Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01895:Vmn1r19'

179347

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r19

Ensembl Gene

ENSMUSG00000115799

Gene Name

vomeronasal 1 receptor 19

Synonyms

V1rc27

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.100) question?

Stock #

IGL01895

Quality Score

Status

Chromosome

Chromosomal Location

57403780-57406034 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 57405260 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Leucine at position 266 (Q266L)

Ref Sequence

ENSEMBL: ENSMUSP00000087264 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000089830]

AlphaFold

Q8R2C7

Predicted Effect

probably benign
Transcript: ENSMUST00000089830
AA Change: Q266L

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000087264
Gene: ENSMUSG00000115799
AA Change: Q266L

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	6.6e-58	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410089E03Rik	T	A	15: 8,229,107	V2279E	possibly damaging	Het
Abcc6	A	T	7: 46,029,058	I56N	possibly damaging	Het
Akr1c13	A	T	13: 4,205,373	E321V	possibly damaging	Het
Atp8b3	A	T	10: 80,521,828	V1119D	possibly damaging	Het
Cacna1e	G	T	1: 154,443,900	F1351L	probably damaging	Het
Cadps2	A	G	6: 23,427,275	W585R	probably damaging	Het
Ccdc113	C	T	8: 95,536,458		probably benign	Het
Ccer1	A	T	10: 97,694,050	I192F	unknown	Het
Chd8	T	C	14: 52,199,094	N90S	probably benign	Het
Clca3a1	A	T	3: 144,747,572	C463*	probably null	Het
Cyp2c65	T	A	19: 39,072,232	C179S	possibly damaging	Het
Dennd4b	A	G	3: 90,275,567	Q35R	probably benign	Het
Enpep	T	C	3: 129,270,334	E928G	possibly damaging	Het
Fem1c	T	C	18: 46,505,562	T458A	probably benign	Het
Fezf2	A	T	14: 12,342,498	*456R	probably null	Het
Gm10718	A	T	9: 3,025,118	Y194F	probably benign	Het
Gm14085	A	C	2: 122,525,091	Y588S	possibly damaging	Het
Gm21738	G	A	14: 19,416,979	S144L	probably benign	Het
Iqcm	T	G	8: 75,888,560	L423R	probably damaging	Het
Kcnc4	C	A	3: 107,448,218	V305L	probably benign	Het
Kif1a	G	A	1: 93,025,733	T1337I	possibly damaging	Het
Lpxn	A	G	19: 12,833,086	D298G	probably damaging	Het
Lypd8	A	G	11: 58,390,220	T203A	possibly damaging	Het
Mrps28	C	T	3: 8,900,059	V107M	probably damaging	Het
Myo15b	A	G	11: 115,883,498	E586G	possibly damaging	Het
Pdzk1	C	T	3: 96,869,101	A459V	possibly damaging	Het
Rbpj	A	G	5: 53,651,386	D285G	probably damaging	Het
Rimbp3	T	C	16: 17,211,436	L908P	probably damaging	Het
Samd4b	T	C	7: 28,401,909		probably null	Het
Stau2	C	T	1: 16,345,937	G401S	probably damaging	Het
Trpa1	A	T	1: 14,887,643	I697K	possibly damaging	Het
Ttc17	A	C	2: 94,375,146	V285G	possibly damaging	Het
Unc5b	A	G	10: 60,767,085	F845S	probably damaging	Het
Vmn2r106	T	C	17: 20,278,965	N228S	probably benign	Het
Vps13d	A	G	4: 145,156,266	F919S	possibly damaging	Het
Zbtb38	C	T	9: 96,688,408	V208I	probably benign	Het
Zfp990	A	T	4: 145,536,857	T142S	probably damaging	Het
Zfp990	C	A	4: 145,536,858	T142N	probably damaging	Het

Other mutations in Vmn1r19

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00948:Vmn1r19	APN	6	57405262	missense	probably benign	0.03
IGL01287:Vmn1r19	APN	6	57405194	missense	probably damaging	1.00
IGL01516:Vmn1r19	APN	6	57404872	missense	probably benign	0.03
IGL02676:Vmn1r19	APN	6	57405040	missense	possibly damaging	0.94
IGL03040:Vmn1r19	APN	6	57405362	missense	unknown
IGL03087:Vmn1r19	APN	6	57404491	missense	probably benign	0.01
PIT4802001:Vmn1r19	UTSW	6	57405052	missense	probably damaging	1.00
R0319:Vmn1r19	UTSW	6	57404615	missense	possibly damaging	0.93
R1368:Vmn1r19	UTSW	6	57404671	missense	probably benign	0.01
R1997:Vmn1r19	UTSW	6	57405048	missense	probably damaging	1.00
R2920:Vmn1r19	UTSW	6	57404924	missense	probably benign	0.03
R3857:Vmn1r19	UTSW	6	57405113	missense	possibly damaging	0.68
R4090:Vmn1r19	UTSW	6	57404735	missense	probably damaging	1.00
R4547:Vmn1r19	UTSW	6	57404789	missense	possibly damaging	0.56
R4823:Vmn1r19	UTSW	6	57405234	nonsense	probably null
R4951:Vmn1r19	UTSW	6	57404942	missense	probably benign	0.36
R5077:Vmn1r19	UTSW	6	57405041	missense	probably benign	0.00
R5459:Vmn1r19	UTSW	6	57404490	nonsense	probably null
R5625:Vmn1r19	UTSW	6	57405296	missense	probably damaging	1.00
R5690:Vmn1r19	UTSW	6	57404795	missense	probably benign	0.10
R5761:Vmn1r19	UTSW	6	57405353	missense	unknown
R6124:Vmn1r19	UTSW	6	57404617	missense	probably benign	0.02
R6373:Vmn1r19	UTSW	6	57405332	missense	unknown
R6476:Vmn1r19	UTSW	6	57404593	missense	probably damaging	0.99
R6938:Vmn1r19	UTSW	6	57405007	missense	possibly damaging	0.94
R7027:Vmn1r19	UTSW	6	57404490	nonsense	probably null
R7359:Vmn1r19	UTSW	6	57405095	missense	probably damaging	0.99
R7568:Vmn1r19	UTSW	6	57404828	missense	possibly damaging	0.69
R7893:Vmn1r19	UTSW	6	57404679	missense	probably damaging	1.00
R8481:Vmn1r19	UTSW	6	57404947	missense	probably damaging	0.99
R8487:Vmn1r19	UTSW	6	57405181	missense	probably benign	0.03
R8812:Vmn1r19	UTSW	6	57404451	start gained	probably benign
R8907:Vmn1r19	UTSW	6	57405006	missense	probably benign
R8976:Vmn1r19	UTSW	6	57404734	missense	probably benign	0.01
R9277:Vmn1r19	UTSW	6	57405337	missense	unknown

Posted On

2014-05-07