Incidental Mutation 'IGL01917:Olfr596'
ID179976
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr596
Ensembl Gene ENSMUSG00000073953
Gene Nameolfactory receptor 596
SynonymsOlfr596-ps1, Gm15117, ENSMUSG00000073953, GA_x6K02T2PBJ9-6019769-6019943
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.077) question?
Stock #IGL01917
Quality Score
Status
Chromosome7
Chromosomal Location103305648-103312782 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 103310357 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Stop codon at position 212 (L212*)
Ref Sequence ENSEMBL: ENSMUSP00000149187 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000104880] [ENSMUST00000214577]
Predicted Effect probably null
Transcript: ENSMUST00000104880
AA Change: L212*
SMART Domains Protein: ENSMUSP00000100475
Gene: ENSMUSG00000073953
AA Change: L212*

DomainStartEndE-ValueType
Pfam:7tm_4 33 311 1.5e-121 PFAM
Pfam:7TM_GPCR_Srsx 37 210 5.1e-11 PFAM
Pfam:7tm_1 43 293 1.6e-15 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000214577
AA Change: L212*
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abt1 A T 13: 23,423,789 M15K unknown Het
Adal A G 2: 121,142,554 S31G possibly damaging Het
C2cd5 T C 6: 143,072,596 Y300C probably benign Het
Chia1 T A 3: 106,128,220 V184E probably damaging Het
Fat4 T A 3: 38,889,730 V924D possibly damaging Het
Fstl5 A T 3: 76,707,846 H738L probably damaging Het
Gimap4 T C 6: 48,690,920 M75T probably benign Het
Gm10238 A T 15: 75,237,712 noncoding transcript Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Gm5862 A C 5: 26,022,771 W41G probably benign Het
Gsdmc A G 15: 63,778,585 Y307H probably benign Het
Iqub A G 6: 24,479,319 L408P probably damaging Het
Lbx1 T A 19: 45,234,213 K124* probably null Het
Naip2 C A 13: 100,162,083 V482L probably benign Het
Pdcd11 C A 19: 47,101,165 Q325K possibly damaging Het
Pik3c3 T A 18: 30,274,446 S82R probably damaging Het
Pramef6 T A 4: 143,897,714 E71V probably benign Het
Prickle1 T C 15: 93,503,527 K359E probably damaging Het
Ptprj A G 2: 90,469,749 V236A probably damaging Het
Serpinb3d T A 1: 107,079,681 T192S probably damaging Het
Usp31 T C 7: 121,679,485 N219S probably benign Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Other mutations in Olfr596
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00814:Olfr596 APN 7 103309807 missense probably benign 0.03
G1patch:Olfr596 UTSW 7 103310354 missense probably damaging 1.00
R0601:Olfr596 UTSW 7 103310164 missense probably damaging 1.00
R0908:Olfr596 UTSW 7 103310573 missense possibly damaging 0.56
R1762:Olfr596 UTSW 7 103310221 missense probably damaging 1.00
R1772:Olfr596 UTSW 7 103310242 missense possibly damaging 0.94
R1806:Olfr596 UTSW 7 103310225 missense probably damaging 1.00
R2035:Olfr596 UTSW 7 103310256 missense probably damaging 1.00
R2365:Olfr596 UTSW 7 103310173 missense probably benign 0.00
R3827:Olfr596 UTSW 7 103309802 missense probably benign 0.12
R4241:Olfr596 UTSW 7 103310661 makesense probably null
R4619:Olfr596 UTSW 7 103309958 missense probably benign 0.04
R4620:Olfr596 UTSW 7 103309958 missense probably benign 0.04
R6279:Olfr596 UTSW 7 103310429 missense probably benign
R6300:Olfr596 UTSW 7 103310429 missense probably benign
R6505:Olfr596 UTSW 7 103309793 missense probably benign 0.00
R6725:Olfr596 UTSW 7 103310354 missense probably damaging 1.00
R7175:Olfr596 UTSW 7 103309847 missense probably benign 0.22
R7708:Olfr596 UTSW 7 103310561 missense probably damaging 1.00
R8855:Olfr596 UTSW 7 103309961 missense probably damaging 1.00
Posted On2014-05-07