Incidental Mutation 'IGL01909:Vmn2r37'
ID179746
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r37
Ensembl Gene ENSMUSG00000066828
Gene Namevomeronasal 2, receptor 37
SynonymsV2r14
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.085) question?
Stock #IGL01909
Quality Score
Status
Chromosome7
Chromosomal Location9205546-9223653 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 9216033 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Stop codon at position 451 (K451*)
Ref Sequence ENSEMBL: ENSMUSP00000072566 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072787]
Predicted Effect probably null
Transcript: ENSMUST00000072787
AA Change: K451*
SMART Domains Protein: ENSMUSP00000072566
Gene: ENSMUSG00000066828
AA Change: K451*

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 157 469 2.9e-26 PFAM
Pfam:NCD3G 512 563 1.1e-16 PFAM
Pfam:7tm_3 550 783 1.7e-53 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700111E14Rik A T 6: 36,937,217 probably benign Het
Actn2 A T 13: 12,309,593 probably null Het
Apom C T 17: 35,131,232 A78T probably benign Het
Bambi A G 18: 3,508,229 Y7C possibly damaging Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
Cdc42bpb T C 12: 111,323,142 M418V probably benign Het
Clptm1 T C 7: 19,655,776 N43D probably benign Het
Cspp1 T C 1: 10,066,661 V241A probably benign Het
Ctnna3 T A 10: 63,504,131 I32N probably benign Het
Elp2 A G 18: 24,619,519 probably benign Het
Frmd4a A G 2: 4,604,033 D893G probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Gm5862 A C 5: 26,022,771 W41G probably benign Het
H2-M10.1 C A 17: 36,325,079 G154* probably null Het
Igdcc3 C T 9: 65,144,537 R141W probably damaging Het
Igkv14-130 A G 6: 67,791,339 K60E possibly damaging Het
Kcnmb2 A G 3: 32,198,363 probably benign Het
Lrp4 T C 2: 91,494,184 L1288P possibly damaging Het
Mavs T A 2: 131,245,521 M313K probably benign Het
Mia2 A G 12: 59,107,945 E148G possibly damaging Het
Olfr26 T A 9: 38,855,717 Y218* probably null Het
Olfr813 A T 10: 129,857,081 T188S probably damaging Het
Olfr875 T A 9: 37,772,863 I68K possibly damaging Het
Plekha3 C T 2: 76,686,703 T133M probably damaging Het
Plxna1 A T 6: 89,332,084 probably null Het
Sept2 A G 1: 93,499,101 N144S probably damaging Het
Slc9a4 T C 1: 40,612,291 probably benign Het
Slco1b2 T A 6: 141,648,586 I59K probably damaging Het
Tnrc6b A G 15: 80,901,983 S1243G possibly damaging Het
Unc13a T A 8: 71,639,210 probably benign Het
Vmn2r105 T C 17: 20,224,656 R525G probably damaging Het
Vmn2r71 C T 7: 85,620,793 T504I probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Zfp668 A T 7: 127,866,822 C397S probably damaging Het
Other mutations in Vmn2r37
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01346:Vmn2r37 APN 7 9206681 missense probably benign 0.05
IGL02281:Vmn2r37 APN 7 9217882 missense possibly damaging 0.95
IGL02282:Vmn2r37 APN 7 9206762 missense probably benign 0.19
IGL02513:Vmn2r37 APN 7 9217935 missense probably benign 0.14
R0136:Vmn2r37 UTSW 7 9217783 nonsense probably null
R2051:Vmn2r37 UTSW 7 9217793 missense probably damaging 1.00
R2262:Vmn2r37 UTSW 7 9217944 missense probably damaging 0.99
R3158:Vmn2r37 UTSW 7 9217714 missense probably benign 0.03
R4084:Vmn2r37 UTSW 7 9215985 missense probably benign
R4114:Vmn2r37 UTSW 7 9210093 critical splice acceptor site probably null
R5231:Vmn2r37 UTSW 7 9206595 missense possibly damaging 0.94
R5462:Vmn2r37 UTSW 7 9217974 missense probably damaging 1.00
R6437:Vmn2r37 UTSW 7 9217851 missense probably damaging 0.98
R7104:Vmn2r37 UTSW 7 9216046 missense probably damaging 1.00
R7116:Vmn2r37 UTSW 7 9217899 missense probably benign 0.00
R7381:Vmn2r37 UTSW 7 9210033 missense probably benign 0.21
RF004:Vmn2r37 UTSW 7 9217687 missense probably damaging 0.97
Z1177:Vmn2r37 UTSW 7 9209997 missense probably damaging 1.00
Posted On2014-05-07