Incidental Mutation 'IGL01896:9330159F19Rik'
ID179410
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 9330159F19Rik
Ensembl Gene ENSMUSG00000004360
Gene NameRIKEN cDNA 9330159F19 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.061) question?
Stock #IGL01896
Quality Score
Status
Chromosome10
Chromosomal Location29211606-29230779 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 29225158 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Tyrosine at position 509 (F509Y)
Ref Sequence ENSEMBL: ENSMUSP00000151062 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000092627] [ENSMUST00000213489] [ENSMUST00000213490] [ENSMUST00000217011]
Predicted Effect possibly damaging
Transcript: ENSMUST00000092627
AA Change: F509Y

PolyPhen 2 Score 0.838 (Sensitivity: 0.84; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000090291
Gene: ENSMUSG00000004360
AA Change: F509Y

DomainStartEndE-ValueType
Pfam:DUF4482 15 152 3e-43 PFAM
low complexity region 270 286 N/A INTRINSIC
low complexity region 616 635 N/A INTRINSIC
Predicted Effect possibly damaging
Transcript: ENSMUST00000213489
AA Change: F509Y

PolyPhen 2 Score 0.838 (Sensitivity: 0.84; Specificity: 0.93)
Predicted Effect probably benign
Transcript: ENSMUST00000213490
Predicted Effect probably benign
Transcript: ENSMUST00000217011
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acot11 T A 4: 106,771,367 I75F probably damaging Het
Atp1a2 T A 1: 172,286,011 N427Y probably damaging Het
Cd19 T C 7: 126,414,350 D89G possibly damaging Het
Clca1 T A 3: 145,015,677 T378S possibly damaging Het
Cltc A T 11: 86,725,133 C436S probably damaging Het
Def8 G A 8: 123,459,895 V429M probably benign Het
Dnah9 A T 11: 66,130,666 D311E possibly damaging Het
Dpy19l4 T C 4: 11,267,752 K396R possibly damaging Het
Eif4b T C 15: 102,095,286 S597P probably benign Het
Ezh1 A T 11: 101,213,755 N155K probably benign Het
Glud1 A G 14: 34,319,905 S157G probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Gm5600 T C 7: 113,707,984 noncoding transcript Het
Hnf4g T A 3: 3,651,410 V298E probably damaging Het
Hspd1 C T 1: 55,079,109 R446Q probably benign Het
Lyst A G 13: 13,635,577 I611V probably benign Het
Map4k3 T C 17: 80,613,931 E524G probably benign Het
Mepe A G 5: 104,338,269 D425G possibly damaging Het
Myo1a G T 10: 127,719,904 V921L probably benign Het
Plxdc1 A T 11: 97,924,582 M470K probably damaging Het
Prim1 A G 10: 128,022,889 Y222C probably damaging Het
Ptpn13 A G 5: 103,501,523 N264S possibly damaging Het
Qrsl1 T C 10: 43,876,504 D441G probably benign Het
Samd9l G T 6: 3,375,120 Q714K probably benign Het
Scrib T C 15: 76,066,118 E293G possibly damaging Het
Slc12a2 T A 18: 57,896,308 N255K probably benign Het
Slc6a6 T C 6: 91,726,069 I141T probably damaging Het
Slc9a1 T C 4: 133,418,059 L485P probably damaging Het
Slfn8 A T 11: 83,003,696 Y706N probably damaging Het
Tlr5 T C 1: 182,974,879 F583L possibly damaging Het
Tmprss15 A G 16: 79,090,790 V43A probably benign Het
Ttc24 T C 3: 88,070,413 probably null Het
Ttc7 A G 17: 87,359,124 T606A probably damaging Het
Ubap2 G T 4: 41,202,362 P689T possibly damaging Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Wfdc8 A T 2: 164,605,780 M120K probably damaging Het
Other mutations in 9330159F19Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00958:9330159F19Rik APN 10 29227328 missense probably benign 0.13
IGL01766:9330159F19Rik APN 10 29224561 missense probably benign 0.00
IGL01988:9330159F19Rik APN 10 29225111 missense probably benign 0.08
IGL03007:9330159F19Rik APN 10 29222038 missense possibly damaging 0.66
PIT1430001:9330159F19Rik UTSW 10 29224715 missense probably damaging 1.00
R0256:9330159F19Rik UTSW 10 29222256 missense probably damaging 1.00
R0490:9330159F19Rik UTSW 10 29227342 missense probably damaging 0.99
R1755:9330159F19Rik UTSW 10 29222294 missense possibly damaging 0.92
R1759:9330159F19Rik UTSW 10 29218276 missense possibly damaging 0.51
R1836:9330159F19Rik UTSW 10 29221799 missense probably damaging 0.98
R2373:9330159F19Rik UTSW 10 29225043 missense probably benign 0.00
R2511:9330159F19Rik UTSW 10 29221906 missense probably damaging 0.96
R3113:9330159F19Rik UTSW 10 29224376 nonsense probably null
R3755:9330159F19Rik UTSW 10 29222114 missense probably damaging 0.98
R3954:9330159F19Rik UTSW 10 29224809 missense possibly damaging 0.92
R3956:9330159F19Rik UTSW 10 29224809 missense possibly damaging 0.92
R3957:9330159F19Rik UTSW 10 29224809 missense possibly damaging 0.92
R4321:9330159F19Rik UTSW 10 29224891 missense probably damaging 1.00
R4510:9330159F19Rik UTSW 10 29224823 missense probably benign
R4511:9330159F19Rik UTSW 10 29224823 missense probably benign
R4717:9330159F19Rik UTSW 10 29221787 missense probably damaging 1.00
R5336:9330159F19Rik UTSW 10 29224499 missense probably damaging 0.98
R5401:9330159F19Rik UTSW 10 29225140 missense probably benign 0.03
R5585:9330159F19Rik UTSW 10 29225275 missense possibly damaging 0.95
R5635:9330159F19Rik UTSW 10 29218277 missense possibly damaging 0.93
R5647:9330159F19Rik UTSW 10 29225254 missense probably damaging 0.99
R6831:9330159F19Rik UTSW 10 29224679 missense probably benign 0.44
R7085:9330159F19Rik UTSW 10 29224480 missense probably damaging 0.96
R7779:9330159F19Rik UTSW 10 29225320 missense probably damaging 1.00
R7813:9330159F19Rik UTSW 10 29224900 missense probably benign 0.41
Posted On2014-05-07