tmem132c T A 5: 127,463,029 L373Q possibly damaging Het
Unc13c G T 9: 73,693,366 N1365K probably benign Het
Vmn2r106 A T 17: 20,277,468 M503K probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Vps13a A C 19: 16,663,775 W2328G probably damaging Het
Other mutations in Vmn2r33
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1147:Vmn2r33 UTSW 7 7554145 missense probably benign 0.16
R1147:Vmn2r33 UTSW 7 7554145 missense probably benign 0.16
R3966:Vmn2r33 UTSW 7 7554169 missense probably benign 0.00
R4408:Vmn2r33 UTSW 7 7551230 missense probably damaging 1.00
R6571:Vmn2r33 UTSW 7 7563669 missense probably benign 0.00
R6783:Vmn2r33 UTSW 7 7563798 missense probably benign
R7180:Vmn2r33 UTSW 7 7563897 missense probably benign 0.00
R7984:Vmn2r33 UTSW 7 7563863 missense probably benign 0.01
R8202:Vmn2r33 UTSW 7 7554154 missense possibly damaging 0.87
Posted On2014-05-07