Incidental Mutation 'IGL01910:Slc17a1'
ID179792
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc17a1
Ensembl Gene ENSMUSG00000021335
Gene Namesolute carrier family 17 (sodium phosphate), member 1
SynonymsNpt1, NAPI-1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL01910
Quality Score
Status
Chromosome13
Chromosomal Location23867750-23895730 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to G at 23878457 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000120824 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000006785] [ENSMUST00000110413] [ENSMUST00000130211]
Predicted Effect probably benign
Transcript: ENSMUST00000006785
SMART Domains Protein: ENSMUSP00000006785
Gene: ENSMUSG00000021335

DomainStartEndE-ValueType
Pfam:MFS_1 24 412 2.7e-48 PFAM
transmembrane domain 430 449 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000110413
SMART Domains Protein: ENSMUSP00000106043
Gene: ENSMUSG00000021335

DomainStartEndE-ValueType
Pfam:MFS_1 24 412 3.1e-48 PFAM
transmembrane domain 430 449 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000129042
Predicted Effect probably benign
Transcript: ENSMUST00000130211
SMART Domains Protein: ENSMUSP00000120824
Gene: ENSMUSG00000021335

DomainStartEndE-ValueType
transmembrane domain 13 35 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ammecr1l A G 18: 31,771,942 M79V probably benign Het
Arhgap5 T A 12: 52,516,861 V205E probably benign Het
BC061237 T C 14: 44,505,988 probably benign Het
Calr T A 8: 84,844,969 probably benign Het
Celsr1 T C 15: 85,929,895 N1942S probably benign Het
Cfap100 T C 6: 90,409,624 D373G probably damaging Het
Chst9 C A 18: 15,452,874 A211S possibly damaging Het
Ephb1 T C 9: 102,001,857 E478G probably benign Het
Fbrsl1 A T 5: 110,363,736 V387D probably damaging Het
Fxyd5 T C 7: 31,035,218 I161V probably damaging Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Hmx2 C T 7: 131,555,672 R172C probably damaging Het
Itgam C T 7: 128,083,776 A320V probably damaging Het
Macrod2 T A 2: 142,296,565 N361K probably benign Het
Mbl1 T C 14: 41,153,746 probably null Het
Nudt9 G A 5: 104,054,309 G79R probably damaging Het
Ppan C T 9: 20,890,936 R208C probably damaging Het
Rpl23a-ps1 A G 1: 45,981,780 noncoding transcript Het
Tep1 T C 14: 50,844,112 T1269A probably benign Het
Vmn2r16 A T 5: 109,340,085 N275Y probably damaging Het
Wdr93 T C 7: 79,771,573 S405P probably damaging Het
Xcl1 T A 1: 164,931,889 I81F probably damaging Het
Other mutations in Slc17a1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00972:Slc17a1 APN 13 23878454 unclassified probably benign
IGL01453:Slc17a1 APN 13 23874731 missense probably damaging 0.99
IGL01560:Slc17a1 APN 13 23874629 missense probably damaging 0.99
R1077:Slc17a1 UTSW 13 23878450 unclassified probably benign
R1939:Slc17a1 UTSW 13 23875881 missense probably benign 0.05
R2016:Slc17a1 UTSW 13 23878539 missense probably benign 0.03
R2134:Slc17a1 UTSW 13 23875675 nonsense probably null
R3001:Slc17a1 UTSW 13 23878581 critical splice donor site probably null
R3002:Slc17a1 UTSW 13 23878581 critical splice donor site probably null
R4559:Slc17a1 UTSW 13 23878712 nonsense probably null
R4580:Slc17a1 UTSW 13 23887977 missense probably damaging 1.00
R4658:Slc17a1 UTSW 13 23878560 missense probably benign
R4696:Slc17a1 UTSW 13 23880717 missense probably damaging 1.00
R4716:Slc17a1 UTSW 13 23880593 missense probably benign 0.05
R4845:Slc17a1 UTSW 13 23876618 missense probably damaging 1.00
R4878:Slc17a1 UTSW 13 23880654 missense probably damaging 1.00
R5517:Slc17a1 UTSW 13 23872592 utr 5 prime probably benign
R6020:Slc17a1 UTSW 13 23875610 missense possibly damaging 0.70
R7403:Slc17a1 UTSW 13 23874707 missense probably benign
R7440:Slc17a1 UTSW 13 23878483 missense possibly damaging 0.62
R7747:Slc17a1 UTSW 13 23888052 missense probably benign 0.10
R8063:Slc17a1 UTSW 13 23875541 missense probably benign 0.33
Posted On2014-05-07