Incidental Mutation 'IGL01895:Ccdc113'
ID179381
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ccdc113
Ensembl Gene ENSMUSG00000036598
Gene Namecoiled-coil domain containing 113
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.060) question?
Stock #IGL01895
Quality Score
Status
Chromosome8
Chromosomal Location95534085-95558890 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) C to T at 95536458 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000049497 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000041569]
Predicted Effect probably benign
Transcript: ENSMUST00000041569
SMART Domains Protein: ENSMUSP00000049497
Gene: ENSMUSG00000036598

DomainStartEndE-ValueType
coiled coil region 95 139 N/A INTRINSIC
Pfam:DUF4201 178 354 6.2e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2410089E03Rik T A 15: 8,229,107 V2279E possibly damaging Het
Abcc6 A T 7: 46,029,058 I56N possibly damaging Het
Akr1c13 A T 13: 4,205,373 E321V possibly damaging Het
Atp8b3 A T 10: 80,521,828 V1119D possibly damaging Het
Cacna1e G T 1: 154,443,900 F1351L probably damaging Het
Cadps2 A G 6: 23,427,275 W585R probably damaging Het
Ccer1 A T 10: 97,694,050 I192F unknown Het
Chd8 T C 14: 52,199,094 N90S probably benign Het
Clca3a1 A T 3: 144,747,572 C463* probably null Het
Cyp2c65 T A 19: 39,072,232 C179S possibly damaging Het
Dennd4b A G 3: 90,275,567 Q35R probably benign Het
Enpep T C 3: 129,270,334 E928G possibly damaging Het
Fem1c T C 18: 46,505,562 T458A probably benign Het
Fezf2 A T 14: 12,342,498 *456R probably null Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm14085 A C 2: 122,525,091 Y588S possibly damaging Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Iqcm T G 8: 75,888,560 L423R probably damaging Het
Kcnc4 C A 3: 107,448,218 V305L probably benign Het
Kif1a G A 1: 93,025,733 T1337I possibly damaging Het
Lpxn A G 19: 12,833,086 D298G probably damaging Het
Lypd8 A G 11: 58,390,220 T203A possibly damaging Het
Mrps28 C T 3: 8,900,059 V107M probably damaging Het
Myo15b A G 11: 115,883,498 E586G possibly damaging Het
Pdzk1 C T 3: 96,869,101 A459V possibly damaging Het
Rbpj A G 5: 53,651,386 D285G probably damaging Het
Rimbp3 T C 16: 17,211,436 L908P probably damaging Het
Samd4b T C 7: 28,401,909 probably null Het
Stau2 C T 1: 16,345,937 G401S probably damaging Het
Trpa1 A T 1: 14,887,643 I697K possibly damaging Het
Ttc17 A C 2: 94,375,146 V285G possibly damaging Het
Unc5b A G 10: 60,767,085 F845S probably damaging Het
Vmn1r19 A T 6: 57,405,260 Q266L probably benign Het
Vmn2r106 T C 17: 20,278,965 N228S probably benign Het
Vps13d A G 4: 145,156,266 F919S possibly damaging Het
Zbtb38 C T 9: 96,688,408 V208I probably benign Het
Zfp990 A T 4: 145,536,857 T142S probably damaging Het
Zfp990 C A 4: 145,536,858 T142N probably damaging Het
Other mutations in Ccdc113
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01143:Ccdc113 APN 8 95534260 missense probably damaging 0.99
IGL01432:Ccdc113 APN 8 95538257 splice site probably benign
IGL01538:Ccdc113 APN 8 95551238 missense probably benign 0.00
R1219:Ccdc113 UTSW 8 95538267 splice site probably benign
R1891:Ccdc113 UTSW 8 95540916 missense probably damaging 0.99
R1960:Ccdc113 UTSW 8 95540831 missense probably benign 0.00
R1961:Ccdc113 UTSW 8 95540831 missense probably benign 0.00
R1972:Ccdc113 UTSW 8 95538246 missense probably benign 0.06
R2069:Ccdc113 UTSW 8 95557296 missense probably benign 0.05
R3807:Ccdc113 UTSW 8 95542653 missense probably damaging 1.00
R4326:Ccdc113 UTSW 8 95557268 missense probably benign
R5214:Ccdc113 UTSW 8 95545973 missense possibly damaging 0.91
R5290:Ccdc113 UTSW 8 95540796 splice site probably null
R6394:Ccdc113 UTSW 8 95557192 missense probably benign 0.26
R6615:Ccdc113 UTSW 8 95545992 missense probably benign 0.03
R7088:Ccdc113 UTSW 8 95538105 missense probably benign 0.03
R7751:Ccdc113 UTSW 8 95538201 missense possibly damaging 0.53
R8139:Ccdc113 UTSW 8 95558738 missense possibly damaging 0.89
RF016:Ccdc113 UTSW 8 95538105 missense probably benign 0.03
Z1176:Ccdc113 UTSW 8 95538219 missense probably damaging 0.96
Posted On2014-05-07